Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for American foulbrood control

Autores
Reynaldi, Francisco José; Albo, G.; Avellaneda, E.; Rule, R.
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
We compared the kinetic behaviour of tylosin administered to beehives by dusting or paper-pack placement through three treatment protocols (D, PP, CONTROL). D (dusting): tylosin, divided in four portions, was sprinkled over the ends of the hives' top bars weekly for four weeks (n=3); PP (paper-pack placement): tylosin in paper packs was administered at two-week intervals (n=3); CONTROL (control): the hives were left untreated (n=3). In every inspection, from each of the nine hives, fifty young (2-day-old) larvae were sampled for drug analysis. The concentration of tylosin in the young larvae was determined by a microbiological assay with Geobacillus stearothermophilus ATCC 12980 as test organism. The (mean±SD) maximum concentration (Cmax) for D was 136.0±194.0 and for PP – 144.0±187.4 μg/mL; the time to reach Cmax (tmax) was 1.5±0.9 h for D and 1.8 ± 1.8 h for PP. The area under the tylosin behaviour kinetics curve between 0–1392 h with D was 308.7±185.2 and with PP: 326.4±141.0 μg/h/mL, indicating no statistical difference between the treatments (P>0.05). The shorter duration of paper-pack-administered tylosin observed in the larvae implied a lower risk of antibiotic residues in the resulting honey.
Fil: Reynaldi, Francisco José. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Albo, G.. Universidad Nacional de La Plata. Facultad de Ciencias Agrarias y Forestales; Argentina
Fil: Avellaneda, E.. Universidad Nacional de La Plata. Facultad de Ciencias Agrarias y Forestales; Argentina
Fil: Rule, R.. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina
Materia
AMERICAN FOULBROOD
BEEHIVES
KINETICS
TYLOSIN
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/54744
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/54744
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for American foulbrood controlReynaldi, Francisco JoséAlbo, G.Avellaneda, E.Rule, R.AMERICAN FOULBROODBEEHIVESKINETICSTYLOSINhttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4We compared the kinetic behaviour of tylosin administered to beehives by dusting or paper-pack placement through three treatment protocols (D, PP, CONTROL). D (dusting): tylosin, divided in four portions, was sprinkled over the ends of the hives' top bars weekly for four weeks (n=3); PP (paper-pack placement): tylosin in paper packs was administered at two-week intervals (n=3); CONTROL (control): the hives were left untreated (n=3). In every inspection, from each of the nine hives, fifty young (2-day-old) larvae were sampled for drug analysis. The concentration of tylosin in the young larvae was determined by a microbiological assay with Geobacillus stearothermophilus ATCC 12980 as test organism. The (mean±SD) maximum concentration (Cmax) for D was 136.0±194.0 and for PP – 144.0±187.4 μg/mL; the time to reach Cmax (tmax) was 1.5±0.9 h for D and 1.8 ± 1.8 h for PP. The area under the tylosin behaviour kinetics curve between 0–1392 h with D was 308.7±185.2 and with PP: 326.4±141.0 μg/h/mL, indicating no statistical difference between the treatments (P>0.05). The shorter duration of paper-pack-administered tylosin observed in the larvae implied a lower risk of antibiotic residues in the resulting honey.Fil: Reynaldi, Francisco José. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Albo, G.. Universidad Nacional de La Plata. Facultad de Ciencias Agrarias y Forestales; ArgentinaFil: Avellaneda, E.. Universidad Nacional de La Plata. Facultad de Ciencias Agrarias y Forestales; ArgentinaFil: Rule, R.. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; ArgentinaTrakia University2016-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/54744Reynaldi, Francisco José; Albo, G.; Avellaneda, E.; Rule, R.; Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for American foulbrood control; Trakia University; Bulgarian Journal of Veterinary Medicine; 20; 3; 7-2016; 264-2701313-3543CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.15547/bjvm.1024info:eu-repo/semantics/altIdentifier/url/http://tru.uni-sz.bg/bjvm/BJVM-September%202017%20p.%20264-270.pdfinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:51:25Zoai:ri.conicet.gov.ar:11336/54744instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:51:26.87CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for American foulbrood control
title Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for American foulbrood control
spellingShingle Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for American foulbrood control
Reynaldi, Francisco José
AMERICAN FOULBROOD
BEEHIVES
KINETICS
TYLOSIN
title_short Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for American foulbrood control
title_full Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for American foulbrood control
title_fullStr Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for American foulbrood control
title_full_unstemmed Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for American foulbrood control
title_sort Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for American foulbrood control
dc.creator.none.fl_str_mv Reynaldi, Francisco José
Albo, G.
