A GHEP-ISFG collaborative study on the genetic variation of 38 autosomal indels for human identification in different continental populations

Autores
Pereira, R.; Alves, C.; Aler, M.; Amorim, A.; Arévalo, C.; Betancor, E.; Braganholi, D.; Bravo, M. L.; Brito, P.; Builes, J. J.; Burgos, G.; Carvalho, E. F.; Castillo, A.; Catanesi, Cecilia Inés; Cicarelli, R. M. B.; Coufalova, P.; Dario, P.; D’Amato, M. E.; Davison, S.; Ferragut, J.; Fondevila, M.; Furfurov, S.; García, O.; Gaviria, A.; Gomes, I.; González, E.; Gonzalez-Liñan, A.; Gross, T. E.; Hernández, A.; Huang, Q.; Jiménez, S.; Jobim, L. F.; López-Parra, A. M.; Marino, M.; Marques, S.; Martínez-Cortés, G.; Masciovecchio, V.; Parra, D.; Penacino, G.; Pinheiro, M. F.; Porto, M. J.; Posada, Y.; Restrepo, C.; Ribeiro, T.; Rubio, L.; Sala, A.; Santurtún, A.; Solís, L. S.; Souto, L.; Streitemberger, E.; Torres, A.; Vilela-Lamego, C.; Yunis, J. J.; Yurrebaso, I.; Gusmão, L.
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A collaborative effort was carried out by the Spanish and Portuguese Speaking Working Group of the International Society for Forensic Genetics (GHEP-ISFG) to promote knowledge exchange between associate laboratories interested in the implementation of indel-based methodologies and build allele frequency databases of 38 indels for forensic applications. These databases include populations from different countries that are relevant for identification and kinship investigations undertaken by the participating laboratories. Before compiling population data, participants were asked to type the 38 indels in blind samples from annual GHEP-ISFG proficiency tests, using an amplification protocol previously described. Only laboratories that reported correct results contributed with population data to this study. A total of 5839 samples were genotyped from 45 different populations from Africa, America, East Asia, Europe and Middle East. Population differentiation analysis showed significant differences between most populations studied from Africa and America, as well as between two Asian populations from China and East Timor. Low FST values were detected among most European populations. Overall diversities and parameters of forensic efficiency were high in populations from all continents.
Instituto Multidisciplinario de Biología Celular
Facultad de Ciencias Naturales y Museo
Materia
Ciencias Exactas
Medicina
Forensic genetics
Human identification
Insertion deletion (indel)
Allele frequency databases
Population data
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/128519

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oai_identifier_str oai:sedici.unlp.edu.ar:10915/128519
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling A GHEP-ISFG collaborative study on the genetic variation of 38 autosomal indels for human identification in different continental populationsPereira, R.Alves, C.Aler, M.Amorim, A.Arévalo, C.Betancor, E.Braganholi, D.Bravo, M. L.Brito, P.Builes, J. J.Burgos, G.Carvalho, E. F.Castillo, A.Catanesi, Cecilia InésCicarelli, R. M. B.Coufalova, P.Dario, P.D’Amato, M. E.Davison, S.Ferragut, J.Fondevila, M.Furfurov, S.García, O.Gaviria, A.Gomes, I.González, E.Gonzalez-Liñan, A.Gross, T. E.Hernández, A.Huang, Q.Jiménez, S.Jobim, L. F.López-Parra, A. M.Marino, M.Marques, S.Martínez-Cortés, G.Masciovecchio, V.Parra, D.Penacino, G.Pinheiro, M. F.Porto, M. J.Posada, Y.Restrepo, C.Ribeiro, T.Rubio, L.Sala, A.Santurtún, A.Solís, L. S.Souto, L.Streitemberger, E.Torres, A.Vilela-Lamego, C.Yunis, J. J.Yurrebaso, I.Gusmão, L.Ciencias ExactasMedicinaForensic geneticsHuman identificationInsertion deletion (indel)Allele frequency databasesPopulation dataA collaborative effort was carried out by the Spanish and Portuguese Speaking Working Group of the International Society for Forensic Genetics (GHEP-ISFG) to promote knowledge exchange between associate laboratories interested in the implementation of indel-based methodologies and build allele frequency databases of 38 indels for forensic applications. These databases include populations from different countries that are relevant for identification and kinship investigations