Does the Relationship between Prenatal Care and Birth Weight Vary by Oral Clefts? Evidence Using South American and United States Samples

Autores
Nyarko, Kwame A.; Lopez Camelo, Jorge Santiago; Castilla, Eduardo Enrique; Wehby, George
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
OBJECTIVE: To evaluate if the association between prenatal care use and birth weight (BW) varies for infants with cleft lip and/or cleft palate (CL/P), classified into isolated and non-isolated forms, compared with unaffected infants. STUDY DESIGN: The study employed 2 datasets. The first included a multi-country sample of 2405 infants with CL/P and 24046 infants without CL/P born in 1996-2007 in South America. The second was a sample of 2122 infants with CL/P and 297415 without CL/P from the United States 2004 natality dataset. Separate analyses were performed for the South American and United States samples. The association between prenatal care and BW was evaluated separately for isolated CL/P, non-isolated CL/P, and unaffected infants using regression models adjusting for several background characteristics. RESULTS: Prenatal care was associated with improved BW for all infant groups, with greater BW increases for infants with CL/P particularly non-isolated forms. In the South American sample, BW increased by 108, 69, and 40 g on average per prenatal visit for infants with non-isolated CL/P, infants with isolated CL/P, and unaffected infants, respectively. In the United States sample, BW increased by 51, 21, and 16 g on average per prenatal visit for these infant groups, respectively. CONCLUSIONS: Prenatal care was associated with larger BW increases for pregnancies complicated with CL/P, particularly non-isolated forms, compared with unaffected pregnancies. Given that reduced BW is a well-recognized comorbidity of CL/P, the findings highlight the importance of prenatal care for at-risk pregnancies as a tertiary-prevention intervention to reduce the health burden of CL/P.
Fil: Nyarko, Kwame A.. University of Iowa; Estados Unidos
Fil: Lopez Camelo, Jorge Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínica "Norberto Quirno". CEMIC-CONICET.; Argentina. Instituto Oswaldo Cruz; Brasil
Fil: Castilla, Eduardo Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínica "Norberto Quirno". CEMIC-CONICET.; Argentina. Instituto Oswaldo Cruz; Brasil
Fil: Wehby, George. University of Iowa; Estados Unidos
Materia
Birth Weight
Cleft Lip And/Or Cleft Palate
Latin American Collaborative Study of Congenital Malformations
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/22552

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network_name_str CONICET Digital (CONICET)
spelling Does the Relationship between Prenatal Care and Birth Weight Vary by Oral Clefts? Evidence Using South American and United States SamplesNyarko, Kwame A.Lopez Camelo, Jorge SantiagoCastilla, Eduardo EnriqueWehby, GeorgeBirth WeightCleft Lip And/Or Cleft PalateLatin American Collaborative Study of Congenital Malformationshttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3OBJECTIVE: To evaluate if the association between prenatal care use and birth weight (BW) varies for infants with cleft lip and/or cleft palate (CL/P), classified into isolated and non-isolated forms, compared with unaffected infants. STUDY DESIGN: The study employed 2 datasets. The first included a multi-country sample of 2405 infants with CL/P and 24046 infants without CL/P born in 1996-2007 in South America. The second was a sample of 2122 infants with CL/P and 297415 without CL/P from the United States 2004 natality dataset. Separate analyses were performed for the South American and United States samples. The association between prenatal care and BW was evaluated separately for isolated CL/P, non-isolated CL/P, and unaffected infants using regression models adjusting for several background characteristics. RESULTS: Prenatal care was associated with improved BW for all infant groups, with greater BW increases for infants with CL/P particularly non-isolated forms. In the South American sample, BW increased by 108, 69, and 40 g on average per prenatal visit for infants with non-isolated CL/P, infants with isolated CL/P, and unaffected infants, respectively. In the United States sample, BW increased by 51, 21, and 16 g on average per prenatal visit for these infant groups, respectively. CONCLUSIONS: Prenatal care was associated with larger BW increases for pregnancies complicated with CL/P, particularly non-isolated forms, compared with unaffected pregnancies. Given that reduced BW is a well-recognized comorbidity of CL/P, the findings highlight the importance of prenatal care for at-risk pregnancies as a tertiary-prevention intervention to reduce the health burden of CL/P.Fil: Nyarko, Kwame A.. University of Iowa; Estados UnidosFil: Lopez