Occurrence of candicine (p-HYDROXYPHENYLETHYLTRIMETHYLAMMONIUM) in extracts of the skin of <i>leptodactylus pentadactylus pentadactylus</i>

Autores
Erspamer, V.; Cei, José Miguel Alfredo María; Roseghini, M.
Año de publicación
1963
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
CANDICINE has been known for more than 30 years to be a natural constituent of some plants, more precisely of some Argentinian Cactaceae. The compound has now been found to occur in a vertebrate tissue also. The dry skin of five specimens of Leptodactylus pentadactylus pentadactylus, an Amazonium amphibian, was extracted twice with 70 per cent acetone. The combined extracts were concentrated under reduced pressure and the aqueous liquid shaken repeatedly with petroleum ether to remove fats. Then evaporation was continued and the syrupy residue taken up, by stirring, in 100 ml of 99 per cent ethanol. The liquid was then passed through a column of alkaline alumina. Elution was carried out with decreasing concentrations of ethanol, as described in detail in other papers. ’ The different eluates were suitably concentrated and then chromatographed on Whatman no. 1 paper.
Material digitalizado en SEDICI gracias a la colaboración del Dr. Jorge Williams (FCNM-UNLP).
Facultad de Ciencias Naturales y Museo
Materia
Zoología
Leptodactylus pentadactylus pentadactylus
Candicine
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/88411

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spelling Occurrence of candicine (p-HYDROXYPHENYLETHYLTRIMETHYLAMMONIUM) in extracts of the skin of <i>leptodactylus pentadactylus pentadactylus</i>Erspamer, V.Cei, José Miguel Alfredo MaríaRoseghini, M.ZoologíaLeptodactylus pentadactylus pentadactylusCandicineCANDICINE has been known for more than 30 years to be a natural constituent of some plants, more precisely of some Argentinian Cactaceae. The compound has now been found to occur in a vertebrate tissue also. The dry skin of five specimens of <i>Leptodactylus pentadactylus pentadactylus</i>, an Amazonium amphibian, was extracted twice with 70 per cent acetone. The combined extracts were concentrated under reduced pressure and the aqueous liquid shaken repeatedly with petroleum ether to remove fats. Then evaporation was continued and the syrupy residue taken up, by stirring, in 100 ml of 99 per cent ethanol. The liquid was then passed through a column of alkaline alumina. Elution was carried out with decreasing concentrations of ethanol, as described in detail in other papers. ’ The different eluates were suitably concentrated and then chromatographed on Whatman no. 1 paper.Material digitalizado en SEDICI gracias a la colaboración del Dr. Jorge Williams (FCNM-UNLP).Facultad de Ciencias Naturales y Museo1963info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf825-827http://sedici.unlp.edu.ar/handle/10915/88411enginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-10-15T11:09:37Zoai:sedici.unlp.edu.ar:10915/88411Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-10-15 11:09:37.659SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Occurrence of candicine (p-HYDROXYPHENYLETHYLTRIMETHYLAMMONIUM) in extracts of the skin of <i>leptodactylus pentadactylus pentadactylus</i>
title Occurrence of candicine (p-HYDROXYPHENYLETHYLTRIMETHYLAMMONIUM) in extracts of the skin of <i>leptodactylus pentadactylus pentadactylus</i>
spellingShingle Occurrence of candicine (p-HYDROXYPHENYLETHYLTRIMETHYLAMMONIUM) in extracts of the skin of <i>leptodactylus pentadactylus pentadactylus</i>
Erspamer, V.
Zoología
Leptodactylus pentadactylus pentadactylus
Candicine
title_short Occurrence of candicine (p-HYDROXYPHENYLETHYLTRIMETHYLAMMONIUM) in extracts of the skin of <i>leptodactylus pentadactylus pentadactylus</i>
title_full Occurrence of candicine (p-HYDROXYPHENYLETHYLTRIMETHYLAMMONIUM) in extracts of the skin of <i>leptodactylus pentadactylus pentadactylus</i>
title_fullStr Occurrence of candicine (p-HYDROXYPHENYLETHYLTRIMETHYLAMMONIUM) in extracts of the skin of <i>leptodactylus pentadactylus pentadactylus</i>
title_full_unstemmed Occurrence of candicine (p-HYDROXYPHENYLETHYLTRIMETHYLAMMONIUM) in extracts of the skin of <i>leptodactylus pentadactylus pentadactylus</i>
title_sort Occurrence of candicine (p-HYDROXYPHENYLETHYLTRIMETHYLAMMONIUM) in extracts of the skin of <i>leptodactylus pentadactylus pentadactylus</i>
dc.creator.none.fl_str_mv Erspamer, V.
Cei, José Miguel Alfredo María
Roseghini, M.
author Erspamer, V.
author_facet Erspamer, V.
Cei, José Miguel Alfredo María
Roseghini, M.
author_role author
author2 Cei, José Miguel Alfredo María
Roseghini, M.
author2_role author
author
dc.subject.none.fl_str_mv Zoología
Leptodactylus pentadactylus pentadactylus
Candicine
topic Zoología
Leptodactylus pentadactylus pentadactylus
Candicine
dc.description.none.fl_txt_mv CANDICINE has been known for more than 30 years to be a natural constituent of some plants, more precisely of some Argentinian Cactaceae. The compound has now been found to occur in a vertebrate tissue also. The dry skin of five specimens of <i>Leptodactylus pentadactylus pentadactylus</i>, an Amazonium amphibian, was extracted twice with 70 per cent acetone. The combined extracts were concentrated under reduced pressure and the aqueous liquid shaken repeatedly with petroleum ether to remove fats. Then evaporation was continued and the syrupy residue taken up, by stirring, in 100 ml of 99 per cent ethanol. The liquid was then passed through a column of alkaline alumina. Elution was carried out with decreasing concentrations of ethanol, as described in detail in other papers. ’ The different eluates were suitably concentrated and then chromatographed on Whatman no. 1 paper.
Material digitalizado en SEDICI gracias a la colaboración del Dr. Jorge Williams (FCNM-UNLP).
Facultad de Ciencias Naturales y Museo
description CANDICINE has been known for more than 30 years to be a natural constituent of some plants, more precisely of some Argentinian Cactaceae. The compound has now been found to occur in a vertebrate tissue also. The dry skin of five specimens of <i>Leptodactylus pentadactylus pentadactylus</i>, an Amazonium amphibian, was extracted twice with 70 per cent acetone. The combined extracts were concentrated under reduced pressure and the aqueous liquid shaken repeatedly with petroleum ether to remove fats. Then evaporation was continued and the syrupy residue taken up, by stirring, in 100 ml of 99 per cent ethanol. The liquid was then passed through a column of alkaline alumina. Elution was carried out with decreasing concentrations of ethanol, as described in detail in other papers. ’ The different eluates were suitably concentrated and then chromatographed on Whatman no. 1 paper.
publishDate 1963
dc.date.none.fl_str_mv 1963
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
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url http://sedici.unlp.edu.ar/handle/10915/88411
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
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