undertaken by the participating laboratories. Before compiling population data, participants were asked to type the 38 indels in blind samples from annual GHEP-ISFG proficiency tests, using an amplification protocol previously described. Only laboratories that reported correct results contributed with population data to this study. A total of 5839 samples were genotyped from 45 different populations from Africa, America, East Asia, Europe and Middle East. Population differentiation analysis showed significant differences between most populations studied from Africa and America, as well as between two Asian populations from China and East Timor. Low F<sub>ST</sub> values were detected among most European populations. Overall diversities and parameters of forensic efficiency were high in populations from all continents.Instituto Multidisciplinario de Biología CelularFacultad de Ciencias Naturales y Museo2018-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf18-25http://sedici.unlp.edu.ar/handle/10915/128519enginfo:eu-repo/semantics/altIdentifier/issn/1878-0326info:eu-repo/semantics/altIdentifier/issn/1872-4973info:eu-repo/semantics/altIdentifier/pmid/29024923info:eu-repo/semantics/altIdentifier/doi/10.1016/j.fsigen.2017.09.012info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:30:58Zoai:sedici.unlp.edu.ar:10915/128519Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:30:58.939SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv A GHEP-ISFG collaborative study on the genetic variation of 38 autosomal indels for human identification in different continental populations
title A GHEP-ISFG collaborative study on the genetic variation of 38 autosomal indels for human identification in different continental populations
spellingShingle A GHEP-ISFG collaborative study on the genetic variation of 38 autosomal indels for human identification in different continental populations
Pereira, R.
Ciencias Exactas
Medicina
Forensic genetics
Human identification
Insertion deletion (indel)
Allele frequency databases
Population data
title_short A GHEP-ISFG collaborative study on the genetic variation of 38 autosomal indels for human identification in different continental populations
title_full A GHEP-ISFG collaborative study on the genetic variation of 38 autosomal indels for human identification in different continental populations
title_fullStr A GHEP-ISFG collaborative study on the genetic variation of 38 autosomal indels for human identification in different continental populations
title_full_unstemmed A GHEP-ISFG collaborative study on the genetic variation of 38 autosomal indels for human identification in different continental populations
title_sort A GHEP-ISFG collaborative study on the genetic variation of 38 autosomal indels for human identification in different continental populations
dc.creator.none.fl_str_mv Pereira, R.
Alves, C.
Aler, M.
Amorim, A.
Arévalo, C.
Betancor, E.
Braganholi, D.
Bravo, M. L.
Brito, P.
Builes, J. J.
Burgos, G.
Carvalho, E. F.
Castillo, A.
Catanesi, Cecilia Inés
Cicarelli, R. M. B.
Coufalova, P.
Dario, P.
D’Amato, M. E.
Davison, S.
Ferragut, J.
Fondevila, M.
Furfurov, S.
García, O.
Gaviria, A.
Gomes, I.
González, E.
Gonzalez-Liñan, A.
Gross, T. E.
Hernández, A.
Huang, Q.
Jiménez, S.
Jobim, L. F.
López-Parra, A. M.
Marino, M.
Marques, S.
Martínez-Cortés, G.
Masciovecchio, V.
Parra, D.
Penacino, G.
Pinheiro, M. F.
Porto, M. J.
Posada, Y.
Restrepo, C.
Ribeiro, T.
Rubio, L.
Sala, A.
Santurtún, A.
Solís, L. S.
Souto, L.
Streitemberger, E.
Torres, A.
Vilela-Lamego, C.
Yunis, J. J.
Yurrebaso, I.
Gusmão, L.
author Pereira, R.
author_facet Pereira, R.
Alves, C.
Aler, M.
Amorim, A.
Arévalo, C.
Betancor, E.
Braganholi, D.
Bravo, M. L.
Brito, P.
Builes, J. J.
Burgos, G.
Carvalho, E. F.
Castillo, A.
Catanesi, Cecilia Inés
Cicarelli, R. M. B.
Coufalova, P.
Dario, P.
D’Amato, M. E.
Davison, S.
Ferragut, J.
Fondevila, M.
Furfurov, S.
García, O.
Gaviria, A.
Gomes, I.
González, E.
Gonzalez-Liñan, A.
Gross, T. E.
Hernández, A.
Huang, Q.
Jiménez, S.
Jobim, L. F.
López-Parra, A. M.
Marino, M.
Marques, S.
Martínez-Cortés, G.
Masciovecchio, V.
Parra, D.
Penacino, G.
Pinheiro, M. F.
Porto, M. J.
