Use of antenatal corticosteroids at health facilities and communities in low-and-middle income countries
- Autores
- Berrueta, Amanda Mabel; Hemingway Foday, Jennifer; Thorsten, Vanessa R.; Goldenberg, Robert L.; Carlo, Waldemar A.; Garces, Ana; Patel, Archana; Saleem, Sarah; Pasha, Omrana; Chomba, Elwyn; Hibberd, Patricia L.; Krebs, Nancy F.; Goudar, Shivaprasad; Derman, Richard J.; Esamai, Fabian; Liechty, Edward A.; Moore, Janet L.; McClure, Elizabeth M.; Koso Thomas, Marion; Buekens, Pierre; Belizan, Jose; Althabe, Fernando
- Año de publicación
- 2016
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- BACKGROUND:Antenatal corticosteroids (ACS) for women at high risk of preterm birth is an effective intervention to reduce neonatal mortality among preterm babies delivered in hospital settings, but has not been widely used in low-middle resource settings. We sought to assess the rates of ACS use at all levels of health care in low and middle income countries (LMIC).METHODS:We assessed rates of ACS in 7 sites in 6 LMIC participating in the Eunice Kennedy Shriver National Institute of Child Health and Human Development´s Global Network for Women and Children´s Health Research Antenatal Corticosteroids Trial (ACT), a cluster-randomized trial to assess the feasibility, effectiveness, and safety of a multifaceted intervention designed to increase the use of ACS. We conducted this analysis using data from the control clusters, which did not receive any components of the intervention and intended to follow usual care. We included women who delivered an infant with a birth weight <5th percentile, a proxy for preterm birth, and were enrolled in the Maternal Newborn Health (MNH) Registry between October 2011 and March 2014 in all clusters. A survey of the site investigators regarding existing policies on ACS in health facilities and for health workers in the community was part of pre-trial activities.RESULTS:Overall, of 51,523 women delivered in control clusters across all sites, the percentage of <5th percentile babies ranged from 3.5 % in Kenya to 10.7 % in Pakistan. There was variation among the sites in the use of ACS at all hospitals and among those hospitals having cesarean section and neonatal care capabilities (bag and mask and oxygen or mechanical ventilation). Rates of ACS use for <5th percentile babies in all hospitals ranged from 3.8 % in the Kenya sites to 44.5 % in the Argentina site, and in hospitals with cesarean section and neonatal care capabilities from 0 % in Zambia to 43.5 % in Argentina. ACS were rarely used in clinic or home deliveries at any site. Guidelines for ACS use at all levels of the health system were available for most of the sites.CONCLUSION:Our study reports an overall low utilization of ACS among mothers of <5th percentile infants in hospital and clinic deliveries in LMIC.
Fil: Berrueta, Amanda Mabel. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Hemingway Foday, Jennifer. University Of Durham; Reino Unido
Fil: Thorsten, Vanessa R.. University Of Durham; Reino Unido
Fil: Goldenberg, Robert L.. Columbia University; Estados Unidos
Fil: Carlo, Waldemar A.. University of Alabama at Birmingahm; Estados Unidos
Fil: Garces, Ana. Fundación para la Alimentación y Nutrición de Centro América y Panamá; Guatemala
Fil: Patel, Archana. Lata Medical Research Foundation, Indira Gandhi Government Medical College; India
Fil: Saleem, Sarah. Aga Khan University. Department of Community Health Sciences, ; Pakistán
Fil: Pasha, Omrana. Aga Khan University. Department of Community Health Sciences, ; Pakistán
Fil: Chomba, Elwyn. University Teaching Hospital; Zambia
Fil: Hibberd, Patricia L.. Massachusetts General Hospital; Estados Unidos
Fil: Krebs, Nancy F.. 0University of Colorado School of Medicine; Estados Unidos
Fil: Goudar, Shivaprasad. KLE University’s Jawaharlal Nehru Medical College,; India
Fil: Derman, Richard J.. 2Christiana Health Care; Estados Unidos
Fil: Esamai, Fabian. Moi University School of Medicine; Kenia
Fil: Liechty, Edward A.. Indiana University; Estados Unidos
Fil: Moore, Janet L.. University Of Durham; Reino Unido
Fil: McClure, Elizabeth M.. University Of Durham; Reino Unido
