Effects of testosterone administration and gonadectomy on incentive downshift and open field activity in rats

Autores
Justel, Nadia; Ruetti, Eliana Martha; Bentosela, Mariana; Mustaca, Alba Elisabeth; Papini, Mauricio Roberto
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Previous research showed that the effects of incentive downshift in male rats are attenuated by a pretrial opportunity to ejaculate. Because ejaculation raises testosterone (T) levels and has anxiolytic-like effects in male rats, the present experiments were designed to assess the role of T and gonadectomy (GDX) on two situations involving incentive downshift. In consummatory successive negative contrast, a downshift from 32% to 4% sucrose leads to consummatory suppression. T alleviates such suppression (Experiment 1), but GDX does not affect it (Experiment 3). In consummatory extinction, animals are downshifted from 32% sucrose to an empty sipper tube. T enhances consummatory extinction (Experiment 2), but GDX does not affect it (Experiment 4). In agreement with published results, T increases (Experiment 2) and GDX reduces (Experiment 4) activity in the central area of an open field, thus behaviorally validating these manipulations. The results are discussed in terms of the anxiolytic-like properties of androgen hormones. © 2012 Elsevier Inc.
Fil: Justel, Nadia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Ruetti, Eliana Martha. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Bentosela, Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Mustaca, Alba Elisabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Papini, Mauricio Roberto. Texas Christian University; Estados Unidos
Materia
Anxiety
Consummatory Extinction
Frustration
Gonadectomy
Incentive Contrast
Open Field Activity
Rats
Testosterone
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/67403
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Effects of testosterone administration and gonadectomy on incentive downshift and open field activity in ratsJustel, NadiaRuetti, Eliana MarthaBentosela, MarianaMustaca, Alba ElisabethPapini, Mauricio RobertoAnxietyConsummatory ExtinctionFrustrationGonadectomyIncentive ContrastOpen Field ActivityRatsTestosteronehttps://purl.org/becyt/ford/5.1https://purl.org/becyt/ford/5Previous research showed that the effects of incentive downshift in male rats are attenuated by a pretrial opportunity to ejaculate. Because ejaculation raises testosterone (T) levels and has anxiolytic-like effects in male rats, the present experiments were designed to assess the role of T and gonadectomy (GDX) on two situations involving incentive downshift. In consummatory successive negative contrast, a downshift from 32% to 4% sucrose leads to consummatory suppression. T alleviates such suppression (Experiment 1), but GDX does not affect it (Experiment 3). In consummatory extinction, animals are downshifted from 32% sucrose to an empty sipper tube. T enhances consummatory extinction (Experiment 2), but GDX does not affect it (Experiment 4). In agreement with published results, T increases (Experiment 2) and GDX reduces (Experiment 4) activity in the central area of an open field, thus behaviorally validating these manipulations. The results are discussed in terms of the anxiolytic-like properties of androgen hormones. © 2012 Elsevier Inc.Fil: Justel, Nadia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaFil: Ruetti, Eliana Martha. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaFil: Bentosela, Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaFil: Mustaca, Alba Elisabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaFil: Papini, Mauricio Roberto. Texas Christian University; Estados UnidosPergamon-Elsevier Science Ltd2012-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/67403Justel, Nadia; Ruetti, Eliana Martha; Bentosela, Mariana; Mustaca, Alba Elisabeth; Papini, Mauricio Roberto; Effects of testosterone administration and gonadectomy on incentive downshift and open field activity in rats; Pergamon-Elsevier Science Ltd; Physiology And Behavior; 106; 5; 7-2012; 657-6630031-9384CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.physbeh.2012.05.003info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S0031938412001904info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:19:44Zoai:ri.conicet.gov.ar:11336/67403instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:19:45.063CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Effects of testosterone administration and gonadectomy on incentive downshift and open field activity in rats
title Effects of testosterone administration and gonadectomy on incentive downshift and open field activity in rats
spellingShingle Effects of testosterone administration and gonadectomy on incentive downshift and open field activity in rats
Justel, Nadia
Anxiety
Consummatory Extinction
Frustration
Gonadectomy
Incentive Contrast
Open Field Activity
Rats
