Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control

Autores
Reynaldi, Francisco José; Albo, Graciela Noemí; Avellaneda, Elisa; Rule, Roberto
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
We compared the kinetic behaviour of tylosin administered to beehives by dusting or paper-pack placement through three treatment protocols (D, PP, CONTROL). D (dusting): tylosin, divided in four portions, was sprinkled over the ends of the hives' top bars weekly for four weeks (n=3); PP (paper-pack placement): tylosin in paper packs was administered at two-week intervals (n=3); CONTROL (control): the hives were left untreated (n=3). In every inspection, from each of the nine hives, fifty young (2-day-old) larvae were sampled for drug analysis. The concentration of tylosin in the young larvae was determined by a microbiological assay with Geobacillus stearothermophilus ATCC 12980 as test organism. The (mean±SD) maximum concentration (Cmax) for D was 136.0±194.0 and for PP – 144.0±187.4 μg/mL; the time to reach Cmax (tmax) was 1.5±0.9 h for D and 1.8 ± 1.8 h for PP. The area under the tylosin behaviour kinetics curve between 0–1392 h with D was 308.7±185.2 and with PP: 326.4±141.0 μg/h/mL, indicating no statistical difference between the treatments (P>0.05). The shorter duration of paper-pack-administered tylosin observed in the larvae implied a lower risk of antibiotic residues in the resulting honey.
Facultad de Ciencias Agrarias y Forestales
Materia
Ciencias Veterinarias
american foulbrood
beehives
kinetics
tylosin
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-nd/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/78149
Acceder
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network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood controlReynaldi, Francisco JoséAlbo, Graciela NoemíAvellaneda, ElisaRule, RobertoCiencias Veterinariasamerican foulbroodbeehiveskineticstylosinWe compared the kinetic behaviour of tylosin administered to beehives by dusting or paper-pack placement through three treatment protocols (D, PP, CONTROL). D (dusting): tylosin, divided in four portions, was sprinkled over the ends of the hives' top bars weekly for four weeks (n=3); PP (paper-pack placement): tylosin in paper packs was administered at two-week intervals (n=3); CONTROL (control): the hives were left untreated (n=3). In every inspection, from each of the nine hives, fifty young (2-day-old) larvae were sampled for drug analysis. The concentration of tylosin in the young larvae was determined by a microbiological assay with Geobacillus stearothermophilus ATCC 12980 as test organism. The (mean±SD) maximum concentration (Cmax) for D was 136.0±194.0 and for PP – 144.0±187.4 μg/mL; the time to reach Cmax (tmax) was 1.5±0.9 h for D and 1.8 ± 1.8 h for PP. The area under the tylosin behaviour kinetics curve between 0–1392 h with D was 308.7±185.2 and with PP: 326.4±141.0 μg/h/mL, indicating no statistical difference between the treatments (P>0.05). The shorter duration of paper-pack-administered tylosin observed in the larvae implied a lower risk of antibiotic residues in the resulting honey.Facultad de Ciencias Agrarias y Forestales2017-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf264-270http://sedici.unlp.edu.ar/handle/10915/78149enginfo:eu-repo/semantics/altIdentifier/issn/1313-3543info:eu-repo/semantics/altIdentifier/doi/10.15547/bjvm.1024info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/4.0/Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-03T10:46:07Zoai:sedici.unlp.edu.ar:10915/78149Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-03 10:46:07.348SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control
title Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control
spellingShingle Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control
Reynaldi, Francisco José
Ciencias Veterinarias
american foulbrood
beehives
kinetics
tylosin
title_short Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control
title_full Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control
title_fullStr Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control
title_full_unstemmed Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control
title_sort Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control
dc.creator.none.fl_str_mv Reynaldi, Francisco José
Albo, Graciela Noemí
Avellaneda, Elisa
Rule, Roberto
author Reynaldi, Francisco José
author_facet Reynaldi, Francisco José
Albo, Graciela Noemí
Avellaneda, Elisa
Rule, Roberto
author_role author
author2 Albo, Graciela Noemí
Avellaneda, Elisa
Rule, Roberto
author2_role author
author
author
dc.subject.none.fl_str_mv Ciencias Veterinarias
american foulbrood
beehives
kinetics
tylosin
topic Ciencias Veterinarias
american foulbrood
beehives
kinetics
tylosin
dc.description.none.fl_txt_mv We compared the kinetic behaviour of tylosin administered to beehives by dusting or paper-pack placement through three treatment protocols (D, PP, CONTROL). D (dusting): tylosin, divided in four portions, was sprinkled over the ends of the hives' top bars weekly for four weeks (n=3); PP (paper-pack placement): tylosin in paper packs was administered at two-week intervals (n=3); CONTROL (control): the hives were left untreated (n=3). In every inspection, from each of the nine hives, fifty young (2-day-old) larvae were sampled for drug analysis. The concentration of tylosin in the young larvae was determined by a microbiological assay with Geobacillus stearothermophilus ATCC 12980 as test organism. The (mean±SD) maximum concentration (Cmax) for D was 136.0±194.0 and for PP – 144.0±187.4 μg/mL; the time to reach Cmax (tmax) was 1.5±0.9 h for D and 1.8 ± 1.8 h for PP. The area under the tylosin behaviour kinetics curve between 0–1392 h with D was 308.7±185.2 and with PP: 326.4±141.0 μg/h/mL, indicating no statistical difference between the treatments (P>0.05). The shorter duration of paper-pack-administered tylosin observed in the larvae implied a lower risk of antibiotic residues in the resulting honey.
Facultad de Ciencias Agrarias y Forestales
description We compared the kinetic behaviour of tylosin administered to beehives by dusting or paper-pack placement through three treatment protocols (D, PP, CONTROL). D (dusting): tylosin, divided in four portions, was sprinkled over the ends of the hives' top bars weekly for four weeks (n=3); PP (paper-pack placement): tylosin in paper packs was administered at two-week intervals (n=3); CONTROL (control): the hives were left untreated (n=3). In every inspection, from each of the nine hives, fifty young (2-day-old) larvae were sampled for drug analysis. The concentration of tylosin in the young larvae was determined by a microbiological assay with Geobacillus stearothermophilus ATCC 12980 as test organism. The (mean±SD) maximum concentration (Cmax) for D was 136.0±194.0 and for PP – 144.0±187.4 μg/mL; the time to reach Cmax (tmax) was 1.5±0.9 h for D and 1.8 ± 1.8 h for PP. The area under the tylosin behaviour kinetics curve between 0–1392 h with D was 308.7±185.2 and with PP: 326.4±141.0 μg/h/mL, indicating no statistical difference between the treatments (P>0.05). The shorter duration of paper-pack-administered tylosin observed in the larvae implied a lower risk of antibiotic residues in the resulting honey.
publishDate 2017
dc.date.none.fl_str_mv 2017-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/78149
url http://sedici.unlp.edu.ar/handle/10915/78149
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/1313-3543
info:eu-repo/semantics/altIdentifier/doi/10.15547/bjvm.1024
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
dc.format.none.fl_str_mv application/pdf
264-270
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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