Serotype distribution of pneumococci isolated from pediatric patients with acute otitis media and invasive infections, and potential coverage of pneumococcal conjugated vaccines

Autores
Reijtman, Vanesa R; Fossati, Sofía; Hernández, Claudia; Sommerfleck, Patricia; Bernáldez, Patricia; Litterio, Mirta; Berberian, Griselda; Regueira, Mabel; Lopardo, Horacio
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Fil: Reijtman, Vanesa R. Servicio de Microbiología, Hospital de Pediatría, Ciudad Autónoma de Buenos Aires; Argentina.
Fil: Fossati, Sofía. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.
Fil: Hernández, Claudia. Servicio de Microbiología, Hospital de Pediatría, Ciudad Autónoma de Buenos Aires; Argentina.
Fil: Sommerfleck, Patricia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.
Fil: Bernáldez, Patricia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.
Fil: Litterio, Mirta. Servicio de Microbiología, Hospital de Pediatría, Ciudad Autónoma de Buenos Aires; Argentina.
Fil: Berberian, Griselda. Servicio de Control Epidemiológico e Infectología, Hospital de Pediatría “Prof. Dr. Juan P. Garrahan”; Argentina.
Fil: Regueira, Mabel. Servicio de Otorrinolaringología, Hospital de Pediatría, Ciudad Autónoma de Buenos Aires; Argentina.
Fil: Lopardo, Horacio. Servicio de Microbiología, Hospital de Pediatría, Ciudad Autónoma de Buenos Aires; Argentina.
A 16-month prospective, descriptive study was conducted on pneumococcal serotype distribution isolated from children with acute otitis media (AOM) and invasive infections (INV). Eighty-nine children with pneumococcal INV and 324 with a first episode of AOM were included. Bacterial pathogens (N = 326) were isolated from the middle-ear fluid of 250 patients. A total of 30 pneumococcal serotypes were identified. Prevalent serotypes were 14, 19A, 9V, 3, 19F, 6A, 23F, and 18C in AOM and 14, 1, 19A, 5, 12F, 6B, and 18C in INV. Potential coverage with PCV10 vaccine would be 46.5 % and 60.7 % for pneumococci involved in AOM and INV, respectively; it would be 71.7 % and 73 % with PCV13. PCV10, conjugated with a Haemophilus protein, would have an immunologic coverage of 39.9 % for AOM vs. 18.5 % with PCV13. However, differences in the prevention of INV were crucial for the decision to include the 13-valent vaccine in the national calendar for children less than two years old in Argentina.
Fuente
Revista Argentina de Microbiología 2013;45(1):27-33.
Materia
Otitis
Otitis Media
Streptococcus pneumoniae
Serogrupo
Nivel de accesibilidad
acceso abierto
Condiciones de uso
Repositorio
Sistema de Gestión del Conocimiento ANLIS MALBRÁN
Institución
Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
OAI Identificador
oai:sgc.anlis.gob.ar:123456789/1883
Acceder
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network_acronym_str SGCANLIS
repository_id_str a
network_name_str Sistema de Gestión del Conocimiento ANLIS MALBRÁN
spelling Serotype distribution of pneumococci isolated from pediatric patients with acute otitis media and invasive infections, and potential coverage of pneumococcal conjugated vaccinesReijtman, Vanesa RFossati, SofíaHernández, ClaudiaSommerfleck, PatriciaBernáldez, PatriciaLitterio, MirtaBerberian, GriseldaRegueira, MabelLopardo, HoracioOtitisOtitis MediaStreptococcus pneumoniaeSerogrupoFil: Reijtman, Vanesa R. Servicio de Microbiología, Hospital de Pediatría, Ciudad Autónoma de Buenos Aires; Argentina.Fil: Fossati, Sofía. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.Fil: Hernández, Claudia. Servicio de Microbiología, Hospital de Pediatría, Ciudad Autónoma de Buenos Aires; Argentina.Fil: Sommerfleck, Patricia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.Fil: Bernáldez, Patricia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.Fil: Litterio, Mirta. Servicio de Microbiología, Hospital de Pediatría, Ciudad Autónoma de Buenos Aires; Argentina.Fil: Berberian, Griselda. Servicio de Control Epidemiológico e Infectología, Hospital de Pediatría “Prof. Dr. Juan P. Garrahan”; Argentina.Fil: Regueira, Mabel. Servicio de Otorrinolaringología, Hospital de Pediatría, Ciudad Autónoma de Buenos Aires; Argentina.Fil: Lopardo, Horacio. Servicio de Microbiología, Hospital de Pediatría, Ciudad Autónoma de Buenos Aires; Argentina.A 