Magnetic field inhomogeneities due to co2 incubator shelves: A source of experimental confounding and variability?

Autores
Makinistian, Leonardo; Belyaev, I.
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A thorough assessment of the static magnetic field (SMF) inside a CO2 incubator allowed us to identify non-negligible inhomogeneities close to the floor, ceiling, walls and the door. Given that incubator’s shelves are made of a non-magnetic stainless steel alloy, we did not expect any important effect of them on the SMF. Surprisingly, we did find relatively strong distortion of the SMF due to shelves. Indeed, our high-resolution maps of the SMF revealed that distortion is such that field intensities differing by a factor of up to 36 were measured on the surface of the shelf at locations only few millimetres apart from each other. Furthermore, the most intense of these fields was around five times greater than the ones found inside the incubator (without the metallic shelves in), while the lowest one was around 10 times lower, reaching the so-called hypomagnetic field range. Our findings, together with a survey of the literature on biological effects of hypomagnetic fields, soundly support the idea that SMF inhomogeneities inside incubators, especially due to shelves’ holes, are a potential source of confounding and variability in experiments with cell cultures kept in an incubator.
Fil: Makinistian, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Física Aplicada "Dr. Jorge Andrés Zgrablich". Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Instituto de Física Aplicada "Dr. Jorge Andrés Zgrablich"; Argentina. Slovak Academy of Sciences; Eslovaquia
Fil: Belyaev, I.. Slovak Academy of Sciences; Eslovaquia. Russian Academy of Sciences; Rusia
Materia
BACKGROUND FIELDS OF INCUBATORS
BIOLOGICAL EFFECTS OF WEAK STATIC MAGNETIC FIELDS
STRAIN-INDUCED MAGNETIZATION OF AUSTENITIC STAINLESS STEEL
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/86692
Acceder
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spelling Magnetic field inhomogeneities due to co2 incubator shelves: A source of experimental confounding and variability?Makinistian, LeonardoBelyaev, I.BACKGROUND FIELDS OF INCUBATORSBIOLOGICAL EFFECTS OF WEAK STATIC MAGNETIC FIELDSSTRAIN-INDUCED MAGNETIZATION OF AUSTENITIC STAINLESS STEELhttps://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1A thorough assessment of the static magnetic field (SMF) inside a CO2 incubator allowed us to identify non-negligible inhomogeneities close to the floor, ceiling, walls and the door. Given that incubator’s shelves are made of a non-magnetic stainless steel alloy, we did not expect any important effect of them on the SMF. Surprisingly, we did find relatively strong distortion of the SMF due to shelves. Indeed, our high-resolution maps of the SMF revealed that distortion is such that field intensities differing by a factor of up to 36 were measured on the surface of the shelf at locations only few millimetres apart from each other. Furthermore, the most intense of these fields was around five times greater than the ones found inside the incubator (without the metallic shelves in), while the lowest one was around 10 times lower, reaching the so-called hypomagnetic field range. Our findings, together with a survey of the literature on biological effects of hypomagnetic fields, soundly support the idea that SMF inhomogeneities inside incubators, especially due to shelves’ holes, are a potential source of confounding and variability in experiments with cell cultures kept in an incubator.Fil: Makinistian, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Física Aplicada "Dr. Jorge Andrés Zgrablich". Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Instituto de Física Aplicada "Dr. Jorge Andrés Zgrablich"; Argentina. Slovak Academy of Sciences; EslovaquiaFil: Belyaev, I.. Slovak Academy of Sciences; Eslovaquia. Russian Academy of Sciences; RusiaThe Royal Society2018-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/86692Makinistian, Leonardo; Belyaev, I.; Magnetic field inhomogeneities due to co2 incubator shelves: A source of experimental confounding and variability?; The Royal Society; Royal Society Open Science; 5; 2; 2-2018; 1-102054-5703CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://royalsocietypublishing.org/doi/10.1098/rsos.172095info:eu-repo/semantics/altIdentifier/doi/10.1098/rsos.172095info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T12:14:11Zoai:ri.conicet.gov.ar:11336/86692instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 12:14:11.246CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Magnetic field inhomogeneities due to co2 incubator shelves: A source of experimental confounding and variability?
title Magnetic field inhomogeneities due to co2 incubator shelves: A source of experimental confounding and variability?
spellingShingle Magnetic field inhomogeneities due to co2 incubator shelves: A source of experimental confounding and variability?
