The effect of age on the heart rate variability of healthy subjects

Autores
Garavaglia, Leopoldo; Gulich, Damián; Defeo, Magdalena Maria; Thomas Mailland, Julieta; Irurzun, Isabel María
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In this work we study the characteristics of heart rate variability (HRV) as a function of age and gender. Our analysis covers a wider age range than that studied so far. It includes results previously reported in the literature and reveals behaviours not reported before. We can establish basic scale relationships in different HRV measurements. The mean value of the RR intervals shows a power-law behaviour independent of gender. Magnitudes such as the standard deviation or pNN50 show abrupt changes at around the age of 12 years, and above that age they show gender dependence, which mainly affects short-time (or high frequency) scales. We present a unified analysis for the calculation of the non-linear α and β parameters. Both parameters depend on age; they increase in the extremes of life and reach a minimum at around one year of age. These gender-independent changes occur at low frequencies and in scale ranges that depend on age. The results obtained in this work are discussed in terms of the effects of basal metabolic rate, hormonal regulation, and neuronal activity on heart rate variability. This work finally discusses how these findings influence the interpretation of HRV measurements from records of different lengths.
Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas
Materia
Ciencias Médicas
Electrocardiography
Polynomials
Age distribution
Heart rate
Behavior
Time domain analysis
Computer software
Physical activity
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/132551
Acceder
id SEDICI_8d7bf90a2cd42a2962aa668073372ef7
oai_identifier_str oai:sedici.unlp.edu.ar:10915/132551
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling The effect of age on the heart rate variability of healthy subjectsGaravaglia, LeopoldoGulich, DamiánDefeo, Magdalena MariaThomas Mailland, JulietaIrurzun, Isabel MaríaCiencias MédicasElectrocardiographyPolynomialsAge distributionHeart rateBehaviorTime domain analysisComputer softwarePhysical activityIn this work we study the characteristics of heart rate variability (HRV) as a function of age and gender. Our analysis covers a wider age range than that studied so far. It includes results previously reported in the literature and reveals behaviours not reported before. We can establish basic scale relationships in different HRV measurements. The mean value of the RR intervals shows a power-law behaviour independent of gender. Magnitudes such as the standard deviation or pNN50 show abrupt changes at around the age of 12 years, and above that age they show gender dependence, which mainly affects short-time (or high frequency) scales. We present a unified analysis for the calculation of the non-linear α and β parameters. Both parameters depend on age; they increase in the extremes of life and reach a minimum at around one year of age. These gender-independent changes occur at low frequencies and in scale ranges that depend on age. The results obtained in this work are discussed in terms of the effects of basal metabolic rate, hormonal regulation, and neuronal activity on heart rate variability. This work finally discusses how these findings influence the interpretation of HRV measurements from records of different lengths.Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://sedici.unlp.edu.ar/handle/10915/132551enginfo:eu-repo/semantics/altIdentifier/issn/1932-6203info:eu-repo/semantics/altIdentifier/doi/10.1371/journal.pone.0255894info:eu-repo/semantics/altIdentifier/pmid/34624048info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:32:12Zoai:sedici.unlp.edu.ar:10915/132551Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:32:13.166SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv The effect of age on the heart rate variability of healthy subjects
title The effect of age on the heart rate variability of healthy subjects
spellingShingle The effect of age on the heart rate variability of healthy subjects
Garavaglia, Leopoldo
Ciencias Médicas
Electrocardiography
Polynomials
Age distribution
Heart rate
Behavior
Time domain analysis
Computer software
Physical activity
title_short The effect of age on the heart rate variability of healthy subjects
title_full The effect of age on the heart rate variability of healthy subjects
title_fullStr The effect of age on the heart rate variability of healthy subjects
title_full_unstemmed The effect of age on the heart rate variability of healthy subjects
title_sort The effect of age on the heart rate variability of healthy subjects
dc.creator.none.fl_str_mv Garavaglia, Leopoldo
Gulich, Damián
Defeo, Magdalena Maria
Thomas Mailland, Julieta
Irurzun, Isabel María
author Garavaglia, Leopoldo
author_facet Garavaglia, Leopoldo
Gulich, Damián
Defeo, Magdalena Maria
Thomas Mailland, Julieta
Irurzun, Isabel María
author_role author
author2 Gulich, Damián
Defeo, Magdalena Maria
Thomas Mailland, Julieta
Irurzun, Isabel María
author2_role author
author
author
author
dc.subject.none.fl_str_mv Ciencias Médicas
Electrocardiography
Polynomials
Age distribution
Heart rate
Behavior
Time domain analysis
Computer software
Physical activity
topic Ciencias Médicas
Electrocardiography
Polynomials
Age distribution
Heart rate
Behavior
Time domain analysis
Computer software
Physical activity
dc.description.none.fl_txt_mv In this work we study the characteristics of heart rate variability (HRV) as a function of age and gender. Our analysis covers a wider age range than that studied so far. It includes results previously reported in the literature and reveals behaviours not reported before. We can establish basic scale relationships in different HRV measurements. The mean value of the RR intervals shows a power-law behaviour independent of gender. Magnitudes such as the standard deviation or pNN50 show abrupt changes at around the age of 12 years, and above that age they show gender dependence, which mainly affects short-time (or high frequency) scales. We present a unified analysis for the calculation of the non-linear α and β parameters. Both parameters depend on age; they increase in the extremes of life and reach a minimum at around one year of age. These gender-independent changes occur at low frequencies and in scale ranges that depend on age. The results obtained in this work are discussed in terms of the effects of basal metabolic rate, hormonal regulation, and neuronal activity on heart rate variability. This work finally discusses how these findings influence the interpretation of HRV measurements from records of different lengths.
Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas
description In this work we study the characteristics of heart rate variability (HRV) as a function of age and gender. Our analysis covers a wider age range than that studied so far. It includes results previously reported in the literature and reveals behaviours not reported before. We can establish basic scale relationships in different HRV measurements. The mean value of the RR intervals shows a power-law behaviour independent of gender. Magnitudes such as the standard deviation or pNN50 show abrupt changes at around the age of 12 years, and above that age they show gender dependence, which mainly affects short-time (or high frequency) scales. We present a unified analysis for the calculation of the non-linear α and β parameters. Both parameters depend on age; they increase in the extremes of life and reach a minimum at around one year of age. These gender-independent changes occur at low frequencies and in scale ranges that depend on age. The results obtained in this work are discussed in terms of the effects of basal metabolic rate, hormonal regulation, and neuronal activity on heart rate variability. This work finally discusses how these findings influence the interpretation of HRV measurements from records of different lengths.
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/132551
url http://sedici.unlp.edu.ar/handle/10915/132551
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/1932-6203
info:eu-repo/semantics/altIdentifier/doi/10.1371/journal.pone.0255894
info:eu-repo/semantics/altIdentifier/pmid/34624048
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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