Posada, Y.
Restrepo, C.
Ribeiro, T.
Rubio, L.
Sala, A.
Santurtún, A.
Solís, L. S.
Souto, L.
Streitemberger, E.
Torres, A.
Vilela-Lamego, C.
Yunis, J. J.
Yurrebaso, I.
Gusmão, L.
author_role author
author2 Alves, C.
Aler, M.
Amorim, A.
Arévalo, C.
Betancor, E.
Braganholi, D.
Bravo, M. L.
Brito, P.
Builes, J. J.
Burgos, G.
Carvalho, E. F.
Castillo, A.
Catanesi, Cecilia Inés
Cicarelli, R. M. B.
Coufalova, P.
Dario, P.
D’Amato, M. E.
Davison, S.
Ferragut, J.
Fondevila, M.
Furfurov, S.
García, O.
Gaviria, A.
Gomes, I.
González, E.
Gonzalez-Liñan, A.
Gross, T. E.
Hernández, A.
Huang, Q.
Jiménez, S.
Jobim, L. F.
López-Parra, A. M.
Marino, M.
Marques, S.
Martínez-Cortés, G.
Masciovecchio, V.
Parra, D.
Penacino, G.
Pinheiro, M. F.
Porto, M. J.
Posada, Y.
Restrepo, C.
Ribeiro, T.
Rubio, L.
Sala, A.
Santurtún, A.
Solís, L. S.
Souto, L.
Streitemberger, E.
Torres, A.
Vilela-Lamego, C.
Yunis, J. J.
Yurrebaso, I.
Gusmão, L.
author2_role author
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author
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author
author
author
author
author
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author
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author
author
author
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author
author
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dc.subject.none.fl_str_mv Ciencias Exactas
Medicina
Forensic genetics
Human identification
Insertion deletion (indel)
Allele frequency databases
Population data
topic Ciencias Exactas
Medicina
Forensic genetics
Human identification
Insertion deletion (indel)
Allele frequency databases
Population data
dc.description.none.fl_txt_mv A collaborative effort was carried out by the Spanish and Portuguese Speaking Working Group of the International Society for Forensic Genetics (GHEP-ISFG) to promote knowledge exchange between associate laboratories interested in the implementation of indel-based methodologies and build allele frequency databases of 38 indels for forensic applications. These databases include populations from different countries that are relevant for identification and kinship investigations undertaken by the participating laboratories. Before compiling population data, participants were asked to type the 38 indels in blind samples from annual GHEP-ISFG proficiency tests, using an amplification protocol previously described. Only laboratories that reported correct results contributed with population data to this study. A total of 5839 samples were genotyped from 45 different populations from Africa, America, East Asia, Europe and Middle East. Population differentiation analysis showed significant differences between most populations studied from Africa and America, as well as between two Asian populations from China and East Timor. Low F<sub>ST</sub> values were detected among most European populations. Overall diversities and parameters of forensic efficiency were high in populations from all continents.
Instituto Multidisciplinario de Biología Celular
Facultad de Ciencias Naturales y Museo
description A collaborative effort was carried out by the Spanish and Portuguese Speaking Working Group of the International Society for Forensic Genetics (GHEP-ISFG) to promote knowledge exchange between associate laboratories interested in the implementation of indel-based methodologies and build allele frequency databases of 38 indels for forensic applications. These databases include populations from different countries that are relevant for identification and kinship investigations undertaken by the participating laboratories. Before compiling population data, participants were asked to type the 38 indels in blind samples from annual GHEP-ISFG proficiency tests, using an amplification protocol previously described. Only laboratories that reported correct results contributed with population data to this study. A total of 5839 samples were genotyped from 45 different populations from Africa, America, East Asia, Europe and Middle East. Population differentiation analysis showed significant differences between most populations studied from Africa and America, as well as between two Asian populations from China and East Timor. Low F<sub>ST</sub> values were detected among most European populations. Overall diversities and parameters of forensic efficiency were high in populations from all continents.
publishDate 2018
dc.date.none.fl_str_mv 2018-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/128519
url http://sedici.unlp.edu.ar/handle/10915/128519
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/1878-0326
info:eu-repo/semantics/altIdentifier/issn/1872-4973
info:eu-repo/semantics/altIdentifier/pmid/29024923
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.fsigen.2017.09.012
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
18-25
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
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reponame_str SEDICI (UNLP)
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instname_str Universidad Nacional de La Plata
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institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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