Makinistian, Leonardo
BACKGROUND FIELDS OF INCUBATORS
BIOLOGICAL EFFECTS OF WEAK STATIC MAGNETIC FIELDS
STRAIN-INDUCED MAGNETIZATION OF AUSTENITIC STAINLESS STEEL
title_short Magnetic field inhomogeneities due to co2 incubator shelves: A source of experimental confounding and variability?
title_full Magnetic field inhomogeneities due to co2 incubator shelves: A source of experimental confounding and variability?
title_fullStr Magnetic field inhomogeneities due to co2 incubator shelves: A source of experimental confounding and variability?
title_full_unstemmed Magnetic field inhomogeneities due to co2 incubator shelves: A source of experimental confounding and variability?
title_sort Magnetic field inhomogeneities due to co2 incubator shelves: A source of experimental confounding and variability?
dc.creator.none.fl_str_mv Makinistian, Leonardo
Belyaev, I.
author Makinistian, Leonardo
author_facet Makinistian, Leonardo
Belyaev, I.
author_role author
author2 Belyaev, I.
author2_role author
dc.subject.none.fl_str_mv BACKGROUND FIELDS OF INCUBATORS
BIOLOGICAL EFFECTS OF WEAK STATIC MAGNETIC FIELDS
STRAIN-INDUCED MAGNETIZATION OF AUSTENITIC STAINLESS STEEL
topic BACKGROUND FIELDS OF INCUBATORS
BIOLOGICAL EFFECTS OF WEAK STATIC MAGNETIC FIELDS
STRAIN-INDUCED MAGNETIZATION OF AUSTENITIC STAINLESS STEEL
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A thorough assessment of the static magnetic field (SMF) inside a CO2 incubator allowed us to identify non-negligible inhomogeneities close to the floor, ceiling, walls and the door. Given that incubator’s shelves are made of a non-magnetic stainless steel alloy, we did not expect any important effect of them on the SMF. Surprisingly, we did find relatively strong distortion of the SMF due to shelves. Indeed, our high-resolution maps of the SMF revealed that distortion is such that field intensities differing by a factor of up to 36 were measured on the surface of the shelf at locations only few millimetres apart from each other. Furthermore, the most intense of these fields was around five times greater than the ones found inside the incubator (without the metallic shelves in), while the lowest one was around 10 times lower, reaching the so-called hypomagnetic field range. Our findings, together with a survey of the literature on biological effects of hypomagnetic fields, soundly support the idea that SMF inhomogeneities inside incubators, especially due to shelves’ holes, are a potential source of confounding and variability in experiments with cell cultures kept in an incubator.
Fil: Makinistian, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Física Aplicada "Dr. Jorge Andrés Zgrablich". Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Instituto de Física Aplicada "Dr. Jorge Andrés Zgrablich"; Argentina. Slovak Academy of Sciences; Eslovaquia
Fil: Belyaev, I.. Slovak Academy of Sciences; Eslovaquia. Russian Academy of Sciences; Rusia
description A thorough assessment of the static magnetic field (SMF) inside a CO2 incubator allowed us to identify non-negligible inhomogeneities close to the floor, ceiling, walls and the door. Given that incubator’s shelves are made of a non-magnetic stainless steel alloy, we did not expect any important effect of them on the SMF. Surprisingly, we did find relatively strong distortion of the SMF due to shelves. Indeed, our high-resolution maps of the SMF revealed that distortion is such that field intensities differing by a factor of up to 36 were measured on the surface of the shelf at locations only few millimetres apart from each other. Furthermore, the most intense of these fields was around five times greater than the ones found inside the incubator (without the metallic shelves in), while the lowest one was around 10 times lower, reaching the so-called hypomagnetic field range. Our findings, together with a survey of the literature on biological effects of hypomagnetic fields, soundly support the idea that SMF inhomogeneities inside incubators, especially due to shelves’ holes, are a potential source of confounding and variability in experiments with cell cultures kept in an incubator.
publishDate 2018
dc.date.none.fl_str_mv 2018-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/86692
Makinistian, Leonardo; Belyaev, I.; Magnetic field inhomogeneities due to co2 incubator shelves: A source of experimental confounding and variability?; The Royal Society; Royal Society Open Science; 5; 2; 2-2018; 1-10
2054-5703
CONICET Digital
CONICET
url http://hdl.handle.net/11336/86692
identifier_str_mv Makinistian, Leonardo; Belyaev, I.; Magnetic field inhomogeneities due to co2 incubator shelves: A source of experimental confounding and variability?; The Royal Society; Royal Society Open Science; 5; 2; 2-2018; 1-10
2054-5703
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://royalsocietypublishing.org/doi/10.1098/rsos.172095
info:eu-repo/semantics/altIdentifier/doi/10.1098/rsos.172095
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv The Royal Society
publisher.none.fl_str_mv The Royal Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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