High-resolution hyperpolarized J-Spectra with Parahydrogen discrimination

Autores
Prina, Ignacio; Buljubasich Gentiletti, Lisandro; Acosta, Rodolfo Héctor
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Parahydrogen-induced polarization (PHIP) has become a powerful tool not only to overcome the low intrinsic sensitivity of nuclear magnetic resonance (NMR) but also as a probe for catalytic reactions, as a contrast agent in magnetic resonance imaging (MRI), or in analytic chemistry. In complex systems, the antiphase signals coming from parahydrogen in a PASADENA (parahydrogen and synthesis allow dramatically enhanced nuclear alignment) experiment can be partially canceled by the presence of large thermally polarized signals. In the present work, we present a simple method to separate the thermal and hyperpolrized contributions by taking advantage of their very different evolution during a modified CPMG sequence. The separation is obtained in combination with a property of the fast Fourier transform algorithm (FFT). The technique is experimentally demonstrated for a mixture of hyperpolarized 1-hexene and a large amount of CH2Cl2.
Fil: Prina, Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina
Fil: Buljubasich Gentiletti, Lisandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina
Fil: Acosta, Rodolfo Héctor. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina
Materia
Phip
Parahydrogen
Nmr Spectroscopy
Pulse Sequence
Spin Echoes
Cpmg
Pasadena
Hyperpolarization
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/26150
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/26150
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling High-resolution hyperpolarized J-Spectra with Parahydrogen discriminationPrina, IgnacioBuljubasich Gentiletti, LisandroAcosta, Rodolfo HéctorPhipParahydrogenNmr SpectroscopyPulse SequenceSpin EchoesCpmgPasadenaHyperpolarizationhttps://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1Parahydrogen-induced polarization (PHIP) has become a powerful tool not only to overcome the low intrinsic sensitivity of nuclear magnetic resonance (NMR) but also as a probe for catalytic reactions, as a contrast agent in magnetic resonance imaging (MRI), or in analytic chemistry. In complex systems, the antiphase signals coming from parahydrogen in a PASADENA (parahydrogen and synthesis allow dramatically enhanced nuclear alignment) experiment can be partially canceled by the presence of large thermally polarized signals. In the present work, we present a simple method to separate the thermal and hyperpolrized contributions by taking advantage of their very different evolution during a modified CPMG sequence. The separation is obtained in combination with a property of the fast Fourier transform algorithm (FFT). The technique is experimentally demonstrated for a mixture of hyperpolarized 1-hexene and a large amount of CH2Cl2.Fil: Prina, Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; ArgentinaFil: Buljubasich Gentiletti, Lisandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; ArgentinaFil: Acosta, Rodolfo Héctor. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; ArgentinaAmerican Chemical Society2013-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfhttp://hdl.handle.net/11336/26150Prina, Ignacio; Buljubasich Gentiletti, Lisandro; Acosta, Rodolfo Héctor; High-resolution hyperpolarized J-Spectra with Parahydrogen discrimination; American Chemical Society; The Journal of Physical Chemistry Letters; 4; 22; 12-2013; 3924-39281948-7185CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1021/jz402078hinfo:eu-repo/semantics/altIdentifier/url/http://pubs.acs.org/doi/abs/10.1021/jz402078hinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:53:47Zoai:ri.conicet.gov.ar:11336/26150instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:53:47.724CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv High-resolution hyperpolarized J-Spectra with Parahydrogen discrimination
title High-resolution hyperpolarized J-Spectra with Parahydrogen discrimination
spellingShingle High-resolution hyperpolarized J-Spectra with Parahydrogen discrimination
Prina, Ignacio
Phip
Parahydrogen
Nmr Spectroscopy
Pulse Sequence
Spin Echoes
Cpmg
Pasadena
Hyperpolarization
