Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine
- Autores
- García, Carlos; Lagos, Marcelo; Truan, Dominique; Lattes, Karinna; Véjar, Omar; Chamorro, Beatriz; Iglesias, Verónica; Andrinolo, Darío; Lagos, Néstor
- Año de publicación
- 2005
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- This study reports the data recorded from four patients intoxicated with shellfish during the summer 2002, after consuming ribbed mussels (Aulacomya ater) with paralytic shellfish toxin contents of 8,066 ± 61.37 μg/ 100 gr of tissue. Data associated with clinical variables and paralytic shellfish toxins analysis in plasma and urine of the intoxicated patients are shown. For this purpose, the evolution of respiratory frequency, arterial blood pressure and heart rate of the poisoned patients were followed and recorded. The clinical treatment to reach a clinically stable condition and return to normal physiological parameters was a combination of hydration with saline solution supplemented with Dobutamine (vasoactive drug), Furosemide (diuretic) and Ranitidine (inhibitor of acid secretion). The physiological condition of patients began to improve after four hours of clinical treatment, and a stable condition was reached between 12 to 24 hours. The HPLC-FLD analysis showed only the GTX3/GTX2 epimers in the blood and urine samples. Also, these epimers were the only paralytic shellfish toxins found in the shellfish extract sample.
Facultad de Ciencias Exactas - Materia
-
Ciencias Exactas
paralytic shellfish poisoning
PSP human intoxication
Chilean fjords - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- http://creativecommons.org/licenses/by/4.0/
- Repositorio
.jpg)
- Institución
- Universidad Nacional de La Plata
- OAI Identificador
- oai:sedici.unlp.edu.ar:10915/108926
Ver los metadatos del registro completo
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Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urineGarcía, CarlosLagos, MarceloTruan, DominiqueLattes, KarinnaVéjar, OmarChamorro, BeatrizIglesias, VerónicaAndrinolo, DaríoLagos, NéstorCiencias Exactasparalytic shellfish poisoningPSP human intoxicationChilean fjordsThis study reports the data recorded from four patients intoxicated with shellfish during the summer 2002, after consuming ribbed mussels (Aulacomya ater) with paralytic shellfish toxin contents of 8,066 ± 61.37 μg/ 100 gr of tissue. Data associated with clinical variables and paralytic shellfish toxins analysis in plasma and urine of the intoxicated patients are shown. For this purpose, the evolution of respiratory frequency, arterial blood pressure and heart rate of the poisoned patients were followed and recorded. The clinical treatment to reach a clinically stable condition and return to normal physiological parameters was a combination of hydration with saline solution supplemented with Dobutamine (vasoactive drug), Furosemide (diuretic) and Ranitidine (inhibitor of acid secretion). The physiological condition of patients began to improve after four hours of clinical treatment, and a stable condition was reached between 12 to 24 hours. The HPLC-FLD analysis showed only the GTX3/GTX2 epimers in the blood and urine samples. Also, these epimers were the only paralytic shellfish toxins found in the shellfish extract sample.Facultad de Ciencias Exactas2005info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf197-205http://sedici.unlp.edu.ar/handle/10915/108926enginfo:eu-repo/semantics/altIdentifier/issn/0716-9760info:eu-repo/semantics/altIdentifier/doi/10.4067/S0716-97602005000200009info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-12-23T11:26:51Zoai:sedici.unlp.edu.ar:10915/108926Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-12-23 11:26:51.593SEDICI (UNLP) - Universidad Nacional de La Platafalse |
| dc.title.none.fl_str_mv |
Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine |
| title |
Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine |
| spellingShingle |
Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine García, Carlos Ciencias Exactas paralytic shellfish poisoning PSP human intoxication Chilean fjords |
| title_short |
Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine |
| title_full |
Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine |
| title_fullStr |
Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine |
| title_full_unstemmed |
Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine |
| title_sort |
Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine |
| dc.creator.none.fl_str_mv |
García, Carlos Lagos, Marcelo Truan, Dominique Lattes, Karinna Véjar, Omar Chamorro, Beatriz Iglesias, Verónica Andrinolo, Darío Lagos, Néstor |
| author |
García, Carlos |
| author_facet |
García, Carlos Lagos, Marcelo Truan, Dominique Lattes, Karinna Véjar, Omar Chamorro, Beatriz Iglesias, Verónica Andrinolo, Darío Lagos, Néstor |
| author_role |
author |
| author2 |
Lagos, Marcelo Truan, Dominique Lattes, Karinna Véjar, Omar Chamorro, Beatriz Iglesias, Verónica Andrinolo, Darío Lagos, Néstor |
| author2_role |
author author author author author author author author |
| dc.subject.none.fl_str_mv |
Ciencias Exactas paralytic shellfish poisoning PSP human intoxication Chilean fjords |
| topic |
Ciencias Exactas paralytic shellfish poisoning PSP human intoxication Chilean fjords |
| dc.description.none.fl_txt_mv |
This study reports the data recorded from four patients intoxicated with shellfish during the summer 2002, after consuming ribbed mussels (Aulacomya ater) with paralytic shellfish toxin contents of 8,066 ± 61.37 μg/ 100 gr of tissue. Data associated with clinical variables and paralytic shellfish toxins analysis in plasma and urine of the intoxicated patients are shown. For this purpose, the evolution of respiratory frequency, arterial blood pressure and heart rate of the poisoned patients were followed and recorded. The clinical treatment to reach a clinically stable condition and return to normal physiological parameters was a combination of hydration with saline solution supplemented with Dobutamine (vasoactive drug), Furosemide (diuretic) and Ranitidine (inhibitor of acid secretion). The physiological condition of patients began to improve after four hours of clinical treatment, and a stable condition was reached between 12 to 24 hours. The HPLC-FLD analysis showed only the GTX3/GTX2 epimers in the blood and urine samples. Also, these epimers were the only paralytic shellfish toxins found in the shellfish extract sample. Facultad de Ciencias Exactas |
| description |
This study reports the data recorded from four patients intoxicated with shellfish during the summer 2002, after consuming ribbed mussels (Aulacomya ater) with paralytic shellfish toxin contents of 8,066 ± 61.37 μg/ 100 gr of tissue. Data associated with clinical variables and paralytic shellfish toxins analysis in plasma and urine of the intoxicated patients are shown. For this purpose, the evolution of respiratory frequency, arterial blood pressure and heart rate of the poisoned patients were followed and recorded. The clinical treatment to reach a clinically stable condition and return to normal physiological parameters was a combination of hydration with saline solution supplemented with Dobutamine (vasoactive drug), Furosemide (diuretic) and Ranitidine (inhibitor of acid secretion). The physiological condition of patients began to improve after four hours of clinical treatment, and a stable condition was reached between 12 to 24 hours. The HPLC-FLD analysis showed only the GTX3/GTX2 epimers in the blood and urine samples. Also, these epimers were the only paralytic shellfish toxins found in the shellfish extract sample. |
| publishDate |
2005 |
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2005 |
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eng |
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