Estimation of effective population size using bivariate discrete distributions for modeling family size in beef cattle

Autores
Garrido, Lenin Ron; Birchmeier, Ana Nélida; Munilla Leguizamon, Sebastian; Cantet, Rodolfo Juan Carlos
Año de publicación
2008
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Pedigree records of 72,808 animals (45,668 females and 27,140 males) from the genetic evaluation program of the Argentine Brangus Association were used to estimate effective number of founders (Nf), effective number of ancestors (Na), and effective population size under random mating (Ne) or selection (NeS), in order to assess genetic variability. The average level of completeness of the pedigree was low (0.17) and the average level of inbreeding (F) calculated from the pedigree was equal to 0.24%. Animals in the reference population were 21,662 calves born from 2001 to 2005. The estimated measures of variability were Nf = 765.7 and Na = 387.5. The numbers of ancestors responsible for 100%, 50%, or 20% of the genes in the reference group, were equal to 12,471, 273, and 22, respectively. Direct estimates of Ne and NeS were calculated using the variances and covariances of family sizes, i.e. male and female progeny numbers for bulls and cows. Estimates of the dispersion parameters were from the Bivariate Poisson model for the cows, and from the Generalized Bivariate Negative Binomial (GBIVARNB) distribution for the bulls. The latter probability mass function accounted for overdispersion, a characteristic present in the sampling distribution of family size of bulls. The estimated variances of male and female progeny and the covariance between them for the bulls were 5.70, 271.28, and 30.15, respectively, and 1.15, 2.10, and 1.06 for the cows. Generation intervals (in years) were: sires of bulls = 5.0, sires of cows = 5.7, dams of bulls = 4.4, and dams of cows = 5.2. The estimated Ne was 274, which corresponds to a rate of inbreeding (F) of 0.18%, whereas NeS = 125 and F = 0.40%. As a check of the proposed methodology, all analyses were also performed using the pedigree records of 10,483 Angus animals from a herd with an average level of completeness of 0.68. Using the GBIVARNB model for both bulls and cows the estimated Ne = 95.4, thus F = 0.5% in perfect agreement with the calculated average inbreeding from pedigree records. Under selection, NeS = 79.3 and F = 0.6%. The larger difference between estimated Ne and NeS in the Brangus was related to the smaller bull to cow ratio in the breed. Therefore, it seems desirable to continue monitoring the effective size of the Argentine Brangus to prevent problems of inbreeding and lack of variability in the future. © 2007 Elsevier B.V. All rights reserved.
Fil: Garrido, Lenin Ron. Universidad de Las Fuerzas Armadas; Ecuador
Fil: Birchmeier, Ana Nélida. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal. Cátedra de Mejoramiento Genético Animal; Argentina
Fil: Munilla Leguizamon, Sebastian. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal. Cátedra de Mejoramiento Genético Animal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Cantet, Rodolfo Juan Carlos. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal. Cátedra de Mejoramiento Genético Animal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
BIVARIATE DISCRETE DISTRIBUTIONS
BRANGUS
EFFECTIVE POPULATION SIZE
FAMILY SIZE
OVERDISPERSION
SELECTION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/131614

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network_name_str CONICET Digital (CONICET)
spelling Estimation of effective population size using bivariate discrete distributions for modeling family size in beef cattleGarrido, Lenin RonBirchmeier, Ana NélidaMunilla Leguizamon, SebastianCantet, Rodolfo Juan CarlosBIVARIATE DISCRETE DISTRIBUTIONSBRANGUSEFFECTIVE POPULATION SIZEFAMILY SIZEOVERDISPERSIONSELECTIONhttps://purl.org/becyt/ford/4.2https://purl.org/becyt/ford/4Pedigree records of 72,808 animals (45,668 females and 27,140 males) from the genetic evaluation program of the Argentine Brangus Association were used to estimate effective number of founders (Nf), effective number of ancestors (Na), and effective population size under random mating (Ne) or selection (NeS), in order to assess genetic variability. The average level of completeness of the pedigree was low (0.17) and the average level of inbreeding (F) calculated from the pedigree was equal to 0.24%. Animals in the reference population were 21,662 calves born from 2001 to 2005. The estimated measures of variability were Nf = 765.7 and Na = 387.5. The numbers of ancestors responsible for 100%, 50%, or 20% of the genes in the reference group, were equal to 12,471, 273, and 22, respectively. Direct estimates of Ne and NeS were calculated using the variances and covariances of family sizes, i.e. male and female progeny numbers for bulls and cows. Estimates of the dispersion parameters were from the Bivariate Poisson model for the cows, and from the Generalized Bivariate Negative Binomial (GBIVARNB) distribution for the bulls. The latter probability mass function accounted for overdispersion, a characteristic present in the sampling distribution of family size of bulls. The estimated variances of male and female progeny and the covariance between them for the bulls were 5.70, 271.28, and 30.15, respectively, and 1.15, 2.10, and 1.06 for the cows. Generation intervals (in years) were: sires of bulls = 5.0, sires of cows = 5.7, dams of bulls = 4.4, and dams of cows = 5.2. The estimated Ne was 274, which corresponds to a rate of inbreeding (F) of 0.18%, whereas NeS = 125 and F = 0.40%. As a check of the proposed methodology, all analyses were also performed using the pedigree records of 10,483 Angus animals from a herd with an average level of completeness of 0.68. Using the GBIVARNB model for both bulls and cows the estimated Ne = 95.4, thus F = 0.5% in perfect agreement with the calculated average inbreeding from pedigree records. Under selection, NeS = 79.3 and F = 0.6%. The larger difference between estimated Ne and NeS in the Brangus was related to the smaller bull to cow ratio in the breed. Therefore, it seems desirable to continue monitoring the effective size of the Argentine Brangus to prevent problems of inbreeding and lack of variability in the future. © 2007 Elsevier B.V. All rights reserved.Fil: Garrido, Lenin Ron. Universidad de Las Fuerzas Armadas; EcuadorFil: Birchmeier, Ana Nélida. