Study on partition and release of molecules in superabsorbent thermosensitive nanocomposites

Autores
Molina, María Alejandra; Rivarola, Claudia Rosana; Barbero, César Alfredo
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Nanocomposites are synthesized by in-situ polymerization of conducting polymers: polyaniline (PANI) or poly(N-methylaniline) (PNMANI) inside thermosensitive hydrogels based on poly(N-isopropylacrylamide) (PNIPAM) homopolymer and copolymers with 2-acrylamido-2-methyl propane sulfonic acid (AMPS). Large swelling capacities (up to 25,000%) are measured for a nanocomposite based on a hydrogel containing only 2% of anionic monomer units. Dynamic swelling experiences show that water intake follows a non-Fickian mechanism. Drug release kinetics and partition coefficients (K)of model compounds (Methyl Orange, Ruthenium-tris(2,20-bipyridyl) ion, Dansyl Chloride) and pharmaceuticals (Tryptophan, Propranolol Chloride, Riboflavin) were measured. Log K values were determined by UVevisible or fluorescence spectroscopy, below and above the phase transition temperature of the materials. Large values of log K (>3) were measured for tryptophan while the same material shows small log K (1.5) for riboflavin. Depending on the nanocomposite/solute interactions, the partition increases ordecreases upon phase transition. Several nanocomposites studied show potential for application in the separation of solutes or water purification. Additionally, it is possible to synthesize  nanocomposites which show different partition coefficients for the same molecule. In that way, a specific pattern could be measured for each molecule allowing its identification.
Fil: Molina, María Alejandra. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Rivarola, Claudia Rosana. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Barbero, César Alfredo. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Materia
SUPERABSORBENT
THERMOSENSITIVE
PARTITION COEFFICIENT
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/269022
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Study on partition and release of molecules in superabsorbent thermosensitive nanocompositesMolina, María AlejandraRivarola, Claudia RosanaBarbero, César AlfredoSUPERABSORBENTTHERMOSENSITIVEPARTITION COEFFICIENThttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Nanocomposites are synthesized by in-situ polymerization of conducting polymers: polyaniline (PANI) or poly(N-methylaniline) (PNMANI) inside thermosensitive hydrogels based on poly(N-isopropylacrylamide) (PNIPAM) homopolymer and copolymers with 2-acrylamido-2-methyl propane sulfonic acid (AMPS). Large swelling capacities (up to 25,000%) are measured for a nanocomposite based on a hydrogel containing only 2% of anionic monomer units. Dynamic swelling experiences show that water intake follows a non-Fickian mechanism. Drug release kinetics and partition coefficients (K)of model compounds (Methyl Orange, Ruthenium-tris(2,20-bipyridyl) ion, Dansyl Chloride) and pharmaceuticals (Tryptophan, Propranolol Chloride, Riboflavin) were measured. Log K values were determined by UVevisible or fluorescence spectroscopy, below and above the phase transition temperature of the materials. Large values of log K (>3) were measured for tryptophan while the same material shows small log K (1.5) for riboflavin. Depending on the nanocomposite/solute interactions, the partition increases ordecreases upon phase transition. Several nanocomposites studied show potential for application in the separation of solutes or water purification. Additionally, it is possible to synthesize  nanocomposites which show different partition coefficients for the same molecule. In that way, a specific pattern could be measured for each molecule allowing its identification.Fil: Molina, María Alejandra. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Rivarola, Claudia Rosana. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Barbero, César Alfredo. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaElsevier2012-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/269022Molina, María Alejandra; Rivarola, Claudia Rosana; Barbero, César Alfredo; Study on partition and release of molecules in superabsorbent thermosensitive nanocomposites; Elsevier; Polymer; 53; 2; 1-2012; 445-4530032-3861CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.polymer.2011.11.037info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:00:20Zoai:ri.conicet.gov.ar:11336/269022instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:00:20.712CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Study on partition and release of molecules in superabsorbent thermosensitive nanocomposites
title Study on partition and release of molecules in superabsorbent thermosensitive nanocomposites
spellingShingle Study on partition and release of molecules in superabsorbent thermosensitive nanocomposites
Molina, María Alejandra
SUPERABSORBENT
THERMOSENSITIVE
PARTITION COEFFICIENT
title_short Study on partition and release of molecules in superabsorbent thermosensitive nanocomposites
title_full Study on partition and release of molecules in superabsorbent thermosensitive nanocomposites
title_fullStr Study on partition and release of molecules in superabsorbent thermosensitive nanocomposites
title_full_unstemmed Study on partition and release of molecules in superabsorbent thermosensitive nanocomposites
title_sort Study on partition and release of molecules in superabsorbent thermosensitive nanocomposites
dc.creator.none.fl_str_mv Molina, María Alejandra
Rivarola, Claudia Rosana
Barbero, César Alfredo
author Molina, María Alejandra
author_facet Molina, María Alejandra
Rivarola, Claudia Rosana
Barbero, César Alfredo
author_role author
author2 Rivarola, Claudia Rosana
Barbero, César Alfredo
author2_role author
author
dc.subject.none.fl_str_mv SUPERABSORBENT
THERMOSENSITIVE
PARTITION COEFFICIENT
topic SUPERABSORBENT
THERMOSENSITIVE
PARTITION COEFFICIENT
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Nanocomposites are synthesized by in-situ polymerization of conducting polymers: polyaniline (PANI) or poly(N-methylaniline) (PNMANI) inside thermosensitive hydrogels based on poly(N-isopropylacrylamide) (PNIPAM) homopolymer and copolymers with 2-acrylamido-2-methyl propane sulfonic acid (AMPS). Large swelling capacities (up to 25,000%) are measured for a nanocomposite based on a hydrogel containing only 2% of anionic monomer units. Dynamic swelling experiences show that water intake follows a non-Fickian mechanism. Drug release kinetics and partition coefficients (K)of model compounds (Methyl Orange, Ruthenium-tris(2,20-bipyridyl) ion, Dansyl Chloride) and pharmaceuticals (Tryptophan, Propranolol Chloride, Riboflavin) were measured. Log K values were determined by UVevisible or fluorescence spectroscopy, below and above the phase transition temperature of the materials. Large values of log K (>3) were measured for tryptophan while the same material shows small log K (1.5) for riboflavin. Depending on the nanocomposite/solute interactions, the partition increases ordecreases upon phase transition. Several nanocomposites studied show potential for application in the separation of solutes or water purification. Additionally, it is possible to synthesize  nanocomposites which show different partition coefficients for the same molecule. In that way, a specific pattern could be measured for each molecule allowing its identification.
Fil: Molina, María Alejandra. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Rivarola, Claudia Rosana. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Barbero, César Alfredo. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
description Nanocomposites are synthesized by in-situ polymerization of conducting polymers: polyaniline (PANI) or poly(N-methylaniline) (PNMANI) inside thermosensitive hydrogels based on poly(N-isopropylacrylamide) (PNIPAM) homopolymer and copolymers with 2-acrylamido-2-methyl propane sulfonic acid (AMPS). Large swelling capacities (up to 25,000%) are measured for a nanocomposite based on a hydrogel containing only 2% of anionic monomer units. Dynamic swelling experiences show that water intake follows a non-Fickian mechanism. Drug release kinetics and partition coefficients (K)of model compounds (Methyl Orange, Ruthenium-tris(2,20-bipyridyl) ion, Dansyl Chloride) and pharmaceuticals (Tryptophan, Propranolol Chloride, Riboflavin) were measured. Log K values were determined by UVevisible or fluorescence spectroscopy, below and above the phase transition temperature of the materials. Large values of log K (>3) were measured for tryptophan while the same material shows small log K (1.5) for riboflavin. Depending on the nanocomposite/solute interactions, the partition increases ordecreases upon phase transition. Several nanocomposites studied show potential for application in the separation of solutes or water purification. Additionally, it is possible to synthesize  nanocomposites which show different partition coefficients for the same molecule. In that way, a specific pattern could be measured for each molecule allowing its identification.
publishDate 2012
dc.date.none.fl_str_mv 2012-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/269022
Molina, María Alejandra; Rivarola, Claudia Rosana; Barbero, César Alfredo; Study on partition and release of molecules in superabsorbent thermosensitive nanocomposites; Elsevier; Polymer; 53; 2; 1-2012; 445-453
0032-3861
CONICET Digital
CONICET
url http://hdl.handle.net/11336/269022
identifier_str_mv Molina, María Alejandra; Rivarola, Claudia Rosana; Barbero, César Alfredo; Study on partition and release of molecules in superabsorbent thermosensitive nanocomposites; Elsevier; Polymer; 53; 2; 1-2012; 445-453
0032-3861
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.polymer.2011.11.037
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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