Pituitary pars intermedia of male viscacha (lagostomus maximus maximus): A morphometric study of seasonal and age-related changes in immunohistochemistry

Autores
Acosta, Mariano; Mohamed, Fabian Heber
Año de publicación
2009
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The aim of this work was to study the pituitary pars intermedia in seasonally captured adult male and immature viscachas by immunohistochemistry and image analysis. The pituitary pars intermedia exhibited a well-developed parenchyma with scarce connective tissue and vascularization. It was formed by a close association of melanotrophs and folliculostellate cells. The folliculostellate cells were stellate in shape with cytoplasmic processes, and they originated follicles with PAS-positive colloid inside. The morphometric parameters of melanotrophs, follicular colloid and folliculostellate cells (S-100-ir and GFAP-ir) varied seasonally and in relation to age. These parameters showed minimal values in the adult males captured in winter and in immature animals, and they were maximal in summer. The percentage of vimentin-positive area of the folliculostellate cells was maximal in immature animals, decreased in relation to age and did not vary seasonally in the adult animals. The greatest development of pars intermedia in the adult animals in relation to the immature ones is probably related to the adults' adaptation to the semiarid environment. The expression of the tested proteins suggests a probable neuroectodermic origin for the folliculostellate cells of the viscacha pituitary pars intermedia. In addition, the cytoplasmic processes of folliculostellate cells might originate an intercellular communication network inside the pars intermedia. The decrease in the morphometric parameters melanotrophs, follicular colloid and folliculostellate cells in winter suggests a low endocrine activity of this zone. This fact might be due to the effect of the short photoperiod and high melatonin serum levels.
Fil: Acosta, Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Mohamed, Fabian Heber. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Materia
AGE
IMMUNOHISTOCHEMISTRY
LAGOSTOMUS
PITUITARY PARS INTERMEDIA
SEASON
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/93232
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/93232
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Pituitary pars intermedia of male viscacha (lagostomus maximus maximus): A morphometric study of seasonal and age-related changes in immunohistochemistryAcosta, MarianoMohamed, Fabian HeberAGEIMMUNOHISTOCHEMISTRYLAGOSTOMUSPITUITARY PARS INTERMEDIASEASONhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The aim of this work was to study the pituitary pars intermedia in seasonally captured adult male and immature viscachas by immunohistochemistry and image analysis. The pituitary pars intermedia exhibited a well-developed parenchyma with scarce connective tissue and vascularization. It was formed by a close association of melanotrophs and folliculostellate cells. The folliculostellate cells were stellate in shape with cytoplasmic processes, and they originated follicles with PAS-positive colloid inside. The morphometric parameters of melanotrophs, follicular colloid and folliculostellate cells (S-100-ir and GFAP-ir) varied seasonally and in relation to age. These parameters showed minimal values in the adult males captured in winter and in immature animals, and they were maximal in summer. The percentage of vimentin-positive area of the folliculostellate cells was maximal in immature animals, decreased in relation to age and did not vary seasonally in the adult animals. The greatest development of pars intermedia in the adult animals in relation to the immature ones is probably related to the adults' adaptation to the semiarid environment. The expression of the tested proteins suggests a probable neuroectodermic origin for the folliculostellate cells of the viscacha pituitary pars intermedia. In addition, the cytoplasmic processes of folliculostellate cells might originate an intercellular communication network inside the pars intermedia. The decrease in the morphometric parameters melanotrophs, follicular colloid and folliculostellate cells in winter suggests a low endocrine activity of this zone. This fact might be due to the effect of the short photoperiod and high melatonin serum levels.Fil: Acosta, Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; ArgentinaFil: Mohamed, Fabian Heber. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; ArgentinaKarger2009-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/93232Acosta, Mariano; Mohamed, Fabian Heber; Pituitary pars intermedia of male viscacha (lagostomus maximus maximus): A morphometric study of seasonal and age-related changes in immunohistochemistry; Karger; Cells Tissues Organs; 190; 4; 9-2009; 219-2291422-6405CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.karger.com/Article/Abstract/204751info:eu-repo/semantics/altIdentifier/doi/10.1159/000204751info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-17T10:59:38Zoai:ri.conicet.gov.ar:11336/93232instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-17 10:59:38.347CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Pituitary pars intermedia of male viscacha (lagostomus maximus maximus): A morphometric study of seasonal and age-related changes in immunohistochemistry
title Pituitary pars intermedia of male viscacha (lagostomus maximus maximus): A morphometric study of seasonal and age-related changes in immunohistochemistry
spellingShingle Pituitary pars intermedia of male viscacha (lagostomus maximus maximus): A morphometric study of seasonal and age-related changes in immunohistochemistry
Acosta, Mariano
AGE
IMMUNOHISTOCHEMISTRY
LAGOSTOMUS
PITUITARY PARS INTERMEDIA
SEASON
