Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions

Autores
Rodriguez Granillo, Gaston Alfredo; Rosales, Miguel A.; Renes, Paola; Diez, Eduardo; Pereyra, Jorge; Gomez, Estela; De Lillo, Gustavo; Degrossi, Elina; Rodriguez, Alfredo E.; McFadden, Eugene P.
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Hypoenhanced regions on multidetector CT (MDCT) coronary angiography correlate with myocardial hyperperfusion. In addition to a limited capillary density, chronic myocardial infarction (MI) commonly contains a considerable amount of adipose tissue. Objective: We explored whether regional myocardial hypoenhancement on contrast-enhanced MDCT could be identified with standard coronary artery calcium (CAC) scoring acquisitions with noncontrast CT. Methods: Consecutive patients with a history of MI who were referred for contrast-enhanced MDCT from November 2006 until March 2009 were studied. Noncontrast CT for CAC scoring was also performed. The correlation between regional myocardial hypoenhancement on contrast-enhanced CT and regional myocardial hypoattenuated areas on noncontrast CT was defined. Results: Eighty-three patients (mean age, 61.5 ± 12.5 years; n = 67; 81% male) with previous MI were studied. A total of 1411 myocardial segments were evaluated. Two hundred thirty-nine segments (17%) showed myocardial hypoenhancement by MDCT and 140 segments (9.6%) by CAC. On a patient level, noncontrast CT showed a sensitivity, specificity, positive predictive value, (PPV) and negative predictive value (NPV) of 66% (95% CI, 0.53-0.77), 100% (95% CI, 0.76-1.00), 100% (95% CI, 0.90-1.00), and 41% (95% CI, 0.26-0.58), respectively, to detect myocardial hypoenhancement. On a per segment level, noncontrast CT showed a sensitivity, specificity, PPV, and NPV of 58% (95% CI, 0.51-0.64), 100% (95% CI, 0.99-1.00), 99% (95% CI, 0.94-1.00), and 92% (95% CI, 0.90-0.93), respectively, to detect myocardial hypoenhancement. Conclusions: Our findings suggest that chronic MI can be detected with standard CAC scoring acquisitions. © 2010 Society of Cardiovascular Computed Tomography.
Fil: Rodriguez Granillo, Gaston Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: Rosales, Miguel A.. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: Renes, Paola. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: Diez, Eduardo. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: Pereyra, Jorge. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: Gomez, Estela. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: De Lillo, Gustavo. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: Degrossi, Elina. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: Rodriguez, Alfredo E.. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: McFadden, Eugene P.. Cork University Hospital; Irlanda
Materia
COMPUTED TOMOGRAPHY
INFARCT EXTENSION
NECROSIS
PERFUSION DEFECT
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/186531
Acceder
id CONICETDig_23df6b7bb0a0fb7b81ec297ac209d658
oai_identifier_str oai:ri.conicet.gov.ar:11336/186531
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitionsRodriguez Granillo, Gaston AlfredoRosales, Miguel A.Renes, PaolaDiez, EduardoPereyra, JorgeGomez, EstelaDe Lillo, GustavoDegrossi, ElinaRodriguez, Alfredo E.McFadden, Eugene P.COMPUTED TOMOGRAPHYINFARCT EXTENSIONNECROSISPERFUSION DEFECThttps://purl.org/becyt/ford/3.5https://purl.org/becyt/ford/3Background: Hypoenhanced regions on multidetector CT (MDCT) coronary angiography correlate with myocardial hyperperfusion. In addition to a limited capillary density, chronic myocardial infarction (MI) commonly contains a considerable amount of adipose tissue. Objective: We explored whether regional myocardial hypoenhancement on contrast-enhanced MDCT could be identified with standard coronary artery calcium (CAC) scoring acquisitions with noncontrast CT. Methods: Consecutive patients with a history of MI who were referred for