Geographic variation of Trypanosoma cruzi Discrete Typing Units from the main vector Triatoma infestans at different scales

Autores
Fernandez, Maria del Pilar; Cecere, Maria Carla; Lanati, Leonardo Alejandro; Lauricella, Marta Alicia; Schijman, Alejandro Gabriel; Gurtler, Ricardo Esteban; Cardinal, Marta Victoria
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
tWe assessed the diversity and distribution of Trypanosoma cruzi discrete typing units (DTU) in Triatomainfestans populations and its association with local vector-borne transmission levels at various geographicscales. At a local scale, we found high predominance (92.4%) of TcVI over TcV in 68 microscope-positiveT. infestans collected in rural communities in Santiago del Estero province in northern Argentina. TcVwas more often found in communities with higher house infestation prevalence compatible with activevector-borne transmission. Humans and dogs were the main bloodmeal sources of the TcV- and TcVI-infected bugs. At a broader scale, the greatest variation in DTU diversity was found within the ArgentineChaco (227 microscope-positive bugs), mainly related to differences in equitability between TcVI and TcVamong study areas. At a country-wide level, a meta-analysis of published data revealed clear geographicvariations in the distribution of DTUs across countries. A correspondence analysis showed that DTUdistributions in domestic T. infestans were more similar within Argentina (dominated by TcVI) and withinBolivia (where TcI and TcV had similar relative frequencies), whereas large heterogeneity was foundwithin Chile. DTU diversity was lower in the western Argentine Chaco region and Paraguay (D = 0.14?0.22)than in the eastern Argentine Chaco, Bolivia and Chile (D = 0.20?0.68). Simultaneous DTU identificationsof T. cruzi-infected hosts and triatomines across areas differing in epidemiological status are needed toshed new light on the structure and dynamics of parasite transmission cycles.
Fil: Fernandez, Maria del Pilar. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Cecere, Maria Carla. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Lanati, Leonardo Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Lauricella, Marta Alicia. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; Argentina
Fil: Schijman, Alejandro Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular; Argentina
Fil: Gurtler, Ricardo Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Cardinal, Marta Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Materia
Trypanosoma Cruzi
Discrete Typing Units
Triatoma Infestans
Molecular Epidemiology
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/4332
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/4332
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Geographic variation of Trypanosoma cruzi Discrete Typing Units from the main vector Triatoma infestans at different scalesFernandez, Maria del PilarCecere, Maria CarlaLanati, Leonardo AlejandroLauricella, Marta AliciaSchijman, Alejandro GabrielGurtler, Ricardo EstebanCardinal, Marta VictoriaTrypanosoma CruziDiscrete Typing UnitsTriatoma InfestansMolecular Epidemiologyhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1tWe assessed the diversity and distribution of Trypanosoma cruzi discrete typing units (DTU) in Triatomainfestans populations and its association with local vector-borne transmission levels at various geographicscales. At a local scale, we found high predominance (92.4%) of TcVI over TcV in 68 microscope-positiveT. infestans collected in rural communities in Santiago del Estero province in northern Argentina. TcVwas more often found in communities with higher house infestation prevalence compatible with activevector-borne transmission. Humans and dogs were the main bloodmeal sources of the TcV- and TcVI-infected bugs. At a broader scale, the greatest variation in DTU diversity was found within the ArgentineChaco (227 microscope-positive bugs), mainly related to differences in equitability between TcVI and TcVamong study areas. At a country-wide level, a meta-analysis of published data revealed clear geographicvariations in the distribution of DTUs across countries. A correspondence analysis showed that DTUdistributions in domestic T. infestans were more similar within Argentina (dominated by TcVI) and withinBolivia (where TcI and TcV had similar relative frequencies), whereas large heterogeneity was foundwithin Chile. DTU diversity was lower in the western Argentine Chaco region and Paraguay (D = 0.14?0.22)than in the eastern Argentine Chaco, Bolivia and Chile (D = 0.20?0.68). Simultaneous DTU identificationsof T. cruzi-infected hosts and triatomines across areas differing in epidemiological status are needed toshed new light on the structure and dynamics of parasite transmission cycles.Fil: Fernandez, Maria del Pilar. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; ArgentinaFil: Cecere, Maria Carla. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; ArgentinaFil: Lanati, Leonardo Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; ArgentinaFil: Lauricella, Marta Alicia. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; ArgentinaFil: Schijman, Alejandro Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular; ArgentinaFil: Gurtler, Ricardo Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; ArgentinaFil: Cardinal, Marta Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; ArgentinaElsevier2014-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/4332Fernandez, Maria del Pilar; Cecere, Maria Carla; Lanati, Leonardo Alejandro; Lauricella, Marta Alicia; Schijman, Alejandro Gabriel; et al.; Geographic variation of Trypanosoma cruzi Discrete Typing Units from the main vector Triatoma infestans at different scales; Elsevier; Acta Tropica; 140; 1-8-2014; 10-180001-706Xenginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0001706X14002496info:eu-repo/semantics/altIdentifier/doi/10.1016/j.actatropica.2014.07.014info:eu-repo/semantics/altIdentifier/issn/0001-706Xinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:35:12Zoai:ri.conicet.gov.ar:11336/4332instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:35:12.248CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Geographic variation of Trypanosoma cruzi Discrete Typing Units from the main vector Triatoma infestans at different scales
title Geographic variation of Trypanosoma cruzi Discrete Typing Units from the main vector Triatoma infestans at different scales
spellingShingle Geographic variation of Trypanosoma cruzi Discrete Typing Units from the main vector Triatoma infestans at different scales
Fernandez, Maria del Pilar
Trypanosoma Cruzi
Discrete Typing Units
Triatoma Infestans
Molecular Epidemiology
title_short Geographic variation of Trypanosoma cruzi Discrete Typing Units from the main vector Triatoma infestans at different scales
title_full Geographic variation of Trypanosoma cruzi Discrete Typing Units from the main vector Triatoma infestans at different scales
title_fullStr Geographic variation of Trypanosoma cruzi Discrete Typing Units from the main vector Triatoma infestans at different scales
title_full_unstemmed Geographic variation of Trypanosoma cruzi Discrete Typing Units from the main vector Triatoma infestans at different scales
title_sort Geographic variation of Trypanosoma cruzi Discrete Typing Units from the main vector Triatoma infestans at different scales
dc.creator.none.fl_str_mv Fernandez, Maria del Pilar
Cecere, Maria Carla
Lanati, Leonardo Alejandro
Lauricella, Marta Alicia
Schijman, Alejandro Gabriel
Gurtler, Ricardo Esteban
Cardinal, Marta Victoria
author Fernandez, Maria del Pilar
author_facet Fernandez, Maria del Pilar
Cecere, Maria Carla
Lanati, Leonardo Alejandro
Lauricella, Marta Alicia
Schijman, Alejandro Gabriel
Gurtler, Ricardo Esteban
Cardinal, Marta Victoria
author_role author
author2 Cecere, Maria Carla
Lanati, Leonardo Alejandro
Lauricella, Marta Alicia
Schijman, Alejandro Gabriel
Gurtler, Ricardo Esteban
Cardinal, Marta Victoria
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Trypanosoma Cruzi
Discrete Typing Units
Triatoma Infestans
Molecular Epidemiology
topic Trypanosoma Cruzi
Discrete Typing Units
Triatoma Infestans
Molecular Epidemiology
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv tWe assessed the diversity and distribution of Trypanosoma cruzi discrete typing units (DTU) in Triatomainfestans populations and its association with local vector-borne transmission levels at various geographicscales. At a local scale, we found high predominance (92.4%) of TcVI over TcV in 68 microscope-positiveT. infestans collected in rural communities in Santiago del Estero province in northern Argentina. TcVwas more often found in communities with higher house infestation prevalence compatible with activevector-borne transmission. Humans and dogs were the main bloodmeal sources of the TcV- and TcVI-infected bugs. At a broader scale, the greatest variation in DTU diversity was found within the ArgentineChaco (227 microscope-positive bugs), mainly related to differences in equitability between TcVI and TcVamong study areas. At a country-wide level, a meta-analysis of published data revealed clear geographicvariations in the distribution of DTUs across countries. A correspondence analysis showed that DTUdistributions in domestic T. infestans were more similar within Argentina (dominated by TcVI) and withinBolivia (where TcI and TcV had similar relative frequencies), whereas large heterogeneity was foundwithin Chile. DTU diversity was lower in the western Argentine Chaco region and Paraguay (D = 0.14?0.22)than in the eastern Argentine Chaco, Bolivia and Chile (D = 0.20?0.68). Simultaneous DTU identificationsof T. cruzi-infected hosts and triatomines across areas differing in epidemiological status are needed toshed new light on the structure and dynamics of parasite transmission cycles.
