Effects of pretraining treatment with testosterone on successive and anticipatory negative contrast

Autores
Justel, Nadia; Ruetti, Eliana Martha; Mustaca, Alba Elisabeth; Papini, Mauricio Roberto
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Previous research indicated that the suppression of consummatory behavior that follows incentive downshift in male rats is attenuated by testosterone (T) administration during training. The present experiments were designed to assess the role of pretraining T administration on two incentive contrast situations in consummatory behavior: successive negative contrast (cSNC) and anticipatory negative contrast (cANC). In cSNC (Experiment 1), a downshift from 32% to 4% sucrose leads to behavioral suppression relative to an unshifted, 4% sucrose condition (the cSNC effect). Pretraining T administration enhanced consummatory behavior directed at 4% sucrose, without affecting behavior directed at 32% sucrose. This effect obscured a reduction in the cSNC effect by the T treatment that was only detected when a proportional measure of behavior was used. In cANC (Experiment 2), groups received access to two bottles per day separated by a short midtrial interval. Consumption of 4% sucrose is suppressed when the second bottle offers 32% sucrose, relative to 4% sucrose (the cANC effect). Pretraining T did not affect the cANC effect, known to be insensitive to treatment with anxiolytics. These results suggest an anxiolytic-like effect of testosterone in adjustment to incentive downshifts.
Fil: Justel, Nadia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Ruetti, Eliana Martha. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Mustaca, Alba Elisabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Papini, Mauricio Roberto. Texas Christian University; Estados Unidos
Materia
Consummatory Anticipatory Contrast
Consummatory Successive Negative Contrast
Rats
Testosterone
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/67338
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Effects of pretraining treatment with testosterone on successive and anticipatory negative contrastJustel, NadiaRuetti, Eliana MarthaMustaca, Alba ElisabethPapini, Mauricio RobertoConsummatory Anticipatory ContrastConsummatory Successive Negative ContrastRatsTestosteronehttps://purl.org/becyt/ford/5.1https://purl.org/becyt/ford/5Previous research indicated that the suppression of consummatory behavior that follows incentive downshift in male rats is attenuated by testosterone (T) administration during training. The present experiments were designed to assess the role of pretraining T administration on two incentive contrast situations in consummatory behavior: successive negative contrast (cSNC) and anticipatory negative contrast (cANC). In cSNC (Experiment 1), a downshift from 32% to 4% sucrose leads to behavioral suppression relative to an unshifted, 4% sucrose condition (the cSNC effect). Pretraining T administration enhanced consummatory behavior directed at 4% sucrose, without affecting behavior directed at 32% sucrose. This effect obscured a reduction in the cSNC effect by the T treatment that was only detected when a proportional measure of behavior was used. In cANC (Experiment 2), groups received access to two bottles per day separated by a short midtrial interval. Consumption of 4% sucrose is suppressed when the second bottle offers 32% sucrose, relative to 4% sucrose (the cANC effect). Pretraining T did not affect the cANC effect, known to be insensitive to treatment with anxiolytics. These results suggest an anxiolytic-like effect of testosterone in adjustment to incentive downshifts.Fil: Justel, Nadia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaFil: Ruetti, Eliana Martha. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaFil: Mustaca, Alba Elisabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaFil: Papini, Mauricio Roberto. Texas Christian University; Estados UnidosPergamon-Elsevier Science Ltd2012-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/67338Justel, Nadia; Ruetti, Eliana Martha; Mustaca, Alba Elisabeth; Papini, Mauricio Roberto; Effects of pretraining treatment with testosterone on successive and anticipatory negative contrast; Pergamon-Elsevier Science Ltd; Physiology And Behavior; 105; 4; 2-2012; 933-9370031-9384CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.physbeh.2011.11.012info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0031938411005324info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:35:29Zoai:ri.conicet.gov.ar:11336/67338instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:35:29.927CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Effects of pretraining treatment with testosterone on successive and anticipatory negative contrast
title Effects of pretraining treatment with testosterone on successive and anticipatory negative contrast
spellingShingle Effects of pretraining treatment with testosterone on successive and anticipatory negative contrast
Justel, Nadia
Consummatory Anticipatory Contrast
Consummatory Successive Negative Contrast
Rats
Testosterone
