Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion
- Autores
- Zubiría, María Guillermina; Alzamendi, Ana; Ongaro Gambino, Luisina; Spinedi, Eduardo Julio; Giovambattista, Andrés; Gordeladze, Jan
- Año de publicación
- 2017
- Idioma
- inglés
- Tipo de recurso
- parte de libro
- Estado
- versión publicada
- Descripción
- White adipose tissue (WAT) expansion is related to the development of metabolic disorders found in obesity. WAT expansion is the result of generation of new adipose cells by activation of adipogenesis and/or the increase in adipose cell size (hypertrophy). The balance between these two processes determines whether WAT expansion occurs predominantly by hyperplasia, which means the increase in the number of adipocytes, or hypertrophy. Hypertrophic adipocytes are characterized by changes in adipokine secretion pattern, insulin resistance and altered lipid metabolism, which is the reason why WAT-hypertrophic expansion is considered unhealthy. Conversely, the generation of new mature adipocytes by adipogenesis contributes to reduction of the development of hypertrophic adipocytes and therefore maintain normal WAT functions, leading to healthy hyperplastic expansion. The adipogenic capacity of adipose tissue depends on the adipogenic potential and the number of adipocyte precursor cells. Different factors are known to regulate adipogenic process and adipose tissue function, contributing to a healthy or unhealthy expansion that occurs under positive energy balance. This chapter discusses the role of fructose intake and glucocorticoids and testosterone as regulators of adipose tissue function and expansion.
Facultad de Ciencias Médicas - Materia
-
Ciencias Exactas
Ciencias Médicas
Adiposidad - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- http://creativecommons.org/licenses/by/3.0/
- Repositorio
- Institución
- Universidad Nacional de La Plata
- OAI Identificador
- oai:sedici.unlp.edu.ar:10915/74721
Ver los metadatos del registro completo
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Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue ExpansionZubiría, María GuillerminaAlzamendi, AnaOngaro Gambino, LuisinaSpinedi, Eduardo JulioGiovambattista, AndrésGordeladze, JanCiencias ExactasCiencias MédicasAdiposidadWhite adipose tissue (WAT) expansion is related to the development of metabolic disorders found in obesity. WAT expansion is the result of generation of new adipose cells by activation of adipogenesis and/or the increase in adipose cell size (hypertrophy). The balance between these two processes determines whether WAT expansion occurs predominantly by hyperplasia, which means the increase in the number of adipocytes, or hypertrophy. Hypertrophic adipocytes are characterized by changes in adipokine secretion pattern, insulin resistance and altered lipid metabolism, which is the reason why WAT-hypertrophic expansion is considered unhealthy. Conversely, the generation of new mature adipocytes by adipogenesis contributes to reduction of the development of hypertrophic adipocytes and therefore maintain normal WAT functions, leading to healthy hyperplastic expansion. The adipogenic capacity of adipose tissue depends on the adipogenic potential and the number of adipocyte precursor cells. Different factors are known to regulate adipogenic process and adipose tissue function, contributing to a healthy or unhealthy expansion that occurs under positive energy balance. This chapter discusses the role of fructose intake and glucocorticoids and testosterone as regulators of adipose tissue function and expansion.Facultad de Ciencias MédicasIntech2017-03-15info:eu-repo/semantics/bookPartinfo:eu-repo/semantics/publishedVersionCapitulo de librohttp://purl.org/coar/resource_type/c_3248info:ar-repo/semantics/parteDeLibroapplication/pdf165-187http://sedici.unlp.edu.ar/handle/10915/74721enginfo:eu-repo/semantics/altIdentifier/isbn/978-953-51-2996-7info:eu-repo/semantics/altIdentifier/doi/10.5772/65927info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/3.0/Creative Commons Attribution 3.0 Unported (CC BY 3.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:12:51Zoai:sedici.unlp.edu.ar:10915/74721Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:12:52.146SEDICI (UNLP) - Universidad Nacional de La Platafalse |
dc.title.none.fl_str_mv |
Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion |
title |
Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion |
spellingShingle |
Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion Zubiría, María Guillermina Ciencias Exactas Ciencias Médicas Adiposidad |
title_short |
Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion |
title_full |
Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion |
title_fullStr |
Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion |
title_full_unstemmed |
Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion |
title_sort |
Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion |
dc.creator.none.fl_str_mv |
Zubiría, María Guillermina Alzamendi, Ana Ongaro Gambino, Luisina Spinedi, Eduardo Julio Giovambattista, Andrés Gordeladze, Jan |
author |
Zubiría, María Guillermina |
author_facet |
Zubiría, María Guillermina Alzamendi, Ana Ongaro Gambino, Luisina Spinedi, Eduardo Julio Giovambattista, Andrés Gordeladze, Jan |
author_role |
author |
author2 |
Alzamendi, Ana Ongaro Gambino, Luisina Spinedi, Eduardo Julio Giovambattista, Andrés Gordeladze, Jan |
author2_role |
author author author author author |
dc.subject.none.fl_str_mv |
Ciencias Exactas Ciencias Médicas Adiposidad |
topic |
Ciencias Exactas Ciencias Médicas Adiposidad |
dc.description.none.fl_txt_mv |
White adipose tissue (WAT) expansion is related to the development of metabolic disorders found in obesity. WAT expansion is the result of generation of new adipose cells by activation of adipogenesis and/or the increase in adipose cell size (hypertrophy). The balance between these two processes determines whether WAT expansion occurs predominantly by hyperplasia, which means the increase in the number of adipocytes, or hypertrophy. Hypertrophic adipocytes are characterized by changes in adipokine secretion pattern, insulin resistance and altered lipid metabolism, which is the reason why WAT-hypertrophic expansion is considered unhealthy. Conversely, the generation of new mature adipocytes by adipogenesis contributes to reduction of the development of hypertrophic adipocytes and therefore maintain normal WAT functions, leading to healthy hyperplastic expansion. The adipogenic capacity of adipose tissue depends on the adipogenic potential and the number of adipocyte precursor cells. Different factors are known to regulate adipogenic process and adipose tissue function, contributing to a healthy or unhealthy expansion that occurs under positive energy balance. This chapter discusses the role of fructose intake and glucocorticoids and testosterone as regulators of adipose tissue function and expansion. Facultad de Ciencias Médicas |
description |
White adipose tissue (WAT) expansion is related to the development of metabolic disorders found in obesity. WAT expansion is the result of generation of new adipose cells by activation of adipogenesis and/or the increase in adipose cell size (hypertrophy). The balance between these two processes determines whether WAT expansion occurs predominantly by hyperplasia, which means the increase in the number of adipocytes, or hypertrophy. Hypertrophic adipocytes are characterized by changes in adipokine secretion pattern, insulin resistance and altered lipid metabolism, which is the reason why WAT-hypertrophic expansion is considered unhealthy. Conversely, the generation of new mature adipocytes by adipogenesis contributes to reduction of the development of hypertrophic adipocytes and therefore maintain normal WAT functions, leading to healthy hyperplastic expansion. The adipogenic capacity of adipose tissue depends on the adipogenic potential and the number of adipocyte precursor cells. Different factors are known to regulate adipogenic process and adipose tissue function, contributing to a healthy or unhealthy expansion that occurs under positive energy balance. This chapter discusses the role of fructose intake and glucocorticoids and testosterone as regulators of adipose tissue function and expansion. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-03-15 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/bookPart info:eu-repo/semantics/publishedVersion Capitulo de libro http://purl.org/coar/resource_type/c_3248 info:ar-repo/semantics/parteDeLibro |
format |
bookPart |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://sedici.unlp.edu.ar/handle/10915/74721 |
url |
http://sedici.unlp.edu.ar/handle/10915/74721 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
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info:eu-repo/semantics/altIdentifier/isbn/978-953-51-2996-7 info:eu-repo/semantics/altIdentifier/doi/10.5772/65927 |
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info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/3.0/ Creative Commons Attribution 3.0 Unported (CC BY 3.0) |
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openAccess |
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http://creativecommons.org/licenses/by/3.0/ Creative Commons Attribution 3.0 Unported (CC BY 3.0) |
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application/pdf 165-187 |
dc.publisher.none.fl_str_mv |
Intech |
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SEDICI (UNLP) - Universidad Nacional de La Plata |
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