Fil: Fernandez, Maria del Pilar. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Cecere, Maria Carla. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Lanati, Leonardo Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Lauricella, Marta Alicia. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; Argentina
Fil: Schijman, Alejandro Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular; Argentina
Fil: Gurtler, Ricardo Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Cardinal, Marta Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
description tWe assessed the diversity and distribution of Trypanosoma cruzi discrete typing units (DTU) in Triatomainfestans populations and its association with local vector-borne transmission levels at various geographicscales. At a local scale, we found high predominance (92.4%) of TcVI over TcV in 68 microscope-positiveT. infestans collected in rural communities in Santiago del Estero province in northern Argentina. TcVwas more often found in communities with higher house infestation prevalence compatible with activevector-borne transmission. Humans and dogs were the main bloodmeal sources of the TcV- and TcVI-infected bugs. At a broader scale, the greatest variation in DTU diversity was found within the ArgentineChaco (227 microscope-positive bugs), mainly related to differences in equitability between TcVI and TcVamong study areas. At a country-wide level, a meta-analysis of published data revealed clear geographicvariations in the distribution of DTUs across countries. A correspondence analysis showed that DTUdistributions in domestic T. infestans were more similar within Argentina (dominated by TcVI) and withinBolivia (where TcI and TcV had similar relative frequencies), whereas large heterogeneity was foundwithin Chile. DTU diversity was lower in the western Argentine Chaco region and Paraguay (D = 0.14?0.22)than in the eastern Argentine Chaco, Bolivia and Chile (D = 0.20?0.68). Simultaneous DTU identificationsof T. cruzi-infected hosts and triatomines across areas differing in epidemiological status are needed toshed new light on the structure and dynamics of parasite transmission cycles.
publishDate 2014
dc.date.none.fl_str_mv 2014-08-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/4332
Fernandez, Maria del Pilar; Cecere, Maria Carla; Lanati, Leonardo Alejandro; Lauricella, Marta Alicia; Schijman, Alejandro Gabriel; et al.; Geographic variation of Trypanosoma cruzi Discrete Typing Units from the main vector Triatoma infestans at different scales; Elsevier; Acta Tropica; 140; 1-8-2014; 10-18
0001-706X
url http://hdl.handle.net/11336/4332
identifier_str_mv Fernandez, Maria del Pilar; Cecere, Maria Carla; Lanati, Leonardo Alejandro; Lauricella, Marta Alicia; Schijman, Alejandro Gabriel; et al.; Geographic variation of Trypanosoma cruzi Discrete Typing Units from the main vector Triatoma infestans at different scales; Elsevier; Acta Tropica; 140; 1-8-2014; 10-18
0001-706X
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0001706X14002496
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.actatropica.2014.07.014
info:eu-repo/semantics/altIdentifier/issn/0001-706X
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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