16-month prospective, descriptive study was conducted on pneumococcal serotype distribution isolated from children with acute otitis media (AOM) and invasive infections (INV). Eighty-nine children with pneumococcal INV and 324 with a first episode of AOM were included. Bacterial pathogens (N = 326) were isolated from the middle-ear fluid of 250 patients. A total of 30 pneumococcal serotypes were identified. Prevalent serotypes were 14, 19A, 9V, 3, 19F, 6A, 23F, and 18C in AOM and 14, 1, 19A, 5, 12F, 6B, and 18C in INV. Potential coverage with PCV10 vaccine would be 46.5 % and 60.7 % for pneumococci involved in AOM and INV, respectively; it would be 71.7 % and 73 % with PCV13. PCV10, conjugated with a Haemophilus protein, would have an immunologic coverage of 39.9 % for AOM vs. 18.5 % with PCV13. However, differences in the prevention of INV were crucial for the decision to include the 13-valent vaccine in the national calendar for children less than two years old in Argentina.2013info:ar-repo/semantics/articuloinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdf0325-7541http://sgc.anlis.gob.ar/handle/123456789/1883Revista Argentina de Microbiología 2013;45(1):27-33.reponame:Sistema de Gestión del Conocimiento ANLIS MALBRÁNinstname:Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"instacron:ANLISRevista Argentina de microbiologiaenginfo:eu-repo/semantics/openAccess2025-10-16T10:11:44Zoai:sgc.anlis.gob.ar:123456789/1883Institucionalhttp://sgc.anlis.gob.ar/Organismo científico-tecnológicoNo correspondehttp://sgc.anlis.gob.ar/oai/biblioteca@anlis.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:a2025-10-16 10:11:45.086Sistema de Gestión del Conocimiento ANLIS MALBRÁN - Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"false
dc.title.none.fl_str_mv Serotype distribution of pneumococci isolated from pediatric patients with acute otitis media and invasive infections, and potential coverage of pneumococcal conjugated vaccines
title Serotype distribution of pneumococci isolated from pediatric patients with acute otitis media and invasive infections, and potential coverage of pneumococcal conjugated vaccines
spellingShingle Serotype distribution of pneumococci isolated from pediatric patients with acute otitis media and invasive infections, and potential coverage of pneumococcal conjugated vaccines
Reijtman, Vanesa R
Otitis
Otitis Media
Streptococcus pneumoniae
Serogrupo
title_short Serotype distribution of pneumococci isolated from pediatric patients with acute otitis media and invasive infections, and potential coverage of pneumococcal conjugated vaccines
title_full Serotype distribution of pneumococci isolated from pediatric patients with acute otitis media and invasive infections, and potential coverage of pneumococcal conjugated vaccines
title_fullStr Serotype distribution of pneumococci isolated from pediatric patients with acute otitis media and invasive infections, and potential coverage of pneumococcal conjugated vaccines
title_full_unstemmed Serotype distribution of pneumococci isolated from pediatric patients with acute otitis media and invasive infections, and potential coverage of pneumococcal conjugated vaccines
title_sort Serotype distribution of pneumococci isolated from pediatric patients with acute otitis media and invasive infections, and potential coverage of pneumococcal conjugated vaccines
dc.creator.none.fl_str_mv Reijtman, Vanesa R
Fossati, Sofía
Hernández, Claudia
Sommerfleck, Patricia
Bernáldez, Patricia
Litterio, Mirta
Berberian, Griselda
Regueira, Mabel
Lopardo, Horacio
author Reijtman, Vanesa R
author_facet Reijtman, Vanesa R
Fossati, Sofía
Hernández, Claudia
Sommerfleck, Patricia
Bernáldez, Patricia
Litterio, Mirta
Berberian, Griselda
Regueira, Mabel
Lopardo, Horacio
author_role author
author2 Fossati, Sofía
Hernández, Claudia
Sommerfleck, Patricia
Bernáldez, Patricia
Litterio, Mirta
Berberian, Griselda
Regueira, Mabel
Lopardo, Horacio
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Otitis
Otitis Media
Streptococcus pneumoniae
Serogrupo
topic Otitis
Otitis Media
Streptococcus pneumoniae
Serogrupo
dc.description.none.fl_txt_mv Fil: Reijtman, Vanesa R. Servicio de Microbiología, Hospital de Pediatría, Ciudad Autónoma de Buenos Aires; Argentina.