contrast-enhanced MDCT from November 2006 until March 2009 were studied. Noncontrast CT for CAC scoring was also performed. The correlation between regional myocardial hypoenhancement on contrast-enhanced CT and regional myocardial hypoattenuated areas on noncontrast CT was defined. Results: Eighty-three patients (mean age, 61.5 ± 12.5 years; n = 67; 81% male) with previous MI were studied. A total of 1411 myocardial segments were evaluated. Two hundred thirty-nine segments (17%) showed myocardial hypoenhancement by MDCT and 140 segments (9.6%) by CAC. On a patient level, noncontrast CT showed a sensitivity, specificity, positive predictive value, (PPV) and negative predictive value (NPV) of 66% (95% CI, 0.53-0.77), 100% (95% CI, 0.76-1.00), 100% (95% CI, 0.90-1.00), and 41% (95% CI, 0.26-0.58), respectively, to detect myocardial hypoenhancement. On a per segment level, noncontrast CT showed a sensitivity, specificity, PPV, and NPV of 58% (95% CI, 0.51-0.64), 100% (95% CI, 0.99-1.00), 99% (95% CI, 0.94-1.00), and 92% (95% CI, 0.90-0.93), respectively, to detect myocardial hypoenhancement. Conclusions: Our findings suggest that chronic MI can be detected with standard CAC scoring acquisitions. © 2010 Society of Cardiovascular Computed Tomography.Fil: Rodriguez Granillo, Gaston Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Sanatorio "Otamendi y Miroli S. A."; ArgentinaFil: Rosales, Miguel A.. Sanatorio "Otamendi y Miroli S. A."; ArgentinaFil: Renes, Paola. Sanatorio "Otamendi y Miroli S. A."; ArgentinaFil: Diez, Eduardo. Sanatorio "Otamendi y Miroli S. A."; ArgentinaFil: Pereyra, Jorge. Sanatorio "Otamendi y Miroli S. A."; ArgentinaFil: Gomez, Estela. Sanatorio "Otamendi y Miroli S. A."; ArgentinaFil: De Lillo, Gustavo. Sanatorio "Otamendi y Miroli S. A."; ArgentinaFil: Degrossi, Elina. Sanatorio "Otamendi y Miroli S. A."; ArgentinaFil: Rodriguez, Alfredo E.. Sanatorio "Otamendi y Miroli S. A."; ArgentinaFil: McFadden, Eugene P.. Cork University Hospital; IrlandaElsevier2010-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/186531Rodriguez Granillo, Gaston Alfredo; Rosales, Miguel A.; Renes, Paola; Diez, Eduardo; Pereyra, Jorge; et al.; Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions; Elsevier; Journal of Cardiovascular Computed Tomography; 4; 2; 3-2010; 99-1071934-5925CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.jcct.2009.12.003info:eu-repo/semantics/altIdentifier/url/https://www.journalofcardiovascularct.com/article/S1934-5925(09)00639-X/fulltextinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:10:38Zoai:ri.conicet.gov.ar:11336/186531instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:10:38.434CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions
title Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions
spellingShingle Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions
Rodriguez Granillo, Gaston Alfredo
COMPUTED TOMOGRAPHY
INFARCT EXTENSION
NECROSIS
PERFUSION DEFECT
title_short Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions
title_full Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions
title_fullStr Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions
title_full_unstemmed Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions
title_sort Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions
dc.creator.none.fl_str_mv Rodriguez Granillo, Gaston Alfredo
Rosales, Miguel A.
Renes, Paola
Diez, Eduardo
Pereyra, Jorge
Gomez, Estela
De Lillo, Gustavo
Degrossi, Elina
Rodriguez, Alfredo E.
McFadden, Eugene P.
author Rodriguez Granillo, Gaston Alfredo
author_facet Rodriguez Granillo, Gaston Alfredo
Rosales, Miguel A.
Renes, Paola
Diez, Eduardo
Pereyra, Jorge
Gomez, Estela
De Lillo, Gustavo
Degrossi, Elina
Rodriguez, Alfredo E.
McFadden, Eugene P.
author_role author
author2 Rosales, Miguel A.
Renes, Paola
Diez, Eduardo
Pereyra, Jorge
Gomez, Estela
De Lillo, Gustavo
Degrossi, Elina
Rodriguez, Alfredo E.
McFadden, Eugene P.
