Epidemiology of snakebite and use of antivenom in Argentina

Autores
Dolab, Jorge Adrian; de Roodt, Adolfo Rafael; de Titto, Ernesto Horacio; García, Susana Isabel; Funes, Raúl; Salomón, Oscar Daniel; Chippaux, Jean Philippe
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A total of 8083 completed questionnaires was collected between 1978 and 1998. The annual incidence of snakebite was 1.8 bites per 100 000 inhabitants, with a high geographical heterogeneity; in the northern provinces of the country, the incidence can exceed 150 snakebites per 100 000 people per year. Bothrops (pit viper) bites predominated, accounting for 96.6% (6720/6957) of envenomations, bites from Crotalus (rattlesnake) accounted for 2.8% (195/6957), and bites from Micrurus (coral snake) for 0.6% (42/6957). Most patients were young men, who were generally bitten during agricultural activities, i.e. while working in the fields. Most snakebites (78.9%, 5852/7419) were to the lower limb, including 58.3% (4322/7419) to the foot. The case fatality rate was <0.04% (3/8083). Most envenomations (90%, 7275/8083) were treated with specific antivenom during the first 4 h after the bite. The median dose of antivenom was two vials for viper bites (Bothrops and Crotalus) and three vials for Micrurus bites. Conclusion These preliminary results should enable manufacturers to increase the availability of appropriate antivenom and health authorities to improve the management of snakebites where they are most common.
Fil: Dolab, Jorge Adrian. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud; Argentina
Fil: de Roodt, Adolfo Rafael. Universidad de Buenos Aires; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; Argentina
Fil: de Titto, Ernesto Horacio. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: García, Susana Isabel. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud; Argentina
Fil: Funes, Raúl. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud; Argentina
Fil: Salomón, Oscar Daniel. Ministerio de Salud. Instituto Nacional de Medicina Tropical; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Chippaux, Jean Philippe. Université Paris Descartes; Francia
Materia
Antivenom
Argentina
Bothrops
Crotalus
Micrurus
Snakebite
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/29763
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/29763
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Epidemiology of snakebite and use of antivenom in ArgentinaDolab, Jorge Adriande Roodt, Adolfo Rafaelde Titto, Ernesto HoracioGarcía, Susana IsabelFunes, RaúlSalomón, Oscar DanielChippaux, Jean PhilippeAntivenomArgentinaBothropsCrotalusMicrurusSnakebitehttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3A total of 8083 completed questionnaires was collected between 1978 and 1998. The annual incidence of snakebite was 1.8 bites per 100 000 inhabitants, with a high geographical heterogeneity; in the northern provinces of the country, the incidence can exceed 150 snakebites per 100 000 people per year. Bothrops (pit viper) bites predominated, accounting for 96.6% (6720/6957) of envenomations, bites from Crotalus (rattlesnake) accounted for 2.8% (195/6957), and bites from Micrurus (coral snake) for 0.6% (42/6957). Most patients were young men, who were generally bitten during agricultural activities, i.e. while working in the fields. Most snakebites (78.9%, 5852/7419) were to the lower limb, including 58.3% (4322/7419) to the foot. The case fatality rate was <0.04% (3/8083). Most envenomations (90%, 7275/8083) were treated with specific antivenom during the first 4 h after the bite. The median dose of antivenom was two vials for viper bites (Bothrops and Crotalus) and three vials for Micrurus bites. Conclusion These preliminary results should enable manufacturers to increase the availability of appropriate antivenom and health authorities to improve the management of snakebites where they are most common.Fil: Dolab, Jorge Adrian. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud; ArgentinaFil: de Roodt, Adolfo Rafael. Universidad de Buenos Aires; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; ArgentinaFil: de Titto, Ernesto Horacio. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: García, Susana Isabel. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud; ArgentinaFil: Funes, Raúl. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud; ArgentinaFil: Salomón, Oscar Daniel. Ministerio de Salud. Instituto Nacional de Medicina Tropical; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Chippaux, Jean Philippe. Université Paris Descartes; FranciaOxford University Press2014-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/29763Dolab, Jorge Adrian; de Roodt, Adolfo Rafael; de Titto, Ernesto Horacio; García, Susana Isabel; Funes, Raúl; et al.; Epidemiology of snakebite and use of antivenom in Argentina; Oxford University Press; Transactions of the Royal Society of Tropical Medicine and Hygiene; 108; 5; 3-2014; 269-2760035-92031878-3503CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1093/trstmh/tru038info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/trstmh/article-abstract/108/5/269/1933985info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:22:24Zoai:ri.conicet.gov.ar:11336/29763instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:22:24.772CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Epidemiology of snakebite and use of antivenom in Argentina
title Epidemiology of snakebite and use of antivenom in Argentina