title_short High-resolution hyperpolarized J-Spectra with Parahydrogen discrimination
title_full High-resolution hyperpolarized J-Spectra with Parahydrogen discrimination
title_fullStr High-resolution hyperpolarized J-Spectra with Parahydrogen discrimination
title_full_unstemmed High-resolution hyperpolarized J-Spectra with Parahydrogen discrimination
title_sort High-resolution hyperpolarized J-Spectra with Parahydrogen discrimination
dc.creator.none.fl_str_mv Prina, Ignacio
Buljubasich Gentiletti, Lisandro
Acosta, Rodolfo Héctor
author Prina, Ignacio
author_facet Prina, Ignacio
Buljubasich Gentiletti, Lisandro
Acosta, Rodolfo Héctor
author_role author
author2 Buljubasich Gentiletti, Lisandro
Acosta, Rodolfo Héctor
author2_role author
author
dc.subject.none.fl_str_mv Phip
Parahydrogen
Nmr Spectroscopy
Pulse Sequence
Spin Echoes
Cpmg
Pasadena
Hyperpolarization
topic Phip
Parahydrogen
Nmr Spectroscopy
Pulse Sequence
Spin Echoes
Cpmg
Pasadena
Hyperpolarization
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Parahydrogen-induced polarization (PHIP) has become a powerful tool not only to overcome the low intrinsic sensitivity of nuclear magnetic resonance (NMR) but also as a probe for catalytic reactions, as a contrast agent in magnetic resonance imaging (MRI), or in analytic chemistry. In complex systems, the antiphase signals coming from parahydrogen in a PASADENA (parahydrogen and synthesis allow dramatically enhanced nuclear alignment) experiment can be partially canceled by the presence of large thermally polarized signals. In the present work, we present a simple method to separate the thermal and hyperpolrized contributions by taking advantage of their very different evolution during a modified CPMG sequence. The separation is obtained in combination with a property of the fast Fourier transform algorithm (FFT). The technique is experimentally demonstrated for a mixture of hyperpolarized 1-hexene and a large amount of CH2Cl2.
Fil: Prina, Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina
Fil: Buljubasich Gentiletti, Lisandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina
Fil: Acosta, Rodolfo Héctor. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina
description Parahydrogen-induced polarization (PHIP) has become a powerful tool not only to overcome the low intrinsic sensitivity of nuclear magnetic resonance (NMR) but also as a probe for catalytic reactions, as a contrast agent in magnetic resonance imaging (MRI), or in analytic chemistry. In complex systems, the antiphase signals coming from parahydrogen in a PASADENA (parahydrogen and synthesis allow dramatically enhanced nuclear alignment) experiment can be partially canceled by the presence of large thermally polarized signals. In the present work, we present a simple method to separate the thermal and hyperpolrized contributions by taking advantage of their very different evolution during a modified CPMG sequence. The separation is obtained in combination with a property of the fast Fourier transform algorithm (FFT). The technique is experimentally demonstrated for a mixture of hyperpolarized 1-hexene and a large amount of CH2Cl2.
publishDate 2013
dc.date.none.fl_str_mv 2013-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/26150
Prina, Ignacio; Buljubasich Gentiletti, Lisandro; Acosta, Rodolfo Héctor; High-resolution hyperpolarized J-Spectra with Parahydrogen discrimination; American Chemical Society; The Journal of Physical Chemistry Letters; 4; 22; 12-2013; 3924-3928
1948-7185
CONICET Digital
CONICET
url http://hdl.handle.net/11336/26150
identifier_str_mv Prina, Ignacio; Buljubasich Gentiletti, Lisandro; Acosta, Rodolfo Héctor; High-resolution hyperpolarized J-Spectra with Parahydrogen discrimination; American Chemical Society; The Journal of Physical Chemistry Letters; 4; 22; 12-2013; 3924-3928
1948-7185
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1021/jz402078h
info:eu-repo/semantics/altIdentifier/url/http://pubs.acs.org/doi/abs/10.1021/jz402078h
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/vnd.openxmlformats-officedocument.wordprocessingml.document
application/pdf
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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