Camelo, Jorge Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínica "Norberto Quirno". CEMIC-CONICET.; Argentina. Instituto Oswaldo Cruz; BrasilFil: Castilla, Eduardo Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínica "Norberto Quirno". CEMIC-CONICET.; Argentina. Instituto Oswaldo Cruz; BrasilFil: Wehby, George. University of Iowa; Estados UnidosElsevier2013-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/mswordapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/22552Nyarko, Kwame A.; Lopez Camelo, Jorge Santiago; Castilla, Eduardo Enrique; Wehby, George; Does the Relationship between Prenatal Care and Birth Weight Vary by Oral Clefts? Evidence Using South American and United States Samples; Elsevier; Journal of Pediatrics; 162; 1; 1-2013; 42-490022-3476CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0022347612007287info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jpeds.2012.06.040info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485451/info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:48:15Zoai:ri.conicet.gov.ar:11336/22552instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:48:16.087CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Does the Relationship between Prenatal Care and Birth Weight Vary by Oral Clefts? Evidence Using South American and United States Samples
title Does the Relationship between Prenatal Care and Birth Weight Vary by Oral Clefts? Evidence Using South American and United States Samples
spellingShingle Does the Relationship between Prenatal Care and Birth Weight Vary by Oral Clefts? Evidence Using South American and United States Samples
Nyarko, Kwame A.
Birth Weight
Cleft Lip And/Or Cleft Palate
Latin American Collaborative Study of Congenital Malformations
title_short Does the Relationship between Prenatal Care and Birth Weight Vary by Oral Clefts? Evidence Using South American and United States Samples
title_full Does the Relationship between Prenatal Care and Birth Weight Vary by Oral Clefts? Evidence Using South American and United States Samples
title_fullStr Does the Relationship between Prenatal Care and Birth Weight Vary by Oral Clefts? Evidence Using South American and United States Samples
title_full_unstemmed Does the Relationship between Prenatal Care and Birth Weight Vary by Oral Clefts? Evidence Using South American and United States Samples
title_sort Does the Relationship between Prenatal Care and Birth Weight Vary by Oral Clefts? Evidence Using South American and United States Samples
dc.creator.none.fl_str_mv Nyarko, Kwame A.
Lopez Camelo, Jorge Santiago
Castilla, Eduardo Enrique
Wehby, George
author Nyarko, Kwame A.
author_facet Nyarko, Kwame A.
Lopez Camelo, Jorge Santiago
Castilla, Eduardo Enrique
Wehby, George
author_role author
author2 Lopez Camelo, Jorge Santiago
Castilla, Eduardo Enrique
Wehby, George
author2_role author
author
author
dc.subject.none.fl_str_mv Birth Weight
Cleft Lip And/Or Cleft Palate
Latin American Collaborative Study of Congenital Malformations
topic Birth Weight
Cleft Lip And/Or Cleft Palate
Latin American Collaborative Study of Congenital Malformations
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv OBJECTIVE: To evaluate if the association between prenatal care use and birth weight (BW) varies for infants with cleft lip and/or cleft palate (CL/P), classified into isolated and non-isolated forms, compared with unaffected infants. STUDY DESIGN: The study employed 2 datasets. The first included a multi-country sample of 2405 infants with CL/P and 24046 infants without CL/P born in 1996-2007 in South America. The second was a sample of 2122 infants with CL/P and 297415 without CL/P from the United States 2004 natality dataset. Separate analyses were performed for the South American and United States samples. The association between prenatal care and BW was evaluated separately for isolated CL/P, non-isolated CL/P, and unaffected infants using regression models adjusting for several background characteristics. RESULTS: Prenatal care was associated with improved BW for all infant groups, with greater BW increases for infants with CL/P particularly non-isolated forms. In the South American sample, BW increased by 108, 69, and 40 g on average per prenatal visit for infants with non-isolated CL/P, infants with isolated CL/P, and unaffected infants, respectively. In the United States sample, BW increased by 51, 21, and 16 g on average per prenatal visit for these infant groups, respectively. CONCLUSIONS: Prenatal care was associated with larger BW increases for pregnancies complicated with CL/P, particularly non-isolated forms, compared with unaffected pregnancies. Given that reduced BW is a well-recognized comorbidity of CL/P, the findings highlight the importance of prenatal care for at-risk pregnancies as a tertiary-prevention intervention to reduce the health burden of CL/P.
