The Identification of New Histamine Derivatives in the Skin of Leptodactylus

Autores
Erspamer, V.; Vitali, T.; Roseghini, M.; Cei, José Miguel Alfredo María
Año de publicación
1964
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Extracts of the skin of some South American amphibians belonging to the genus Leptodactylus contain, in addition to 5-hydroxyindolealkylamines and hydroxyphenylalkylamines, remarkable amounts of imidazolealkylamines. The species most rich in these compounds are Leptodactylus pentadactylus labyrinthicus and Leptodactylus laticeps. The skin of the former species contains not only histamine, N'-methyl- histamine and N', N'-dimethylhistamine but also two imidazo-c-pyridine derivatives hitherto unknown in nature: spinaceamine and 6-methylspinaceamine. The new findings permit a notable enlargement of our knowledge in the field of biogenic imidazolealkylamines and illustrate new possible metabolic pathways for histamine.
Material digitalizado en SEDICI gracias a la colaboración del Dr. Jorge Williams (FCNM-UNLP).
Facultad de Ciencias Naturales y Museo
Materia
Zoología
Skin
Amphibians
Leptodactylus
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/89940

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oai_identifier_str oai:sedici.unlp.edu.ar:10915/89940
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network_name_str SEDICI (UNLP)
spelling The Identification of New Histamine Derivatives in the Skin of LeptodactylusErspamer, V.Vitali, T.Roseghini, M.Cei, José Miguel Alfredo MaríaZoologíaSkinAmphibiansLeptodactylusExtracts of the skin of some South American amphibians belonging to the genus Leptodactylus contain, in addition to 5-hydroxyindolealkylamines and hydroxyphenylalkylamines, remarkable amounts of imidazolealkylamines. The species most rich in these compounds are Leptodactylus pentadactylus labyrinthicus and Leptodactylus laticeps. The skin of the former species contains not only histamine, N'-methyl- histamine and N', N'-dimethylhistamine but also two imidazo-c-pyridine derivatives hitherto unknown in nature: spinaceamine and 6-methylspinaceamine. The new findings permit a notable enlargement of our knowledge in the field of biogenic imidazolealkylamines and illustrate new possible metabolic pathways for histamine.Material digitalizado en SEDICI gracias a la colaboración del Dr. Jorge Williams (FCNM-UNLP).Facultad de Ciencias Naturales y Museo1964-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf620-629http://sedici.unlp.edu.ar/handle/10915/89940enginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-03T10:50:42Zoai:sedici.unlp.edu.ar:10915/89940Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-03 10:50:42.398SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv The Identification of New Histamine Derivatives in the Skin of Leptodactylus
title The Identification of New Histamine Derivatives in the Skin of Leptodactylus
spellingShingle The Identification of New Histamine Derivatives in the Skin of Leptodactylus
Erspamer, V.
Zoología
Skin
Amphibians
Leptodactylus
title_short The Identification of New Histamine Derivatives in the Skin of Leptodactylus
title_full The Identification of New Histamine Derivatives in the Skin of Leptodactylus
title_fullStr The Identification of New Histamine Derivatives in the Skin of Leptodactylus
title_full_unstemmed The Identification of New Histamine Derivatives in the Skin of Leptodactylus
title_sort The Identification of New Histamine Derivatives in the Skin of Leptodactylus
dc.creator.none.fl_str_mv Erspamer, V.
Vitali, T.
Roseghini, M.
Cei, José Miguel Alfredo María
author Erspamer, V.
author_facet Erspamer, V.
Vitali, T.
Roseghini, M.
Cei, José Miguel Alfredo María
author_role author
author2 Vitali, T.
Roseghini, M.
Cei, José Miguel Alfredo María
author2_role author
author
author
dc.subject.none.fl_str_mv Zoología
Skin
Amphibians
Leptodactylus
topic Zoología
Skin
Amphibians
Leptodactylus
dc.description.none.fl_txt_mv Extracts of the skin of some South American amphibians belonging to the genus Leptodactylus contain, in addition to 5-hydroxyindolealkylamines and hydroxyphenylalkylamines, remarkable amounts of imidazolealkylamines. The species most rich in these compounds are Leptodactylus pentadactylus labyrinthicus and Leptodactylus laticeps. The skin of the former species contains not only histamine, N'-methyl- histamine and N', N'-dimethylhistamine but also two imidazo-c-pyridine derivatives hitherto unknown in nature: spinaceamine and 6-methylspinaceamine. The new findings permit a notable enlargement of our knowledge in the field of biogenic imidazolealkylamines and illustrate new possible metabolic pathways for histamine.
Material digitalizado en SEDICI gracias a la colaboración del Dr. Jorge Williams (FCNM-UNLP).
Facultad de Ciencias Naturales y Museo
description Extracts of the skin of some South American amphibians belonging to the genus Leptodactylus contain, in addition to 5-hydroxyindolealkylamines and hydroxyphenylalkylamines, remarkable amounts of imidazolealkylamines. The species most rich in these compounds are Leptodactylus pentadactylus labyrinthicus and Leptodactylus laticeps. The skin of the former species contains not only histamine, N'-methyl- histamine and N', N'-dimethylhistamine but also two imidazo-c-pyridine derivatives hitherto unknown in nature: spinaceamine and 6-methylspinaceamine. The new findings permit a notable enlargement of our knowledge in the field of biogenic imidazolealkylamines and illustrate new possible metabolic pathways for histamine.
publishDate 1964
dc.date.none.fl_str_mv 1964-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/89940
url http://sedici.unlp.edu.ar/handle/10915/89940
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
620-629
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instname_str Universidad Nacional de La Plata
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institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
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