title_short Effects of pretraining treatment with testosterone on successive and anticipatory negative contrast
title_full Effects of pretraining treatment with testosterone on successive and anticipatory negative contrast
title_fullStr Effects of pretraining treatment with testosterone on successive and anticipatory negative contrast
title_full_unstemmed Effects of pretraining treatment with testosterone on successive and anticipatory negative contrast
title_sort Effects of pretraining treatment with testosterone on successive and anticipatory negative contrast
dc.creator.none.fl_str_mv Justel, Nadia
Ruetti, Eliana Martha
Mustaca, Alba Elisabeth
Papini, Mauricio Roberto
author Justel, Nadia
author_facet Justel, Nadia
Ruetti, Eliana Martha
Mustaca, Alba Elisabeth
Papini, Mauricio Roberto
author_role author
author2 Ruetti, Eliana Martha
Mustaca, Alba Elisabeth
Papini, Mauricio Roberto
author2_role author
author
author
dc.subject.none.fl_str_mv Consummatory Anticipatory Contrast
Consummatory Successive Negative Contrast
Rats
Testosterone
topic Consummatory Anticipatory Contrast
Consummatory Successive Negative Contrast
Rats
Testosterone
purl_subject.fl_str_mv https://purl.org/becyt/ford/5.1
https://purl.org/becyt/ford/5
dc.description.none.fl_txt_mv Previous research indicated that the suppression of consummatory behavior that follows incentive downshift in male rats is attenuated by testosterone (T) administration during training. The present experiments were designed to assess the role of pretraining T administration on two incentive contrast situations in consummatory behavior: successive negative contrast (cSNC) and anticipatory negative contrast (cANC). In cSNC (Experiment 1), a downshift from 32% to 4% sucrose leads to behavioral suppression relative to an unshifted, 4% sucrose condition (the cSNC effect). Pretraining T administration enhanced consummatory behavior directed at 4% sucrose, without affecting behavior directed at 32% sucrose. This effect obscured a reduction in the cSNC effect by the T treatment that was only detected when a proportional measure of behavior was used. In cANC (Experiment 2), groups received access to two bottles per day separated by a short midtrial interval. Consumption of 4% sucrose is suppressed when the second bottle offers 32% sucrose, relative to 4% sucrose (the cANC effect). Pretraining T did not affect the cANC effect, known to be insensitive to treatment with anxiolytics. These results suggest an anxiolytic-like effect of testosterone in adjustment to incentive downshifts.
Fil: Justel, Nadia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Ruetti, Eliana Martha. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Mustaca, Alba Elisabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Papini, Mauricio Roberto. Texas Christian University; Estados Unidos
description Previous research indicated that the suppression of consummatory behavior that follows incentive downshift in male rats is attenuated by testosterone (T) administration during training. The present experiments were designed to assess the role of pretraining T administration on two incentive contrast situations in consummatory behavior: successive negative contrast (cSNC) and anticipatory negative contrast (cANC). In cSNC (Experiment 1), a downshift from 32% to 4% sucrose leads to behavioral suppression relative to an unshifted, 4% sucrose condition (the cSNC effect). Pretraining T administration enhanced consummatory behavior directed at 4% sucrose, without affecting behavior directed at 32% sucrose. This effect obscured a reduction in the cSNC effect by the T treatment that was only detected when a proportional measure of behavior was used. In cANC (Experiment 2), groups received access to two bottles per day separated by a short midtrial interval. Consumption of 4% sucrose is suppressed when the second bottle offers 32% sucrose, relative to 4% sucrose (the cANC effect). Pretraining T did not affect the cANC effect, known to be insensitive to treatment with anxiolytics. These results suggest an anxiolytic-like effect of testosterone in adjustment to incentive downshifts.
publishDate 2012
dc.date.none.fl_str_mv 2012-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/67338
Justel, Nadia; Ruetti, Eliana Martha; Mustaca, Alba Elisabeth; Papini, Mauricio Roberto; Effects of pretraining treatment with testosterone on successive and anticipatory negative contrast; Pergamon-Elsevier Science Ltd; Physiology And Behavior; 105; 4; 2-2012; 933-937
0031-9384
CONICET Digital
CONICET
url http://hdl.handle.net/11336/67338
identifier_str_mv Justel, Nadia; Ruetti, Eliana Martha; Mustaca, Alba Elisabeth; Papini, Mauricio Roberto; Effects of pretraining treatment with testosterone on successive and anticipatory negative contrast; Pergamon-Elsevier Science Ltd; Physiology And Behavior; 105; 4; 2-2012; 933-937
0031-9384
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.physbeh.2011.11.012
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0031938411005324
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.069144

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