Challenges in electrochemical aptasensors and current sensing architectures using flat gold surfaces

Autores
Rozenblum, Tomas Guido; Pollitzer, Iván Gustavo; Radrizzani Helguera, Martin
Año de publicación
2019
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In recent years, reagentless aptamer biosensors, named aptasensors, have shown significant advancements. Particularly, electrochemical aptasensors could change the field of biosensors in this era, where digitalization seems to be a common goal of many fields. Biomedical devices are integrating electronic technologies for detecting pathogens, biomolecules, small molecules, and ions, and the physical-chemical properties of nucleic acid aptamers makes them very interesting for these devices. Aptamers can be easily synthesized and functionalized with functional groups for immobilization and with redox chemical groups that allow for the conversion of molecular interactions into electrical signals. Furthermore, non-labeled aptamers have also been utilized. This review presents the current challenges involved in aptasensor architectures based on gold electrodes as transducers.
Fil: Rozenblum, Tomas Guido. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Argentina de la Empresa; Argentina
Fil: Pollitzer, Iván Gustavo. Aplife Biotech S. A.; Argentina
Fil: Radrizzani Helguera, Martin. Universidad Nacional de San Martín. Escuela de Ciencia y Tecnología. Laboratorio de Neuroingeniería; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
APTAMERS
APTASENSOR
APTASENSORDESIGNS
ARCHITECTURES
BIOSENSORS
COMBINATORIAL CHEMISTRY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/159539
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Challenges in electrochemical aptasensors and current sensing architectures using flat gold surfacesRozenblum, Tomas GuidoPollitzer, Iván GustavoRadrizzani Helguera, MartinAPTAMERSAPTASENSORAPTASENSORDESIGNSARCHITECTURESBIOSENSORSCOMBINATORIAL CHEMISTRYhttps://purl.org/becyt/ford/2.10https://purl.org/becyt/ford/2In recent years, reagentless aptamer biosensors, named aptasensors, have shown significant advancements. Particularly, electrochemical aptasensors could change the field of biosensors in this era, where digitalization seems to be a common goal of many fields. Biomedical devices are integrating electronic technologies for detecting pathogens, biomolecules, small molecules, and ions, and the physical-chemical properties of nucleic acid aptamers makes them very interesting for these devices. Aptamers can be easily synthesized and functionalized with functional groups for immobilization and with redox chemical groups that allow for the conversion of molecular interactions into electrical signals. Furthermore, non-labeled aptamers have also been utilized. This review presents the current challenges involved in aptasensor architectures based on gold electrodes as transducers.Fil: Rozenblum, Tomas Guido. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Argentina de la Empresa; ArgentinaFil: Pollitzer, Iván Gustavo. Aplife Biotech S. A.; ArgentinaFil: Radrizzani Helguera, Martin. Universidad Nacional de San Martín. Escuela de Ciencia y Tecnología. Laboratorio de Neuroingeniería; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaMPDI2019-11-13info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/159539Rozenblum, Tomas Guido; Pollitzer, Iván Gustavo; Radrizzani Helguera, Martin; Challenges in electrochemical aptasensors and current sensing architectures using flat gold surfaces; MPDI; Chemosensors; 7; 4; 13-11-2019; 1-142227-9040CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2227-9040/7/4/57info:eu-repo/semantics/altIdentifier/doi/10.3390/chemosensors7040057info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:22:42Zoai:ri.conicet.gov.ar:11336/159539instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:22:43.124CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Challenges in electrochemical aptasensors and current sensing architectures using flat gold surfaces
title Challenges in electrochemical aptasensors and current sensing architectures using flat gold surfaces
spellingShingle Challenges in electrochemical aptasensors and current sensing architectures using flat gold surfaces
Rozenblum, Tomas Guido
APTAMERS
APTASENSOR
APTASENSORDESIGNS
ARCHITECTURES
BIOSENSORS
COMBINATORIAL CHEMISTRY
