Metabolism of triacylglycerols in Rhodococcus species: insights from physiology and molecular genetics

Autores
Alvarez, Hector Manuel; Silva, Roxana Alejandra; Herrero, Marisa; Hernández, Martín Alejandro; Villalba, Maria
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Rhodococcus bacteria possess the ability to accumulate variable amounts of triacylglycerols (TAG) during growth on diverse carbon sources. The evolution seems to have selected these microorganisms as specialists in the accumulation of TAG among bacteria, since their biochemistry is efficiently designed for the biosynthesis and mobilization of these lipids. Detailed research of rhodococcal TAG metabolism started only a few years ago; thus, the fundamental understanding of this process and its regulation remains to be clarified. However, some interesting advances in the basic knowledge on TAG metabolism in rhodococci have been made. Most studies have focused on the physiology of TAG biosynthesis and mobilization in rhodococci. Only recently, some advances in molecular biology and genetics on TAG metabolism occurred as a result of the increasing available genomic information and the development of new genetic tools for rhodococci. These studies have been focused principally on some enzymes of TAG biosynthesis, such as the wax esters/diacylglycerolacyltransferases (WS/DGAT) and TAG granule-associated proteins. In this context, the most relevant achievements of basic research in the field have been summarized in this review article.
Fil: Alvarez, Hector Manuel. Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales - Sede Comodoro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; Argentina
Fil: Silva, Roxana Alejandra. Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales - Sede Comodoro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; Argentina
Fil: Herrero, Marisa. Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales - Sede Comodoro; Argentina
Fil: Hernández, Martín Alejandro. Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales - Sede Comodoro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; Argentina
Fil: Villalba, Maria. OIL M&S; . Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales - Sede Comodoro; Argentina
Materia
Rhodococcus
Triacylglycerols
Biosynthesis and degradation genes
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/5402
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Metabolism of triacylglycerols in Rhodococcus species: insights from physiology and molecular geneticsAlvarez, Hector ManuelSilva, Roxana AlejandraHerrero, MarisaHernández, Martín AlejandroVillalba, MariaRhodococcusTriacylglycerolsBiosynthesis and degradation geneshttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Rhodococcus bacteria possess the ability to accumulate variable amounts of triacylglycerols (TAG) during growth on diverse carbon sources. The evolution seems to have selected these microorganisms as specialists in the accumulation of TAG among bacteria, since their biochemistry is efficiently designed for the biosynthesis and mobilization of these lipids. Detailed research of rhodococcal TAG metabolism started only a few years ago; thus, the fundamental understanding of this process and its regulation remains to be clarified. However, some interesting advances in the basic knowledge on TAG metabolism in rhodococci have been made. Most studies have focused on the physiology of TAG biosynthesis and mobilization in rhodococci. Only recently, some advances in molecular biology and genetics on TAG metabolism occurred as a result of the increasing available genomic information and the development of new genetic tools for rhodococci. These studies have been focused principally on some enzymes of TAG biosynthesis, such as the wax esters/diacylglycerolacyltransferases (WS/DGAT) and TAG granule-associated proteins. In this context, the most relevant achievements of basic research in the field have been summarized in this review article.Fil: Alvarez, Hector Manuel. Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales - Sede Comodoro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; ArgentinaFil: Silva, Roxana Alejandra. Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales - Sede Comodoro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; ArgentinaFil: Herrero, Marisa. Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales - Sede Comodoro; ArgentinaFil: Hernández, Martín Alejandro. Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales - Sede Comodoro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; ArgentinaFil: Villalba, Maria. OIL M&S; . Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales - Sede Comodoro; ArgentinaLorem Ipsum Press2013-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/5402Alvarez, Hector Manuel; Silva, Roxana Alejandra; Herrero, Marisa; Hernández, Martín Alejandro; Villalba, Maria; Metabolism of triacylglycerols in Rhodococcus species: insights from physiology and molecular genetics; Lorem Ipsum Press; Journal of Molecular Biochemistry; 2; 2; 2-2013; 69-782241-0090enginfo:eu-repo/semantics/altIdentifier/url/http://www.jmolbiochem.com/index.php/JmolBiochem/article/view/89info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:30:48Zoai:ri.conicet.gov.ar:11336/5402instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:30:48.81CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Metabolism of triacylglycerols in Rhodococcus species: insights from physiology and molecular genetics
title Metabolism of triacylglycerols in Rhodococcus species: insights from physiology and molecular genetics