Fil: Fossati, Sofía. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.
Fil: Hernández, Claudia. Servicio de Microbiología, Hospital de Pediatría, Ciudad Autónoma de Buenos Aires; Argentina.
Fil: Sommerfleck, Patricia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.
Fil: Bernáldez, Patricia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.
Fil: Litterio, Mirta. Servicio de Microbiología, Hospital de Pediatría, Ciudad Autónoma de Buenos Aires; Argentina.
Fil: Berberian, Griselda. Servicio de Control Epidemiológico e Infectología, Hospital de Pediatría “Prof. Dr. Juan P. Garrahan”; Argentina.
Fil: Regueira, Mabel. Servicio de Otorrinolaringología, Hospital de Pediatría, Ciudad Autónoma de Buenos Aires; Argentina.
Fil: Lopardo, Horacio. Servicio de Microbiología, Hospital de Pediatría, Ciudad Autónoma de Buenos Aires; Argentina.
A 16-month prospective, descriptive study was conducted on pneumococcal serotype distribution isolated from children with acute otitis media (AOM) and invasive infections (INV). Eighty-nine children with pneumococcal INV and 324 with a first episode of AOM were included. Bacterial pathogens (N = 326) were isolated from the middle-ear fluid of 250 patients. A total of 30 pneumococcal serotypes were identified. Prevalent serotypes were 14, 19A, 9V, 3, 19F, 6A, 23F, and 18C in AOM and 14, 1, 19A, 5, 12F, 6B, and 18C in INV. Potential coverage with PCV10 vaccine would be 46.5 % and 60.7 % for pneumococci involved in AOM and INV, respectively; it would be 71.7 % and 73 % with PCV13. PCV10, conjugated with a Haemophilus protein, would have an immunologic coverage of 39.9 % for AOM vs. 18.5 % with PCV13. However, differences in the prevention of INV were crucial for the decision to include the 13-valent vaccine in the national calendar for children less than two years old in Argentina.
description Fil: Reijtman, Vanesa R. Servicio de Microbiología, Hospital de Pediatría, Ciudad Autónoma de Buenos Aires; Argentina.
publishDate 2013
dc.date.none.fl_str_mv 2013
dc.type.none.fl_str_mv info:ar-repo/semantics/articulo
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv 0325-7541
http://sgc.anlis.gob.ar/handle/123456789/1883
identifier_str_mv 0325-7541
url http://sgc.anlis.gob.ar/handle/123456789/1883
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Revista Argentina de microbiologia
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Revista Argentina de Microbiología 2013;45(1):27-33.
reponame:Sistema de Gestión del Conocimiento ANLIS MALBRÁN
instname:Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
instacron:ANLIS
reponame_str Sistema de Gestión del Conocimiento ANLIS MALBRÁN
collection Sistema de Gestión del Conocimiento ANLIS MALBRÁN
instname_str Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
instacron_str ANLIS
institution ANLIS
repository.name.fl_str_mv Sistema de Gestión del Conocimiento ANLIS MALBRÁN - Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
repository.mail.fl_str_mv biblioteca@anlis.gov.ar
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score 12.712165

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