Enteroinsular axis: physiology and pathophysiology : Metabolic and pleiotropic effects of incretins

Autores
Gonzalez, Claudio; Gagliardino, Juan José
Año de publicación
2009
Idioma
inglés
Tipo de recurso
reseña artículo
Estado
versión publicada
Descripción
A better understanding of GLP-1 and GIP biology, physiology and pathophysiology are currently within the focus of many labs across the world, since they are in the basement of the development of new therapies for treating type 2 Diabetes and obesity. Many of the main aspects of the incretins physiology are naturally complex, because a myriad of pleitropic actions, involving several biological systems, displaying marked interspecies and inter-individual variability. The search for new regulatory mechanisms involving the entero-insular axis is also extremely active, and novel promising compounds are currently being studied. Even when it results impossible to predict the long term success of the pharmacological intervention on these new targets, further advances in this area are granted.
Sociedad Argentina de Fisiología
Materia
Ciencias Médicas
incretins
diabetes
obesity
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/129074
Acceder
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network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Enteroinsular axis: physiology and pathophysiology : Metabolic and pleiotropic effects of incretinsGonzalez, ClaudioGagliardino, Juan JoséCiencias MédicasincretinsdiabetesobesityA better understanding of GLP-1 and GIP biology, physiology and pathophysiology are currently within the focus of many labs across the world, since they are in the basement of the development of new therapies for treating type 2 Diabetes and obesity. Many of the main aspects of the incretins physiology are naturally complex, because a myriad of pleitropic actions, involving several biological systems, displaying marked interspecies and inter-individual variability. The search for new regulatory mechanisms involving the entero-insular axis is also extremely active, and novel promising compounds are currently being studied. Even when it results impossible to predict the long term success of the pharmacological intervention on these new targets, further advances in this area are granted.Sociedad Argentina de Fisiología2009info:eu-repo/semantics/reviewinfo:eu-repo/semantics/publishedVersionRevisionhttp://purl.org/coar/resource_type/c_dcae04bcinfo:ar-repo/semantics/resenaArticuloapplication/pdf37-47http://sedici.unlp.edu.ar/handle/10915/129074enginfo:eu-repo/semantics/altIdentifier/url/https://pmr.safisiol.org.ar/archive/id/26info:eu-repo/semantics/altIdentifier/issn/1669-5402info:eu-repo/semantics/altIdentifier/issn/1669-5410info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-10-15T11:23:19Zoai:sedici.unlp.edu.ar:10915/129074Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-10-15 11:23:19.486SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Enteroinsular axis: physiology and pathophysiology : Metabolic and pleiotropic effects of incretins
title Enteroinsular axis: physiology and pathophysiology : Metabolic and pleiotropic effects of incretins
spellingShingle Enteroinsular axis: physiology and pathophysiology : Metabolic and pleiotropic effects of incretins
Gonzalez, Claudio
Ciencias Médicas
incretins
diabetes
obesity
title_short Enteroinsular axis: physiology and pathophysiology : Metabolic and pleiotropic effects of incretins
title_full Enteroinsular axis: physiology and pathophysiology : Metabolic and pleiotropic effects of incretins
title_fullStr Enteroinsular axis: physiology and pathophysiology : Metabolic and pleiotropic effects of incretins
title_full_unstemmed Enteroinsular axis: physiology and pathophysiology : Metabolic and pleiotropic effects of incretins
title_sort Enteroinsular axis: physiology and pathophysiology : Metabolic and pleiotropic effects of incretins
dc.creator.none.fl_str_mv Gonzalez, Claudio
Gagliardino, Juan José
author Gonzalez, Claudio
author_facet Gonzalez, Claudio
Gagliardino, Juan José
author_role author
author2 Gagliardino, Juan José
author2_role author
dc.subject.none.fl_str_mv Ciencias Médicas
incretins
diabetes
obesity
topic Ciencias Médicas
incretins
diabetes
obesity
dc.description.none.fl_txt_mv A better understanding of GLP-1 and GIP biology, physiology and pathophysiology are currently within the focus of many labs across the world, since they are in the basement of the development of new therapies for treating type 2 Diabetes and obesity. Many of the main aspects of the incretins physiology are naturally complex, because a myriad of pleitropic actions, involving several biological systems, displaying marked interspecies and inter-individual variability. The search for new regulatory mechanisms involving the entero-insular axis is also extremely active, and novel promising compounds are currently being studied. Even when it results impossible to predict the long term success of the pharmacological intervention on these new targets, further advances in this area are granted.
Sociedad Argentina de Fisiología
description A better understanding of GLP-1 and GIP biology, physiology and pathophysiology are currently within the focus of many labs across the world, since they are in the basement of the development of new therapies for treating type 2 Diabetes and obesity. Many of the main aspects of the incretins physiology are naturally complex, because a myriad of pleitropic actions, involving several biological systems, displaying marked interspecies and inter-individual variability. The search for new regulatory mechanisms involving the entero-insular axis is also extremely active, and novel promising compounds are currently being studied. Even when it results impossible to predict the long term success of the pharmacological intervention on these new targets, further advances in this area are granted.
publishDate 2009
dc.date.none.fl_str_mv 2009
dc.type.none.fl_str_mv info:eu-repo/semantics/review
info:eu-repo/semantics/publishedVersion
Revision
http://purl.org/coar/resource_type/c_dcae04bc
info:ar-repo/semantics/resenaArticulo
format review
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/129074
url http://sedici.unlp.edu.ar/handle/10915/129074
dc.language.none.fl_str_mv eng
language eng
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info:eu-repo/semantics/altIdentifier/issn/1669-5402
info:eu-repo/semantics/altIdentifier/issn/1669-5410
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.format.none.fl_str_mv application/pdf
37-47
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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