Monocyte phenotypes: when local education counts
- Autores
- Quintar, Amado Alfredo; Hedrick, Catherine C.; Ley, Klaus
- Año de publicación
- 2015
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Monocytes are a heterogeneous population of phagocytic cells that are generated in the bone marrow and released into the bloodstream. There are two main monocyte subsets in mice: “inflammatory” monocytes that are Ly6Chi CCR2hi CX3 CR1low and “alternative” or “patrolling” monocytes that are Ly6Clow CCR2low CX3 CR1hi. The process of monocyte recruitment and differentiation is still a matter of controversy. In this issue, Dal-Secco et al. report in situ monocyte reprogramming in the liver, from proinflammatory CCR2hi CX3 CR1low cells into reparative CCR2low CX3 CR1hi cells and show, for the first time, that this occurs at the site of injury.
Fil: Quintar, Amado Alfredo. la Jolla Institute For Allergy And Immunology; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Hedrick, Catherine C. . la Jolla Institute For Allergy And Immunology; Estados Unidos
Fil: Ley, Klaus. la Jolla Institute For Allergy And Immunology; Estados Unidos - Materia
-
MONOCYTES
LIVER
INTRAVITAL MCROSCOPY - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/11406
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spelling |
Monocyte phenotypes: when local education countsQuintar, Amado AlfredoHedrick, Catherine C. Ley, KlausMONOCYTESLIVERINTRAVITAL MCROSCOPYhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Monocytes are a heterogeneous population of phagocytic cells that are generated in the bone marrow and released into the bloodstream. There are two main monocyte subsets in mice: “inflammatory” monocytes that are Ly6Chi CCR2hi CX3 CR1low and “alternative” or “patrolling” monocytes that are Ly6Clow CCR2low CX3 CR1hi. The process of monocyte recruitment and differentiation is still a matter of controversy. In this issue, Dal-Secco et al. report in situ monocyte reprogramming in the liver, from proinflammatory CCR2hi CX3 CR1low cells into reparative CCR2low CX3 CR1hi cells and show, for the first time, that this occurs at the site of injury.Fil: Quintar, Amado Alfredo. la Jolla Institute For Allergy And Immunology; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Hedrick, Catherine C. . la Jolla Institute For Allergy And Immunology; Estados UnidosFil: Ley, Klaus. la Jolla Institute For Allergy And Immunology; Estados UnidosRockefeller Univ Press2015-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/11406Quintar, Amado Alfredo; Hedrick, Catherine C. ; Ley, Klaus; Monocyte phenotypes: when local education counts; Rockefeller Univ Press; Journal Of Experimental Medicine; 212; 4; 4-2015; 432-4330022-10071540-9538enginfo:eu-repo/semantics/altIdentifier/doi/10.1084/jem.2124insight1info:eu-repo/semantics/altIdentifier/url/http://jem.rupress.org/content/212/4/432info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:27:23Zoai:ri.conicet.gov.ar:11336/11406instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:27:23.9CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Monocyte phenotypes: when local education counts |
title |
Monocyte phenotypes: when local education counts |
spellingShingle |
Monocyte phenotypes: when local education counts Quintar, Amado Alfredo MONOCYTES LIVER INTRAVITAL MCROSCOPY |
title_short |
Monocyte phenotypes: when local education counts |
title_full |
Monocyte phenotypes: when local education counts |
title_fullStr |
Monocyte phenotypes: when local education counts |
title_full_unstemmed |
Monocyte phenotypes: when local education counts |
title_sort |
Monocyte phenotypes: when local education counts |
dc.creator.none.fl_str_mv |
Quintar, Amado Alfredo Hedrick, Catherine C. Ley, Klaus |
author |
Quintar, Amado Alfredo |
author_facet |
Quintar, Amado Alfredo Hedrick, Catherine C. Ley, Klaus |
author_role |
author |
author2 |
Hedrick, Catherine C. Ley, Klaus |
author2_role |
author author |
dc.subject.none.fl_str_mv |
MONOCYTES LIVER INTRAVITAL MCROSCOPY |
topic |
MONOCYTES LIVER INTRAVITAL MCROSCOPY |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.1 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
Monocytes are a heterogeneous population of phagocytic cells that are generated in the bone marrow and released into the bloodstream. There are two main monocyte subsets in mice: “inflammatory” monocytes that are Ly6Chi CCR2hi CX3 CR1low and “alternative” or “patrolling” monocytes that are Ly6Clow CCR2low CX3 CR1hi. The process of monocyte recruitment and differentiation is still a matter of controversy. In this issue, Dal-Secco et al. report in situ monocyte reprogramming in the liver, from proinflammatory CCR2hi CX3 CR1low cells into reparative CCR2low CX3 CR1hi cells and show, for the first time, that this occurs at the site of injury. Fil: Quintar, Amado Alfredo. la Jolla Institute For Allergy And Immunology; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Hedrick, Catherine C. . la Jolla Institute For Allergy And Immunology; Estados Unidos Fil: Ley, Klaus. la Jolla Institute For Allergy And Immunology; Estados Unidos |
description |
Monocytes are a heterogeneous population of phagocytic cells that are generated in the bone marrow and released into the bloodstream. There are two main monocyte subsets in mice: “inflammatory” monocytes that are Ly6Chi CCR2hi CX3 CR1low and “alternative” or “patrolling” monocytes that are Ly6Clow CCR2low CX3 CR1hi. The process of monocyte recruitment and differentiation is still a matter of controversy. In this issue, Dal-Secco et al. report in situ monocyte reprogramming in the liver, from proinflammatory CCR2hi CX3 CR1low cells into reparative CCR2low CX3 CR1hi cells and show, for the first time, that this occurs at the site of injury. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-04 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/11406 Quintar, Amado Alfredo; Hedrick, Catherine C. ; Ley, Klaus; Monocyte phenotypes: when local education counts; Rockefeller Univ Press; Journal Of Experimental Medicine; 212; 4; 4-2015; 432-433 0022-1007 1540-9538 |
url |
http://hdl.handle.net/11336/11406 |
identifier_str_mv |
Quintar, Amado Alfredo; Hedrick, Catherine C. ; Ley, Klaus; Monocyte phenotypes: when local education counts; Rockefeller Univ Press; Journal Of Experimental Medicine; 212; 4; 4-2015; 432-433 0022-1007 1540-9538 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1084/jem.2124insight1 info:eu-repo/semantics/altIdentifier/url/http://jem.rupress.org/content/212/4/432 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Rockefeller Univ Press |
publisher.none.fl_str_mv |
Rockefeller Univ Press |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844614275678601216 |
score |
13.070432 |