Substantial iodine volume load reduction in CT angiography with dual-energy imaging: insights from a pilot randomized study

Autores
Carrascosa, Patricia; Capunay, Carlos; Rodriguez Granillo, Gaston Alfredo; Deviggiano, Alejandro; Vallejos, Javier; Leipsic, Jonathon A.
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
We explored whether dual-energy computed tomography (DECT) can allow a significant reduction in iodinated contrast volume during computed tomography angiography (CTA) without hampering image quality or assessibility. We prospectively randomized patients clinically referred to CTA to single energy computed tomography (SECT) with full iodine volume load (group A), DECT with 50 % iodine volume load (group B), DECT with 40 % iodine volume load (group C), and DECT with 30 % iodine volume load (group D); and compared image quality and assessibility. Eighty patients were enrolled and prospectively randomized. The mean age was 61.7 ± 15.0 years and 56 (71 %) patients were male. The demographical characteristics, body mass index, or mean radiation dose did not differ between groups. Significant reductions in total contrast volume were achieved in groups B, C, and D; with mean administrated contrast volumes of 90.3 ± 10.1, 39.5 ± 4.6, 28.3 ± 6.5, and 23.9 ± 6.0 mL, respectively, in groups A to D (p < 0.0001). With regard to image quality, no significant decrease in the Likert scale was observed with reductions of up to 60 % of the contrast volume (groups B and C). DECT at 50–60 keV in association with up to 60 % iodine load reduction, allowed similar signal density, image noise, and signal to noise ratio that SECT imaging with full iodine load. In this pilot, prospective, randomized study, dual energy CTA with up to 60 % iodine volume load reduction provided similar image quality and assessibility than full iodine load with conventional SECT imaging.
Fil: Carrascosa, Patricia. Diagnostico Maipu; Argentina
Fil: Capunay, Carlos. Diagnostico Maipu; Argentina
Fil: Rodriguez Granillo, Gaston Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Diagnostico Maipu; Argentina
Fil: Deviggiano, Alejandro. Diagnostico Maipu; Argentina
Fil: Vallejos, Javier. Diagnostico Maipu; Argentina
Fil: Leipsic, Jonathon A.. St. Paul’s Hospital; Canadá
Materia
Computed Tomography
Contrast
Nephropathy
Spectral
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/50885
Acceder
id CONICETDig_0e83d21c5c808148b774cd377251622d
oai_identifier_str oai:ri.conicet.gov.ar:11336/50885
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Substantial iodine volume load reduction in CT angiography with dual-energy imaging: insights from a pilot randomized studyCarrascosa, PatriciaCapunay, CarlosRodriguez Granillo, Gaston AlfredoDeviggiano, AlejandroVallejos, JavierLeipsic, Jonathon A.Computed TomographyContrastNephropathySpectralhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3We explored whether dual-energy computed tomography (DECT) can allow a significant reduction in iodinated contrast volume during computed tomography angiography (CTA) without hampering image quality or assessibility. We prospectively randomized patients clinically referred to CTA to single energy computed tomography (SECT) with full iodine volume load (group A), DECT with 50 % iodine volume load (group B), DECT with 40 % iodine volume load (group C), and DECT with 30 % iodine volume load (group D); and compared image quality and assessibility. Eighty patients were enrolled and prospectively randomized. The mean age was 61.7 ± 15.0 years and 56 (71 %) patients were male. The demographical characteristics, body mass index, or mean radiation dose did not differ between groups. Significant reductions in total contrast volume were achieved in groups B, C, and D; with mean administrated contrast volumes of 90.3 ± 10.1, 39.5 ± 4.6, 28.3 ± 6.5, and 23.9 ± 6.0 mL, respectively, in groups A to D (p < 0.0001). With regard to image quality, no significant decrease in the Likert scale was observed with reductions of up to 60 % of the contrast volume (groups B and C). DECT at 50–60 keV in association with up to 60 % iodine load reduction, allowed similar signal density, image noise, and signal to noise ratio that SECT imaging with full iodine load. In this pilot, prospective, randomized study, dual energy CTA with up to 60 % iodine volume load reduction provided similar image quality and assessibility than full iodine load with conventional SECT imaging.Fil: Carrascosa, Patricia. Diagnostico Maipu; ArgentinaFil: Capunay, Carlos. Diagnostico Maipu; ArgentinaFil: Rodriguez Granillo, Gaston Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Diagnostico Maipu; ArgentinaFil: Deviggiano, Alejandro. Diagnostico Maipu; ArgentinaFil: Vallejos, Javier. Diagnostico Maipu; ArgentinaFil: Leipsic, Jonathon A.. St. Paul’s Hospital; CanadáSpringer2014-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/50885Carrascosa, Patricia; Capunay, Carlos; Rodriguez Granillo, Gaston Alfredo; Deviggiano, Alejandro; Vallejos, Javier; et al.; Substantial iodine volume load reduction in CT angiography with dual-energy imaging: insights from a pilot randomized study; Springer; International Journal Of Cardiovascular Imaging; 30; 8; 12-2014; 1613-16201569-5794CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1007/s10554-014-0501-1info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs10554-014-0501-1info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:47:01Zoai:ri.conicet.gov.ar:11336/50885instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:47:01.935CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Substantial iodine volume load reduction in CT angiography with dual-energy imaging: insights from a pilot randomized study
title Substantial iodine volume load reduction in CT angiography with dual-energy imaging: insights from a pilot randomized study
spellingShingle Substantial iodine volume load reduction in CT angiography with dual-energy imaging: insights from a pilot randomized study
Carrascosa, Patricia
Computed Tomography
Contrast
Nephropathy
Spectral
title_short Substantial iodine volume load reduction in CT angiography with dual-energy imaging: insights from a pilot randomized study
title_full Substantial iodine volume load reduction in CT angiography with dual-energy imaging: insights from a pilot randomized study
title_fullStr Substantial iodine volume load reduction in CT angiography with dual-energy imaging: insights from a pilot randomized study
title_full_unstemmed Substantial iodine volume load reduction in CT angiography with dual-energy imaging: insights from a pilot randomized study
title_sort Substantial iodine volume load reduction in CT angiography with dual-energy imaging: insights from a pilot randomized study
dc.creator.none.fl_str_mv Carrascosa, Patricia
Capunay, Carlos
Rodriguez Granillo, Gaston Alfredo
Deviggiano, Alejandro
Vallejos, Javier
Leipsic, Jonathon A.
