Effect of Furans and a Pyran on Several Quorum Sensing Factors in Ralstonia solanacearum

Autores
Gallego Cruz, Adriana María; Giordano, Walter Fabian; Rosero, Esteban; Echeverri, Fernando
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Ralstonia solanacearum race 2 is the causative agent of Bacterial Wilt in bananas, a disease also known as Moko disease. Once this bacterium becomes established within a plant, it causes the death of its host. Currently, no treatment is available for Bacterial Wilt, and the disease is able to destroy 100% of the crops in afflicted áreas.This study investigates a non-biocidal control method for R. solanacearum that attempts to nullify the pathogenic effects of R. solanacearum by interfering with the bacteria?s Quorum Sensing (QS) communication system. The effects of several molecules on R. solanacearum growth, biofilm formation and production of acylated homoserine lactone (AHL) autoinducers were analyzed. The results suggested that, of the molecules tested, 5,6 dihydro-2(H)- pyran-2-one most effectively inhibited growth, biofilm formation and AHL production. Furfural, 3-methyl-2(5H)- furanone and methyl 2-furoate also effectively inhibited growth. These molecules affected biofilm formation in a concentration-dependent manner. In addition, 3-methyl-2(5H)-furanone and methyl 2-furoate likewise inhibited AHL production. Therefore, all of these molecules could be useful for controlling R. solanacearum.
Fil: Gallego Cruz, Adriana María. Universidad de Antioquia; Colombia
Fil: Giordano, Walter Fabian. Universidad Nacional de Rio Cuarto. Facultad de Cs.exactas Fisicoquimicas y Naturales. Instituto de Biotecnologia Ambiental y Salud. - Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Cordoba. Instituto de Biotecnologia Ambiental y Salud.; Argentina
Fil: Rosero, Esteban. Universidad de Antioquia; Colombia
Fil: Echeverri, Fernando. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; Argentina
Materia
FURAN
PYRAN
QUORUM SENSING
RALSTONIA
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/107500
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/107500
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Effect of Furans and a Pyran on Several Quorum Sensing Factors in Ralstonia solanacearumGallego Cruz, Adriana MaríaGiordano, Walter FabianRosero, EstebanEcheverri, FernandoFURANPYRANQUORUM SENSINGRALSTONIAhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Ralstonia solanacearum race 2 is the causative agent of Bacterial Wilt in bananas, a disease also known as Moko disease. Once this bacterium becomes established within a plant, it causes the death of its host. Currently, no treatment is available for Bacterial Wilt, and the disease is able to destroy 100% of the crops in afflicted áreas.This study investigates a non-biocidal control method for R. solanacearum that attempts to nullify the pathogenic effects of R. solanacearum by interfering with the bacteria?s Quorum Sensing (QS) communication system. The effects of several molecules on R. solanacearum growth, biofilm formation and production of acylated homoserine lactone (AHL) autoinducers were analyzed. The results suggested that, of the molecules tested, 5,6 dihydro-2(H)- pyran-2-one most effectively inhibited growth, biofilm formation and AHL production. Furfural, 3-methyl-2(5H)- furanone and methyl 2-furoate also effectively inhibited growth. These molecules affected biofilm formation in a concentration-dependent manner. In addition, 3-methyl-2(5H)-furanone and methyl 2-furoate likewise inhibited AHL production. Therefore, all of these molecules could be useful for controlling R. solanacearum.Fil: Gallego Cruz, Adriana María. Universidad de Antioquia; ColombiaFil: Giordano, Walter Fabian. Universidad Nacional de Rio Cuarto. Facultad de Cs.exactas Fisicoquimicas y Naturales. Instituto de Biotecnologia Ambiental y Salud. - Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Cordoba. Instituto de Biotecnologia Ambiental y Salud.; ArgentinaFil: Rosero, Esteban. Universidad de Antioquia; ColombiaFil: Echeverri, Fernando. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; ArgentinaOMICS International2016-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/107500Gallego Cruz, Adriana María; Giordano, Walter Fabian; Rosero, Esteban; Echeverri, Fernando; Effect of Furans and a Pyran on Several Quorum Sensing Factors in Ralstonia solanacearum; OMICS International; Journal of oJ Microbial & Biochemical Technology; 08; 06; 11-2016; 478-4821948-5948CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.omicsonline.org/open-access/effect-of-furans-and-a-pyran-on-several-quorum-sensing-factors-inralstonia-solanacearum-1948-5948-1000328.php?aid=83726info:eu-repo/semantics/altIdentifier/doi/10.4172/1948-5948.1000328info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:42:22Zoai:ri.conicet.gov.ar:11336/107500instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:42:23.092CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Effect of Furans and a Pyran on Several Quorum Sensing Factors in Ralstonia solanacearum
title Effect of Furans and a Pyran on Several Quorum Sensing Factors in Ralstonia solanacearum
spellingShingle Effect of Furans and a Pyran on Several Quorum Sensing Factors in Ralstonia solanacearum
Gallego Cruz, Adriana María
