Aedes aegypti from temperate regions of South America are highly competent to transmit dengue virus

Autores
Lourenço de Oliveira; Ricardo; Vega Rua, Anubis; Vezzani, Dario; Willat, Gabriela; Vazeille, Marie; Mousson, Laurence; Failloux, Anna Bella
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Aedes aegypti is extensively spread throughout South America where it has been responsible for large dengue epidemics during the last decades. Intriguingly, dengue transmission has not been reported in Uruguay and is essentially prevalent in subtropical northern Argentina which borders Uruguay. Methods: We assessed vector competence for dengue virus (DENV) of Ae. aegypti populations collected in subtropical Argentina (Corrientes) as well as temperate Uruguay (Salto) and Argentina (Buenos Aires) in 2012 using experimental oral infections with DENV-2. Mosquitoes were incubated at 28°C and examined at 14 and 21 days p.i. to access viral dissemination and transmission. Batches of the Buenos Aires mosquitoes were also incubated at 15°C and 20°C. Results: Although mosquitoes from temperate Uruguay and Argentina were competent to transmit DENV, those from subtropical Argentina were more susceptible, displaying the highest virus titters in the head and presenting the highest dissemination of infection and transmission efficiency rates when incubated at 28°C. Interestingly, infectious viral particles could be detected in saliva of mosquitoes from Buenos Aires exposed to 15°C and 20°C. Conclusions: There is a potential risk of establishing DENV transmission in Uruguay and for the spread of dengue outbreaks to other parts of subtropical and temperate Argentina, notably during spring and summer periods.
Fil: Lourenço de Oliveira; Ricardo. Instituto Pasteur; Francia. Fundación Oswaldo Cruz; Brasil
Fil: Vega Rua, Anubis. Instituto Pasteur; Francia
Fil: Vezzani, Dario. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Willat, Gabriela. No especifíca;
Fil: Vazeille, Marie. Instituto Pasteur; Francia
Fil: Mousson, Laurence. Instituto Pasteur; Francia
Fil: Failloux, Anna Bella. Instituto Pasteur; Francia
Materia
ARGENTINA
DENGUE
EXPERIMENTAL INFECTIONS
URUGUAY
VECTOR COMPETENCE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/2305
Acceder
id CONICETDig_0c4e992e2f9fc215b632e7cde9aafec9
oai_identifier_str oai:ri.conicet.gov.ar:11336/2305
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Aedes aegypti from temperate regions of South America are highly competent to transmit dengue virusLourenço de Oliveira; RicardoVega Rua, AnubisVezzani, DarioWillat, GabrielaVazeille, MarieMousson, LaurenceFailloux, Anna BellaARGENTINADENGUEEXPERIMENTAL INFECTIONSURUGUAYVECTOR COMPETENCEhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1https://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Background: Aedes aegypti is extensively spread throughout South America where it has been responsible for large dengue epidemics during the last decades. Intriguingly, dengue transmission has not been reported in Uruguay and is essentially prevalent in subtropical northern Argentina which borders Uruguay. Methods: We assessed vector competence for dengue virus (DENV) of Ae. aegypti populations collected in subtropical Argentina (Corrientes) as well as temperate Uruguay (Salto) and Argentina (Buenos Aires) in 2012 using experimental oral infections with DENV-2. Mosquitoes were incubated at 28°C and examined at 14 and 21 days p.i. to access viral dissemination and transmission. Batches of the Buenos Aires mosquitoes were also incubated at 15°C and 20°C. Results: Although mosquitoes from temperate Uruguay and Argentina were competent to transmit DENV, those from subtropical Argentina were more susceptible, displaying the highest virus titters in the head and presenting the highest dissemination of infection and transmission efficiency rates when incubated at 28°C. Interestingly, infectious viral particles could be detected in saliva of mosquitoes from Buenos Aires exposed to 15°C and 20°C. Conclusions: There is a potential risk of establishing DENV transmission in Uruguay and for the spread of dengue outbreaks to other parts of subtropical and temperate Argentina, notably during spring and summer periods.Fil: Lourenço de Oliveira; Ricardo. Instituto Pasteur; Francia. Fundación Oswaldo Cruz; BrasilFil: Vega Rua, Anubis. Instituto Pasteur; FranciaFil: Vezzani, Dario. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; ArgentinaFil: Willat, Gabriela. No especifíca;Fil: Vazeille, Marie. Instituto Pasteur; FranciaFil: Mousson, Laurence. Instituto Pasteur; FranciaFil: Failloux, Anna Bella. Instituto Pasteur; FranciaBiomed Central2013-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/2305Lourenço de Oliveira; Ricardo; Vega Rua, Anubis; Vezzani, Dario; Willat, Gabriela; Vazeille, Marie; et al.; Aedes aegypti from temperate regions of South America are highly competent to transmit dengue virus; Biomed Central; BMC Infectious Diseases; 13; 610; 12-2013; 1-81471-2334enginfo:eu-repo/semantics/altIdentifier/url/http://www.biomedcentral.com/1471-2334/13/610info:eu-repo/semantics/altIdentifier/url/http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929315/info:eu-repo/semantics/altIdentifier/doi/doi:10.1186/1471-2334-13-610info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:44:30Zoai:ri.conicet.gov.ar:11336/2305instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:44:30.468CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Aedes aegypti from temperate regions of South America are highly competent to transmit dengue virus
title Aedes aegypti from temperate regions of South America are highly competent to transmit dengue virus
spellingShingle Aedes aegypti from temperate regions of South America are highly competent to transmit dengue virus
Lourenço de Oliveira; Ricardo