author Carrascosa, Patricia
author_facet Carrascosa, Patricia
Capunay, Carlos
Rodriguez Granillo, Gaston Alfredo
Deviggiano, Alejandro
Vallejos, Javier
Leipsic, Jonathon A.
author_role author
author2 Capunay, Carlos
Rodriguez Granillo, Gaston Alfredo
Deviggiano, Alejandro
Vallejos, Javier
Leipsic, Jonathon A.
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Computed Tomography
Contrast
Nephropathy
Spectral
topic Computed Tomography
Contrast
Nephropathy
Spectral
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv We explored whether dual-energy computed tomography (DECT) can allow a significant reduction in iodinated contrast volume during computed tomography angiography (CTA) without hampering image quality or assessibility. We prospectively randomized patients clinically referred to CTA to single energy computed tomography (SECT) with full iodine volume load (group A), DECT with 50 % iodine volume load (group B), DECT with 40 % iodine volume load (group C), and DECT with 30 % iodine volume load (group D); and compared image quality and assessibility. Eighty patients were enrolled and prospectively randomized. The mean age was 61.7 ± 15.0 years and 56 (71 %) patients were male. The demographical characteristics, body mass index, or mean radiation dose did not differ between groups. Significant reductions in total contrast volume were achieved in groups B, C, and D; with mean administrated contrast volumes of 90.3 ± 10.1, 39.5 ± 4.6, 28.3 ± 6.5, and 23.9 ± 6.0 mL, respectively, in groups A to D (p < 0.0001). With regard to image quality, no significant decrease in the Likert scale was observed with reductions of up to 60 % of the contrast volume (groups B and C). DECT at 50–60 keV in association with up to 60 % iodine load reduction, allowed similar signal density, image noise, and signal to noise ratio that SECT imaging with full iodine load. In this pilot, prospective, randomized study, dual energy CTA with up to 60 % iodine volume load reduction provided similar image quality and assessibility than full iodine load with conventional SECT imaging.
Fil: Carrascosa, Patricia. Diagnostico Maipu; Argentina
Fil: Capunay, Carlos. Diagnostico Maipu; Argentina
Fil: Rodriguez Granillo, Gaston Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Diagnostico Maipu; Argentina
Fil: Deviggiano, Alejandro. Diagnostico Maipu; Argentina
Fil: Vallejos, Javier. Diagnostico Maipu; Argentina
Fil: Leipsic, Jonathon A.. St. Paul’s Hospital; Canadá
description We explored whether dual-energy computed tomography (DECT) can allow a significant reduction in iodinated contrast volume during computed tomography angiography (CTA) without hampering image quality or assessibility. We prospectively randomized patients clinically referred to CTA to single energy computed tomography (SECT) with full iodine volume load (group A), DECT with 50 % iodine volume load (group B), DECT with 40 % iodine volume load (group C), and DECT with 30 % iodine volume load (group D); and compared image quality and assessibility. Eighty patients were enrolled and prospectively randomized. The mean age was 61.7 ± 15.0 years and 56 (71 %) patients were male. The demographical characteristics, body mass index, or mean radiation dose did not differ between groups. Significant reductions in total contrast volume were achieved in groups B, C, and D; with mean administrated contrast volumes of 90.3 ± 10.1, 39.5 ± 4.6, 28.3 ± 6.5, and 23.9 ± 6.0 mL, respectively, in groups A to D (p < 0.0001). With regard to image quality, no significant decrease in the Likert scale was observed with reductions of up to 60 % of the contrast volume (groups B and C). DECT at 50–60 keV in association with up to 60 % iodine load reduction, allowed similar signal density, image noise, and signal to noise ratio that SECT imaging with full iodine load. In this pilot, prospective, randomized study, dual energy CTA with up to 60 % iodine volume load reduction provided similar image quality and assessibility than full iodine load with conventional SECT imaging.
publishDate 2014
dc.date.none.fl_str_mv 2014-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/50885
Carrascosa, Patricia; Capunay, Carlos; Rodriguez Granillo, Gaston Alfredo; Deviggiano, Alejandro; Vallejos, Javier; et al.; Substantial iodine volume load reduction in CT angiography with dual-energy imaging: insights from a pilot randomized study; Springer; International Journal Of Cardiovascular Imaging; 30; 8; 12-2014; 1613-1620
1569-5794
CONICET Digital
CONICET
url http://hdl.handle.net/11336/50885
identifier_str_mv Carrascosa, Patricia; Capunay, Carlos; Rodriguez Granillo, Gaston Alfredo; Deviggiano, Alejandro; Vallejos, Javier; et al.; Substantial iodine volume load reduction in CT angiography with dual-energy imaging: insights from a pilot randomized study; Springer; International Journal Of Cardiovascular Imaging; 30; 8; 12-2014; 1613-1620
1569-5794
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1007/s10554-014-0501-1
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs10554-014-0501-1
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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