FURAN
PYRAN
QUORUM SENSING
RALSTONIA
title_short Effect of Furans and a Pyran on Several Quorum Sensing Factors in Ralstonia solanacearum
title_full Effect of Furans and a Pyran on Several Quorum Sensing Factors in Ralstonia solanacearum
title_fullStr Effect of Furans and a Pyran on Several Quorum Sensing Factors in Ralstonia solanacearum
title_full_unstemmed Effect of Furans and a Pyran on Several Quorum Sensing Factors in Ralstonia solanacearum
title_sort Effect of Furans and a Pyran on Several Quorum Sensing Factors in Ralstonia solanacearum
dc.creator.none.fl_str_mv Gallego Cruz, Adriana María
Giordano, Walter Fabian
Rosero, Esteban
Echeverri, Fernando
author Gallego Cruz, Adriana María
author_facet Gallego Cruz, Adriana María
Giordano, Walter Fabian
Rosero, Esteban
Echeverri, Fernando
author_role author
author2 Giordano, Walter Fabian
Rosero, Esteban
Echeverri, Fernando
author2_role author
author
author
dc.subject.none.fl_str_mv FURAN
PYRAN
QUORUM SENSING
RALSTONIA
topic FURAN
PYRAN
QUORUM SENSING
RALSTONIA
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Ralstonia solanacearum race 2 is the causative agent of Bacterial Wilt in bananas, a disease also known as Moko disease. Once this bacterium becomes established within a plant, it causes the death of its host. Currently, no treatment is available for Bacterial Wilt, and the disease is able to destroy 100% of the crops in afflicted áreas.This study investigates a non-biocidal control method for R. solanacearum that attempts to nullify the pathogenic effects of R. solanacearum by interfering with the bacteria?s Quorum Sensing (QS) communication system. The effects of several molecules on R. solanacearum growth, biofilm formation and production of acylated homoserine lactone (AHL) autoinducers were analyzed. The results suggested that, of the molecules tested, 5,6 dihydro-2(H)- pyran-2-one most effectively inhibited growth, biofilm formation and AHL production. Furfural, 3-methyl-2(5H)- furanone and methyl 2-furoate also effectively inhibited growth. These molecules affected biofilm formation in a concentration-dependent manner. In addition, 3-methyl-2(5H)-furanone and methyl 2-furoate likewise inhibited AHL production. Therefore, all of these molecules could be useful for controlling R. solanacearum.
Fil: Gallego Cruz, Adriana María. Universidad de Antioquia; Colombia
Fil: Giordano, Walter Fabian. Universidad Nacional de Rio Cuarto. Facultad de Cs.exactas Fisicoquimicas y Naturales. Instituto de Biotecnologia Ambiental y Salud. - Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Cordoba. Instituto de Biotecnologia Ambiental y Salud.; Argentina
Fil: Rosero, Esteban. Universidad de Antioquia; Colombia
Fil: Echeverri, Fernando. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; Argentina
description Ralstonia solanacearum race 2 is the causative agent of Bacterial Wilt in bananas, a disease also known as Moko disease. Once this bacterium becomes established within a plant, it causes the death of its host. Currently, no treatment is available for Bacterial Wilt, and the disease is able to destroy 100% of the crops in afflicted áreas.This study investigates a non-biocidal control method for R. solanacearum that attempts to nullify the pathogenic effects of R. solanacearum by interfering with the bacteria?s Quorum Sensing (QS) communication system. The effects of several molecules on R. solanacearum growth, biofilm formation and production of acylated homoserine lactone (AHL) autoinducers were analyzed. The results suggested that, of the molecules tested, 5,6 dihydro-2(H)- pyran-2-one most effectively inhibited growth, biofilm formation and AHL production. Furfural, 3-methyl-2(5H)- furanone and methyl 2-furoate also effectively inhibited growth. These molecules affected biofilm formation in a concentration-dependent manner. In addition, 3-methyl-2(5H)-furanone and methyl 2-furoate likewise inhibited AHL production. Therefore, all of these molecules could be useful for controlling R. solanacearum.
publishDate 2016
dc.date.none.fl_str_mv 2016-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/107500
Gallego Cruz, Adriana María; Giordano, Walter Fabian; Rosero, Esteban; Echeverri, Fernando; Effect of Furans and a Pyran on Several Quorum Sensing Factors in Ralstonia solanacearum; OMICS International; Journal of oJ Microbial & Biochemical Technology; 08; 06; 11-2016; 478-482
1948-5948
CONICET Digital
CONICET
url http://hdl.handle.net/11336/107500
identifier_str_mv Gallego Cruz, Adriana María; Giordano, Walter Fabian; Rosero, Esteban; Echeverri, Fernando; Effect of Furans and a Pyran on Several Quorum Sensing Factors in Ralstonia solanacearum; OMICS International; Journal of oJ Microbial & Biochemical Technology; 08; 06; 11-2016; 478-482
1948-5948
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.omicsonline.org/open-access/effect-of-furans-and-a-pyran-on-several-quorum-sensing-factors-inralstonia-solanacearum-1948-5948-1000328.php?aid=83726
info:eu-repo/semantics/altIdentifier/doi/10.4172/1948-5948.1000328
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv OMICS International
publisher.none.fl_str_mv OMICS International
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846082924988858368
score 13.22299

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