Fil: Koso Thomas, Marion. Eunice Kennedy Shriver National Institute of Child Health and Human Development; Estados Unidos
Fil: Buekens, Pierre. Tulane School of Public Health & Tropical Medicine; Estados Unidos
Fil: Belizan, Jose. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Althabe, Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Efectividad Clínica y Sanitaria; Argentina - Materia
- Corticosteroids
- Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
.jpg)
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/48881
Ver los metadatos del registro completo
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Use of antenatal corticosteroids at health facilities and communities in low-and-middle income countriesBerrueta, Amanda MabelHemingway Foday, JenniferThorsten, Vanessa R.Goldenberg, Robert L.Carlo, Waldemar A.Garces, AnaPatel, ArchanaSaleem, SarahPasha, OmranaChomba, ElwynHibberd, Patricia L.Krebs, Nancy F.Goudar, ShivaprasadDerman, Richard J.Esamai, FabianLiechty, Edward A.Moore, Janet L.McClure, Elizabeth M.Koso Thomas, MarionBuekens, PierreBelizan, JoseAlthabe, FernandoCorticosteroidshttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3BACKGROUND:Antenatal corticosteroids (ACS) for women at high risk of preterm birth is an effective intervention to reduce neonatal mortality among preterm babies delivered in hospital settings, but has not been widely used in low-middle resource settings. We sought to assess the rates of ACS use at all levels of health care in low and middle income countries (LMIC).METHODS:We assessed rates of ACS in 7 sites in 6 LMIC participating in the Eunice Kennedy Shriver National Institute of Child Health and Human Development´s Global Network for Women and Children´s Health Research Antenatal Corticosteroids Trial (ACT), a cluster-randomized trial to assess the feasibility, effectiveness, and safety of a multifaceted intervention designed to increase the use of ACS. We conducted this analysis using data from the control clusters, which did not receive any components of the intervention and intended to follow usual care. We included women who delivered an infant with a birth weight <5th percentile, a proxy for preterm birth, and were enrolled in the Maternal Newborn Health (MNH) Registry between October 2011 and March 2014 in all clusters. A survey of the site investigators regarding existing policies on ACS in health facilities and for health workers in the community was part of pre-trial activities.RESULTS:Overall, of 51,523 women delivered in control clusters across all sites, the percentage of <5th percentile babies ranged from 3.5 % in Kenya to 10.7 % in Pakistan. There was variation among the sites in the use of ACS at all hospitals and among those hospitals having cesarean section and neonatal care capabilities (bag and mask and oxygen or mechanical ventilation). Rates of ACS use for <5th percentile babies in all hospitals ranged from 3.8 % in the Kenya sites to 44.5 % in the Argentina site, and in hospitals with cesarean section and neonatal care capabilities from 0 % in Zambia to 43.5 % in Argentina. ACS were rarely used in clinic or home deliveries at any site. Guidelines for ACS use at all levels of the health system were available for most of the sites.CONCLUSION:Our study reports an overall low utilization of ACS among mothers of <5th percentile infants in hospital and clinic deliveries in LMIC.Fil: Berrueta, Amanda Mabel. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Hemingway Foday, Jennifer. University Of Durham; Reino UnidoFil: Thorsten, Vanessa R.. University Of Durham; Reino UnidoFil: Goldenberg, Robert L.. Columbia University; Estados UnidosFil: Carlo, Waldemar A.. University of Alabama at Birmingahm; Estados UnidosFil: Garces, Ana. Fundación para la Alimentación y Nutrición de Centro América y Panamá; GuatemalaFil: Patel, Archana. Lata Medical Research Foundation, Indira Gandhi Government Medical College; IndiaFil: Saleem, Sarah. Aga Khan University. Department of Community Health Sciences, ; PakistánFil: Pasha, Omrana. Aga Khan University. Department of Community Health Sciences, ; PakistánFil: Chomba, Elwyn. University Teaching Hospital; ZambiaFil: Hibberd, Patricia L.. Massachusetts General Hospital; Estados UnidosFil: Krebs, Nancy F.. 0University of Colorado School of Medicine; Estados UnidosFil: Goudar, Shivaprasad. KLE University’s Jawaharlal Nehru Medical College,; IndiaFil: Derman, Richard J.. 2Christiana Health Care; Estados UnidosFil: Esamai, Fabian. Moi University School of Medicine; KeniaFil: Liechty, Edward A.. Indiana University; Estados UnidosFil: Moore, Janet L.. University Of Durham; Reino UnidoFil: McClure, Elizabeth M.. University Of Durham; Reino UnidoFil: Koso Thomas, Marion. Eunice Kennedy Shriver National Institute of Child Health and Human Development; Estados UnidosFil: Buekens, Pierre. Tulane School of Public Health & Tropical Medicine; Estados UnidosFil: Belizan, Jose. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Althabe, Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Efectividad Clínica y Sanitaria; ArgentinaBioMed Central2016-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/48881Berrueta, Amanda Mabel; Hemingway Foday, Jennifer; Thorsten, Vanessa R.; Goldenberg, Robert L.; Carlo, Waldemar A.; et al.; Use of antenatal corticosteroids at health facilities and communities in low-and-middle income countries; BioMed Central; Reproductive Health; 13; 1; 5-2016; 1-61471-2458CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1186/s12978-016-0176-2info:eu-repo/semantics/altIdentifier/url/https://reproductive-health-journal.biomedcentral.com/articles/10.1186/s12978-016-0176-2info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:02:57Zoai:ri.conicet.gov.ar:11336/48881instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:02:57.722CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
| dc.title.none.fl_str_mv |
Use of antenatal corticosteroids at health facilities and communities in low-and-middle income countries |
| title |
Use of antenatal corticosteroids at health facilities and communities in low-and-middle income countries |
| spellingShingle |
Use of antenatal corticosteroids at health facilities and communities in low-and-middle income countries Berrueta, Amanda Mabel Corticosteroids |
| title_short |
Use of antenatal corticosteroids at health facilities and communities in low-and-middle income countries |
| title_full |
Use of antenatal corticosteroids at health facilities and communities in low-and-middle income countries |
| title_fullStr |
Use of antenatal corticosteroids at health facilities and communities in low-and-middle income countries |
| title_full_unstemmed |
Use of antenatal corticosteroids at health facilities and communities in low-and-middle income countries |
| title_sort |
Use of antenatal corticosteroids at health facilities and communities in low-and-middle income countries |
| dc.creator.none.fl_str_mv |
Berrueta, Amanda Mabel Hemingway Foday, Jennifer Thorsten, Vanessa R. Goldenberg, Robert L. Carlo, Waldemar A. Garces, Ana Patel, Archana Saleem, Sarah Pasha, Omrana Chomba, Elwyn Hibberd, Patricia L. Krebs, Nancy F. Goudar, Shivaprasad Derman, Richard J. Esamai, Fabian Liechty, Edward A. Moore, Janet L. McClure, Elizabeth M. Koso Thomas, Marion Buekens, Pierre Belizan, Jose Althabe, Fernando |
| author |
Berrueta, Amanda Mabel |
| author_facet |
Berrueta, Amanda Mabel Hemingway Foday, Jennifer Thorsten, Vanessa R. Goldenberg, Robert L. Carlo, Waldemar A. Garces, Ana Patel, Archana Saleem, Sarah Pasha, Omrana Chomba, Elwyn Hibberd, Patricia L. Krebs, Nancy F. Goudar, Shivaprasad Derman, Richard J. Esamai, Fabian Liechty, Edward A. Moore, Janet L. McClure, Elizabeth M. Koso Thomas, Marion Buekens, Pierre Belizan, Jose Althabe, Fernando |
| author_role |
author |
| author2 |
Hemingway Foday, Jennifer Thorsten, Vanessa R. Goldenberg, Robert L. Carlo, Waldemar A. Garces, Ana Patel, Archana Saleem, Sarah Pasha, Omrana Chomba, Elwyn Hibberd, Patricia L. Krebs, Nancy F. Goudar, Shivaprasad Derman, Richard J. Esamai, Fabian Liechty, Edward A. Moore, Janet L. McClure, Elizabeth M. Koso Thomas, Marion Buekens, Pierre Belizan, Jose Althabe, Fernando |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author |
| dc.subject.none.fl_str_mv |