spellingShingle Metabolism of triacylglycerols in Rhodococcus species: insights from physiology and molecular genetics
Alvarez, Hector Manuel
Rhodococcus
Triacylglycerols
Biosynthesis and degradation genes
title_short Metabolism of triacylglycerols in Rhodococcus species: insights from physiology and molecular genetics
title_full Metabolism of triacylglycerols in Rhodococcus species: insights from physiology and molecular genetics
title_fullStr Metabolism of triacylglycerols in Rhodococcus species: insights from physiology and molecular genetics
title_full_unstemmed Metabolism of triacylglycerols in Rhodococcus species: insights from physiology and molecular genetics
title_sort Metabolism of triacylglycerols in Rhodococcus species: insights from physiology and molecular genetics
dc.creator.none.fl_str_mv Alvarez, Hector Manuel
Silva, Roxana Alejandra
Herrero, Marisa
Hernández, Martín Alejandro
Villalba, Maria
author Alvarez, Hector Manuel
author_facet Alvarez, Hector Manuel
Silva, Roxana Alejandra
Herrero, Marisa
Hernández, Martín Alejandro
Villalba, Maria
author_role author
author2 Silva, Roxana Alejandra
Herrero, Marisa
Hernández, Martín Alejandro
Villalba, Maria
author2_role author
author
author
author
dc.subject.none.fl_str_mv Rhodococcus
Triacylglycerols
Biosynthesis and degradation genes
topic Rhodococcus
Triacylglycerols
Biosynthesis and degradation genes
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Rhodococcus bacteria possess the ability to accumulate variable amounts of triacylglycerols (TAG) during growth on diverse carbon sources. The evolution seems to have selected these microorganisms as specialists in the accumulation of TAG among bacteria, since their biochemistry is efficiently designed for the biosynthesis and mobilization of these lipids. Detailed research of rhodococcal TAG metabolism started only a few years ago; thus, the fundamental understanding of this process and its regulation remains to be clarified. However, some interesting advances in the basic knowledge on TAG metabolism in rhodococci have been made. Most studies have focused on the physiology of TAG biosynthesis and mobilization in rhodococci. Only recently, some advances in molecular biology and genetics on TAG metabolism occurred as a result of the increasing available genomic information and the development of new genetic tools for rhodococci. These studies have been focused principally on some enzymes of TAG biosynthesis, such as the wax esters/diacylglycerolacyltransferases (WS/DGAT) and TAG granule-associated proteins. In this context, the most relevant achievements of basic research in the field have been summarized in this review article.
Fil: Alvarez, Hector Manuel. Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales - Sede Comodoro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; Argentina
Fil: Silva, Roxana Alejandra. Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales - Sede Comodoro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; Argentina
Fil: Herrero, Marisa. Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales - Sede Comodoro; Argentina
Fil: Hernández, Martín Alejandro. Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales - Sede Comodoro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; Argentina
Fil: Villalba, Maria. OIL M&S; . Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales - Sede Comodoro; Argentina
description Rhodococcus bacteria possess the ability to accumulate variable amounts of triacylglycerols (TAG) during growth on diverse carbon sources. The evolution seems to have selected these microorganisms as specialists in the accumulation of TAG among bacteria, since their biochemistry is efficiently designed for the biosynthesis and mobilization of these lipids. Detailed research of rhodococcal TAG metabolism started only a few years ago; thus, the fundamental understanding of this process and its regulation remains to be clarified. However, some interesting advances in the basic knowledge on TAG metabolism in rhodococci have been made. Most studies have focused on the physiology of TAG biosynthesis and mobilization in rhodococci. Only recently, some advances in molecular biology and genetics on TAG metabolism occurred as a result of the increasing available genomic information and the development of new genetic tools for rhodococci. These studies have been focused principally on some enzymes of TAG biosynthesis, such as the wax esters/diacylglycerolacyltransferases (WS/DGAT) and TAG granule-associated proteins. In this context, the most relevant achievements of basic research in the field have been summarized in this review article.
publishDate 2013
dc.date.none.fl_str_mv 2013-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/5402
Alvarez, Hector Manuel; Silva, Roxana Alejandra; Herrero, Marisa; Hernández, Martín Alejandro; Villalba, Maria; Metabolism of triacylglycerols in Rhodococcus species: insights from physiology and molecular genetics; Lorem Ipsum Press; Journal of Molecular Biochemistry; 2; 2; 2-2013; 69-78
2241-0090
url http://hdl.handle.net/11336/5402
identifier_str_mv Alvarez, Hector Manuel; Silva, Roxana Alejandra; Herrero, Marisa; Hernández, Martín Alejandro; Villalba, Maria; Metabolism of triacylglycerols in Rhodococcus species: insights from physiology and molecular genetics; Lorem Ipsum Press; Journal of Molecular Biochemistry; 2; 2; 2-2013; 69-78
2241-0090
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.jmolbiochem.com/index.php/JmolBiochem/article/view/89
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Lorem Ipsum Press
publisher.none.fl_str_mv Lorem Ipsum Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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