One step derivatization and preconcentration microextraction technique for determination of bisphenol A in beverage samples by gas chromatography-mass spectrometry

Autores
Fontana, Ariel Ramón; Muñoz de Toro, Monica Milagros; Altamirano, Jorgelina Cecilia
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A simple technique based on ultrasound-assisted emulsification microextraction in-situ derivatization (USAEME-ISD) is proposed for the one step derivatization, extraction and preconcentration of bisphenol A (BPA) in beverages samples prior to gas chromatography-mass spectrometry (GC-MS) analysis. BPA was in-situ derivatized with acetic anhydride and simultaneously extracted and preconcentrated by using USAEME. Variables affecting the extraction efficiency of BPA were evaluated. Under optimal experimental conditions, the detection limit (LOD) was 38 ng L-1 with a relative standard deviation (RSD) value of 11.6 %. The linear working range was 100-1250 ng g-1 the coefficient of estimation (r2) of the calibration curve was higher than 0.9971. The robustness of the proposed methodology was probed by developing a recovery study at two concentrations (125 and 500 ng L-1) over different beverages samples. This study led to a satisfactory result achieving recoveries higher than 82 % showed a successfully robustness for determination of BPA in samples of food safety interest.
Fil: Fontana, Ariel Ramón. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Regional de Investigaciones Científicas y Tecnológicas. Laboratorio de Investigaciones y Servicios Ambientales Mendoza; Argentina
Fil: Muñoz de Toro, Monica Milagros. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Departamento de Fisiología. Laboratorio de Endocrinología y Tumores Hormonodependientes; Argentina
Fil: Altamirano, Jorgelina Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Regional de Investigaciones Científicas y Tecnológicas. Laboratorio de Investigaciones y Servicios Ambientales Mendoza; Argentina
Materia
Bisphenol A
Ultrasound Assisted Emulsification Microextraction
In-Situ Derivatization
Food Analysis
Beverage Samples
Gas Chromatography-Mass Spectrometry
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/41919
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/41919
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling One step derivatization and preconcentration microextraction technique for determination of bisphenol A in beverage samples by gas chromatography-mass spectrometryFontana, Ariel RamónMuñoz de Toro, Monica MilagrosAltamirano, Jorgelina CeciliaBisphenol AUltrasound Assisted Emulsification MicroextractionIn-Situ DerivatizationFood AnalysisBeverage SamplesGas Chromatography-Mass Spectrometryhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1A simple technique based on ultrasound-assisted emulsification microextraction in-situ derivatization (USAEME-ISD) is proposed for the one step derivatization, extraction and preconcentration of bisphenol A (BPA) in beverages samples prior to gas chromatography-mass spectrometry (GC-MS) analysis. BPA was in-situ derivatized with acetic anhydride and simultaneously extracted and preconcentrated by using USAEME. Variables affecting the extraction efficiency of BPA were evaluated. Under optimal experimental conditions, the detection limit (LOD) was 38 ng L-1 with a relative standard deviation (RSD) value of 11.6 %. The linear working range was 100-1250 ng g-1 the coefficient of estimation (r2) of the calibration curve was higher than 0.9971. The robustness of the proposed methodology was probed by developing a recovery study at two concentrations (125 and 500 ng L-1) over different beverages samples. This study led to a satisfactory result achieving recoveries higher than 82 % showed a successfully robustness for determination of BPA in samples of food safety interest.Fil: Fontana, Ariel Ramón. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Regional de Investigaciones Científicas y Tecnológicas. Laboratorio de Investigaciones y Servicios Ambientales Mendoza; ArgentinaFil: Muñoz de Toro, Monica Milagros. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Departamento de Fisiología. Laboratorio de Endocrinología y Tumores Hormonodependientes; ArgentinaFil: Altamirano, Jorgelina Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Regional de Investigaciones Científicas y Tecnológicas. Laboratorio de Investigaciones y Servicios Ambientales Mendoza; ArgentinaAmerican Chemical Society2011-03-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/41919Fontana, Ariel Ramón; Muñoz de Toro, Monica Milagros; Altamirano, Jorgelina Cecilia; One step derivatization and preconcentration microextraction technique for determination of bisphenol A in beverage samples by gas chromatography-mass spectrometry; American Chemical Society; Journal of Agricultural and Food Chemistry; 59; 8; 7-3-2011; 3559-35650021-8561CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://pubs.acs.org/doi/pdf/10.1021/jf104622xinfo:eu-repo/semantics/altIdentifier/doi/10.1021/jf104622xinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:02:41Zoai:ri.conicet.gov.ar:11336/41919instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:02:41.355CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv One step derivatization and preconcentration microextraction technique for determination of bisphenol A in beverage samples by gas chromatography-mass spectrometry
title One step derivatization and preconcentration microextraction technique for determination of bisphenol A in beverage samples by gas chromatography-mass spectrometry
spellingShingle One step derivatization and preconcentration microextraction technique for determination of bisphenol A in beverage samples by gas chromatography-mass spectrometry
