Binging from food to alcohol: A sequential interaction between binging behaviors in male wistar rats

Autores
Cuesta Martínez, Sergio; Ruiz Leyva, Leandro; Jiménez García, Ana María; Aparicio Mescua, Teresa; López Guarnido, Olga; Pautassi, Ricardo Marcos; Moron, Ignacio; Cendán, Cruz Miguel
Año de publicación
2023
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Developing valid animal models of excessive alcohol (ethanol) and/or highly palatable food self-administration is an essential task to elucidate the neurobiological mechanisms that underlie these behaviors. Previous work has highlighted that ethanol self-administration is modulated by both the induction of aversive states (i.e., stress or frustration) and by the concurrent availability of appetitive stimuli (e.g., food). In our protocol, rats are food deprived for three days until they reach 82%?85% of their ad libitum weight. After that, rats are exposed daily for 10 days to a brief binge or control eating experience with highly sugary and palatable food (i.e., the ingestion of 11.66 and 0.97 kcal/3 min, respectively), which is followed by a two-bottle-choice test (ethanol vs. water) in their home cages for 90 min. This model induces robust binge eating, which is followed by a selective increase in ethanol self-administration. Therefore, this protocol allows to study: a) behavioral and neurobiological factors related to binge eating, b) different stages of alcohol use, and c) interactions between the latter and other addictive-like behaviors, like binge eating.
Fil: Cuesta Martínez, Sergio. Universidad de Granada; España
Fil: Ruiz Leyva, Leandro. Universidad de Granada; España
Fil: Jiménez García, Ana María. Universidad de Granada; España
Fil: Aparicio Mescua, Teresa. Universidad de Granada; España
Fil: López Guarnido, Olga. Universidad de Granada; España
Fil: Pautassi, Ricardo Marcos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Universidad Nacional de Córdoba; Argentina
Fil: Moron, Ignacio. Universidad de Granada; España
Fil: Cendán, Cruz Miguel. Universidad de Granada; España
Materia
Alcohol
Binge drinking
Binge eating
Addiction
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/231333
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Binging from food to alcohol: A sequential interaction between binging behaviors in male wistar ratsCuesta Martínez, SergioRuiz Leyva, LeandroJiménez García, Ana MaríaAparicio Mescua, TeresaLópez Guarnido, OlgaPautassi, Ricardo MarcosMoron, IgnacioCendán, Cruz MiguelAlcoholBinge drinkingBinge eatingAddictionhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Developing valid animal models of excessive alcohol (ethanol) and/or highly palatable food self-administration is an essential task to elucidate the neurobiological mechanisms that underlie these behaviors. Previous work has highlighted that ethanol self-administration is modulated by both the induction of aversive states (i.e., stress or frustration) and by the concurrent availability of appetitive stimuli (e.g., food). In our protocol, rats are food deprived for three days until they reach 82%?85% of their ad libitum weight. After that, rats are exposed daily for 10 days to a brief binge or control eating experience with highly sugary and palatable food (i.e., the ingestion of 11.66 and 0.97 kcal/3 min, respectively), which is followed by a two-bottle-choice test (ethanol vs. water) in their home cages for 90 min. This model induces robust binge eating, which is followed by a selective increase in ethanol self-administration. Therefore, this protocol allows to study: a) behavioral and neurobiological factors related to binge eating, b) different stages of alcohol use, and c) interactions between the latter and other addictive-like behaviors, like binge eating.Fil: Cuesta Martínez, Sergio. Universidad de Granada; EspañaFil: Ruiz Leyva, Leandro. Universidad de Granada; EspañaFil: Jiménez García, Ana María. Universidad de Granada; EspañaFil: Aparicio Mescua, Teresa. Universidad de Granada; EspañaFil: López Guarnido, Olga. Universidad de Granada; EspañaFil: Pautassi, Ricardo Marcos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Moron, Ignacio. Universidad de Granada; EspañaFil: Cendán, Cruz Miguel. Universidad de Granada; EspañaBio-protocol LLC2023-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/231333Cuesta Martínez, Sergio; Ruiz Leyva, Leandro; Jiménez García, Ana María; Aparicio Mescua, Teresa; López Guarnido, Olga; et al.; Binging from food to alcohol: A sequential interaction between binging behaviors in male wistar rats; Bio-protocol LLC; Bio-protocol; 13; 15; 7-2023; 1-122331-8325CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.21769/BioProtoc.4781info:eu-repo/semantics/altIdentifier/url/https://bio-protocol.org/en/bpdetail?id=4781&type=0info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:22:47Zoai:ri.conicet.gov.ar:11336/231333instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:22:47.445CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Binging from food to alcohol: A sequential interaction between binging behaviors in male wistar rats
title Binging from food to alcohol: A sequential interaction between binging behaviors in male wistar rats
spellingShingle Binging from food to alcohol: A sequential interaction between binging behaviors in male wistar rats
Cuesta Martínez, Sergio
Alcohol
Binge drinking
Binge eating
Addiction