Fil: Nyarko, Kwame A.. University of Iowa; Estados Unidos
Fil: Lopez Camelo, Jorge Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínica "Norberto Quirno". CEMIC-CONICET.; Argentina. Instituto Oswaldo Cruz; Brasil
Fil: Castilla, Eduardo Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínica "Norberto Quirno". CEMIC-CONICET.; Argentina. Instituto Oswaldo Cruz; Brasil
Fil: Wehby, George. University of Iowa; Estados Unidos
description OBJECTIVE: To evaluate if the association between prenatal care use and birth weight (BW) varies for infants with cleft lip and/or cleft palate (CL/P), classified into isolated and non-isolated forms, compared with unaffected infants. STUDY DESIGN: The study employed 2 datasets. The first included a multi-country sample of 2405 infants with CL/P and 24046 infants without CL/P born in 1996-2007 in South America. The second was a sample of 2122 infants with CL/P and 297415 without CL/P from the United States 2004 natality dataset. Separate analyses were performed for the South American and United States samples. The association between prenatal care and BW was evaluated separately for isolated CL/P, non-isolated CL/P, and unaffected infants using regression models adjusting for several background characteristics. RESULTS: Prenatal care was associated with improved BW for all infant groups, with greater BW increases for infants with CL/P particularly non-isolated forms. In the South American sample, BW increased by 108, 69, and 40 g on average per prenatal visit for infants with non-isolated CL/P, infants with isolated CL/P, and unaffected infants, respectively. In the United States sample, BW increased by 51, 21, and 16 g on average per prenatal visit for these infant groups, respectively. CONCLUSIONS: Prenatal care was associated with larger BW increases for pregnancies complicated with CL/P, particularly non-isolated forms, compared with unaffected pregnancies. Given that reduced BW is a well-recognized comorbidity of CL/P, the findings highlight the importance of prenatal care for at-risk pregnancies as a tertiary-prevention intervention to reduce the health burden of CL/P.
publishDate 2013
dc.date.none.fl_str_mv 2013-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/22552
Nyarko, Kwame A.; Lopez Camelo, Jorge Santiago; Castilla, Eduardo Enrique; Wehby, George; Does the Relationship between Prenatal Care and Birth Weight Vary by Oral Clefts? Evidence Using South American and United States Samples; Elsevier; Journal of Pediatrics; 162; 1; 1-2013; 42-49
0022-3476
CONICET Digital
CONICET
url http://hdl.handle.net/11336/22552
identifier_str_mv Nyarko, Kwame A.; Lopez Camelo, Jorge Santiago; Castilla, Eduardo Enrique; Wehby, George; Does the Relationship between Prenatal Care and Birth Weight Vary by Oral Clefts? Evidence Using South American and United States Samples; Elsevier; Journal of Pediatrics; 162; 1; 1-2013; 42-49
0022-3476
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0022347612007287
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jpeds.2012.06.040
info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485451/
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
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application/msword
application/vnd.openxmlformats-officedocument.wordprocessingml.document
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
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instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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