Experimental and computational investigation of the substituent effects on the reduction of Fe³⁺ by 1,2-dihydroxybenzenes

• Autores: Salgado, Pablo Raúl; Contreras, David; Mansilla, Héctor D.; Márquez, Katherine; Vidal, Gladys; Cobos, Carlos Jorge; Mártire, Daniel Osvaldo
• Año de publicación: 2017
• Idioma: inglés
• Tipo de recurso: artículo
• Materia: Ciencias Exactas; Química; kinetics; 1,2-dihydroxybenzenes
• Institución: Universidad Nacional de La Plata

This study reports on the kinetics of the early steps that mediate the reactions of substituted 1,2-dihydroxybenzenes (1,2-DHB) with Fe³⁺. The rate constants of the three processes identified by means of the stopped-flow technique are affected by the electron-withdrawing or electron-donating abilities of the substituent. The fastest process is assigned to the formation of a 1 : 1 complex between Fe³⁺ and the 1,2-DHB, which is accompanied by proton loss. The second process involves the inner-sphere electron transfer from the ligand to Fe³⁺ and the slowest step is related to the deprotonation of one of the oxygen atoms bonded to the metal. A reaction mechanism is proposed on the basis of the experimental data and density functional theory (DFT) calculations on mono- and bidentate species with different degrees of protonation.
Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas