Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing

Autores
Lomlomdjian, A. C.; Terpiluk, V.; Prestupa, Romina Vanesa; Oddo, Silvia Andrea; Giagante, B.; Princich, Juan Pablo; Solis, P.; Kochen, Sara Silvia
Año de publicación
2019
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
Purpose : Most of previous studies in temporal lobe epilepsy have focused on production and comprehension of single word and sentence level analysis, centered in the left hemisphere. Although communication abilities, in which right hemisphere ' s processing is required, have remained unexplored in this population. The purpose of this study was to investigate interictal communication abilities in patients with right lateralized medial temporal lobe epilepsy (RTLE) comparing it with that of patients with left TLE (LTLE) to determine potential impairments and it lateralizing value. Methods : 120 pharmacoresistant TLE patients were evaluated: 55 with RTLE and 65 with LTLE. Subjects underwent a battery of language tests that measure: naming, verbal fluency, verbal inhibition, logic- temporal sequencing, conversational discourse, prosody, comprehension, narrative discourse, indirect speech acts and idiom expressions. Results were compared to those of normal population and deficit was established when performance was below the Z - 1.5 or percentile 5. Statistical significant value was considered at p < 0.001. Results : RTLE compared to LTLE patients, showed significant poorer performance in conversational and narrative discourse, idiom expressions’ and indirect speech ' s comprehension and emotional prosody. RTLE group had a tendency to tangential and disintegrated speech, lack of hierarchical and categorized codification and a significant deficit in social meaning inference. Otherwise, LTLE group showed lower performance in logical temporal sequencing No statistical differences were found in single word level tests analysis. Conclusion : RTLE patients showed communication deficits which are similar to been described in right hemisphere damaged patients due to other etiologies. These communication deficits demonstrated to have a lateraling value and could guide cognitive stimulation programs. Right anterior and mesial temporal structures would have a direct role in prosody processing, and an important role in discourse and pragmatic processing as a link between semantic, language and social processing to build a coherent meaning according to the context.
Fil: Lomlomdjian, A. C.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina
Fil: Terpiluk, V.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina
Fil: Prestupa, Romina Vanesa. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina
Fil: Oddo, Silvia Andrea. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Giagante, B.. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina
Fil: Princich, Juan Pablo. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina
Fil: Solis, P.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina
Fil: Kochen, Sara Silvia. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
33° Congreso Internacional de Epilepsia
Bangkok
Tailandia
International League Against Epilepsy
Materia
EPILEPSY
INMUNO
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/136826

id CONICETDig_26162360659aa84386e5681d5cb57b34
oai_identifier_str oai:ri.conicet.gov.ar:11336/136826
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processingLomlomdjian, A. C.Terpiluk, V.Prestupa, Romina VanesaOddo, Silvia AndreaGiagante, B.Princich, Juan PabloSolis, P.Kochen, Sara SilviaEPILEPSYINMUNOhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Purpose : Most of previous studies in temporal lobe epilepsy have focused on production and comprehension of single word and sentence level analysis, centered in the left hemisphere. Although communication abilities, in which right hemisphere ' s processing is required, have remained unexplored in this population. The purpose of this study was to investigate interictal communication abilities in patients with right lateralized medial temporal lobe epilepsy (RTLE) comparing it with that of patients with left TLE (LTLE) to determine potential impairments and it lateralizing value. Methods : 120 pharmacoresistant TLE patients were evaluated: 55 with RTLE and 65 with LTLE. Subjects underwent a battery of language tests that measure: naming, verbal fluency, verbal inhibition, logic- temporal sequencing, conversational discourse, prosody, comprehension, narrative discourse, indirect speech acts and idiom expressions. Results were compared to those of normal population and deficit was established when performance was below the Z - 1.5 or percentile 5. Statistical significant value was considered at p < 0.001. Results : RTLE compared to LTLE patients, showed significant poorer performance in conversational and narrative discourse, idiom expressions’ and indirect speech ' s comprehension and emotional prosody. RTLE group had a tendency to tangential and disintegrated speech, lack of hierarchical and categorized codification and a significant deficit in social meaning inference. Otherwise, LTLE group showed lower performance in logical temporal sequencing No statistical differences were found in single word level tests analysis. Conclusion : RTLE patients showed communication deficits which are similar to been described in right hemisphere damaged patients due to other etiologies. These communication deficits demonstrated to have a lateraling value and could guide cognitive stimulation programs. Right anterior and mesial temporal structures would have a direct role in prosody processing, and an important role in discourse and pragmatic processing as a link between semantic, language and social processing to build a coherent meaning according to the context.Fil: Lomlomdjian, A. C.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; ArgentinaFil: Terpiluk, V.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; ArgentinaFil: Prestupa, Romina Vanesa. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; ArgentinaFil: Oddo, Silvia Andrea. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Giagante, B.. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; ArgentinaFil: Princich, Juan Pablo. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; ArgentinaFil: Solis, P.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; ArgentinaFil: Kochen, Sara Silvia. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina33° Congreso Internacional de EpilepsiaBangkokTailandiaInternational League Against EpilepsyWiley2019info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectCongresoJournalhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfhttp://hdl.handle.net/11336/136826Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing; 33° Congreso Internacional de Epilepsia; Bangkok; Tailandia; 2019; 36-361528-1167CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1111/epi.16336info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1111/epi.16336Internacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:26:55Zoai:ri.conicet.gov.ar:11336/136826instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:26:55.856CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing
title Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing
spellingShingle Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing
Lomlomdjian, A. C.