Corticosteroids |
| topic |
Corticosteroids |
| purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.3 https://purl.org/becyt/ford/3 |
| dc.description.none.fl_txt_mv |
BACKGROUND:Antenatal corticosteroids (ACS) for women at high risk of preterm birth is an effective intervention to reduce neonatal mortality among preterm babies delivered in hospital settings, but has not been widely used in low-middle resource settings. We sought to assess the rates of ACS use at all levels of health care in low and middle income countries (LMIC).METHODS:We assessed rates of ACS in 7 sites in 6 LMIC participating in the Eunice Kennedy Shriver National Institute of Child Health and Human Development´s Global Network for Women and Children´s Health Research Antenatal Corticosteroids Trial (ACT), a cluster-randomized trial to assess the feasibility, effectiveness, and safety of a multifaceted intervention designed to increase the use of ACS. We conducted this analysis using data from the control clusters, which did not receive any components of the intervention and intended to follow usual care. We included women who delivered an infant with a birth weight <5th percentile, a proxy for preterm birth, and were enrolled in the Maternal Newborn Health (MNH) Registry between October 2011 and March 2014 in all clusters. A survey of the site investigators regarding existing policies on ACS in health facilities and for health workers in the community was part of pre-trial activities.RESULTS:Overall, of 51,523 women delivered in control clusters across all sites, the percentage of <5th percentile babies ranged from 3.5 % in Kenya to 10.7 % in Pakistan. There was variation among the sites in the use of ACS at all hospitals and among those hospitals having cesarean section and neonatal care capabilities (bag and mask and oxygen or mechanical ventilation). Rates of ACS use for <5th percentile babies in all hospitals ranged from 3.8 % in the Kenya sites to 44.5 % in the Argentina site, and in hospitals with cesarean section and neonatal care capabilities from 0 % in Zambia to 43.5 % in Argentina. ACS were rarely used in clinic or home deliveries at any site. Guidelines for ACS use at all levels of the health system were available for most of the sites.CONCLUSION:Our study reports an overall low utilization of ACS among mothers of <5th percentile infants in hospital and clinic deliveries in LMIC. Fil: Berrueta, Amanda Mabel. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Hemingway Foday, Jennifer. University Of Durham; Reino Unido Fil: Thorsten, Vanessa R.. University Of Durham; Reino Unido Fil: Goldenberg, Robert L.. Columbia University; Estados Unidos Fil: Carlo, Waldemar A.. University of Alabama at Birmingahm; Estados Unidos Fil: Garces, Ana. Fundación para la Alimentación y Nutrición de Centro América y Panamá; Guatemala Fil: Patel, Archana. Lata Medical Research Foundation, Indira Gandhi Government Medical College; India Fil: Saleem, Sarah. Aga Khan University. Department of Community Health Sciences, ; Pakistán Fil: Pasha, Omrana. Aga Khan University. Department of Community Health Sciences, ; Pakistán Fil: Chomba, Elwyn. University Teaching Hospital; Zambia Fil: Hibberd, Patricia L.. Massachusetts General Hospital; Estados Unidos Fil: Krebs, Nancy F.. 0University of Colorado School of Medicine; Estados Unidos Fil: Goudar, Shivaprasad. KLE University’s Jawaharlal Nehru Medical College,; India Fil: Derman, Richard J.. 2Christiana Health Care; Estados Unidos Fil: Esamai, Fabian. Moi University School of Medicine; Kenia Fil: Liechty, Edward A.. Indiana University; Estados Unidos Fil: Moore, Janet L.. University Of Durham; Reino Unido Fil: McClure, Elizabeth M.. University Of Durham; Reino Unido Fil: Koso Thomas, Marion. Eunice Kennedy Shriver National Institute of Child Health and Human Development; Estados Unidos Fil: Buekens, Pierre. Tulane School of Public Health & Tropical Medicine; Estados Unidos Fil: Belizan, Jose. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Althabe, Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Efectividad Clínica y Sanitaria; Argentina |
| description |
