Cell volume regulation and aquaporins

Autores
Capurro, Claudia; Galizia, Luciano; Ford, Paula
Año de publicación
2008
Idioma
inglés
Tipo de recurso
reseña artículo
Estado
versión publicada
Descripción
In the recent years, the importance of the volume of a given cell has been accepted not only in defining its intracellular osmolality and its shape, but also in defining other cellular functions, such as transepithelial transport, cell migration, cell growth, cell death and the regulation of intracellular metabolism (35). Since most cells have to perform these physiological functions under a variable osmotic stress, cell volume must be carefully regulated. Based on the origin of the disturbance, cell volume changes are frequently classified into two categories: anisosmotic (alterations in extracellular solute concentration) and isosmotic (alterations in intracellular solute concentration) volume changes. Because of the relatively high permeability of the plasma membrane for water, any such gradient results in the immediate flow of water into or out of the cell causing cell swelling or shrinkage. To regulate cell volume, cells use channels and transport systems to flux osmolytes across the plasma membrane, followed by the obligatory movement of water. The current review reflects these developments and focuses on the contributions of aquaporins water channels in regulatory volume processes in a variety of cells.
Sociedad Argentina de Fisiología
Materia
Ciencias Médicas
cells
cell volume
aquaporins
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/129070

id SEDICI_a08f47aeeb84dc8edb061afc09c499a2
oai_identifier_str oai:sedici.unlp.edu.ar:10915/129070
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Cell volume regulation and aquaporinsCapurro, ClaudiaGalizia, LucianoFord, PaulaCiencias Médicascellscell volumeaquaporinsIn the recent years, the importance of the volume of a given cell has been accepted not only in defining its intracellular osmolality and its shape, but also in defining other cellular functions, such as transepithelial transport, cell migration, cell growth, cell death and the regulation of intracellular metabolism (35). Since most cells have to perform these physiological functions under a variable osmotic stress, cell volume must be carefully regulated. Based on the origin of the disturbance, cell volume changes are frequently classified into two categories: anisosmotic (alterations in extracellular solute concentration) and isosmotic (alterations in intracellular solute concentration) volume changes. Because of the relatively high permeability of the plasma membrane for water, any such gradient results in the immediate flow of water into or out of the cell causing cell swelling or shrinkage. To regulate cell volume, cells use channels and transport systems to flux osmolytes across the plasma membrane, followed by the obligatory movement of water. The current review reflects these developments and focuses on the contributions of aquaporins water channels in regulatory volume processes in a variety of cells.Sociedad Argentina de Fisiología2008info:eu-repo/semantics/reviewinfo:eu-repo/semantics/publishedVersionRevisionhttp://purl.org/coar/resource_type/c_dcae04bcinfo:ar-repo/semantics/resenaArticuloapplication/pdf9-17http://sedici.unlp.edu.ar/handle/10915/129070enginfo:eu-repo/semantics/altIdentifier/url/https://pmr.safisiol.org.ar/archive/id/20info:eu-repo/semantics/altIdentifier/issn/1669-5402info:eu-repo/semantics/altIdentifier/issn/1669-5410info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:31:27Zoai:sedici.unlp.edu.ar:10915/129070Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:31:27.722SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Cell volume regulation and aquaporins
title Cell volume regulation and aquaporins
spellingShingle Cell volume regulation and aquaporins
Capurro, Claudia
Ciencias Médicas
cells
cell volume
aquaporins
title_short Cell volume regulation and aquaporins
title_full Cell volume regulation and aquaporins
title_fullStr Cell volume regulation and aquaporins
title_full_unstemmed Cell volume regulation and aquaporins
title_sort Cell volume regulation and aquaporins
dc.creator.none.fl_str_mv Capurro, Claudia
Galizia, Luciano
Ford, Paula
author Capurro, Claudia
author_facet Capurro, Claudia
Galizia, Luciano
Ford, Paula
author_role author
author2 Galizia, Luciano
Ford, Paula
author2_role author
author
dc.subject.none.fl_str_mv Ciencias Médicas
cells
cell volume
aquaporins
topic Ciencias Médicas
cells
cell volume
aquaporins
dc.description.none.fl_txt_mv In the recent years, the importance of the volume of a given cell has been accepted not only in defining its intracellular osmolality and its shape, but also in defining other cellular functions, such as transepithelial transport, cell migration, cell growth, cell death and the regulation of intracellular metabolism (35). Since most cells have to perform these physiological functions under a variable osmotic stress, cell volume must be carefully regulated. Based on the origin of the disturbance, cell volume changes are frequently classified into two categories: anisosmotic (alterations in extracellular solute concentration) and isosmotic (alterations in intracellular solute concentration) volume changes. Because of the relatively high permeability of the plasma membrane for water, any such gradient results in the immediate flow of water into or out of the cell causing cell swelling or shrinkage. To regulate cell volume, cells use channels and transport systems to flux osmolytes across the plasma membrane, followed by the obligatory movement of water. The current review reflects these developments and focuses on the contributions of aquaporins water channels in regulatory volume processes in a variety of cells.
Sociedad Argentina de Fisiología
description In the recent years, the importance of the volume of a given cell has been accepted not only in defining its intracellular osmolality and its shape, but also in defining other cellular functions, such as transepithelial transport, cell migration, cell growth, cell death and the regulation of intracellular metabolism (35). Since most cells have to perform these physiological functions under a variable osmotic stress, cell volume must be carefully regulated. Based on the origin of the disturbance, cell volume changes are frequently classified into two categories: anisosmotic (alterations in extracellular solute concentration) and isosmotic (alterations in intracellular solute concentration) volume changes. Because of the relatively high permeability of the plasma membrane for water, any such gradient results in the immediate flow of water into or out of the cell causing cell swelling or shrinkage. To regulate cell volume, cells use channels and transport systems to flux osmolytes across the plasma membrane, followed by the obligatory movement of water. The current review reflects these developments and focuses on the contributions of aquaporins water channels in regulatory volume processes in a variety of cells.
publishDate 2008
dc.date.none.fl_str_mv 2008
dc.type.none.fl_str_mv info:eu-repo/semantics/review
info:eu-repo/semantics/publishedVersion
Revision
http://purl.org/coar/resource_type/c_dcae04bc
info:ar-repo/semantics/resenaArticulo
format review
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/129070
url http://sedici.unlp.edu.ar/handle/10915/129070
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://pmr.safisiol.org.ar/archive/id/20
info:eu-repo/semantics/altIdentifier/issn/1669-5402
info:eu-repo/semantics/altIdentifier/issn/1669-5410
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.format.none.fl_str_mv application/pdf
9-17
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
_version_ 1844616194302148608
score 13.070432