Testosterone
title_short Effects of testosterone administration and gonadectomy on incentive downshift and open field activity in rats
title_full Effects of testosterone administration and gonadectomy on incentive downshift and open field activity in rats
title_fullStr Effects of testosterone administration and gonadectomy on incentive downshift and open field activity in rats
title_full_unstemmed Effects of testosterone administration and gonadectomy on incentive downshift and open field activity in rats
title_sort Effects of testosterone administration and gonadectomy on incentive downshift and open field activity in rats
dc.creator.none.fl_str_mv Justel, Nadia
Ruetti, Eliana Martha
Bentosela, Mariana
Mustaca, Alba Elisabeth
Papini, Mauricio Roberto
author Justel, Nadia
author_facet Justel, Nadia
Ruetti, Eliana Martha
Bentosela, Mariana
Mustaca, Alba Elisabeth
Papini, Mauricio Roberto
author_role author
author2 Ruetti, Eliana Martha
Bentosela, Mariana
Mustaca, Alba Elisabeth
Papini, Mauricio Roberto
author2_role author
author
author
author
dc.subject.none.fl_str_mv Anxiety
Consummatory Extinction
Frustration
Gonadectomy
Incentive Contrast
Open Field Activity
Rats
Testosterone
topic Anxiety
Consummatory Extinction
Frustration
Gonadectomy
Incentive Contrast
Open Field Activity
Rats
Testosterone
purl_subject.fl_str_mv https://purl.org/becyt/ford/5.1
https://purl.org/becyt/ford/5
dc.description.none.fl_txt_mv Previous research showed that the effects of incentive downshift in male rats are attenuated by a pretrial opportunity to ejaculate. Because ejaculation raises testosterone (T) levels and has anxiolytic-like effects in male rats, the present experiments were designed to assess the role of T and gonadectomy (GDX) on two situations involving incentive downshift. In consummatory successive negative contrast, a downshift from 32% to 4% sucrose leads to consummatory suppression. T alleviates such suppression (Experiment 1), but GDX does not affect it (Experiment 3). In consummatory extinction, animals are downshifted from 32% sucrose to an empty sipper tube. T enhances consummatory extinction (Experiment 2), but GDX does not affect it (Experiment 4). In agreement with published results, T increases (Experiment 2) and GDX reduces (Experiment 4) activity in the central area of an open field, thus behaviorally validating these manipulations. The results are discussed in terms of the anxiolytic-like properties of androgen hormones. © 2012 Elsevier Inc.
Fil: Justel, Nadia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Ruetti, Eliana Martha. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Bentosela, Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Mustaca, Alba Elisabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Papini, Mauricio Roberto. Texas Christian University; Estados Unidos
description Previous research showed that the effects of incentive downshift in male rats are attenuated by a pretrial opportunity to ejaculate. Because ejaculation raises testosterone (T) levels and has anxiolytic-like effects in male rats, the present experiments were designed to assess the role of T and gonadectomy (GDX) on two situations involving incentive downshift. In consummatory successive negative contrast, a downshift from 32% to 4% sucrose leads to consummatory suppression. T alleviates such suppression (Experiment 1), but GDX does not affect it (Experiment 3). In consummatory extinction, animals are downshifted from 32% sucrose to an empty sipper tube. T enhances consummatory extinction (Experiment 2), but GDX does not affect it (Experiment 4). In agreement with published results, T increases (Experiment 2) and GDX reduces (Experiment 4) activity in the central area of an open field, thus behaviorally validating these manipulations. The results are discussed in terms of the anxiolytic-like properties of androgen hormones. © 2012 Elsevier Inc.
publishDate 2012
dc.date.none.fl_str_mv 2012-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/67403
Justel, Nadia; Ruetti, Eliana Martha; Bentosela, Mariana; Mustaca, Alba Elisabeth; Papini, Mauricio Roberto; Effects of testosterone administration and gonadectomy on incentive downshift and open field activity in rats; Pergamon-Elsevier Science Ltd; Physiology And Behavior; 106; 5; 7-2012; 657-663
0031-9384
CONICET Digital
CONICET
url http://hdl.handle.net/11336/67403
identifier_str_mv Justel, Nadia; Ruetti, Eliana Martha; Bentosela, Mariana; Mustaca, Alba Elisabeth; Papini, Mauricio Roberto; Effects of testosterone administration and gonadectomy on incentive downshift and open field activity in rats; Pergamon-Elsevier Science Ltd; Physiology And Behavior; 106; 5; 7-2012; 657-663
0031-9384
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.physbeh.2012.05.003
info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S0031938412001904
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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