BACKGROUND:Antenatal corticosteroids (ACS) for women at high risk of preterm birth is an effective intervention to reduce neonatal mortality among preterm babies delivered in hospital settings, but has not been widely used in low-middle resource settings. We sought to assess the rates of ACS use at all levels of health care in low and middle income countries (LMIC).METHODS:We assessed rates of ACS in 7 sites in 6 LMIC participating in the Eunice Kennedy Shriver National Institute of Child Health and Human Development´s Global Network for Women and Children´s Health Research Antenatal Corticosteroids Trial (ACT), a cluster-randomized trial to assess the feasibility, effectiveness, and safety of a multifaceted intervention designed to increase the use of ACS. We conducted this analysis using data from the control clusters, which did not receive any components of the intervention and intended to follow usual care. We included women who delivered an infant with a birth weight <5th percentile, a proxy for preterm birth, and were enrolled in the Maternal Newborn Health (MNH) Registry between October 2011 and March 2014 in all clusters. A survey of the site investigators regarding existing policies on ACS in health facilities and for health workers in the community was part of pre-trial activities.RESULTS:Overall, of 51,523 women delivered in control clusters across all sites, the percentage of <5th percentile babies ranged from 3.5 % in Kenya to 10.7 % in Pakistan. There was variation among the sites in the use of ACS at all hospitals and among those hospitals having cesarean section and neonatal care capabilities (bag and mask and oxygen or mechanical ventilation). Rates of ACS use for <5th percentile babies in all hospitals ranged from 3.8 % in the Kenya sites to 44.5 % in the Argentina site, and in hospitals with cesarean section and neonatal care capabilities from 0 % in Zambia to 43.5 % in Argentina. ACS were rarely used in clinic or home deliveries at any site. Guidelines for ACS use at all levels of the health system were available for most of the sites.CONCLUSION:Our study reports an overall low utilization of ACS among mothers of <5th percentile infants in hospital and clinic deliveries in LMIC. |
| publishDate |
2016 |
| dc.date.none.fl_str_mv |
2016-05 |
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info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
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article |
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publishedVersion |
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http://hdl.handle.net/11336/48881 Berrueta, Amanda Mabel; Hemingway Foday, Jennifer; Thorsten, Vanessa R.; Goldenberg, Robert L.; Carlo, Waldemar A.; et al.; Use of antenatal corticosteroids at health facilities and communities in low-and-middle income countries; BioMed Central; Reproductive Health; 13; 1; 5-2016; 1-6 1471-2458 CONICET Digital CONICET |
| url |
http://hdl.handle.net/11336/48881 |
| identifier_str_mv |
Berrueta, Amanda Mabel; Hemingway Foday, Jennifer; Thorsten, Vanessa R.; Goldenberg, Robert L.; Carlo, Waldemar A.; et al.; Use of antenatal corticosteroids at health facilities and communities in low-and-middle income countries; BioMed Central; Reproductive Health; 13; 1; 5-2016; 1-6 1471-2458 CONICET Digital CONICET |
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eng |
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eng |
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info:eu-repo/semantics/altIdentifier/doi/10.1186/s12978-016-0176-2 info:eu-repo/semantics/altIdentifier/url/https://reproductive-health-journal.biomedcentral.com/articles/10.1186/s12978-016-0176-2 |
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info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
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BioMed Central |
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BioMed Central |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
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dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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