The Identification of New Histamine Derivatives in the Skin of Leptodactylus
- Autores
- Erspamer, V.; Vitali, T.; Roseghini, M.; Cei, José Miguel Alfredo María
- Año de publicación
- 1964
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Extracts of the skin of some South American amphibians belonging to the genus Leptodactylus contain, in addition to 5-hydroxyindolealkylamines and hydroxyphenylalkylamines, remarkable amounts of imidazolealkylamines. The species most rich in these compounds are Leptodactylus pentadactylus labyrinthicus and Leptodactylus laticeps. The skin of the former species contains not only histamine, N'-methyl- histamine and N', N'-dimethylhistamine but also two imidazo-c-pyridine derivatives hitherto unknown in nature: spinaceamine and 6-methylspinaceamine. The new findings permit a notable enlargement of our knowledge in the field of biogenic imidazolealkylamines and illustrate new possible metabolic pathways for histamine.
Material digitalizado en SEDICI gracias a la colaboración del Dr. Jorge Williams (FCNM-UNLP).
Facultad de Ciencias Naturales y Museo - Materia
-
Zoología
Skin
Amphibians
Leptodactylus - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- http://creativecommons.org/licenses/by-nc-sa/4.0/
- Repositorio
- Institución
- Universidad Nacional de La Plata
- OAI Identificador
- oai:sedici.unlp.edu.ar:10915/89940
Ver los metadatos del registro completo
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The Identification of New Histamine Derivatives in the Skin of LeptodactylusErspamer, V.Vitali, T.Roseghini, M.Cei, José Miguel Alfredo MaríaZoologíaSkinAmphibiansLeptodactylusExtracts of the skin of some South American amphibians belonging to the genus Leptodactylus contain, in addition to 5-hydroxyindolealkylamines and hydroxyphenylalkylamines, remarkable amounts of imidazolealkylamines. The species most rich in these compounds are Leptodactylus pentadactylus labyrinthicus and Leptodactylus laticeps. The skin of the former species contains not only histamine, N'-methyl- histamine and N', N'-dimethylhistamine but also two imidazo-c-pyridine derivatives hitherto unknown in nature: spinaceamine and 6-methylspinaceamine. The new findings permit a notable enlargement of our knowledge in the field of biogenic imidazolealkylamines and illustrate new possible metabolic pathways for histamine.Material digitalizado en SEDICI gracias a la colaboración del Dr. Jorge Williams (FCNM-UNLP).Facultad de Ciencias Naturales y Museo1964-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf620-629http://sedici.unlp.edu.ar/handle/10915/89940enginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-03T10:50:42Zoai:sedici.unlp.edu.ar:10915/89940Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-03 10:50:42.398SEDICI (UNLP) - Universidad Nacional de La Platafalse |
dc.title.none.fl_str_mv |
The Identification of New Histamine Derivatives in the Skin of Leptodactylus |
title |
The Identification of New Histamine Derivatives in the Skin of Leptodactylus |
spellingShingle |
The Identification of New Histamine Derivatives in the Skin of Leptodactylus Erspamer, V. Zoología Skin Amphibians Leptodactylus |
title_short |
The Identification of New Histamine Derivatives in the Skin of Leptodactylus |
title_full |
The Identification of New Histamine Derivatives in the Skin of Leptodactylus |
title_fullStr |
The Identification of New Histamine Derivatives in the Skin of Leptodactylus |
title_full_unstemmed |
The Identification of New Histamine Derivatives in the Skin of Leptodactylus |
title_sort |
The Identification of New Histamine Derivatives in the Skin of Leptodactylus |
dc.creator.none.fl_str_mv |
Erspamer, V. Vitali, T. Roseghini, M. Cei, José Miguel Alfredo María |
author |
Erspamer, V. |
author_facet |
Erspamer, V. Vitali, T. Roseghini, M. Cei, José Miguel Alfredo María |
author_role |
author |
author2 |
Vitali, T. Roseghini, M. Cei, José Miguel Alfredo María |
author2_role |
author author author |
dc.subject.none.fl_str_mv |
Zoología Skin Amphibians Leptodactylus |
topic |
Zoología Skin Amphibians Leptodactylus |
dc.description.none.fl_txt_mv |
Extracts of the skin of some South American amphibians belonging to the genus Leptodactylus contain, in addition to 5-hydroxyindolealkylamines and hydroxyphenylalkylamines, remarkable amounts of imidazolealkylamines. The species most rich in these compounds are Leptodactylus pentadactylus labyrinthicus and Leptodactylus laticeps. The skin of the former species contains not only histamine, N'-methyl- histamine and N', N'-dimethylhistamine but also two imidazo-c-pyridine derivatives hitherto unknown in nature: spinaceamine and 6-methylspinaceamine. The new findings permit a notable enlargement of our knowledge in the field of biogenic imidazolealkylamines and illustrate new possible metabolic pathways for histamine. Material digitalizado en SEDICI gracias a la colaboración del Dr. Jorge Williams (FCNM-UNLP). Facultad de Ciencias Naturales y Museo |
description |
Extracts of the skin of some South American amphibians belonging to the genus Leptodactylus contain, in addition to 5-hydroxyindolealkylamines and hydroxyphenylalkylamines, remarkable amounts of imidazolealkylamines. The species most rich in these compounds are Leptodactylus pentadactylus labyrinthicus and Leptodactylus laticeps. The skin of the former species contains not only histamine, N'-methyl- histamine and N', N'-dimethylhistamine but also two imidazo-c-pyridine derivatives hitherto unknown in nature: spinaceamine and 6-methylspinaceamine. The new findings permit a notable enlargement of our knowledge in the field of biogenic imidazolealkylamines and illustrate new possible metabolic pathways for histamine. |
publishDate |
1964 |
dc.date.none.fl_str_mv |
1964-06 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Articulo http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://sedici.unlp.edu.ar/handle/10915/89940 |
url |
http://sedici.unlp.edu.ar/handle/10915/89940 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) |
dc.format.none.fl_str_mv |
application/pdf 620-629 |
dc.source.none.fl_str_mv |
reponame:SEDICI (UNLP) instname:Universidad Nacional de La Plata instacron:UNLP |
reponame_str |
SEDICI (UNLP) |
collection |
SEDICI (UNLP) |
instname_str |
Universidad Nacional de La Plata |
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UNLP |
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SEDICI (UNLP) - Universidad Nacional de La Plata |
repository.mail.fl_str_mv |
alira@sedici.unlp.edu.ar |
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score |
13.13397 |