Noise-induced hippocampal damage: potential mechanisms

Autores
Molina, Sonia Jazmín; Guelman, Laura Ruth
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Exposure to noise of high intensities (>80 dB) is considered a stressful event and might produce both auditory and extra-auditory damage, including different central nervous system (CNS) injuries. Within the CNS, the hippocampus (HC), a structure related to several cognitive functions, has shown to be particularly susceptible to the effects of noise. Human and animal studies have demonstrated that exposure to noise can generate different HC-related alterations, including morphological, functional and behavioral changes (Molina et al. 2016b, 2019; Nadhimi and Llano 2020). Unfortunately, little is known about the mechanisms involved in noise-induced hippocampal damage and more research is needed to understand how the different alterations are caused. In addition, considering that noise exposure constitutes a public health problem that is increasing in urbanized societies, accurate knowledge of these mechanisms has clinical relevance as it can lead to develop preventive strategies. In this perspective, the possible mechanisms involved in noise-induced hippocampal cell damage will be discussed, as well as the pathways through which these mechanisms could be triggered by noise exposure.
Fil: Molina, Sonia Jazmín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; Argentina
Fil: Guelman, Laura Ruth. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; Argentina
Materia
Noise
Hippocampus
stress
damage
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/178737
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Noise-induced hippocampal damage: potential mechanismsMolina, Sonia JazmínGuelman, Laura RuthNoiseHippocampusstressdamagehttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Exposure to noise of high intensities (>80 dB) is considered a stressful event and might produce both auditory and extra-auditory damage, including different central nervous system (CNS) injuries. Within the CNS, the hippocampus (HC), a structure related to several cognitive functions, has shown to be particularly susceptible to the effects of noise. Human and animal studies have demonstrated that exposure to noise can generate different HC-related alterations, including morphological, functional and behavioral changes (Molina et al. 2016b, 2019; Nadhimi and Llano 2020). Unfortunately, little is known about the mechanisms involved in noise-induced hippocampal damage and more research is needed to understand how the different alterations are caused. In addition, considering that noise exposure constitutes a public health problem that is increasing in urbanized societies, accurate knowledge of these mechanisms has clinical relevance as it can lead to develop preventive strategies. In this perspective, the possible mechanisms involved in noise-induced hippocampal cell damage will be discussed, as well as the pathways through which these mechanisms could be triggered by noise exposure.Fil: Molina, Sonia Jazmín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; ArgentinaFil: Guelman, Laura Ruth. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; ArgentinaShenyang Editorial Dept Neural Regeneration Res2021-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/178737Molina, Sonia Jazmín; Guelman, Laura Ruth; Noise-induced hippocampal damage: potential mechanisms; Shenyang Editorial Dept Neural Regeneration Res; Neural Regeneration Research; 17; 3; 7-2021; 563-5641673-5374CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.4103/1673-5374.320982info:eu-repo/semantics/altIdentifier/url/https://journals.lww.com/nrronline/Fulltext/2022/03000/Noise_induced_hippocampal_damage__potential.19.aspxinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:26:02Zoai:ri.conicet.gov.ar:11336/178737instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:26:02.414CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Noise-induced hippocampal damage: potential mechanisms
title Noise-induced hippocampal damage: potential mechanisms
spellingShingle Noise-induced hippocampal damage: potential mechanisms
Molina, Sonia Jazmín
Noise
Hippocampus
stress
damage
title_short Noise-induced hippocampal damage: potential mechanisms
title_full Noise-induced hippocampal damage: potential mechanisms
title_fullStr Noise-induced hippocampal damage: potential mechanisms
title_full_unstemmed Noise-induced hippocampal damage: potential mechanisms
title_sort Noise-induced hippocampal damage: potential mechanisms
dc.creator.none.fl_str_mv Molina, Sonia Jazmín
Guelman, Laura Ruth
author Molina, Sonia Jazmín
author_facet Molina, Sonia Jazmín
Guelman, Laura Ruth
author_role author
author2 Guelman, Laura Ruth
author2_role author
dc.subject.none.fl_str_mv Noise
Hippocampus
stress
damage
topic Noise
Hippocampus
stress
damage
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Exposure to noise of high intensities (>80 dB) is considered a stressful event and might produce both auditory and extra-auditory damage, including different central nervous system (CNS) injuries. Within the CNS, the hippocampus (HC), a structure related to several cognitive functions, has shown to be particularly susceptible to the effects of noise. Human and animal studies have demonstrated that exposure to noise can generate different HC-related alterations, including morphological, functional and behavioral changes (Molina et al. 2016b, 2019; Nadhimi and Llano 2020). Unfortunately, little is known about the mechanisms involved in noise-induced hippocampal damage and more research is needed to understand how the different alterations are caused. In addition, considering that noise exposure constitutes a public health problem that is increasing in urbanized societies, accurate knowledge of these mechanisms has clinical relevance as it can lead to develop preventive strategies. In this perspective, the possible mechanisms involved in noise-induced hippocampal cell damage will be discussed, as well as the pathways through which these mechanisms could be triggered by noise exposure.
Fil: Molina, Sonia Jazmín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; Argentina
Fil: Guelman, Laura Ruth. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; Argentina
description Exposure to noise of high intensities (>80 dB) is considered a stressful event and might produce both auditory and extra-auditory damage, including different central nervous system (CNS) injuries. Within the CNS, the hippocampus (HC), a structure related to several cognitive functions, has shown to be particularly susceptible to the effects of noise. Human and animal studies have demonstrated that exposure to noise can generate different HC-related alterations, including morphological, functional and behavioral changes (Molina et al. 2016b, 2019; Nadhimi and Llano 2020). Unfortunately, little is known about the mechanisms involved in noise-induced hippocampal damage and more research is needed to understand how the different alterations are caused. In addition, considering that noise exposure constitutes a public health problem that is increasing in urbanized societies, accurate knowledge of these mechanisms has clinical relevance as it can lead to develop preventive strategies. In this perspective, the possible mechanisms involved in noise-induced hippocampal cell damage will be discussed, as well as the pathways through which these mechanisms could be triggered by noise exposure.
publishDate 2021
dc.date.none.fl_str_mv 2021-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/178737
Molina, Sonia Jazmín; Guelman, Laura Ruth; Noise-induced hippocampal damage: potential mechanisms; Shenyang Editorial Dept Neural Regeneration Res; Neural Regeneration Research; 17; 3; 7-2021; 563-564
1673-5374
CONICET Digital
CONICET
url http://hdl.handle.net/11336/178737
identifier_str_mv Molina, Sonia Jazmín; Guelman, Laura Ruth; Noise-induced hippocampal damage: potential mechanisms; Shenyang Editorial Dept Neural Regeneration Res; Neural Regeneration Research; 17; 3; 7-2021; 563-564
1673-5374
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.4103/1673-5374.320982
info:eu-repo/semantics/altIdentifier/url/https://journals.lww.com/nrronline/Fulltext/2022/03000/Noise_induced_hippocampal_damage__potential.19.aspx
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Shenyang Editorial Dept Neural Regeneration Res
publisher.none.fl_str_mv Shenyang Editorial Dept Neural Regeneration Res
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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