EPILEPSY
INMUNO
title_short Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing
title_full Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing
title_fullStr Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing
title_full_unstemmed Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing
title_sort Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing
dc.creator.none.fl_str_mv Lomlomdjian, A. C.
Terpiluk, V.
Prestupa, Romina Vanesa
Oddo, Silvia Andrea
Giagante, B.
Princich, Juan Pablo
Solis, P.
Kochen, Sara Silvia
author Lomlomdjian, A. C.
author_facet Lomlomdjian, A. C.
Terpiluk, V.
Prestupa, Romina Vanesa
Oddo, Silvia Andrea
Giagante, B.
Princich, Juan Pablo
Solis, P.
Kochen, Sara Silvia
author_role author
author2 Terpiluk, V.
Prestupa, Romina Vanesa
Oddo, Silvia Andrea
Giagante, B.
Princich, Juan Pablo
Solis, P.
Kochen, Sara Silvia
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv EPILEPSY
INMUNO
topic EPILEPSY
INMUNO
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Purpose : Most of previous studies in temporal lobe epilepsy have focused on production and comprehension of single word and sentence level analysis, centered in the left hemisphere. Although communication abilities, in which right hemisphere ' s processing is required, have remained unexplored in this population. The purpose of this study was to investigate interictal communication abilities in patients with right lateralized medial temporal lobe epilepsy (RTLE) comparing it with that of patients with left TLE (LTLE) to determine potential impairments and it lateralizing value. Methods : 120 pharmacoresistant TLE patients were evaluated: 55 with RTLE and 65 with LTLE. Subjects underwent a battery of language tests that measure: naming, verbal fluency, verbal inhibition, logic- temporal sequencing, conversational discourse, prosody, comprehension, narrative discourse, indirect speech acts and idiom expressions. Results were compared to those of normal population and deficit was established when performance was below the Z - 1.5 or percentile 5. Statistical significant value was considered at p < 0.001. Results : RTLE compared to LTLE patients, showed significant poorer performance in conversational and narrative discourse, idiom expressions’ and indirect speech ' s comprehension and emotional prosody. RTLE group had a tendency to tangential and disintegrated speech, lack of hierarchical and categorized codification and a significant deficit in social meaning inference. Otherwise, LTLE group showed lower performance in logical temporal sequencing No statistical differences were found in single word level tests analysis. Conclusion : RTLE patients showed communication deficits which are similar to been described in right hemisphere damaged patients due to other etiologies. These communication deficits demonstrated to have a lateraling value and could guide cognitive stimulation programs. Right anterior and mesial temporal structures would have a direct role in prosody processing, and an important role in discourse and pragmatic processing as a link between semantic, language and social processing to build a coherent meaning according to the context.
Fil: Lomlomdjian, A. C.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina
Fil: Terpiluk, V.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina
Fil: Prestupa, Romina Vanesa. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina
Fil: Oddo, Silvia Andrea. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Giagante, B.. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina
Fil: Princich, Juan Pablo. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina
Fil: Solis, P.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina
Fil: Kochen, Sara Silvia. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
33° Congreso Internacional de Epilepsia
Bangkok
Tailandia
International League Against Epilepsy
description Purpose : Most of previous studies in temporal lobe epilepsy have focused on production and comprehension of single word and sentence level analysis, centered in the left hemisphere. Although communication abilities, in which right hemisphere ' s processing is required, have remained unexplored in this population. The purpose of this study was to investigate interictal communication abilities in patients with right lateralized medial temporal lobe epilepsy (RTLE) comparing it with that of patients with left TLE (LTLE) to determine potential impairments and it lateralizing value. Methods : 120 pharmacoresistant TLE patients were evaluated: 55 with RTLE and 65 with LTLE. Subjects underwent a battery of language tests that measure: naming, verbal fluency, verbal inhibition, logic- temporal sequencing, conversational discourse, prosody, comprehension, narrative discourse, indirect speech acts and idiom expressions. Results were compared to those of normal population and deficit was established when performance was below the Z - 1.5 or percentile 5. Statistical significant value was considered at p < 0.001. Results : RTLE compared to LTLE patients, showed significant poorer performance in conversational and narrative discourse, idiom expressions’ and indirect speech ' s comprehension and emotional prosody. RTLE group had a tendency to tangential and disintegrated speech, lack of hierarchical and categorized codification and a significant deficit in social meaning inference. Otherwise, LTLE group showed lower performance in logical temporal sequencing No statistical differences were found in single word level tests analysis. Conclusion : RTLE patients showed communication deficits which are similar to been described in right hemisphere damaged patients due to other etiologies. These communication deficits demonstrated to have a lateraling value and could guide cognitive stimulation programs. Right anterior and mesial temporal structures would have a direct role in prosody processing, and an important role in discourse and pragmatic processing as a link between semantic, language and social processing to build a coherent meaning according to the context.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
Congreso
Journal
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
status_str publishedVersion
format conferenceObject
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/136826
Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing; 33° Congreso Internacional de Epilepsia; Bangkok; Tailandia; 2019; 36-36
1528-1167
CONICET Digital
CONICET
url http://hdl.handle.net/11336/136826
identifier_str_mv Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing; 33° Congreso Internacional de Epilepsia; Bangkok; Tailandia; 2019; 36-36
1528-1167
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1111/epi.16336
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1111/epi.16336
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/vnd.openxmlformats-officedocument.wordprocessingml.document
application/pdf
dc.coverage.none.fl_str_mv Internacional
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846083411554336768
score 12.891075