Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)
- Autores
- Gasulla, Javier; Picco, Sebastián Julio; Carriquiriborde, Pedro; Dulout, Fernando Noel; Ronco, Alicia Estela; De Luca, Julio César
- Año de publicación
- 2016
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Genotoxic effects of Cd(+2), Cr(+6), and Cu(+2) on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr(+6) and Cu(+2), and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd(+2) by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd(+2) and Cr(+6) and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ.
Consejo Nacional de Investigaciones Científicas y Técnicas
Centro de Investigaciones del Medioambiente
Instituto de Genética Veterinaria - Materia
-
Ciencias Naturales
Heavy metals
Genotoxicity
Pejerrey
Río de la Plata Basin - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- http://creativecommons.org/licenses/by-nc-sa/4.0/
- Repositorio
- Institución
- Universidad Nacional de La Plata
- OAI Identificador
- oai:sedici.unlp.edu.ar:10915/131677
Ver los metadatos del registro completo
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Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)Gasulla, JavierPicco, Sebastián JulioCarriquiriborde, PedroDulout, Fernando NoelRonco, Alicia EstelaDe Luca, Julio CésarCiencias NaturalesHeavy metalsGenotoxicityPejerreyRío de la Plata BasinGenotoxic effects of Cd(+2), Cr(+6), and Cu(+2) on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr(+6) and Cu(+2), and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd(+2) by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd(+2) and Cr(+6) and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ.Consejo Nacional de Investigaciones Científicas y TécnicasCentro de Investigaciones del MedioambienteInstituto de Genética Veterinaria2016-03-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf591-595http://sedici.unlp.edu.ar/handle/10915/131677enginfo:eu-repo/semantics/altIdentifier/issn/1432-0800info:eu-repo/semantics/altIdentifier/issn/0007-4861info:eu-repo/semantics/altIdentifier/doi/10.1007/s00128-016-1774-yinfo:eu-repo/semantics/altIdentifier/pmid/27003804info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-03T11:03:58Zoai:sedici.unlp.edu.ar:10915/131677Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-03 11:03:58.53SEDICI (UNLP) - Universidad Nacional de La Platafalse |
dc.title.none.fl_str_mv |
Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae) |
title |
Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae) |
spellingShingle |
Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae) Gasulla, Javier Ciencias Naturales Heavy metals Genotoxicity Pejerrey Río de la Plata Basin |
title_short |
Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae) |
title_full |
Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae) |
title_fullStr |
Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae) |
title_full_unstemmed |
Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae) |
title_sort |
Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae) |
dc.creator.none.fl_str_mv |
Gasulla, Javier Picco, Sebastián Julio Carriquiriborde, Pedro Dulout, Fernando Noel Ronco, Alicia Estela De Luca, Julio César |
author |
Gasulla, Javier |
author_facet |
Gasulla, Javier Picco, Sebastián Julio Carriquiriborde, Pedro Dulout, Fernando Noel Ronco, Alicia Estela De Luca, Julio César |
author_role |
author |
author2 |
Picco, Sebastián Julio Carriquiriborde, Pedro Dulout, Fernando Noel Ronco, Alicia Estela De Luca, Julio César |
author2_role |
author author author author author |
dc.subject.none.fl_str_mv |
Ciencias Naturales Heavy metals Genotoxicity Pejerrey Río de la Plata Basin |
topic |
Ciencias Naturales Heavy metals Genotoxicity Pejerrey Río de la Plata Basin |
dc.description.none.fl_txt_mv |
Genotoxic effects of Cd(+2), Cr(+6), and Cu(+2) on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr(+6) and Cu(+2), and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd(+2) by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd(+2) and Cr(+6) and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ. Consejo Nacional de Investigaciones Científicas y Técnicas Centro de Investigaciones del Medioambiente Instituto de Genética Veterinaria |
description |
Genotoxic effects of Cd(+2), Cr(+6), and Cu(+2) on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr(+6) and Cu(+2), and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd(+2) by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd(+2) and Cr(+6) and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-03-22 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Articulo http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://sedici.unlp.edu.ar/handle/10915/131677 |
url |
http://sedici.unlp.edu.ar/handle/10915/131677 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/issn/1432-0800 info:eu-repo/semantics/altIdentifier/issn/0007-4861 info:eu-repo/semantics/altIdentifier/doi/10.1007/s00128-016-1774-y info:eu-repo/semantics/altIdentifier/pmid/27003804 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) |
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application/pdf 591-595 |
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SEDICI (UNLP) - Universidad Nacional de La Plata |
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