Mitochondrial permeability transition in protozoan parasites: what we learned from Trypanosoma cruzi

Autores
Bustos, Patricia L.; Perrone, Alina E.; Milduberger, Natalia; Bua, Jacqueline
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Fil: Bustos, Patricia L. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología Dr. Mario Fatala Chaben; Argentina.
Fil: Perrone, Alina E. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología Dr. Mario Fatala Chaben; Argentina.
Fil: Milduberger, Natalia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología Dr. Mario Fatala Chaben; Argentina.
Fil: Bua, Jacqueline. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología Dr. Mario Fatala Chaben; Argentina.
Regulated cell death (RCD) involves a genetically encoded molecular machinery, which can be altered by means of pharmacologic and/or genetics interventions targeting the key components of such machinery. RCD often occurs in a delayed manner and is initiated in the context of adaptive responses that unsuccessfully attempt to restore cellular homeostasis. It is important to mention that the term RCD includes both physiological instances of death, referred to as ‘programmed cell death’, but also death processes that occur in pathological contexts. Our comprehension of cell death subroutines has progressed significantly, as the main molecular events underlying these mechanisms have been elucidated.
Fuente
Cell Death and Disease 2017;8:e3057
Materia
Enfermedad de Chagas
Proteínas de Transporte de Membrana Mitocondrial
Ciclosporina
Muerte Celular
Nivel de accesibilidad
acceso abierto
Condiciones de uso
Repositorio
Sistema de Gestión del Conocimiento ANLIS MALBRÁN
Institución
Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
OAI Identificador
oai:sgc.anlis.gob.ar:123456789/1442

id SGCANLIS_98bf9274d85161e709376b159b3d54d5
oai_identifier_str oai:sgc.anlis.gob.ar:123456789/1442
network_acronym_str SGCANLIS
repository_id_str a
network_name_str Sistema de Gestión del Conocimiento ANLIS MALBRÁN
spelling Mitochondrial permeability transition in protozoan parasites: what we learned from Trypanosoma cruziBustos, Patricia L.Perrone, Alina E.Milduberger, NataliaBua, JacquelineEnfermedad de ChagasProteínas de Transporte de Membrana MitocondrialCiclosporinaMuerte CelularFil: Bustos, Patricia L. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología Dr. Mario Fatala Chaben; Argentina.Fil: Perrone, Alina E. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología Dr. Mario Fatala Chaben; Argentina.Fil: Milduberger, Natalia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología Dr. Mario Fatala Chaben; Argentina.Fil: Bua, Jacqueline. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología Dr. Mario Fatala Chaben; Argentina.Regulated cell death (RCD) involves a genetically encoded molecular machinery, which can be altered by means of pharmacologic and/or genetics interventions targeting the key components of such machinery. RCD often occurs in a delayed manner and is initiated in the context of adaptive responses that unsuccessfully attempt to restore cellular homeostasis. It is important to mention that the term RCD includes both physiological instances of death, referred to as ‘programmed cell death’, but also death processes that occur in pathological contexts. Our comprehension of cell death subroutines has progressed significantly, as the main molecular events underlying these mechanisms have been elucidated.2017info:ar-repo/semantics/articuloinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdf2041-4889http://sgc.anlis.gob.ar/handle/123456789/144210.1038/cddis.2017.431Cell Death and Disease 2017;8:e3057reponame:Sistema de Gestión del Conocimiento ANLIS MALBRÁNinstname:Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"instacron:ANLISCell death & diseaseenginfo:eu-repo/semantics/openAccess2025-09-29T14:30:20Zoai:sgc.anlis.gob.ar:123456789/1442Institucionalhttp://sgc.anlis.gob.ar/Organismo científico-tecnológicoNo correspondehttp://sgc.anlis.gob.ar/oai/biblioteca@anlis.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:a2025-09-29 14:30:20.723Sistema de Gestión del Conocimiento ANLIS MALBRÁN - Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"false
dc.title.none.fl_str_mv Mitochondrial permeability transition in protozoan parasites: what we learned from Trypanosoma cruzi
title Mitochondrial permeability transition in protozoan parasites: what we learned from Trypanosoma cruzi
spellingShingle Mitochondrial permeability transition in protozoan parasites: what we learned from Trypanosoma cruzi
Bustos, Patricia L.
