Monocyte phenotypes: when local education counts

Autores
Quintar, Amado Alfredo; Hedrick, Catherine C.; Ley, Klaus
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Monocytes are a heterogeneous population of phagocytic cells that are generated in the bone marrow and released into the bloodstream. There are two main monocyte subsets in mice: “inflammatory” monocytes that are Ly6Chi CCR2hi CX3 CR1low and “alternative” or “patrolling” monocytes that are Ly6Clow CCR2low CX3 CR1hi. The process of monocyte recruitment and differentiation is still a matter of controversy. In this issue, Dal-Secco et al. report in situ monocyte reprogramming in the liver, from proinflammatory CCR2hi CX3 CR1low cells into reparative CCR2low CX3 CR1hi cells and show, for the first time, that this occurs at the site of injury.
Fil: Quintar, Amado Alfredo. la Jolla Institute For Allergy And Immunology; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Hedrick, Catherine C. . la Jolla Institute For Allergy And Immunology; Estados Unidos
Fil: Ley, Klaus. la Jolla Institute For Allergy And Immunology; Estados Unidos
Materia
MONOCYTES
LIVER
INTRAVITAL MCROSCOPY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/11406
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/11406
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Monocyte phenotypes: when local education countsQuintar, Amado AlfredoHedrick, Catherine C. Ley, KlausMONOCYTESLIVERINTRAVITAL MCROSCOPYhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Monocytes are a heterogeneous population of phagocytic cells that are generated in the bone marrow and released into the bloodstream. There are two main monocyte subsets in mice: “inflammatory” monocytes that are Ly6Chi CCR2hi CX3 CR1low and “alternative” or “patrolling” monocytes that are Ly6Clow CCR2low CX3 CR1hi. The process of monocyte recruitment and differentiation is still a matter of controversy. In this issue, Dal-Secco et al. report in situ monocyte reprogramming in the liver, from proinflammatory CCR2hi CX3 CR1low cells into reparative CCR2low CX3 CR1hi cells and show, for the first time, that this occurs at the site of injury.Fil: Quintar, Amado Alfredo. la Jolla Institute For Allergy And Immunology; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Hedrick, Catherine C. . la Jolla Institute For Allergy And Immunology; Estados UnidosFil: Ley, Klaus. la Jolla Institute For Allergy And Immunology; Estados UnidosRockefeller Univ Press2015-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/11406Quintar, Amado Alfredo; Hedrick, Catherine C. ; Ley, Klaus; Monocyte phenotypes: when local education counts; Rockefeller Univ Press; Journal Of Experimental Medicine; 212; 4; 4-2015; 432-4330022-10071540-9538enginfo:eu-repo/semantics/altIdentifier/doi/10.1084/jem.2124insight1info:eu-repo/semantics/altIdentifier/url/http://jem.rupress.org/content/212/4/432info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:24:19Zoai:ri.conicet.gov.ar:11336/11406instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:24:19.422CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Monocyte phenotypes: when local education counts
title Monocyte phenotypes: when local education counts
spellingShingle Monocyte phenotypes: when local education counts
Quintar, Amado Alfredo
MONOCYTES
LIVER
INTRAVITAL MCROSCOPY
title_short Monocyte phenotypes: when local education counts
title_full Monocyte phenotypes: when local education counts
title_fullStr Monocyte phenotypes: when local education counts
title_full_unstemmed Monocyte phenotypes: when local education counts
title_sort Monocyte phenotypes: when local education counts
dc.creator.none.fl_str_mv Quintar, Amado Alfredo
Hedrick, Catherine C.
Ley, Klaus
author Quintar, Amado Alfredo
author_facet Quintar, Amado Alfredo
Hedrick, Catherine C.
Ley, Klaus
author_role author
author2 Hedrick, Catherine C.
Ley, Klaus
author2_role author
author
dc.subject.none.fl_str_mv MONOCYTES
LIVER
INTRAVITAL MCROSCOPY
topic MONOCYTES
LIVER
INTRAVITAL MCROSCOPY
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Monocytes are a heterogeneous population of phagocytic cells that are generated in the bone marrow and released into the bloodstream. There are two main monocyte subsets in mice: “inflammatory” monocytes that are Ly6Chi CCR2hi CX3 CR1low and “alternative” or “patrolling” monocytes that are Ly6Clow CCR2low CX3 CR1hi. The process of monocyte recruitment and differentiation is still a matter of controversy. In this issue, Dal-Secco et al. report in situ monocyte reprogramming in the liver, from proinflammatory CCR2hi CX3 CR1low cells into reparative CCR2low CX3 CR1hi cells and show, for the first time, that this occurs at the site of injury.
Fil: Quintar, Amado Alfredo. la Jolla Institute For Allergy And Immunology; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Hedrick, Catherine C. . la Jolla Institute For Allergy And Immunology; Estados Unidos
Fil: Ley, Klaus. la Jolla Institute For Allergy And Immunology; Estados Unidos
description Monocytes are a heterogeneous population of phagocytic cells that are generated in the bone marrow and released into the bloodstream. There are two main monocyte subsets in mice: “inflammatory” monocytes that are Ly6Chi CCR2hi CX3 CR1low and “alternative” or “patrolling” monocytes that are Ly6Clow CCR2low CX3 CR1hi. The process of monocyte recruitment and differentiation is still a matter of controversy. In this issue, Dal-Secco et al. report in situ monocyte reprogramming in the liver, from proinflammatory CCR2hi CX3 CR1low cells into reparative CCR2low CX3 CR1hi cells and show, for the first time, that this occurs at the site of injury.
publishDate 2015
dc.date.none.fl_str_mv 2015-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/11406
Quintar, Amado Alfredo; Hedrick, Catherine C. ; Ley, Klaus; Monocyte phenotypes: when local education counts; Rockefeller Univ Press; Journal Of Experimental Medicine; 212; 4; 4-2015; 432-433
0022-1007
1540-9538
url http://hdl.handle.net/11336/11406
identifier_str_mv Quintar, Amado Alfredo; Hedrick, Catherine C. ; Ley, Klaus; Monocyte phenotypes: when local education counts; Rockefeller Univ Press; Journal Of Experimental Medicine; 212; 4; 4-2015; 432-433
0022-1007
1540-9538
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1084/jem.2124insight1
info:eu-repo/semantics/altIdentifier/url/http://jem.rupress.org/content/212/4/432
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Rockefeller Univ Press
publisher.none.fl_str_mv Rockefeller Univ Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846083390228398080
score 13.22299

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