Avellaneda, E.
Rule, R.
author Reynaldi, Francisco José
author_facet Reynaldi, Francisco José
Albo, G.
Avellaneda, E.
Rule, R.
author_role author
author2 Albo, G.
Avellaneda, E.
Rule, R.
author2_role author
author
author
dc.subject.none.fl_str_mv AMERICAN FOULBROOD
BEEHIVES
KINETICS
TYLOSIN
topic AMERICAN FOULBROOD
BEEHIVES
KINETICS
TYLOSIN
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv We compared the kinetic behaviour of tylosin administered to beehives by dusting or paper-pack placement through three treatment protocols (D, PP, CONTROL). D (dusting): tylosin, divided in four portions, was sprinkled over the ends of the hives' top bars weekly for four weeks (n=3); PP (paper-pack placement): tylosin in paper packs was administered at two-week intervals (n=3); CONTROL (control): the hives were left untreated (n=3). In every inspection, from each of the nine hives, fifty young (2-day-old) larvae were sampled for drug analysis. The concentration of tylosin in the young larvae was determined by a microbiological assay with Geobacillus stearothermophilus ATCC 12980 as test organism. The (mean±SD) maximum concentration (Cmax) for D was 136.0±194.0 and for PP – 144.0±187.4 μg/mL; the time to reach Cmax (tmax) was 1.5±0.9 h for D and 1.8 ± 1.8 h for PP. The area under the tylosin behaviour kinetics curve between 0–1392 h with D was 308.7±185.2 and with PP: 326.4±141.0 μg/h/mL, indicating no statistical difference between the treatments (P>0.05). The shorter duration of paper-pack-administered tylosin observed in the larvae implied a lower risk of antibiotic residues in the resulting honey.
Fil: Reynaldi, Francisco José. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Albo, G.. Universidad Nacional de La Plata. Facultad de Ciencias Agrarias y Forestales; Argentina
Fil: Avellaneda, E.. Universidad Nacional de La Plata. Facultad de Ciencias Agrarias y Forestales; Argentina
Fil: Rule, R.. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina
description We compared the kinetic behaviour of tylosin administered to beehives by dusting or paper-pack placement through three treatment protocols (D, PP, CONTROL). D (dusting): tylosin, divided in four portions, was sprinkled over the ends of the hives' top bars weekly for four weeks (n=3); PP (paper-pack placement): tylosin in paper packs was administered at two-week intervals (n=3); CONTROL (control): the hives were left untreated (n=3). In every inspection, from each of the nine hives, fifty young (2-day-old) larvae were sampled for drug analysis. The concentration of tylosin in the young larvae was determined by a microbiological assay with Geobacillus stearothermophilus ATCC 12980 as test organism. The (mean±SD) maximum concentration (Cmax) for D was 136.0±194.0 and for PP – 144.0±187.4 μg/mL; the time to reach Cmax (tmax) was 1.5±0.9 h for D and 1.8 ± 1.8 h for PP. The area under the tylosin behaviour kinetics curve between 0–1392 h with D was 308.7±185.2 and with PP: 326.4±141.0 μg/h/mL, indicating no statistical difference between the treatments (P>0.05). The shorter duration of paper-pack-administered tylosin observed in the larvae implied a lower risk of antibiotic residues in the resulting honey.
publishDate 2016
dc.date.none.fl_str_mv 2016-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/54744
Reynaldi, Francisco José; Albo, G.; Avellaneda, E.; Rule, R.; Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for American foulbrood control; Trakia University; Bulgarian Journal of Veterinary Medicine; 20; 3; 7-2016; 264-270
1313-3543
CONICET Digital
CONICET
url http://hdl.handle.net/11336/54744
identifier_str_mv Reynaldi, Francisco José; Albo, G.; Avellaneda, E.; Rule, R.; Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for American foulbrood control; Trakia University; Bulgarian Journal of Veterinary Medicine; 20; 3; 7-2016; 264-270
1313-3543
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.15547/bjvm.1024
info:eu-repo/semantics/altIdentifier/url/http://tru.uni-sz.bg/bjvm/BJVM-September%202017%20p.%20264-270.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Trakia University
publisher.none.fl_str_mv Trakia University
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269093594398720
score 13.13397

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