The use of cyclophosphamide as an enhancer of the vaccine against foot-and-mouth disease

Autores
Portiansky, Enrique Leo; González, Pedro Horacio; Laguens, Rubén P.
Año de publicación
1996
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The immunization of biungulate animals with killed foot-and-mouth disease virus (FMDV) requires periodic vaccinations due to a low vaccine immunogenicity. Therefore, FMDV antigens need to be combined with adjuvants such as aluminum hydroxide, saponin or oil emulsions. Animal handling for periodic inoculations, and the repeated doses of vaccines that have to be administered increase the commercialization costs. Moreover, the use of adjuvants may induce adverse effects.
Facultad de Ciencias Veterinarias
Materia
Veterinaria
Cyclophosphamide
foot-and-mouth disease
adjuvant
vaccine
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/139612

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network_name_str SEDICI (UNLP)
spelling The use of cyclophosphamide as an enhancer of the vaccine against foot-and-mouth diseasePortiansky, Enrique LeoGonzález, Pedro HoracioLaguens, Rubén P.VeterinariaCyclophosphamidefoot-and-mouth diseaseadjuvantvaccineThe immunization of biungulate animals with killed foot-and-mouth disease virus (FMDV) requires periodic vaccinations due to a low vaccine immunogenicity. Therefore, FMDV antigens need to be combined with adjuvants such as aluminum hydroxide, saponin or oil emulsions. Animal handling for periodic inoculations, and the repeated doses of vaccines that have to be administered increase the commercialization costs. Moreover, the use of adjuvants may induce adverse effects.Facultad de Ciencias Veterinarias1996-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf605-607http://sedici.unlp.edu.ar/handle/10915/139612enginfo:eu-repo/semantics/altIdentifier/issn/0014-4754info:eu-repo/semantics/altIdentifier/issn/1420-9071info:eu-repo/semantics/altIdentifier/issn/1420-682xinfo:eu-repo/semantics/altIdentifier/doi/10.1007/bf01969738info:eu-repo/semantics/altIdentifier/pmid/8698098info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-11-05T13:11:25Zoai:sedici.unlp.edu.ar:10915/139612Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-11-05 13:11:26.083SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv The use of cyclophosphamide as an enhancer of the vaccine against foot-and-mouth disease
title The use of cyclophosphamide as an enhancer of the vaccine against foot-and-mouth disease
spellingShingle The use of cyclophosphamide as an enhancer of the vaccine against foot-and-mouth disease
Portiansky, Enrique Leo
Veterinaria
Cyclophosphamide
foot-and-mouth disease
adjuvant
vaccine
title_short The use of cyclophosphamide as an enhancer of the vaccine against foot-and-mouth disease
title_full The use of cyclophosphamide as an enhancer of the vaccine against foot-and-mouth disease
title_fullStr The use of cyclophosphamide as an enhancer of the vaccine against foot-and-mouth disease
title_full_unstemmed The use of cyclophosphamide as an enhancer of the vaccine against foot-and-mouth disease
title_sort The use of cyclophosphamide as an enhancer of the vaccine against foot-and-mouth disease
dc.creator.none.fl_str_mv Portiansky, Enrique Leo
González, Pedro Horacio
Laguens, Rubén P.
author Portiansky, Enrique Leo
author_facet Portiansky, Enrique Leo
González, Pedro Horacio
Laguens, Rubén P.
author_role author
author2 González, Pedro Horacio
Laguens, Rubén P.
author2_role author
author
dc.subject.none.fl_str_mv Veterinaria
Cyclophosphamide
foot-and-mouth disease
adjuvant
vaccine
topic Veterinaria
Cyclophosphamide
foot-and-mouth disease
adjuvant
vaccine
dc.description.none.fl_txt_mv The immunization of biungulate animals with killed foot-and-mouth disease virus (FMDV) requires periodic vaccinations due to a low vaccine immunogenicity. Therefore, FMDV antigens need to be combined with adjuvants such as aluminum hydroxide, saponin or oil emulsions. Animal handling for periodic inoculations, and the repeated doses of vaccines that have to be administered increase the commercialization costs. Moreover, the use of adjuvants may induce adverse effects.
Facultad de Ciencias Veterinarias
description The immunization of biungulate animals with killed foot-and-mouth disease virus (FMDV) requires periodic vaccinations due to a low vaccine immunogenicity. Therefore, FMDV antigens need to be combined with adjuvants such as aluminum hydroxide, saponin or oil emulsions. Animal handling for periodic inoculations, and the repeated doses of vaccines that have to be administered increase the commercialization costs. Moreover, the use of adjuvants may induce adverse effects.
publishDate 1996
dc.date.none.fl_str_mv 1996-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/139612
url http://sedici.unlp.edu.ar/handle/10915/139612
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/0014-4754
info:eu-repo/semantics/altIdentifier/issn/1420-9071
info:eu-repo/semantics/altIdentifier/issn/1420-682x
info:eu-repo/semantics/altIdentifier/doi/10.1007/bf01969738
info:eu-repo/semantics/altIdentifier/pmid/8698098
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.format.none.fl_str_mv application/pdf
605-607
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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