Enfermedad de Chagas
Proteínas de Transporte de Membrana Mitocondrial
Ciclosporina
Muerte Celular
title_short Mitochondrial permeability transition in protozoan parasites: what we learned from Trypanosoma cruzi
title_full Mitochondrial permeability transition in protozoan parasites: what we learned from Trypanosoma cruzi
title_fullStr Mitochondrial permeability transition in protozoan parasites: what we learned from Trypanosoma cruzi
title_full_unstemmed Mitochondrial permeability transition in protozoan parasites: what we learned from Trypanosoma cruzi
title_sort Mitochondrial permeability transition in protozoan parasites: what we learned from Trypanosoma cruzi
dc.creator.none.fl_str_mv Bustos, Patricia L.
Perrone, Alina E.
Milduberger, Natalia
Bua, Jacqueline
author Bustos, Patricia L.
author_facet Bustos, Patricia L.
Perrone, Alina E.
Milduberger, Natalia
Bua, Jacqueline
author_role author
author2 Perrone, Alina E.
Milduberger, Natalia
Bua, Jacqueline
author2_role author
author
author
dc.subject.none.fl_str_mv Enfermedad de Chagas
Proteínas de Transporte de Membrana Mitocondrial
Ciclosporina
Muerte Celular
topic Enfermedad de Chagas
Proteínas de Transporte de Membrana Mitocondrial
Ciclosporina
Muerte Celular
dc.description.none.fl_txt_mv Fil: Bustos, Patricia L. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología Dr. Mario Fatala Chaben; Argentina.
Fil: Perrone, Alina E. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología Dr. Mario Fatala Chaben; Argentina.
Fil: Milduberger, Natalia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología Dr. Mario Fatala Chaben; Argentina.
Fil: Bua, Jacqueline. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología Dr. Mario Fatala Chaben; Argentina.
Regulated cell death (RCD) involves a genetically encoded molecular machinery, which can be altered by means of pharmacologic and/or genetics interventions targeting the key components of such machinery. RCD often occurs in a delayed manner and is initiated in the context of adaptive responses that unsuccessfully attempt to restore cellular homeostasis. It is important to mention that the term RCD includes both physiological instances of death, referred to as ‘programmed cell death’, but also death processes that occur in pathological contexts. Our comprehension of cell death subroutines has progressed significantly, as the main molecular events underlying these mechanisms have been elucidated.
description Fil: Bustos, Patricia L. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología Dr. Mario Fatala Chaben; Argentina.
publishDate 2017
dc.date.none.fl_str_mv 2017
dc.type.none.fl_str_mv info:ar-repo/semantics/articulo
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv 2041-4889
http://sgc.anlis.gob.ar/handle/123456789/1442
10.1038/cddis.2017.431
identifier_str_mv 2041-4889
10.1038/cddis.2017.431
url http://sgc.anlis.gob.ar/handle/123456789/1442
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Cell death & disease
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Cell Death and Disease 2017;8:e3057
reponame:Sistema de Gestión del Conocimiento ANLIS MALBRÁN
instname:Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
instacron:ANLIS
reponame_str Sistema de Gestión del Conocimiento ANLIS MALBRÁN
collection Sistema de Gestión del Conocimiento ANLIS MALBRÁN
instname_str Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
instacron_str ANLIS
institution ANLIS
repository.name.fl_str_mv Sistema de Gestión del Conocimiento ANLIS MALBRÁN - Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
repository.mail.fl_str_mv biblioteca@anlis.gov.ar
_version_ 1844621855918391296
score 12.559606