Immunohistochemical Study of Somatotrophs in Pituitary Pars Distalis of Male Viscacha (Lagostomus maximus maximus) in Relation to the Gonadal Activity

Autores
Filippa, Veronica Palmira; Mohamed, Fabian Heber
Año de publicación
2007
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Somatotrophs were identified and quantified in pituitary pars distalis of male viscachas (Lagostomus maximus maximus) during the annual reproductive cycle, after the administration of melatonin, after castration and in different growth stages by immunohistochemistry and morphometric analysis. In adult male viscachas, the somatotrophs were distributed throughout the pars distalis during the reproductive cycle. They were oval, pyramidal or round in shape with a large round nucleus. The percentage immunopositive area, the major cellular diameter and the number of cells decreased during the gonadal regression period in relation to the values found in the reproductive period. The administration of melatonin did not provoke any variations of the morphometric parameters studied. On the contrary, a significant decrease in the percentage immunopositive area, in the major cellular diameter and in the number of somatotrophs in castrated viscachas was observed. The study of different growth stages showed that these morphometric parameters increased from immature to adult animals in the reproductive period. The results obtained suggested that the variations of the morphometric parameters of somatotrophs are more related to the gonadal development and activity than to a direct effect of melatonin.
Fil: Filippa, Veronica Palmira. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; Argentina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; Argentina
Fil: Mohamed, Fabian Heber. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; Argentina
Materia
LAGOSTOMUS
PITUITARY
SOMATOTROPHS
GONADAL
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/158402
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Immunohistochemical Study of Somatotrophs in Pituitary Pars Distalis of Male Viscacha (Lagostomus maximus maximus) in Relation to the Gonadal ActivityFilippa, Veronica PalmiraMohamed, Fabian HeberLAGOSTOMUSPITUITARYSOMATOTROPHSGONADALhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Somatotrophs were identified and quantified in pituitary pars distalis of male viscachas (Lagostomus maximus maximus) during the annual reproductive cycle, after the administration of melatonin, after castration and in different growth stages by immunohistochemistry and morphometric analysis. In adult male viscachas, the somatotrophs were distributed throughout the pars distalis during the reproductive cycle. They were oval, pyramidal or round in shape with a large round nucleus. The percentage immunopositive area, the major cellular diameter and the number of cells decreased during the gonadal regression period in relation to the values found in the reproductive period. The administration of melatonin did not provoke any variations of the morphometric parameters studied. On the contrary, a significant decrease in the percentage immunopositive area, in the major cellular diameter and in the number of somatotrophs in castrated viscachas was observed. The study of different growth stages showed that these morphometric parameters increased from immature to adult animals in the reproductive period. The results obtained suggested that the variations of the morphometric parameters of somatotrophs are more related to the gonadal development and activity than to a direct effect of melatonin.Fil: Filippa, Veronica Palmira. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; Argentina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; ArgentinaFil: Mohamed, Fabian Heber. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; ArgentinaKarger2007-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/158402Filippa, Veronica Palmira; Mohamed, Fabian Heber; Immunohistochemical Study of Somatotrophs in Pituitary Pars Distalis of Male Viscacha (Lagostomus maximus maximus) in Relation to the Gonadal Activity; Karger; Cells Tissues Organs; 184; 3-4; 4-2007; 188-1971422-6405CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1159/000099626info:eu-repo/semantics/altIdentifier/url/https://www.karger.com/Article/Abstract/99626info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:43:43Zoai:ri.conicet.gov.ar:11336/158402instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:43:43.769CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Immunohistochemical Study of Somatotrophs in Pituitary Pars Distalis of Male Viscacha (Lagostomus maximus maximus) in Relation to the Gonadal Activity
title Immunohistochemical Study of Somatotrophs in Pituitary Pars Distalis of Male Viscacha (Lagostomus maximus maximus) in Relation to the Gonadal Activity
spellingShingle Immunohistochemical Study of Somatotrophs in Pituitary Pars Distalis of Male Viscacha (Lagostomus maximus maximus) in Relation to the Gonadal Activity
Filippa, Veronica Palmira
LAGOSTOMUS
PITUITARY
SOMATOTROPHS
GONADAL