Fontana, Ariel Ramón
Bisphenol A
Ultrasound Assisted Emulsification Microextraction
In-Situ Derivatization
Food Analysis
Beverage Samples
Gas Chromatography-Mass Spectrometry
title_short One step derivatization and preconcentration microextraction technique for determination of bisphenol A in beverage samples by gas chromatography-mass spectrometry
title_full One step derivatization and preconcentration microextraction technique for determination of bisphenol A in beverage samples by gas chromatography-mass spectrometry
title_fullStr One step derivatization and preconcentration microextraction technique for determination of bisphenol A in beverage samples by gas chromatography-mass spectrometry
title_full_unstemmed One step derivatization and preconcentration microextraction technique for determination of bisphenol A in beverage samples by gas chromatography-mass spectrometry
title_sort One step derivatization and preconcentration microextraction technique for determination of bisphenol A in beverage samples by gas chromatography-mass spectrometry
dc.creator.none.fl_str_mv Fontana, Ariel Ramón
Muñoz de Toro, Monica Milagros
Altamirano, Jorgelina Cecilia
author Fontana, Ariel Ramón
author_facet Fontana, Ariel Ramón
Muñoz de Toro, Monica Milagros
Altamirano, Jorgelina Cecilia
author_role author
author2 Muñoz de Toro, Monica Milagros
Altamirano, Jorgelina Cecilia
author2_role author
author
dc.subject.none.fl_str_mv Bisphenol A
Ultrasound Assisted Emulsification Microextraction
In-Situ Derivatization
Food Analysis
Beverage Samples
Gas Chromatography-Mass Spectrometry
topic Bisphenol A
Ultrasound Assisted Emulsification Microextraction
In-Situ Derivatization
Food Analysis
Beverage Samples
Gas Chromatography-Mass Spectrometry
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A simple technique based on ultrasound-assisted emulsification microextraction in-situ derivatization (USAEME-ISD) is proposed for the one step derivatization, extraction and preconcentration of bisphenol A (BPA) in beverages samples prior to gas chromatography-mass spectrometry (GC-MS) analysis. BPA was in-situ derivatized with acetic anhydride and simultaneously extracted and preconcentrated by using USAEME. Variables affecting the extraction efficiency of BPA were evaluated. Under optimal experimental conditions, the detection limit (LOD) was 38 ng L-1 with a relative standard deviation (RSD) value of 11.6 %. The linear working range was 100-1250 ng g-1 the coefficient of estimation (r2) of the calibration curve was higher than 0.9971. The robustness of the proposed methodology was probed by developing a recovery study at two concentrations (125 and 500 ng L-1) over different beverages samples. This study led to a satisfactory result achieving recoveries higher than 82 % showed a successfully robustness for determination of BPA in samples of food safety interest.
Fil: Fontana, Ariel Ramón. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Regional de Investigaciones Científicas y Tecnológicas. Laboratorio de Investigaciones y Servicios Ambientales Mendoza; Argentina
Fil: Muñoz de Toro, Monica Milagros. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Departamento de Fisiología. Laboratorio de Endocrinología y Tumores Hormonodependientes; Argentina
Fil: Altamirano, Jorgelina Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Regional de Investigaciones Científicas y Tecnológicas. Laboratorio de Investigaciones y Servicios Ambientales Mendoza; Argentina
description A simple technique based on ultrasound-assisted emulsification microextraction in-situ derivatization (USAEME-ISD) is proposed for the one step derivatization, extraction and preconcentration of bisphenol A (BPA) in beverages samples prior to gas chromatography-mass spectrometry (GC-MS) analysis. BPA was in-situ derivatized with acetic anhydride and simultaneously extracted and preconcentrated by using USAEME. Variables affecting the extraction efficiency of BPA were evaluated. Under optimal experimental conditions, the detection limit (LOD) was 38 ng L-1 with a relative standard deviation (RSD) value of 11.6 %. The linear working range was 100-1250 ng g-1 the coefficient of estimation (r2) of the calibration curve was higher than 0.9971. The robustness of the proposed methodology was probed by developing a recovery study at two concentrations (125 and 500 ng L-1) over different beverages samples. This study led to a satisfactory result achieving recoveries higher than 82 % showed a successfully robustness for determination of BPA in samples of food safety interest.
publishDate 2011
dc.date.none.fl_str_mv 2011-03-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/41919
Fontana, Ariel Ramón; Muñoz de Toro, Monica Milagros; Altamirano, Jorgelina Cecilia; One step derivatization and preconcentration microextraction technique for determination of bisphenol A in beverage samples by gas chromatography-mass spectrometry; American Chemical Society; Journal of Agricultural and Food Chemistry; 59; 8; 7-3-2011; 3559-3565
0021-8561
CONICET Digital
CONICET
url http://hdl.handle.net/11336/41919
identifier_str_mv Fontana, Ariel Ramón; Muñoz de Toro, Monica Milagros; Altamirano, Jorgelina Cecilia; One step derivatization and preconcentration microextraction technique for determination of bisphenol A in beverage samples by gas chromatography-mass spectrometry; American Chemical Society; Journal of Agricultural and Food Chemistry; 59; 8; 7-3-2011; 3559-3565
0021-8561
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://pubs.acs.org/doi/pdf/10.1021/jf104622x
info:eu-repo/semantics/altIdentifier/doi/10.1021/jf104622x
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269769160458240
score 13.13397

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