title_short Binging from food to alcohol: A sequential interaction between binging behaviors in male wistar rats
title_full Binging from food to alcohol: A sequential interaction between binging behaviors in male wistar rats
title_fullStr Binging from food to alcohol: A sequential interaction between binging behaviors in male wistar rats
title_full_unstemmed Binging from food to alcohol: A sequential interaction between binging behaviors in male wistar rats
title_sort Binging from food to alcohol: A sequential interaction between binging behaviors in male wistar rats
dc.creator.none.fl_str_mv Cuesta Martínez, Sergio
Ruiz Leyva, Leandro
Jiménez García, Ana María
Aparicio Mescua, Teresa
López Guarnido, Olga
Pautassi, Ricardo Marcos
Moron, Ignacio
Cendán, Cruz Miguel
author Cuesta Martínez, Sergio
author_facet Cuesta Martínez, Sergio
Ruiz Leyva, Leandro
Jiménez García, Ana María
Aparicio Mescua, Teresa
López Guarnido, Olga
Pautassi, Ricardo Marcos
Moron, Ignacio
Cendán, Cruz Miguel
author_role author
author2 Ruiz Leyva, Leandro
Jiménez García, Ana María
Aparicio Mescua, Teresa
López Guarnido, Olga
Pautassi, Ricardo Marcos
Moron, Ignacio
Cendán, Cruz Miguel
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Alcohol
Binge drinking
Binge eating
Addiction
topic Alcohol
Binge drinking
Binge eating
Addiction
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Developing valid animal models of excessive alcohol (ethanol) and/or highly palatable food self-administration is an essential task to elucidate the neurobiological mechanisms that underlie these behaviors. Previous work has highlighted that ethanol self-administration is modulated by both the induction of aversive states (i.e., stress or frustration) and by the concurrent availability of appetitive stimuli (e.g., food). In our protocol, rats are food deprived for three days until they reach 82%?85% of their ad libitum weight. After that, rats are exposed daily for 10 days to a brief binge or control eating experience with highly sugary and palatable food (i.e., the ingestion of 11.66 and 0.97 kcal/3 min, respectively), which is followed by a two-bottle-choice test (ethanol vs. water) in their home cages for 90 min. This model induces robust binge eating, which is followed by a selective increase in ethanol self-administration. Therefore, this protocol allows to study: a) behavioral and neurobiological factors related to binge eating, b) different stages of alcohol use, and c) interactions between the latter and other addictive-like behaviors, like binge eating.
Fil: Cuesta Martínez, Sergio. Universidad de Granada; España
Fil: Ruiz Leyva, Leandro. Universidad de Granada; España
Fil: Jiménez García, Ana María. Universidad de Granada; España
Fil: Aparicio Mescua, Teresa. Universidad de Granada; España
Fil: López Guarnido, Olga. Universidad de Granada; España
Fil: Pautassi, Ricardo Marcos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Universidad Nacional de Córdoba; Argentina
Fil: Moron, Ignacio. Universidad de Granada; España
Fil: Cendán, Cruz Miguel. Universidad de Granada; España
description Developing valid animal models of excessive alcohol (ethanol) and/or highly palatable food self-administration is an essential task to elucidate the neurobiological mechanisms that underlie these behaviors. Previous work has highlighted that ethanol self-administration is modulated by both the induction of aversive states (i.e., stress or frustration) and by the concurrent availability of appetitive stimuli (e.g., food). In our protocol, rats are food deprived for three days until they reach 82%?85% of their ad libitum weight. After that, rats are exposed daily for 10 days to a brief binge or control eating experience with highly sugary and palatable food (i.e., the ingestion of 11.66 and 0.97 kcal/3 min, respectively), which is followed by a two-bottle-choice test (ethanol vs. water) in their home cages for 90 min. This model induces robust binge eating, which is followed by a selective increase in ethanol self-administration. Therefore, this protocol allows to study: a) behavioral and neurobiological factors related to binge eating, b) different stages of alcohol use, and c) interactions between the latter and other addictive-like behaviors, like binge eating.
publishDate 2023
dc.date.none.fl_str_mv 2023-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/231333
Cuesta Martínez, Sergio; Ruiz Leyva, Leandro; Jiménez García, Ana María; Aparicio Mescua, Teresa; López Guarnido, Olga; et al.; Binging from food to alcohol: A sequential interaction between binging behaviors in male wistar rats; Bio-protocol LLC; Bio-protocol; 13; 15; 7-2023; 1-12
2331-8325
CONICET Digital
CONICET
url http://hdl.handle.net/11336/231333
identifier_str_mv Cuesta Martínez, Sergio; Ruiz Leyva, Leandro; Jiménez García, Ana María; Aparicio Mescua, Teresa; López Guarnido, Olga; et al.; Binging from food to alcohol: A sequential interaction between binging behaviors in male wistar rats; Bio-protocol LLC; Bio-protocol; 13; 15; 7-2023; 1-12
2331-8325
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.21769/BioProtoc.4781
info:eu-repo/semantics/altIdentifier/url/https://bio-protocol.org/en/bpdetail?id=4781&type=0
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Bio-protocol LLC
publisher.none.fl_str_mv Bio-protocol LLC
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842981255512064000
score 12.48226

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