title_short Immunohistochemical Study of Somatotrophs in Pituitary Pars Distalis of Male Viscacha (Lagostomus maximus maximus) in Relation to the Gonadal Activity
title_full Immunohistochemical Study of Somatotrophs in Pituitary Pars Distalis of Male Viscacha (Lagostomus maximus maximus) in Relation to the Gonadal Activity
title_fullStr Immunohistochemical Study of Somatotrophs in Pituitary Pars Distalis of Male Viscacha (Lagostomus maximus maximus) in Relation to the Gonadal Activity
title_full_unstemmed Immunohistochemical Study of Somatotrophs in Pituitary Pars Distalis of Male Viscacha (Lagostomus maximus maximus) in Relation to the Gonadal Activity
title_sort Immunohistochemical Study of Somatotrophs in Pituitary Pars Distalis of Male Viscacha (Lagostomus maximus maximus) in Relation to the Gonadal Activity
dc.creator.none.fl_str_mv Filippa, Veronica Palmira
Mohamed, Fabian Heber
author Filippa, Veronica Palmira
author_facet Filippa, Veronica Palmira
Mohamed, Fabian Heber
author_role author
author2 Mohamed, Fabian Heber
author2_role author
dc.subject.none.fl_str_mv LAGOSTOMUS
PITUITARY
SOMATOTROPHS
GONADAL
topic LAGOSTOMUS
PITUITARY
SOMATOTROPHS
GONADAL
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Somatotrophs were identified and quantified in pituitary pars distalis of male viscachas (Lagostomus maximus maximus) during the annual reproductive cycle, after the administration of melatonin, after castration and in different growth stages by immunohistochemistry and morphometric analysis. In adult male viscachas, the somatotrophs were distributed throughout the pars distalis during the reproductive cycle. They were oval, pyramidal or round in shape with a large round nucleus. The percentage immunopositive area, the major cellular diameter and the number of cells decreased during the gonadal regression period in relation to the values found in the reproductive period. The administration of melatonin did not provoke any variations of the morphometric parameters studied. On the contrary, a significant decrease in the percentage immunopositive area, in the major cellular diameter and in the number of somatotrophs in castrated viscachas was observed. The study of different growth stages showed that these morphometric parameters increased from immature to adult animals in the reproductive period. The results obtained suggested that the variations of the morphometric parameters of somatotrophs are more related to the gonadal development and activity than to a direct effect of melatonin.
Fil: Filippa, Veronica Palmira. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; Argentina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; Argentina
Fil: Mohamed, Fabian Heber. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; Argentina
description Somatotrophs were identified and quantified in pituitary pars distalis of male viscachas (Lagostomus maximus maximus) during the annual reproductive cycle, after the administration of melatonin, after castration and in different growth stages by immunohistochemistry and morphometric analysis. In adult male viscachas, the somatotrophs were distributed throughout the pars distalis during the reproductive cycle. They were oval, pyramidal or round in shape with a large round nucleus. The percentage immunopositive area, the major cellular diameter and the number of cells decreased during the gonadal regression period in relation to the values found in the reproductive period. The administration of melatonin did not provoke any variations of the morphometric parameters studied. On the contrary, a significant decrease in the percentage immunopositive area, in the major cellular diameter and in the number of somatotrophs in castrated viscachas was observed. The study of different growth stages showed that these morphometric parameters increased from immature to adult animals in the reproductive period. The results obtained suggested that the variations of the morphometric parameters of somatotrophs are more related to the gonadal development and activity than to a direct effect of melatonin.
publishDate 2007
dc.date.none.fl_str_mv 2007-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/158402
Filippa, Veronica Palmira; Mohamed, Fabian Heber; Immunohistochemical Study of Somatotrophs in Pituitary Pars Distalis of Male Viscacha (Lagostomus maximus maximus) in Relation to the Gonadal Activity; Karger; Cells Tissues Organs; 184; 3-4; 4-2007; 188-197
1422-6405
CONICET Digital
CONICET
url http://hdl.handle.net/11336/158402
identifier_str_mv Filippa, Veronica Palmira; Mohamed, Fabian Heber; Immunohistochemical Study of Somatotrophs in Pituitary Pars Distalis of Male Viscacha (Lagostomus maximus maximus) in Relation to the Gonadal Activity; Karger; Cells Tissues Organs; 184; 3-4; 4-2007; 188-197
1422-6405
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1159/000099626
info:eu-repo/semantics/altIdentifier/url/https://www.karger.com/Article/Abstract/99626
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Karger
publisher.none.fl_str_mv Karger
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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