Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing
- Autores
- Lomlomdjian, A. C.; Terpiluk, V.; Prestupa, Romina Vanesa; Oddo, Silvia Andrea; Giagante, B.; Princich, Juan Pablo; Solis, P.; Kochen, Sara Silvia
- Año de publicación
- 2019
- Idioma
- inglés
- Tipo de recurso
- documento de conferencia
- Estado
- versión publicada
- Descripción
- Purpose : Most of previous studies in temporal lobe epilepsy have focused on production and comprehension of single word and sentence level analysis, centered in the left hemisphere. Although communication abilities, in which right hemisphere ' s processing is required, have remained unexplored in this population. The purpose of this study was to investigate interictal communication abilities in patients with right lateralized medial temporal lobe epilepsy (RTLE) comparing it with that of patients with left TLE (LTLE) to determine potential impairments and it lateralizing value. Methods : 120 pharmacoresistant TLE patients were evaluated: 55 with RTLE and 65 with LTLE. Subjects underwent a battery of language tests that measure: naming, verbal fluency, verbal inhibition, logic- temporal sequencing, conversational discourse, prosody, comprehension, narrative discourse, indirect speech acts and idiom expressions. Results were compared to those of normal population and deficit was established when performance was below the Z - 1.5 or percentile 5. Statistical significant value was considered at p < 0.001. Results : RTLE compared to LTLE patients, showed significant poorer performance in conversational and narrative discourse, idiom expressions’ and indirect speech ' s comprehension and emotional prosody. RTLE group had a tendency to tangential and disintegrated speech, lack of hierarchical and categorized codification and a significant deficit in social meaning inference. Otherwise, LTLE group showed lower performance in logical temporal sequencing No statistical differences were found in single word level tests analysis. Conclusion : RTLE patients showed communication deficits which are similar to been described in right hemisphere damaged patients due to other etiologies. These communication deficits demonstrated to have a lateraling value and could guide cognitive stimulation programs. Right anterior and mesial temporal structures would have a direct role in prosody processing, and an important role in discourse and pragmatic processing as a link between semantic, language and social processing to build a coherent meaning according to the context.
Fil: Lomlomdjian, A. C.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina
Fil: Terpiluk, V.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina
Fil: Prestupa, Romina Vanesa. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina
Fil: Oddo, Silvia Andrea. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Giagante, B.. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina
Fil: Princich, Juan Pablo. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina
Fil: Solis, P.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina
Fil: Kochen, Sara Silvia. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
33° Congreso Internacional de Epilepsia
Bangkok
Tailandia
International League Against Epilepsy - Materia
-
EPILEPSY
INMUNO - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/136826
Ver los metadatos del registro completo
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Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processingLomlomdjian, A. C.Terpiluk, V.Prestupa, Romina VanesaOddo, Silvia AndreaGiagante, B.Princich, Juan PabloSolis, P.Kochen, Sara SilviaEPILEPSYINMUNOhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Purpose : Most of previous studies in temporal lobe epilepsy have focused on production and comprehension of single word and sentence level analysis, centered in the left hemisphere. Although communication abilities, in which right hemisphere ' s processing is required, have remained unexplored in this population. The purpose of this study was to investigate interictal communication abilities in patients with right lateralized medial temporal lobe epilepsy (RTLE) comparing it with that of patients with left TLE (LTLE) to determine potential impairments and it lateralizing value. Methods : 120 pharmacoresistant TLE patients were evaluated: 55 with RTLE and 65 with LTLE. Subjects underwent a battery of language tests that measure: naming, verbal fluency, verbal inhibition, logic- temporal sequencing, conversational discourse, prosody, comprehension, narrative discourse, indirect speech acts and idiom expressions. Results were compared to those of normal population and deficit was established when performance was below the Z - 1.5 or percentile 5. Statistical significant value was considered at p < 0.001. Results : RTLE compared to LTLE patients, showed significant poorer performance in conversational and narrative discourse, idiom expressions’ and indirect speech ' s comprehension and emotional prosody. RTLE group had a tendency to tangential and disintegrated speech, lack of hierarchical and categorized codification and a significant deficit in social meaning inference. Otherwise, LTLE group showed lower performance in logical temporal sequencing No statistical differences were found in single word level tests analysis. Conclusion : RTLE patients showed communication deficits which are similar to been described in right hemisphere damaged patients due to other etiologies. These communication deficits demonstrated to have a lateraling value and could guide cognitive stimulation programs. Right anterior and mesial temporal structures would have a direct role in prosody processing, and an important role in discourse and pragmatic processing as a link between semantic, language and social processing to build a coherent meaning according to the context.Fil: Lomlomdjian, A. C.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; ArgentinaFil: Terpiluk, V.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; ArgentinaFil: Prestupa, Romina Vanesa. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; ArgentinaFil: Oddo, Silvia Andrea. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Giagante, B.. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; ArgentinaFil: Princich, Juan Pablo. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; ArgentinaFil: Solis, P.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; ArgentinaFil: Kochen, Sara Silvia. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina33° Congreso Internacional de EpilepsiaBangkokTailandiaInternational League Against EpilepsyWiley2019info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectCongresoJournalhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfhttp://hdl.handle.net/11336/136826Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing; 33° Congreso Internacional de Epilepsia; Bangkok; Tailandia; 2019; 36-361528-1167CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1111/epi.16336info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1111/epi.16336Internacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:26:55Zoai:ri.conicet.gov.ar:11336/136826instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:26:55.856CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing |
title |
Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing |
spellingShingle |
Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing Lomlomdjian, A. C. EPILEPSY INMUNO |
title_short |
Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing |
title_full |
Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing |
