Genetic and phenotypic variability of iris color in Buenos Aires population

Autores
Hohl, Diana María; Bezus, Brenda; Ratowiecki, Julia; Catanesi, Cecilia Inés
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The aim of this work was to describe the phenotypic and genotypic variability related to iris color for the population of Buenos Aires province (Argentina), and to assess the usefulness of current methods of analysis for this country. We studied five Single Nucleotide Polymorphisms (SNPs) included in the IrisPlex kit, in 118 individuals, and we quantified eye color with Digital Iris Analysis Tool. The markers fit Hardy-Weinberg equilibrium for the whole sample, but not for rs12913832 within the group of brown eyes (LR=8.429; p=0.004). We found a remarkable association of HERC2 rs12913832 GG with blue color (p < 0.01) but the other markers did not show any association with iris color. The results for the Buenos Aires population differ from those of other populations of the world for these polymorphisms (p < 0,01). The differences we found might respond to the admixed ethnic composition of Argentina; therefore, methods of analysis used in European populations should be carefully applied when studying the population of Argentina. These findings reaffirm the importance of this investigation in the Argentinian population for people identification based on iris color.
Facultad de Ciencias Exactas
Instituto Multidisciplinario de Biología Celular
Facultad de Ciencias Médicas
Materia
Ciencias Exactas
Population genetics
iris color
forensic genetics
phenotype determination
Argentinian population
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/107886
Acceder
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oai_identifier_str oai:sedici.unlp.edu.ar:10915/107886
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Genetic and phenotypic variability of iris color in Buenos Aires populationHohl, Diana MaríaBezus, BrendaRatowiecki, JuliaCatanesi, Cecilia InésCiencias ExactasPopulation geneticsiris colorforensic geneticsphenotype determinationArgentinian populationThe aim of this work was to describe the phenotypic and genotypic variability related to iris color for the population of Buenos Aires province (Argentina), and to assess the usefulness of current methods of analysis for this country. We studied five Single Nucleotide Polymorphisms (SNPs) included in the IrisPlex kit, in 118 individuals, and we quantified eye color with Digital Iris Analysis Tool. The markers fit Hardy-Weinberg equilibrium for the whole sample, but not for rs12913832 within the group of brown eyes (LR=8.429; p=0.004). We found a remarkable association of <i>HERC2</i> rs12913832 GG with blue color (p < 0.01) but the other markers did not show any association with iris color. The results for the Buenos Aires population differ from those of other populations of the world for these polymorphisms (p < 0,01). The differences we found might respond to the admixed ethnic composition of Argentina; therefore, methods of analysis used in European populations should be carefully applied when studying the population of Argentina. These findings reaffirm the importance of this investigation in the Argentinian population for people identification based on iris color.Facultad de Ciencias ExactasInstituto Multidisciplinario de Biología CelularFacultad de Ciencias Médicas2018info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf50-58http://sedici.unlp.edu.ar/handle/10915/107886enginfo:eu-repo/semantics/altIdentifier/url/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5901501&blobtype=pdfinfo:eu-repo/semantics/altIdentifier/issn/1678-4685info:eu-repo/semantics/altIdentifier/pmid/29658972info:eu-repo/semantics/altIdentifier/doi/10.1590/1678-4685-gmb-2017-0175info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:23:52Zoai:sedici.unlp.edu.ar:10915/107886Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:23:52.832SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Genetic and phenotypic variability of iris color in Buenos Aires population
title Genetic and phenotypic variability of iris color in Buenos Aires population
spellingShingle Genetic and phenotypic variability of iris color in Buenos Aires population
Hohl, Diana María
Ciencias Exactas
Population genetics
iris color
forensic genetics
phenotype determination
Argentinian population
title_short Genetic and phenotypic variability of iris color in Buenos Aires population
title_full Genetic and phenotypic variability of iris color in Buenos Aires population
title_fullStr Genetic and phenotypic variability of iris color in Buenos Aires population
title_full_unstemmed Genetic and phenotypic variability of iris color in Buenos Aires population
title_sort Genetic and phenotypic variability of iris color in Buenos Aires population
dc.creator.none.fl_str_mv Hohl, Diana María
Bezus, Brenda
Ratowiecki, Julia
Catanesi, Cecilia Inés
author Hohl, Diana María
author_facet Hohl, Diana María
Bezus, Brenda
Ratowiecki, Julia
Catanesi, Cecilia Inés
author_role author
author2 Bezus, Brenda
Ratowiecki, Julia
Catanesi, Cecilia Inés
author2_role author
author
author
dc.subject.none.fl_str_mv Ciencias Exactas
Population genetics
iris color
forensic genetics
phenotype determination
Argentinian population
topic Ciencias Exactas
Population genetics
iris color
forensic genetics
phenotype determination
Argentinian population
dc.description.none.fl_txt_mv The aim of this work was to describe the phenotypic and genotypic variability related to iris color for the population of Buenos Aires province (Argentina), and to assess the usefulness of current methods of analysis for this country. We studied five Single Nucleotide Polymorphisms (SNPs) included in the IrisPlex kit, in 118 individuals, and we quantified eye color with Digital Iris Analysis Tool. The markers fit Hardy-Weinberg equilibrium for the whole sample, but not for rs12913832 within the group of brown eyes (LR=8.429; p=0.004). We found a remarkable association of <i>HERC2</i> rs12913832 GG with blue color (p < 0.01) but the other markers did not show any association with iris color. The results for the Buenos Aires population differ from those of other populations of the world for these polymorphisms (p < 0,01). The differences we found might respond to the admixed ethnic composition of Argentina; therefore, methods of analysis used in European populations should be carefully applied when studying the population of Argentina. These findings reaffirm the importance of this investigation in the Argentinian population for people identification based on iris color.
Facultad de Ciencias Exactas
Instituto Multidisciplinario de Biología Celular
Facultad de Ciencias Médicas
description The aim of this work was to describe the phenotypic and genotypic variability related to iris color for the population of Buenos Aires province (Argentina), and to assess the usefulness of current methods of analysis for this country. We studied five Single Nucleotide Polymorphisms (SNPs) included in the IrisPlex kit, in 118 individuals, and we quantified eye color with Digital Iris Analysis Tool. The markers fit Hardy-Weinberg equilibrium for the whole sample, but not for rs12913832 within the group of brown eyes (LR=8.429; p=0.004). We found a remarkable association of <i>HERC2</i> rs12913832 GG with blue color (p < 0.01) but the other markers did not show any association with iris color. The results for the Buenos Aires population differ from those of other populations of the world for these polymorphisms (p < 0,01). The differences we found might respond to the admixed ethnic composition of Argentina; therefore, methods of analysis used in European populations should be carefully applied when studying the population of Argentina. These findings reaffirm the importance of this investigation in the Argentinian population for people identification based on iris color.
publishDate 2018
dc.date.none.fl_str_mv 2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/107886
url http://sedici.unlp.edu.ar/handle/10915/107886
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5901501&blobtype=pdf
info:eu-repo/semantics/altIdentifier/issn/1678-4685
info:eu-repo/semantics/altIdentifier/pmid/29658972
info:eu-repo/semantics/altIdentifier/doi/10.1590/1678-4685-gmb-2017-0175
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.format.none.fl_str_mv application/pdf
50-58
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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