Lectin-Recognizable MOF Glyconanoparticles: Supramolecular Glycosylation of ZIF-8 Nanocrystals by Sugar-Based Surfactants

Autores
Giménez, Rodrigo Esteban; Piccinini, Esteban; Azzaroni, Omar; Rafti, Matías
Año de publicación
2019
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A strategy toward the integration of highly functional microporous materials, such as metal-organic frameworks (MOFs), in composites via biochemical recognition interactions is presented. Postsynthetic modification of zeolitic-imidazolate framework-8 MOF nanocrystals with a maltose-exposing biocompatible surfactant (the socalled “Glyco-MOFs”) was performed to confer affinity toward lectin protein concanavalin A. The addition of small amounts of concanavalin A to the colloidal Glyco-MOF dispersion triggers the aggregation of these units into self-limited size supramolecular architectures directed by specific sugar−lectin binding interactions.
Facultad de Ciencias Exactas
Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas
Materia
Ciencias Exactas
Química
crystals
carbohydrates
metal organic frameworks
suspensions
nanocrystals
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/108006

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oai_identifier_str oai:sedici.unlp.edu.ar:10915/108006
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Lectin-Recognizable MOF Glyconanoparticles: Supramolecular Glycosylation of ZIF-8 Nanocrystals by Sugar-Based SurfactantsGiménez, Rodrigo EstebanPiccinini, EstebanAzzaroni, OmarRafti, MatíasCiencias ExactasQuímicacrystalscarbohydratesmetal organic frameworkssuspensionsnanocrystalsA strategy toward the integration of highly functional microporous materials, such as metal-organic frameworks (MOFs), in composites via biochemical recognition interactions is presented. Postsynthetic modification of zeolitic-imidazolate framework-8 MOF nanocrystals with a maltose-exposing biocompatible surfactant (the socalled “Glyco-MOFs”) was performed to confer affinity toward lectin protein concanavalin A. The addition of small amounts of concanavalin A to the colloidal Glyco-MOF dispersion triggers the aggregation of these units into self-limited size supramolecular architectures directed by specific sugar−lectin binding interactions.Facultad de Ciencias ExactasInstituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf842-848http://sedici.unlp.edu.ar/handle/10915/108006enginfo:eu-repo/semantics/altIdentifier/url/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6648402&blobtype=pdfinfo:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/acsomega.8b03092info:eu-repo/semantics/altIdentifier/issn/2470-1343info:eu-repo/semantics/altIdentifier/pmid/31459362info:eu-repo/semantics/altIdentifier/doi/10.1021/acsomega.8b03092info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:23:52Zoai:sedici.unlp.edu.ar:10915/108006Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:23:52.815SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Lectin-Recognizable MOF Glyconanoparticles: Supramolecular Glycosylation of ZIF-8 Nanocrystals by Sugar-Based Surfactants
title Lectin-Recognizable MOF Glyconanoparticles: Supramolecular Glycosylation of ZIF-8 Nanocrystals by Sugar-Based Surfactants
spellingShingle Lectin-Recognizable MOF Glyconanoparticles: Supramolecular Glycosylation of ZIF-8 Nanocrystals by Sugar-Based Surfactants
Giménez, Rodrigo Esteban
Ciencias Exactas
Química
crystals
carbohydrates
metal organic frameworks
suspensions
nanocrystals
title_short Lectin-Recognizable MOF Glyconanoparticles: Supramolecular Glycosylation of ZIF-8 Nanocrystals by Sugar-Based Surfactants
title_full Lectin-Recognizable MOF Glyconanoparticles: Supramolecular Glycosylation of ZIF-8 Nanocrystals by Sugar-Based Surfactants
title_fullStr Lectin-Recognizable MOF Glyconanoparticles: Supramolecular Glycosylation of ZIF-8 Nanocrystals by Sugar-Based Surfactants
title_full_unstemmed Lectin-Recognizable MOF Glyconanoparticles: Supramolecular Glycosylation of ZIF-8 Nanocrystals by Sugar-Based Surfactants
title_sort Lectin-Recognizable MOF Glyconanoparticles: Supramolecular Glycosylation of ZIF-8 Nanocrystals by Sugar-Based Surfactants
dc.creator.none.fl_str_mv Giménez, Rodrigo Esteban
Piccinini, Esteban
Azzaroni, Omar
Rafti, Matías
author Giménez, Rodrigo Esteban
author_facet Giménez, Rodrigo Esteban
Piccinini, Esteban
Azzaroni, Omar
Rafti, Matías
author_role author
author2 Piccinini, Esteban
Azzaroni, Omar
Rafti, Matías
author2_role author
author
author
dc.subject.none.fl_str_mv Ciencias Exactas
Química
crystals
carbohydrates
metal organic frameworks
suspensions
nanocrystals
topic Ciencias Exactas
Química
crystals
carbohydrates
metal organic frameworks
suspensions
nanocrystals
dc.description.none.fl_txt_mv A strategy toward the integration of highly functional microporous materials, such as metal-organic frameworks (MOFs), in composites via biochemical recognition interactions is presented. Postsynthetic modification of zeolitic-imidazolate framework-8 MOF nanocrystals with a maltose-exposing biocompatible surfactant (the socalled “Glyco-MOFs”) was performed to confer affinity toward lectin protein concanavalin A. The addition of small amounts of concanavalin A to the colloidal Glyco-MOF dispersion triggers the aggregation of these units into self-limited size supramolecular architectures directed by specific sugar−lectin binding interactions.
Facultad de Ciencias Exactas
Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas
description A strategy toward the integration of highly functional microporous materials, such as metal-organic frameworks (MOFs), in composites via biochemical recognition interactions is presented. Postsynthetic modification of zeolitic-imidazolate framework-8 MOF nanocrystals with a maltose-exposing biocompatible surfactant (the socalled “Glyco-MOFs”) was performed to confer affinity toward lectin protein concanavalin A. The addition of small amounts of concanavalin A to the colloidal Glyco-MOF dispersion triggers the aggregation of these units into self-limited size supramolecular architectures directed by specific sugar−lectin binding interactions.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/108006
url http://sedici.unlp.edu.ar/handle/10915/108006
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6648402&blobtype=pdf
info:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/acsomega.8b03092
info:eu-repo/semantics/altIdentifier/issn/2470-1343
info:eu-repo/semantics/altIdentifier/pmid/31459362
info:eu-repo/semantics/altIdentifier/doi/10.1021/acsomega.8b03092
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
842-848
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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