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal. Cátedra de Mejoramiento Genético Animal; ArgentinaFil: Munilla Leguizamon, Sebastian. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal. Cátedra de Mejoramiento Genético Animal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Cantet, Rodolfo Juan Carlos. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal. Cátedra de Mejoramiento Genético Animal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaElsevier Science2008-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/131614Garrido, Lenin Ron; Birchmeier, Ana Nélida; Munilla Leguizamon, Sebastian; Cantet, Rodolfo Juan Carlos; Estimation of effective population size using bivariate discrete distributions for modeling family size in beef cattle; Elsevier Science; Livestock Science; 117; 1; 8-2008; 43-511871-1413CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1871141307005380info:eu-repo/semantics/altIdentifier/doi/10.1016/j.livsci.2007.11.008info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:46:27Zoai:ri.conicet.gov.ar:11336/131614instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:46:27.64CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Estimation of effective population size using bivariate discrete distributions for modeling family size in beef cattle
title Estimation of effective population size using bivariate discrete distributions for modeling family size in beef cattle
spellingShingle Estimation of effective population size using bivariate discrete distributions for modeling family size in beef cattle
Garrido, Lenin Ron
BIVARIATE DISCRETE DISTRIBUTIONS
BRANGUS
EFFECTIVE POPULATION SIZE
FAMILY SIZE
OVERDISPERSION
SELECTION
title_short Estimation of effective population size using bivariate discrete distributions for modeling family size in beef cattle
title_full Estimation of effective population size using bivariate discrete distributions for modeling family size in beef cattle
title_fullStr Estimation of effective population size using bivariate discrete distributions for modeling family size in beef cattle
title_full_unstemmed Estimation of effective population size using bivariate discrete distributions for modeling family size in beef cattle
title_sort Estimation of effective population size using bivariate discrete distributions for modeling family size in beef cattle
dc.creator.none.fl_str_mv Garrido, Lenin Ron
Birchmeier, Ana Nélida
Munilla Leguizamon, Sebastian
Cantet, Rodolfo Juan Carlos
author Garrido, Lenin Ron
author_facet Garrido, Lenin Ron
Birchmeier, Ana Nélida
Munilla Leguizamon, Sebastian
Cantet, Rodolfo Juan Carlos
author_role author
author2 Birchmeier, Ana Nélida
Munilla Leguizamon, Sebastian
Cantet, Rodolfo Juan Carlos
author2_role author
author
author
dc.subject.none.fl_str_mv BIVARIATE DISCRETE DISTRIBUTIONS
BRANGUS
EFFECTIVE POPULATION SIZE
FAMILY SIZE
OVERDISPERSION
SELECTION
topic BIVARIATE DISCRETE DISTRIBUTIONS
BRANGUS
EFFECTIVE POPULATION SIZE
FAMILY SIZE
OVERDISPERSION
SELECTION
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.2
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv Pedigree records of 72,808 animals (45,668 females and 27,140 males) from the genetic evaluation program of the Argentine Brangus Association were used to estimate effective number of founders (Nf), effective number of ancestors (Na), and effective population size under random mating (Ne) or selection (NeS), in order to assess genetic variability. The average level of completeness of the pedigree was low (0.17) and the average level of inbreeding (F) calculated from the pedigree was equal to 0.24%. Animals in the reference population were 21,662 calves born from 2001 to 2005. The estimated measures of variability were Nf = 765.7 and Na = 387.5. The numbers of ancestors responsible for 100%, 50%, or 20% of the genes in the reference group, were equal to 12,471, 273, and 22, respectively. Direct estimates of Ne and NeS were calculated using the variances and covariances of family sizes, i.e. male and female progeny numbers for bulls and cows. Estimates of the dispersion parameters were from the Bivariate Poisson model for the cows, and from the Generalized Bivariate Negative Binomial (GBIVARNB) distribution for the bulls. The latter probability mass function accounted for overdispersion, a characteristic present in the sampling distribution of family size of bulls. The estimated variances of male and female progeny and the covariance between them for the bulls were 5.70, 271.28, and 30.15, respectively, and 1.15, 2.10, and 1.06 for the cows. Generation intervals (in years) were: sires of bulls = 5.0, sires of cows = 5.7, dams of bulls = 4.4, and dams of cows = 5.2. The estimated Ne was 274, which corresponds to a rate of inbreeding (F) of 0.18%, whereas NeS = 125 and F = 0.40%. As a check of the proposed methodology, all analyses were also performed using the pedigree records of 10,483 Angus animals from a herd with an average level of completeness of 0.68. Using the GBIVARNB model for both bulls and cows the estimated Ne = 95.4, thus F = 0.5% in perfect agreement with the calculated average inbreeding from pedigree records. Under selection, NeS = 79.3 and F = 0.6%. The larger difference between estimated Ne and NeS in the Brangus was related to the smaller bull to cow ratio in the breed. Therefore, it seems desirable to continue monitoring the effective size of the Argentine Brangus to prevent problems of inbreeding and lack of variability in the future. © 2007 Elsevier B.V. All rights reserved.
