On stability of nonzero set-point for non linear impulsive control systems

Autores
D'jorge, Agustina; Anderson, Alejandro Luis; Ferramosca, Antonio; González, Alejandro Hernán; Actis, Marcelo Jesús
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The interest in non-linear impulsive systems (NIS) has been growing due to its impact in application problems such as disease treatments (diabetes, HIV, influenza, among many others), where the control action (drug administration) is given by short-duration pulses followed by time periods of null values. Within this framework the concept of equilibrium needs to be extended (redefined) to allows the system to keep orbiting (between two consecutive pulses) in some state space regions out of the origin, according to usual objectives of most real applications. Although such regions can be characterized by means of a discrete-time system obtained by sampling the NIS at the impulsive times, no agreements have reached about their asymptotic stability (AS). This paper studies the asymptotic stability of control equilibrium orbits for NSI, based on the underlying discrete time system, in order to establish the conditions under which the AS for the latter leads to the AS for the former. Furthermore, based on the latter AS characterization, an impulsive Model Predictive Control (i-MPC) that feasibly stabilizes the non-linear impulsive system is presented. Finally, the proposed stable MPC is applied to two control problems of interest: the intravenous bolus administration of Lithium and the administration of antiretrovirals for HIV treatments.
Fil: D'jorge, Agustina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Anderson, Alejandro Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Ferramosca, Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina. Control System And Automation Laboratory; Italia
Fil: González, Alejandro Hernán. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Actis, Marcelo Jesús. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Matemática Aplicada del Litoral. Universidad Nacional del Litoral. Instituto de Matemática Aplicada del Litoral; Argentina. Universidad Nacional del Litoral. Facultad de Ingeniería Química; Argentina
Materia
IMPULSIVE CONTROL SYSTEMS
STABILITY
MODEL PREDICTIVE CONTROL
NONZERO REGULATION
LITHIUM
HIV
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/174565
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/174565
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling On stability of nonzero set-point for non linear impulsive control systemsD'jorge, AgustinaAnderson, Alejandro LuisFerramosca, AntonioGonzález, Alejandro HernánActis, Marcelo JesúsIMPULSIVE CONTROL SYSTEMSSTABILITYMODEL PREDICTIVE CONTROLNONZERO REGULATIONLITHIUMHIVhttps://purl.org/becyt/ford/1.1https://purl.org/becyt/ford/1The interest in non-linear impulsive systems (NIS) has been growing due to its impact in application problems such as disease treatments (diabetes, HIV, influenza, among many others), where the control action (drug administration) is given by short-duration pulses followed by time periods of null values. Within this framework the concept of equilibrium needs to be extended (redefined) to allows the system to keep orbiting (between two consecutive pulses) in some state space regions out of the origin, according to usual objectives of most real applications. Although such regions can be characterized by means of a discrete-time system obtained by sampling the NIS at the impulsive times, no agreements have reached about their asymptotic stability (AS). This paper studies the asymptotic stability of control equilibrium orbits for NSI, based on the underlying discrete time system, in order to establish the conditions under which the AS for the latter leads to the AS for the former. Furthermore, based on the latter AS characterization, an impulsive Model Predictive Control (i-MPC) that feasibly stabilizes the non-linear impulsive system is presented. Finally, the proposed stable MPC is applied to two control problems of interest: the intravenous bolus administration of Lithium and the administration of antiretrovirals for HIV treatments.Fil: D'jorge, Agustina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaFil: Anderson, Alejandro Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaFil: Ferramosca, Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina. Control System And Automation Laboratory; ItaliaFil: González, Alejandro Hernán. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaFil: Actis, Marcelo Jesús. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Matemática Aplicada del Litoral. Universidad Nacional del Litoral. Instituto de Matemática Aplicada del Litoral; Argentina. Universidad Nacional del Litoral. Facultad de Ingeniería Química; ArgentinaCornell University2020-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/174565D'jorge, Agustina; Anderson, Alejandro Luis; Ferramosca, Antonio; González, Alejandro Hernán; Actis, Marcelo Jesús; On stability of nonzero set-point for non linear impulsive control systems; Cornell University; ArXiv; 11-2020; 1-162331-8422CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/arxiv/https://arxiv.org/abs/2011.12085info:eu-repo/semantics/altIdentifier/doi/10.48550/arXiv.2011.12085info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:01:33Zoai:ri.conicet.gov.ar:11336/174565instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:01:33.345CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv On stability of nonzero set-point for non linear impulsive control systems
title On stability of nonzero set-point for non linear impulsive control systems
spellingShingle On stability of nonzero set-point for non linear impulsive control systems