title_short Challenges in electrochemical aptasensors and current sensing architectures using flat gold surfaces
title_full Challenges in electrochemical aptasensors and current sensing architectures using flat gold surfaces
title_fullStr Challenges in electrochemical aptasensors and current sensing architectures using flat gold surfaces
title_full_unstemmed Challenges in electrochemical aptasensors and current sensing architectures using flat gold surfaces
title_sort Challenges in electrochemical aptasensors and current sensing architectures using flat gold surfaces
dc.creator.none.fl_str_mv Rozenblum, Tomas Guido
Pollitzer, Iván Gustavo
Radrizzani Helguera, Martin
author Rozenblum, Tomas Guido
author_facet Rozenblum, Tomas Guido
Pollitzer, Iván Gustavo
Radrizzani Helguera, Martin
author_role author
author2 Pollitzer, Iván Gustavo
Radrizzani Helguera, Martin
author2_role author
author
dc.subject.none.fl_str_mv APTAMERS
APTASENSOR
APTASENSORDESIGNS
ARCHITECTURES
BIOSENSORS
COMBINATORIAL CHEMISTRY
topic APTAMERS
APTASENSOR
APTASENSORDESIGNS
ARCHITECTURES
BIOSENSORS
COMBINATORIAL CHEMISTRY
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.10
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv In recent years, reagentless aptamer biosensors, named aptasensors, have shown significant advancements. Particularly, electrochemical aptasensors could change the field of biosensors in this era, where digitalization seems to be a common goal of many fields. Biomedical devices are integrating electronic technologies for detecting pathogens, biomolecules, small molecules, and ions, and the physical-chemical properties of nucleic acid aptamers makes them very interesting for these devices. Aptamers can be easily synthesized and functionalized with functional groups for immobilization and with redox chemical groups that allow for the conversion of molecular interactions into electrical signals. Furthermore, non-labeled aptamers have also been utilized. This review presents the current challenges involved in aptasensor architectures based on gold electrodes as transducers.
Fil: Rozenblum, Tomas Guido. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Argentina de la Empresa; Argentina
Fil: Pollitzer, Iván Gustavo. Aplife Biotech S. A.; Argentina
Fil: Radrizzani Helguera, Martin. Universidad Nacional de San Martín. Escuela de Ciencia y Tecnología. Laboratorio de Neuroingeniería; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description In recent years, reagentless aptamer biosensors, named aptasensors, have shown significant advancements. Particularly, electrochemical aptasensors could change the field of biosensors in this era, where digitalization seems to be a common goal of many fields. Biomedical devices are integrating electronic technologies for detecting pathogens, biomolecules, small molecules, and ions, and the physical-chemical properties of nucleic acid aptamers makes them very interesting for these devices. Aptamers can be easily synthesized and functionalized with functional groups for immobilization and with redox chemical groups that allow for the conversion of molecular interactions into electrical signals. Furthermore, non-labeled aptamers have also been utilized. This review presents the current challenges involved in aptasensor architectures based on gold electrodes as transducers.
publishDate 2019
dc.date.none.fl_str_mv 2019-11-13
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/159539
Rozenblum, Tomas Guido; Pollitzer, Iván Gustavo; Radrizzani Helguera, Martin; Challenges in electrochemical aptasensors and current sensing architectures using flat gold surfaces; MPDI; Chemosensors; 7; 4; 13-11-2019; 1-14
2227-9040
CONICET Digital
CONICET
url http://hdl.handle.net/11336/159539
identifier_str_mv Rozenblum, Tomas Guido; Pollitzer, Iván Gustavo; Radrizzani Helguera, Martin; Challenges in electrochemical aptasensors and current sensing architectures using flat gold surfaces; MPDI; Chemosensors; 7; 4; 13-11-2019; 1-14
2227-9040
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2227-9040/7/4/57
info:eu-repo/semantics/altIdentifier/doi/10.3390/chemosensors7040057
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv MPDI
publisher.none.fl_str_mv MPDI
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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