ARGENTINA
DENGUE
EXPERIMENTAL INFECTIONS
URUGUAY
VECTOR COMPETENCE
title_short Aedes aegypti from temperate regions of South America are highly competent to transmit dengue virus
title_full Aedes aegypti from temperate regions of South America are highly competent to transmit dengue virus
title_fullStr Aedes aegypti from temperate regions of South America are highly competent to transmit dengue virus
title_full_unstemmed Aedes aegypti from temperate regions of South America are highly competent to transmit dengue virus
title_sort Aedes aegypti from temperate regions of South America are highly competent to transmit dengue virus
dc.creator.none.fl_str_mv Lourenço de Oliveira; Ricardo
Vega Rua, Anubis
Vezzani, Dario
Willat, Gabriela
Vazeille, Marie
Mousson, Laurence
Failloux, Anna Bella
author Lourenço de Oliveira; Ricardo
author_facet Lourenço de Oliveira; Ricardo
Vega Rua, Anubis
Vezzani, Dario
Willat, Gabriela
Vazeille, Marie
Mousson, Laurence
Failloux, Anna Bella
author_role author
author2 Vega Rua, Anubis
Vezzani, Dario
Willat, Gabriela
Vazeille, Marie
Mousson, Laurence
Failloux, Anna Bella
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv ARGENTINA
DENGUE
EXPERIMENTAL INFECTIONS
URUGUAY
VECTOR COMPETENCE
topic ARGENTINA
DENGUE
EXPERIMENTAL INFECTIONS
URUGUAY
VECTOR COMPETENCE
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Background: Aedes aegypti is extensively spread throughout South America where it has been responsible for large dengue epidemics during the last decades. Intriguingly, dengue transmission has not been reported in Uruguay and is essentially prevalent in subtropical northern Argentina which borders Uruguay. Methods: We assessed vector competence for dengue virus (DENV) of Ae. aegypti populations collected in subtropical Argentina (Corrientes) as well as temperate Uruguay (Salto) and Argentina (Buenos Aires) in 2012 using experimental oral infections with DENV-2. Mosquitoes were incubated at 28°C and examined at 14 and 21 days p.i. to access viral dissemination and transmission. Batches of the Buenos Aires mosquitoes were also incubated at 15°C and 20°C. Results: Although mosquitoes from temperate Uruguay and Argentina were competent to transmit DENV, those from subtropical Argentina were more susceptible, displaying the highest virus titters in the head and presenting the highest dissemination of infection and transmission efficiency rates when incubated at 28°C. Interestingly, infectious viral particles could be detected in saliva of mosquitoes from Buenos Aires exposed to 15°C and 20°C. Conclusions: There is a potential risk of establishing DENV transmission in Uruguay and for the spread of dengue outbreaks to other parts of subtropical and temperate Argentina, notably during spring and summer periods.
Fil: Lourenço de Oliveira; Ricardo. Instituto Pasteur; Francia. Fundación Oswaldo Cruz; Brasil
Fil: Vega Rua, Anubis. Instituto Pasteur; Francia
Fil: Vezzani, Dario. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Willat, Gabriela. No especifíca;
Fil: Vazeille, Marie. Instituto Pasteur; Francia
Fil: Mousson, Laurence. Instituto Pasteur; Francia
Fil: Failloux, Anna Bella. Instituto Pasteur; Francia
description Background: Aedes aegypti is extensively spread throughout South America where it has been responsible for large dengue epidemics during the last decades. Intriguingly, dengue transmission has not been reported in Uruguay and is essentially prevalent in subtropical northern Argentina which borders Uruguay. Methods: We assessed vector competence for dengue virus (DENV) of Ae. aegypti populations collected in subtropical Argentina (Corrientes) as well as temperate Uruguay (Salto) and Argentina (Buenos Aires) in 2012 using experimental oral infections with DENV-2. Mosquitoes were incubated at 28°C and examined at 14 and 21 days p.i. to access viral dissemination and transmission. Batches of the Buenos Aires mosquitoes were also incubated at 15°C and 20°C. Results: Although mosquitoes from temperate Uruguay and Argentina were competent to transmit DENV, those from subtropical Argentina were more susceptible, displaying the highest virus titters in the head and presenting the highest dissemination of infection and transmission efficiency rates when incubated at 28°C. Interestingly, infectious viral particles could be detected in saliva of mosquitoes from Buenos Aires exposed to 15°C and 20°C. Conclusions: There is a potential risk of establishing DENV transmission in Uruguay and for the spread of dengue outbreaks to other parts of subtropical and temperate Argentina, notably during spring and summer periods.
publishDate 2013
dc.date.none.fl_str_mv 2013-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/2305
Lourenço de Oliveira; Ricardo; Vega Rua, Anubis; Vezzani, Dario; Willat, Gabriela; Vazeille, Marie; et al.; Aedes aegypti from temperate regions of South America are highly competent to transmit dengue virus; Biomed Central; BMC Infectious Diseases; 13; 610; 12-2013; 1-8
1471-2334
url http://hdl.handle.net/11336/2305
identifier_str_mv Lourenço de Oliveira; Ricardo; Vega Rua, Anubis; Vezzani, Dario; Willat, Gabriela; Vazeille, Marie; et al.; Aedes aegypti from temperate regions of South America are highly competent to transmit dengue virus; Biomed Central; BMC Infectious Diseases; 13; 610; 12-2013; 1-8
1471-2334
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.biomedcentral.com/1471-2334/13/610
info:eu-repo/semantics/altIdentifier/url/http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929315/
info:eu-repo/semantics/altIdentifier/doi/doi:10.1186/1471-2334-13-610
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Biomed Central
publisher.none.fl_str_mv Biomed Central
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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