spellingShingle Epidemiology of snakebite and use of antivenom in Argentina
Dolab, Jorge Adrian
Antivenom
Argentina
Bothrops
Crotalus
Micrurus
Snakebite
title_short Epidemiology of snakebite and use of antivenom in Argentina
title_full Epidemiology of snakebite and use of antivenom in Argentina
title_fullStr Epidemiology of snakebite and use of antivenom in Argentina
title_full_unstemmed Epidemiology of snakebite and use of antivenom in Argentina
title_sort Epidemiology of snakebite and use of antivenom in Argentina
dc.creator.none.fl_str_mv Dolab, Jorge Adrian
de Roodt, Adolfo Rafael
de Titto, Ernesto Horacio
García, Susana Isabel
Funes, Raúl
Salomón, Oscar Daniel
Chippaux, Jean Philippe
author Dolab, Jorge Adrian
author_facet Dolab, Jorge Adrian
de Roodt, Adolfo Rafael
de Titto, Ernesto Horacio
García, Susana Isabel
Funes, Raúl
Salomón, Oscar Daniel
Chippaux, Jean Philippe
author_role author
author2 de Roodt, Adolfo Rafael
de Titto, Ernesto Horacio
García, Susana Isabel
Funes, Raúl
Salomón, Oscar Daniel
Chippaux, Jean Philippe
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Antivenom
Argentina
Bothrops
Crotalus
Micrurus
Snakebite
topic Antivenom
Argentina
Bothrops
Crotalus
Micrurus
Snakebite
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv A total of 8083 completed questionnaires was collected between 1978 and 1998. The annual incidence of snakebite was 1.8 bites per 100 000 inhabitants, with a high geographical heterogeneity; in the northern provinces of the country, the incidence can exceed 150 snakebites per 100 000 people per year. Bothrops (pit viper) bites predominated, accounting for 96.6% (6720/6957) of envenomations, bites from Crotalus (rattlesnake) accounted for 2.8% (195/6957), and bites from Micrurus (coral snake) for 0.6% (42/6957). Most patients were young men, who were generally bitten during agricultural activities, i.e. while working in the fields. Most snakebites (78.9%, 5852/7419) were to the lower limb, including 58.3% (4322/7419) to the foot. The case fatality rate was <0.04% (3/8083). Most envenomations (90%, 7275/8083) were treated with specific antivenom during the first 4 h after the bite. The median dose of antivenom was two vials for viper bites (Bothrops and Crotalus) and three vials for Micrurus bites. Conclusion These preliminary results should enable manufacturers to increase the availability of appropriate antivenom and health authorities to improve the management of snakebites where they are most common.
Fil: Dolab, Jorge Adrian. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud; Argentina
Fil: de Roodt, Adolfo Rafael. Universidad de Buenos Aires; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; Argentina
Fil: de Titto, Ernesto Horacio. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: García, Susana Isabel. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud; Argentina
Fil: Funes, Raúl. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud; Argentina
Fil: Salomón, Oscar Daniel. Ministerio de Salud. Instituto Nacional de Medicina Tropical; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Chippaux, Jean Philippe. Université Paris Descartes; Francia
description A total of 8083 completed questionnaires was collected between 1978 and 1998. The annual incidence of snakebite was 1.8 bites per 100 000 inhabitants, with a high geographical heterogeneity; in the northern provinces of the country, the incidence can exceed 150 snakebites per 100 000 people per year. Bothrops (pit viper) bites predominated, accounting for 96.6% (6720/6957) of envenomations, bites from Crotalus (rattlesnake) accounted for 2.8% (195/6957), and bites from Micrurus (coral snake) for 0.6% (42/6957). Most patients were young men, who were generally bitten during agricultural activities, i.e. while working in the fields. Most snakebites (78.9%, 5852/7419) were to the lower limb, including 58.3% (4322/7419) to the foot. The case fatality rate was <0.04% (3/8083). Most envenomations (90%, 7275/8083) were treated with specific antivenom during the first 4 h after the bite. The median dose of antivenom was two vials for viper bites (Bothrops and Crotalus) and three vials for Micrurus bites. Conclusion These preliminary results should enable manufacturers to increase the availability of appropriate antivenom and health authorities to improve the management of snakebites where they are most common.
publishDate 2014
dc.date.none.fl_str_mv 2014-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/29763
Dolab, Jorge Adrian; de Roodt, Adolfo Rafael; de Titto, Ernesto Horacio; García, Susana Isabel; Funes, Raúl; et al.; Epidemiology of snakebite and use of antivenom in Argentina; Oxford University Press; Transactions of the Royal Society of Tropical Medicine and Hygiene; 108; 5; 3-2014; 269-276
0035-9203
1878-3503
CONICET Digital
CONICET
url http://hdl.handle.net/11336/29763
identifier_str_mv Dolab, Jorge Adrian; de Roodt, Adolfo Rafael; de Titto, Ernesto Horacio; García, Susana Isabel; Funes, Raúl; et al.; Epidemiology of snakebite and use of antivenom in Argentina; Oxford University Press; Transactions of the Royal Society of Tropical Medicine and Hygiene; 108; 5; 3-2014; 269-276
0035-9203
1878-3503
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1093/trstmh/tru038
info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/trstmh/article-abstract/108/5/269/1933985
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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