title_fullStr |
Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing |
title_full_unstemmed |
Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing |
title_sort |
Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing |
dc.creator.none.fl_str_mv |
Lomlomdjian, A. C. Terpiluk, V. Prestupa, Romina Vanesa Oddo, Silvia Andrea Giagante, B. Princich, Juan Pablo Solis, P. Kochen, Sara Silvia |
author |
Lomlomdjian, A. C. |
author_facet |
Lomlomdjian, A. C. Terpiluk, V. Prestupa, Romina Vanesa Oddo, Silvia Andrea Giagante, B. Princich, Juan Pablo Solis, P. Kochen, Sara Silvia |
author_role |
author |
author2 |
Terpiluk, V. Prestupa, Romina Vanesa Oddo, Silvia Andrea Giagante, B. Princich, Juan Pablo Solis, P. Kochen, Sara Silvia |
author2_role |
author author author author author author author |
dc.subject.none.fl_str_mv |
EPILEPSY INMUNO |
topic |
EPILEPSY INMUNO |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.2 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
Purpose : Most of previous studies in temporal lobe epilepsy have focused on production and comprehension of single word and sentence level analysis, centered in the left hemisphere. Although communication abilities, in which right hemisphere ' s processing is required, have remained unexplored in this population. The purpose of this study was to investigate interictal communication abilities in patients with right lateralized medial temporal lobe epilepsy (RTLE) comparing it with that of patients with left TLE (LTLE) to determine potential impairments and it lateralizing value. Methods : 120 pharmacoresistant TLE patients were evaluated: 55 with RTLE and 65 with LTLE. Subjects underwent a battery of language tests that measure: naming, verbal fluency, verbal inhibition, logic- temporal sequencing, conversational discourse, prosody, comprehension, narrative discourse, indirect speech acts and idiom expressions. Results were compared to those of normal population and deficit was established when performance was below the Z - 1.5 or percentile 5. Statistical significant value was considered at p < 0.001. Results : RTLE compared to LTLE patients, showed significant poorer performance in conversational and narrative discourse, idiom expressions’ and indirect speech ' s comprehension and emotional prosody. RTLE group had a tendency to tangential and disintegrated speech, lack of hierarchical and categorized codification and a significant deficit in social meaning inference. Otherwise, LTLE group showed lower performance in logical temporal sequencing No statistical differences were found in single word level tests analysis. Conclusion : RTLE patients showed communication deficits which are similar to been described in right hemisphere damaged patients due to other etiologies. These communication deficits demonstrated to have a lateraling value and could guide cognitive stimulation programs. Right anterior and mesial temporal structures would have a direct role in prosody processing, and an important role in discourse and pragmatic processing as a link between semantic, language and social processing to build a coherent meaning according to the context. Fil: Lomlomdjian, A. C.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina Fil: Terpiluk, V.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina Fil: Prestupa, Romina Vanesa. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina Fil: Oddo, Silvia Andrea. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Giagante, B.. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina Fil: Princich, Juan Pablo. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina Fil: Solis, P.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina Fil: Kochen, Sara Silvia. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina. Gobierno de la Provincia de Buenos Aires. Hospital El Cruce Doctor Nestor Carlos Kirchner. Centro de Medicina Traslacional.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina 33° Congreso Internacional de Epilepsia Bangkok Tailandia International League Against Epilepsy |
description |
Purpose : Most of previous studies in temporal lobe epilepsy have focused on production and comprehension of single word and sentence level analysis, centered in the left hemisphere. Although communication abilities, in which right hemisphere ' s processing is required, have remained unexplored in this population. The purpose of this study was to investigate interictal communication abilities in patients with right lateralized medial temporal lobe epilepsy (RTLE) comparing it with that of patients with left TLE (LTLE) to determine potential impairments and it lateralizing value. Methods : 120 pharmacoresistant TLE patients were evaluated: 55 with RTLE and 65 with LTLE. Subjects underwent a battery of language tests that measure: naming, verbal fluency, verbal inhibition, logic- temporal sequencing, conversational discourse, prosody, comprehension, narrative discourse, indirect speech acts and idiom expressions. Results were compared to those of normal population and deficit was established when performance was below the Z - 1.5 or percentile 5. Statistical significant value was considered at p < 0.001. Results : RTLE compared to LTLE patients, showed significant poorer performance in conversational and narrative discourse, idiom expressions’ and indirect speech ' s comprehension and emotional prosody. RTLE group had a tendency to tangential and disintegrated speech, lack of hierarchical and categorized codification and a significant deficit in social meaning inference. Otherwise, LTLE group showed lower performance in logical temporal sequencing No statistical differences were found in single word level tests analysis. Conclusion : RTLE patients showed communication deficits which are similar to been described in right hemisphere damaged patients due to other etiologies. These communication deficits demonstrated to have a lateraling value and could guide cognitive stimulation programs. Right anterior and mesial temporal structures would have a direct role in prosody processing, and an important role in discourse and pragmatic processing as a link between semantic, language and social processing to build a coherent meaning according to the context. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019 |
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info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/conferenceObject Congreso Journal http://purl.org/coar/resource_type/c_5794 info:ar-repo/semantics/documentoDeConferencia |
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publishedVersion |
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conferenceObject |
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http://hdl.handle.net/11336/136826 Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing; 33° Congreso Internacional de Epilepsia; Bangkok; Tailandia; 2019; 36-36 1528-1167 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/136826 |
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Language and communication abilities in temporal lobe epilepsy patients: right vs. left hemisphere's processing; 33° Congreso Internacional de Epilepsia; Bangkok; Tailandia; 2019; 36-36 1528-1167 CONICET Digital CONICET |
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eng |
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eng |
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Wiley |
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dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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