Fil: Garrido, Lenin Ron. Universidad de Las Fuerzas Armadas; Ecuador
Fil: Birchmeier, Ana Nélida. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal. Cátedra de Mejoramiento Genético Animal; Argentina
Fil: Munilla Leguizamon, Sebastian. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal. Cátedra de Mejoramiento Genético Animal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Cantet, Rodolfo Juan Carlos. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal. Cátedra de Mejoramiento Genético Animal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Pedigree records of 72,808 animals (45,668 females and 27,140 males) from the genetic evaluation program of the Argentine Brangus Association were used to estimate effective number of founders (Nf), effective number of ancestors (Na), and effective population size under random mating (Ne) or selection (NeS), in order to assess genetic variability. The average level of completeness of the pedigree was low (0.17) and the average level of inbreeding (F) calculated from the pedigree was equal to 0.24%. Animals in the reference population were 21,662 calves born from 2001 to 2005. The estimated measures of variability were Nf = 765.7 and Na = 387.5. The numbers of ancestors responsible for 100%, 50%, or 20% of the genes in the reference group, were equal to 12,471, 273, and 22, respectively. Direct estimates of Ne and NeS were calculated using the variances and covariances of family sizes, i.e. male and female progeny numbers for bulls and cows. Estimates of the dispersion parameters were from the Bivariate Poisson model for the cows, and from the Generalized Bivariate Negative Binomial (GBIVARNB) distribution for the bulls. The latter probability mass function accounted for overdispersion, a characteristic present in the sampling distribution of family size of bulls. The estimated variances of male and female progeny and the covariance between them for the bulls were 5.70, 271.28, and 30.15, respectively, and 1.15, 2.10, and 1.06 for the cows. Generation intervals (in years) were: sires of bulls = 5.0, sires of cows = 5.7, dams of bulls = 4.4, and dams of cows = 5.2. The estimated Ne was 274, which corresponds to a rate of inbreeding (F) of 0.18%, whereas NeS = 125 and F = 0.40%. As a check of the proposed methodology, all analyses were also performed using the pedigree records of 10,483 Angus animals from a herd with an average level of completeness of 0.68. Using the GBIVARNB model for both bulls and cows the estimated Ne = 95.4, thus F = 0.5% in perfect agreement with the calculated average inbreeding from pedigree records. Under selection, NeS = 79.3 and F = 0.6%. The larger difference between estimated Ne and NeS in the Brangus was related to the smaller bull to cow ratio in the breed. Therefore, it seems desirable to continue monitoring the effective size of the Argentine Brangus to prevent problems of inbreeding and lack of variability in the future. © 2007 Elsevier B.V. All rights reserved.
publishDate 2008
dc.date.none.fl_str_mv 2008-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/131614
Garrido, Lenin Ron; Birchmeier, Ana Nélida; Munilla Leguizamon, Sebastian; Cantet, Rodolfo Juan Carlos; Estimation of effective population size using bivariate discrete distributions for modeling family size in beef cattle; Elsevier Science; Livestock Science; 117; 1; 8-2008; 43-51
1871-1413
CONICET Digital
CONICET
url http://hdl.handle.net/11336/131614
identifier_str_mv Garrido, Lenin Ron; Birchmeier, Ana Nélida; Munilla Leguizamon, Sebastian; Cantet, Rodolfo Juan Carlos; Estimation of effective population size using bivariate discrete distributions for modeling family size in beef cattle; Elsevier Science; Livestock Science; 117; 1; 8-2008; 43-51
1871-1413
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1871141307005380
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.livsci.2007.11.008
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv application/pdf
application/pdf
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dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
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instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
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repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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