Genotoxic Effects Induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae)

Autores: Gasulla, Javier; Picco, Sebastián Julio; Carriquiriborde, Pedro; Dulout, Fernando Noel; Ronco, Alicia Estela; De Luca, Julio César
Año de publicación: 2016
Idioma: inglés
Tipo de recurso: artículo
Estado: versión publicada
Descripción: Genotoxic effects of Cd(+2), Cr(+6), and Cu(+2) on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr(+6) and Cu(+2), and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd(+2) by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd(+2) and Cr(+6) and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ.
Consejo Nacional de Investigaciones Científicas y Técnicas
Centro de Investigaciones del Medioambiente
Instituto de Genética Veterinaria
Materia: Ciencias Naturales
Heavy metals
Genotoxicity
Pejerrey
Río de la Plata Basin
Nivel de accesibilidad: acceso abierto
Condiciones de uso: http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
Institución: Universidad Nacional de La Plata
OAI Identificador: oai:sedici.unlp.edu.ar:10915/131677

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spelling	Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)Gasulla, JavierPicco, Sebastián JulioCarriquiriborde, PedroDulout, Fernando NoelRonco, Alicia EstelaDe Luca, Julio CésarCiencias NaturalesHeavy metalsGenotoxicityPejerreyRío de la Plata BasinGenotoxic effects of Cd(+2), Cr(+6), and Cu(+2) on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr(+6) and Cu(+2), and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd(+2) by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd(+2) and Cr(+6) and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ.Consejo Nacional de Investigaciones Científicas y TécnicasCentro de Investigaciones del MedioambienteInstituto de Genética Veterinaria2016-03-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf591-595http://sedici.unlp.edu.ar/handle/10915/131677enginfo:eu-repo/semantics/altIdentifier/issn/1432-0800info:eu-repo/semantics/altIdentifier/issn/0007-4861info:eu-repo/semantics/altIdentifier/doi/10.1007/s00128-016-1774-yinfo:eu-repo/semantics/altIdentifier/pmid/27003804info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:31:52Zoai:sedici.unlp.edu.ar:10915/131677Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:31:52.474SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv	Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)
title	Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)
spellingShingle	Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae) Gasulla, Javier Ciencias Naturales Heavy metals Genotoxicity Pejerrey Río de la Plata Basin
title_short	Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)
title_full	Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)
title_fullStr	Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)
title_full_unstemmed	Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)
title_sort	Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)
dc.creator.none.fl_str_mv	Gasulla, Javier Picco, Sebastián Julio Carriquiriborde, Pedro Dulout, Fernando Noel Ronco, Alicia Estela De Luca, Julio César
author	Gasulla, Javier
author_facet	Gasulla, Javier Picco, Sebastián Julio Carriquiriborde, Pedro Dulout, Fernando Noel Ronco, Alicia Estela De Luca, Julio César
author_role	author
author2	Picco, Sebastián Julio Carriquiriborde, Pedro Dulout, Fernando Noel Ronco, Alicia Estela De Luca, Julio César
author2_role	author author author author author
dc.subject.none.fl_str_mv	Ciencias Naturales Heavy metals Genotoxicity Pejerrey Río de la Plata Basin
topic	Ciencias Naturales Heavy metals Genotoxicity Pejerrey Río de la Plata Basin
dc.description.none.fl_txt_mv	Genotoxic effects of Cd(+2), Cr(+6), and Cu(+2) on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr(+6) and Cu(+2), and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd(+2) by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd(+2) and Cr(+6) and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ. Consejo Nacional de Investigaciones Científicas y Técnicas Centro de Investigaciones del Medioambiente Instituto de Genética Veterinaria
description	Genotoxic effects of Cd(+2), Cr(+6), and Cu(+2) on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr(+6) and Cu(+2), and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd(+2) by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd(+2) and Cr(+6) and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ.
publishDate	2016
dc.date.none.fl_str_mv	2016-03-22
dc.type.none.fl_str_mv	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Articulo http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo
format	article
status_str	publishedVersion
dc.identifier.none.fl_str_mv	http://sedici.unlp.edu.ar/handle/10915/131677
url	http://sedici.unlp.edu.ar/handle/10915/131677
dc.language.none.fl_str_mv	eng
language	eng
dc.relation.none.fl_str_mv	info:eu-repo/semantics/altIdentifier/issn/1432-0800 info:eu-repo/semantics/altIdentifier/issn/0007-4861 info:eu-repo/semantics/altIdentifier/doi/10.1007/s00128-016-1774-y info:eu-repo/semantics/altIdentifier/pmid/27003804
dc.rights.none.fl_str_mv	info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv	openAccess
rights_invalid_str_mv	http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv	application/pdf 591-595
dc.source.none.fl_str_mv	reponame:SEDICI (UNLP) instname:Universidad Nacional de La Plata instacron:UNLP
reponame_str	SEDICI (UNLP)
collection	SEDICI (UNLP)
instname_str	Universidad Nacional de La Plata
instacron_str	UNLP
institution	UNLP
repository.name.fl_str_mv	SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv	alira@sedici.unlp.edu.ar
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Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)

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