Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion

Autores
Zubiría, María Guillermina; Alzamendi, Ana; Ongaro Gambino, Luisina; Spinedi, Eduardo Julio; Giovambattista, Andrés; Gordeladze, Jan
Año de publicación
2017
Idioma
inglés
Tipo de recurso
parte de libro
Estado
versión publicada
Descripción
White adipose tissue (WAT) expansion is related to the development of metabolic disorders found in obesity. WAT expansion is the result of generation of new adipose cells by activation of adipogenesis and/or the increase in adipose cell size (hypertrophy). The balance between these two processes determines whether WAT expansion occurs predominantly by hyperplasia, which means the increase in the number of adipocytes, or hypertrophy. Hypertrophic adipocytes are characterized by changes in adipokine secretion pattern, insulin resistance and altered lipid metabolism, which is the reason why WAT-hypertrophic expansion is considered unhealthy. Conversely, the generation of new mature adipocytes by adipogenesis contributes to reduction of the development of hypertrophic adipocytes and therefore maintain normal WAT functions, leading to healthy hyperplastic expansion. The adipogenic capacity of adipose tissue depends on the adipogenic potential and the number of adipocyte precursor cells. Different factors are known to regulate adipogenic process and adipose tissue function, contributing to a healthy or unhealthy expansion that occurs under positive energy balance. This chapter discusses the role of fructose intake and glucocorticoids and testosterone as regulators of adipose tissue function and expansion.
Facultad de Ciencias Médicas
Materia
Ciencias Exactas
Ciencias Médicas
Adiposidad
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/3.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/74721
Acceder
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oai_identifier_str oai:sedici.unlp.edu.ar:10915/74721
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue ExpansionZubiría, María GuillerminaAlzamendi, AnaOngaro Gambino, LuisinaSpinedi, Eduardo JulioGiovambattista, AndrésGordeladze, JanCiencias ExactasCiencias MédicasAdiposidadWhite adipose tissue (WAT) expansion is related to the development of metabolic disorders found in obesity. WAT expansion is the result of generation of new adipose cells by activation of adipogenesis and/or the increase in adipose cell size (hypertrophy). The balance between these two processes determines whether WAT expansion occurs predominantly by hyperplasia, which means the increase in the number of adipocytes, or hypertrophy. Hypertrophic adipocytes are characterized by changes in adipokine secretion pattern, insulin resistance and altered lipid metabolism, which is the reason why WAT-hypertrophic expansion is considered unhealthy. Conversely, the generation of new mature adipocytes by adipogenesis contributes to reduction of the development of hypertrophic adipocytes and therefore maintain normal WAT functions, leading to healthy hyperplastic expansion. The adipogenic capacity of adipose tissue depends on the adipogenic potential and the number of adipocyte precursor cells. Different factors are known to regulate adipogenic process and adipose tissue function, contributing to a healthy or unhealthy expansion that occurs under positive energy balance. This chapter discusses the role of fructose intake and glucocorticoids and testosterone as regulators of adipose tissue function and expansion.Facultad de Ciencias MédicasIntech2017-03-15info:eu-repo/semantics/bookPartinfo:eu-repo/semantics/publishedVersionCapitulo de librohttp://purl.org/coar/resource_type/c_3248info:ar-repo/semantics/parteDeLibroapplication/pdf165-187http://sedici.unlp.edu.ar/handle/10915/74721enginfo:eu-repo/semantics/altIdentifier/isbn/978-953-51-2996-7info:eu-repo/semantics/altIdentifier/doi/10.5772/65927info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/3.0/Creative Commons Attribution 3.0 Unported (CC BY 3.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-10-22T16:53:45Zoai:sedici.unlp.edu.ar:10915/74721Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-10-22 16:53:45.26SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion
title Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion
spellingShingle Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion
Zubiría, María Guillermina
Ciencias Exactas
Ciencias Médicas
Adiposidad
title_short Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion
title_full Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion
title_fullStr Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion
title_full_unstemmed Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion
title_sort Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion
dc.creator.none.fl_str_mv Zubiría, María Guillermina
Alzamendi, Ana
Ongaro Gambino, Luisina
Spinedi, Eduardo Julio
Giovambattista, Andrés
Gordeladze, Jan
author Zubiría, María Guillermina
author_facet Zubiría, María Guillermina
Alzamendi, Ana
Ongaro Gambino, Luisina
Spinedi, Eduardo Julio
Giovambattista, Andrés
Gordeladze, Jan
author_role author
author2 Alzamendi, Ana
Ongaro Gambino, Luisina
Spinedi, Eduardo Julio
Giovambattista, Andrés
Gordeladze, Jan
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Ciencias Exactas
Ciencias Médicas
Adiposidad
topic Ciencias Exactas
Ciencias Médicas
Adiposidad
dc.description.none.fl_txt_mv White adipose tissue (WAT) expansion is related to the development of metabolic disorders found in obesity. WAT expansion is the result of generation of new adipose cells by activation of adipogenesis and/or the increase in adipose cell size (hypertrophy). The balance between these two processes determines whether WAT expansion occurs predominantly by hyperplasia, which means the increase in the number of adipocytes, or hypertrophy. Hypertrophic adipocytes are characterized by changes in adipokine secretion pattern, insulin resistance and altered lipid metabolism, which is the reason why WAT-hypertrophic expansion is considered unhealthy. Conversely, the generation of new mature adipocytes by adipogenesis contributes to reduction of the development of hypertrophic adipocytes and therefore maintain normal WAT functions, leading to healthy hyperplastic expansion. The adipogenic capacity of adipose tissue depends on the adipogenic potential and the number of adipocyte precursor cells. Different factors are known to regulate adipogenic process and adipose tissue function, contributing to a healthy or unhealthy expansion that occurs under positive energy balance. This chapter discusses the role of fructose intake and glucocorticoids and testosterone as regulators of adipose tissue function and expansion.
Facultad de Ciencias Médicas
description White adipose tissue (WAT) expansion is related to the development of metabolic disorders found in obesity. WAT expansion is the result of generation of new adipose cells by activation of adipogenesis and/or the increase in adipose cell size (hypertrophy). The balance between these two processes determines whether WAT expansion occurs predominantly by hyperplasia, which means the increase in the number of adipocytes, or hypertrophy. Hypertrophic adipocytes are characterized by changes in adipokine secretion pattern, insulin resistance and altered lipid metabolism, which is the reason why WAT-hypertrophic expansion is considered unhealthy. Conversely, the generation of new mature adipocytes by adipogenesis contributes to reduction of the development of hypertrophic adipocytes and therefore maintain normal WAT functions, leading to healthy hyperplastic expansion. The adipogenic capacity of adipose tissue depends on the adipogenic potential and the number of adipocyte precursor cells. Different factors are known to regulate adipogenic process and adipose tissue function, contributing to a healthy or unhealthy expansion that occurs under positive energy balance. This chapter discusses the role of fructose intake and glucocorticoids and testosterone as regulators of adipose tissue function and expansion.
publishDate 2017
dc.date.none.fl_str_mv 2017-03-15
dc.type.none.fl_str_mv info:eu-repo/semantics/bookPart
info:eu-repo/semantics/publishedVersion
Capitulo de libro
http://purl.org/coar/resource_type/c_3248
info:ar-repo/semantics/parteDeLibro
format bookPart
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/74721
url http://sedici.unlp.edu.ar/handle/10915/74721
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/isbn/978-953-51-2996-7
info:eu-repo/semantics/altIdentifier/doi/10.5772/65927
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/3.0/
Creative Commons Attribution 3.0 Unported (CC BY 3.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/3.0/
Creative Commons Attribution 3.0 Unported (CC BY 3.0)
dc.format.none.fl_str_mv application/pdf
165-187
dc.publisher.none.fl_str_mv Intech
publisher.none.fl_str_mv Intech
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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score 12.982451

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