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv COMPUTED TOMOGRAPHY
INFARCT EXTENSION
NECROSIS
PERFUSION DEFECT
topic COMPUTED TOMOGRAPHY
INFARCT EXTENSION
NECROSIS
PERFUSION DEFECT
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.5
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Background: Hypoenhanced regions on multidetector CT (MDCT) coronary angiography correlate with myocardial hyperperfusion. In addition to a limited capillary density, chronic myocardial infarction (MI) commonly contains a considerable amount of adipose tissue. Objective: We explored whether regional myocardial hypoenhancement on contrast-enhanced MDCT could be identified with standard coronary artery calcium (CAC) scoring acquisitions with noncontrast CT. Methods: Consecutive patients with a history of MI who were referred for contrast-enhanced MDCT from November 2006 until March 2009 were studied. Noncontrast CT for CAC scoring was also performed. The correlation between regional myocardial hypoenhancement on contrast-enhanced CT and regional myocardial hypoattenuated areas on noncontrast CT was defined. Results: Eighty-three patients (mean age, 61.5 ± 12.5 years; n = 67; 81% male) with previous MI were studied. A total of 1411 myocardial segments were evaluated. Two hundred thirty-nine segments (17%) showed myocardial hypoenhancement by MDCT and 140 segments (9.6%) by CAC. On a patient level, noncontrast CT showed a sensitivity, specificity, positive predictive value, (PPV) and negative predictive value (NPV) of 66% (95% CI, 0.53-0.77), 100% (95% CI, 0.76-1.00), 100% (95% CI, 0.90-1.00), and 41% (95% CI, 0.26-0.58), respectively, to detect myocardial hypoenhancement. On a per segment level, noncontrast CT showed a sensitivity, specificity, PPV, and NPV of 58% (95% CI, 0.51-0.64), 100% (95% CI, 0.99-1.00), 99% (95% CI, 0.94-1.00), and 92% (95% CI, 0.90-0.93), respectively, to detect myocardial hypoenhancement. Conclusions: Our findings suggest that chronic MI can be detected with standard CAC scoring acquisitions. © 2010 Society of Cardiovascular Computed Tomography.
Fil: Rodriguez Granillo, Gaston Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: Rosales, Miguel A.. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: Renes, Paola. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: Diez, Eduardo. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: Pereyra, Jorge. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: Gomez, Estela. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: De Lillo, Gustavo. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: Degrossi, Elina. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: Rodriguez, Alfredo E.. Sanatorio "Otamendi y Miroli S. A."; Argentina
Fil: McFadden, Eugene P.. Cork University Hospital; Irlanda
description Background: Hypoenhanced regions on multidetector CT (MDCT) coronary angiography correlate with myocardial hyperperfusion. In addition to a limited capillary density, chronic myocardial infarction (MI) commonly contains a considerable amount of adipose tissue. Objective: We explored whether regional myocardial hypoenhancement on contrast-enhanced MDCT could be identified with standard coronary artery calcium (CAC) scoring acquisitions with noncontrast CT. Methods: Consecutive patients with a history of MI who were referred for contrast-enhanced MDCT from November 2006 until March 2009 were studied. Noncontrast CT for CAC scoring was also performed. The correlation between regional myocardial hypoenhancement on contrast-enhanced CT and regional myocardial hypoattenuated areas on noncontrast CT was defined. Results: Eighty-three patients (mean age, 61.5 ± 12.5 years; n = 67; 81% male) with previous MI were studied. A total of 1411 myocardial segments were evaluated. Two hundred thirty-nine segments (17%) showed myocardial hypoenhancement by MDCT and 140 segments (9.6%) by CAC. On a patient level, noncontrast CT showed a sensitivity, specificity, positive predictive value, (PPV) and negative predictive value (NPV) of 66% (95% CI, 0.53-0.77), 100% (95% CI, 0.76-1.00), 100% (95% CI, 0.90-1.00), and 41% (95% CI, 0.26-0.58), respectively, to detect myocardial hypoenhancement. On a per segment level, noncontrast CT showed a sensitivity, specificity, PPV, and NPV of 58% (95% CI, 0.51-0.64), 100% (95% CI, 0.99-1.00), 99% (95% CI, 0.94-1.00), and 92% (95% CI, 0.90-0.93), respectively, to detect myocardial hypoenhancement. Conclusions: Our findings suggest that chronic MI can be detected with standard CAC scoring acquisitions. © 2010 Society of Cardiovascular Computed Tomography.
publishDate 2010
dc.date.none.fl_str_mv 2010-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/186531
Rodriguez Granillo, Gaston Alfredo; Rosales, Miguel A.; Renes, Paola; Diez, Eduardo; Pereyra, Jorge; et al.; Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions; Elsevier; Journal of Cardiovascular Computed Tomography; 4; 2; 3-2010; 99-107
1934-5925
CONICET Digital
CONICET
url http://hdl.handle.net/11336/186531
identifier_str_mv Rodriguez Granillo, Gaston Alfredo; Rosales, Miguel A.; Renes, Paola; Diez, Eduardo; Pereyra, Jorge; et al.; Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions; Elsevier; Journal of Cardiovascular Computed Tomography; 4; 2; 3-2010; 99-107
1934-5925
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jcct.2009.12.003
info:eu-repo/semantics/altIdentifier/url/https://www.journalofcardiovascularct.com/article/S1934-5925(09)00639-X/fulltext
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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