Cell Volume Regulation and Aquaporins
- Autores
- Capurro, Claudia Graciela; Galicia, Luciano; Ford, Paula
- Año de publicación
- 2009
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- In the recent years, the importance of the volume of a given cell has been accepted not only in defining its intracellular osmolality and its shape, but also in defining other cellular functions, such as transepithelial transport, cell migration, cell growth, cell death and the regulation of intracellular metabolism (35). Since most cells have to perform these physiological functions under a variable osmotic stress, cell volume must be carefully regulated. Based on the origin of the disturbance, cell volume changes are frequently classified into two categories: anisosmotic (alterations in extracellular solute concentration) and isosmotic (alterations in intracellular solute concentration) volume changes. Because of the relatively high permeability of the plasma membrane for water, any such gradient results in the immediate flow of water into or out of the cell causing cell swelling or shrinkage. To regulate cell volume, cells use channels and transport systems to flux osmolytes across the plasma membrane, followed by the obligatory movement of water. The current review reflects these developments and focuses on the contributions of aquaporins water channels in regulatory volume processes in a variety of cells.
Fil: Capurro, Claudia Graciela. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas. Laboratorio de Biomembranas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Fil: Galicia, Luciano. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas. Laboratorio de Biomembranas; Argentina
Fil: Ford, Paula. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas. Laboratorio de Biomembranas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina - Materia
-
CELL VOLUME REGULATION
AQUAPORINS
RVD
RVI - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/117816
Ver los metadatos del registro completo
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Cell Volume Regulation and AquaporinsCapurro, Claudia GracielaGalicia, LucianoFord, PaulaCELL VOLUME REGULATIONAQUAPORINSRVDRVIhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3In the recent years, the importance of the volume of a given cell has been accepted not only in defining its intracellular osmolality and its shape, but also in defining other cellular functions, such as transepithelial transport, cell migration, cell growth, cell death and the regulation of intracellular metabolism (35). Since most cells have to perform these physiological functions under a variable osmotic stress, cell volume must be carefully regulated. Based on the origin of the disturbance, cell volume changes are frequently classified into two categories: anisosmotic (alterations in extracellular solute concentration) and isosmotic (alterations in intracellular solute concentration) volume changes. Because of the relatively high permeability of the plasma membrane for water, any such gradient results in the immediate flow of water into or out of the cell causing cell swelling or shrinkage. To regulate cell volume, cells use channels and transport systems to flux osmolytes across the plasma membrane, followed by the obligatory movement of water. The current review reflects these developments and focuses on the contributions of aquaporins water channels in regulatory volume processes in a variety of cells.Fil: Capurro, Claudia Graciela. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas. Laboratorio de Biomembranas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaFil: Galicia, Luciano. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas. Laboratorio de Biomembranas; ArgentinaFil: Ford, Paula. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas. Laboratorio de Biomembranas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaSociedad Argentina de Fisiología2009-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/117816Capurro, Claudia Graciela; Galicia, Luciano; Ford, Paula; Cell Volume Regulation and Aquaporins; Sociedad Argentina de Fisiología; Physiological Mini-reviews; 4; 2; 3-2009; 9-171669-5402CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://pmr.safisiol.org.ar/archive/id/20info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:44:21Zoai:ri.conicet.gov.ar:11336/117816instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:44:21.823CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Cell Volume Regulation and Aquaporins |
title |
Cell Volume Regulation and Aquaporins |
spellingShingle |
Cell Volume Regulation and Aquaporins Capurro, Claudia Graciela CELL VOLUME REGULATION AQUAPORINS RVD RVI |
title_short |
Cell Volume Regulation and Aquaporins |
title_full |
Cell Volume Regulation and Aquaporins |
title_fullStr |
Cell Volume Regulation and Aquaporins |
title_full_unstemmed |
Cell Volume Regulation and Aquaporins |
title_sort |
Cell Volume Regulation and Aquaporins |
dc.creator.none.fl_str_mv |
Capurro, Claudia Graciela Galicia, Luciano Ford, Paula |
author |
Capurro, Claudia Graciela |
author_facet |
Capurro, Claudia Graciela Galicia, Luciano Ford, Paula |
author_role |
author |
author2 |
Galicia, Luciano Ford, Paula |
author2_role |
author author |
dc.subject.none.fl_str_mv |
CELL VOLUME REGULATION AQUAPORINS RVD RVI |
topic |
CELL VOLUME REGULATION AQUAPORINS RVD RVI |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.1 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
In the recent years, the importance of the volume of a given cell has been accepted not only in defining its intracellular osmolality and its shape, but also in defining other cellular functions, such as transepithelial transport, cell migration, cell growth, cell death and the regulation of intracellular metabolism (35). Since most cells have to perform these physiological functions under a variable osmotic stress, cell volume must be carefully regulated. Based on the origin of the disturbance, cell volume changes are frequently classified into two categories: anisosmotic (alterations in extracellular solute concentration) and isosmotic (alterations in intracellular solute concentration) volume changes. Because of the relatively high permeability of the plasma membrane for water, any such gradient results in the immediate flow of water into or out of the cell causing cell swelling or shrinkage. To regulate cell volume, cells use channels and transport systems to flux osmolytes across the plasma membrane, followed by the obligatory movement of water. The current review reflects these developments and focuses on the contributions of aquaporins water channels in regulatory volume processes in a variety of cells. Fil: Capurro, Claudia Graciela. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas. Laboratorio de Biomembranas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina Fil: Galicia, Luciano. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas. Laboratorio de Biomembranas; Argentina Fil: Ford, Paula. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas. Laboratorio de Biomembranas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina |
description |
In the recent years, the importance of the volume of a given cell has been accepted not only in defining its intracellular osmolality and its shape, but also in defining other cellular functions, such as transepithelial transport, cell migration, cell growth, cell death and the regulation of intracellular metabolism (35). Since most cells have to perform these physiological functions under a variable osmotic stress, cell volume must be carefully regulated. Based on the origin of the disturbance, cell volume changes are frequently classified into two categories: anisosmotic (alterations in extracellular solute concentration) and isosmotic (alterations in intracellular solute concentration) volume changes. Because of the relatively high permeability of the plasma membrane for water, any such gradient results in the immediate flow of water into or out of the cell causing cell swelling or shrinkage. To regulate cell volume, cells use channels and transport systems to flux osmolytes across the plasma membrane, followed by the obligatory movement of water. The current review reflects these developments and focuses on the contributions of aquaporins water channels in regulatory volume processes in a variety of cells. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-03 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/117816 Capurro, Claudia Graciela; Galicia, Luciano; Ford, Paula; Cell Volume Regulation and Aquaporins; Sociedad Argentina de Fisiología; Physiological Mini-reviews; 4; 2; 3-2009; 9-17 1669-5402 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/117816 |
identifier_str_mv |
Capurro, Claudia Graciela; Galicia, Luciano; Ford, Paula; Cell Volume Regulation and Aquaporins; Sociedad Argentina de Fisiología; Physiological Mini-reviews; 4; 2; 3-2009; 9-17 1669-5402 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/https://pmr.safisiol.org.ar/archive/id/20 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
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openAccess |
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https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
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application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Sociedad Argentina de Fisiología |
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Sociedad Argentina de Fisiología |
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reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) |
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Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
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dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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