title_short Pituitary pars intermedia of male viscacha (lagostomus maximus maximus): A morphometric study of seasonal and age-related changes in immunohistochemistry
title_full Pituitary pars intermedia of male viscacha (lagostomus maximus maximus): A morphometric study of seasonal and age-related changes in immunohistochemistry
title_fullStr Pituitary pars intermedia of male viscacha (lagostomus maximus maximus): A morphometric study of seasonal and age-related changes in immunohistochemistry
title_full_unstemmed Pituitary pars intermedia of male viscacha (lagostomus maximus maximus): A morphometric study of seasonal and age-related changes in immunohistochemistry
title_sort Pituitary pars intermedia of male viscacha (lagostomus maximus maximus): A morphometric study of seasonal and age-related changes in immunohistochemistry
dc.creator.none.fl_str_mv Acosta, Mariano
Mohamed, Fabian Heber
author Acosta, Mariano
author_facet Acosta, Mariano
Mohamed, Fabian Heber
author_role author
author2 Mohamed, Fabian Heber
author2_role author
dc.subject.none.fl_str_mv AGE
IMMUNOHISTOCHEMISTRY
LAGOSTOMUS
PITUITARY PARS INTERMEDIA
SEASON
topic AGE
IMMUNOHISTOCHEMISTRY
LAGOSTOMUS
PITUITARY PARS INTERMEDIA
SEASON
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The aim of this work was to study the pituitary pars intermedia in seasonally captured adult male and immature viscachas by immunohistochemistry and image analysis. The pituitary pars intermedia exhibited a well-developed parenchyma with scarce connective tissue and vascularization. It was formed by a close association of melanotrophs and folliculostellate cells. The folliculostellate cells were stellate in shape with cytoplasmic processes, and they originated follicles with PAS-positive colloid inside. The morphometric parameters of melanotrophs, follicular colloid and folliculostellate cells (S-100-ir and GFAP-ir) varied seasonally and in relation to age. These parameters showed minimal values in the adult males captured in winter and in immature animals, and they were maximal in summer. The percentage of vimentin-positive area of the folliculostellate cells was maximal in immature animals, decreased in relation to age and did not vary seasonally in the adult animals. The greatest development of pars intermedia in the adult animals in relation to the immature ones is probably related to the adults' adaptation to the semiarid environment. The expression of the tested proteins suggests a probable neuroectodermic origin for the folliculostellate cells of the viscacha pituitary pars intermedia. In addition, the cytoplasmic processes of folliculostellate cells might originate an intercellular communication network inside the pars intermedia. The decrease in the morphometric parameters melanotrophs, follicular colloid and folliculostellate cells in winter suggests a low endocrine activity of this zone. This fact might be due to the effect of the short photoperiod and high melatonin serum levels.
Fil: Acosta, Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Mohamed, Fabian Heber. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
description The aim of this work was to study the pituitary pars intermedia in seasonally captured adult male and immature viscachas by immunohistochemistry and image analysis. The pituitary pars intermedia exhibited a well-developed parenchyma with scarce connective tissue and vascularization. It was formed by a close association of melanotrophs and folliculostellate cells. The folliculostellate cells were stellate in shape with cytoplasmic processes, and they originated follicles with PAS-positive colloid inside. The morphometric parameters of melanotrophs, follicular colloid and folliculostellate cells (S-100-ir and GFAP-ir) varied seasonally and in relation to age. These parameters showed minimal values in the adult males captured in winter and in immature animals, and they were maximal in summer. The percentage of vimentin-positive area of the folliculostellate cells was maximal in immature animals, decreased in relation to age and did not vary seasonally in the adult animals. The greatest development of pars intermedia in the adult animals in relation to the immature ones is probably related to the adults' adaptation to the semiarid environment. The expression of the tested proteins suggests a probable neuroectodermic origin for the folliculostellate cells of the viscacha pituitary pars intermedia. In addition, the cytoplasmic processes of folliculostellate cells might originate an intercellular communication network inside the pars intermedia. The decrease in the morphometric parameters melanotrophs, follicular colloid and folliculostellate cells in winter suggests a low endocrine activity of this zone. This fact might be due to the effect of the short photoperiod and high melatonin serum levels.
publishDate 2009
dc.date.none.fl_str_mv 2009-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/93232
Acosta, Mariano; Mohamed, Fabian Heber; Pituitary pars intermedia of male viscacha (lagostomus maximus maximus): A morphometric study of seasonal and age-related changes in immunohistochemistry; Karger; Cells Tissues Organs; 190; 4; 9-2009; 219-229
1422-6405
CONICET Digital
CONICET
url http://hdl.handle.net/11336/93232
identifier_str_mv Acosta, Mariano; Mohamed, Fabian Heber; Pituitary pars intermedia of male viscacha (lagostomus maximus maximus): A morphometric study of seasonal and age-related changes in immunohistochemistry; Karger; Cells Tissues Organs; 190; 4; 9-2009; 219-229
1422-6405
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.karger.com/Article/Abstract/204751
info:eu-repo/semantics/altIdentifier/doi/10.1159/000204751
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Karger
publisher.none.fl_str_mv Karger
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.001348

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