D'jorge, Agustina
IMPULSIVE CONTROL SYSTEMS
STABILITY
MODEL PREDICTIVE CONTROL
NONZERO REGULATION
LITHIUM
HIV
title_short On stability of nonzero set-point for non linear impulsive control systems
title_full On stability of nonzero set-point for non linear impulsive control systems
title_fullStr On stability of nonzero set-point for non linear impulsive control systems
title_full_unstemmed On stability of nonzero set-point for non linear impulsive control systems
title_sort On stability of nonzero set-point for non linear impulsive control systems
dc.creator.none.fl_str_mv D'jorge, Agustina
Anderson, Alejandro Luis
Ferramosca, Antonio
González, Alejandro Hernán
Actis, Marcelo Jesús
author D'jorge, Agustina
author_facet D'jorge, Agustina
Anderson, Alejandro Luis
Ferramosca, Antonio
González, Alejandro Hernán
Actis, Marcelo Jesús
author_role author
author2 Anderson, Alejandro Luis
Ferramosca, Antonio
González, Alejandro Hernán
Actis, Marcelo Jesús
author2_role author
author
author
author
dc.subject.none.fl_str_mv IMPULSIVE CONTROL SYSTEMS
STABILITY
MODEL PREDICTIVE CONTROL
NONZERO REGULATION
LITHIUM
HIV
topic IMPULSIVE CONTROL SYSTEMS
STABILITY
MODEL PREDICTIVE CONTROL
NONZERO REGULATION
LITHIUM
HIV
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.1
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The interest in non-linear impulsive systems (NIS) has been growing due to its impact in application problems such as disease treatments (diabetes, HIV, influenza, among many others), where the control action (drug administration) is given by short-duration pulses followed by time periods of null values. Within this framework the concept of equilibrium needs to be extended (redefined) to allows the system to keep orbiting (between two consecutive pulses) in some state space regions out of the origin, according to usual objectives of most real applications. Although such regions can be characterized by means of a discrete-time system obtained by sampling the NIS at the impulsive times, no agreements have reached about their asymptotic stability (AS). This paper studies the asymptotic stability of control equilibrium orbits for NSI, based on the underlying discrete time system, in order to establish the conditions under which the AS for the latter leads to the AS for the former. Furthermore, based on the latter AS characterization, an impulsive Model Predictive Control (i-MPC) that feasibly stabilizes the non-linear impulsive system is presented. Finally, the proposed stable MPC is applied to two control problems of interest: the intravenous bolus administration of Lithium and the administration of antiretrovirals for HIV treatments.
Fil: D'jorge, Agustina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Anderson, Alejandro Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Ferramosca, Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina. Control System And Automation Laboratory; Italia
Fil: González, Alejandro Hernán. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Actis, Marcelo Jesús. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Matemática Aplicada del Litoral. Universidad Nacional del Litoral. Instituto de Matemática Aplicada del Litoral; Argentina. Universidad Nacional del Litoral. Facultad de Ingeniería Química; Argentina
description The interest in non-linear impulsive systems (NIS) has been growing due to its impact in application problems such as disease treatments (diabetes, HIV, influenza, among many others), where the control action (drug administration) is given by short-duration pulses followed by time periods of null values. Within this framework the concept of equilibrium needs to be extended (redefined) to allows the system to keep orbiting (between two consecutive pulses) in some state space regions out of the origin, according to usual objectives of most real applications. Although such regions can be characterized by means of a discrete-time system obtained by sampling the NIS at the impulsive times, no agreements have reached about their asymptotic stability (AS). This paper studies the asymptotic stability of control equilibrium orbits for NSI, based on the underlying discrete time system, in order to establish the conditions under which the AS for the latter leads to the AS for the former. Furthermore, based on the latter AS characterization, an impulsive Model Predictive Control (i-MPC) that feasibly stabilizes the non-linear impulsive system is presented. Finally, the proposed stable MPC is applied to two control problems of interest: the intravenous bolus administration of Lithium and the administration of antiretrovirals for HIV treatments.
publishDate 2020
dc.date.none.fl_str_mv 2020-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/174565
D'jorge, Agustina; Anderson, Alejandro Luis; Ferramosca, Antonio; González, Alejandro Hernán; Actis, Marcelo Jesús; On stability of nonzero set-point for non linear impulsive control systems; Cornell University; ArXiv; 11-2020; 1-16
2331-8422
CONICET Digital
CONICET
url http://hdl.handle.net/11336/174565
identifier_str_mv D'jorge, Agustina; Anderson, Alejandro Luis; Ferramosca, Antonio; González, Alejandro Hernán; Actis, Marcelo Jesús; On stability of nonzero set-point for non linear impulsive control systems; Cornell University; ArXiv; 11-2020; 1-16
2331-8422
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/arxiv/https://arxiv.org/abs/2011.12085
info:eu-repo/semantics/altIdentifier/doi/10.48550/arXiv.2011.12085
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Cornell University
publisher.none.fl_str_mv Cornell University
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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