Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)

Autores
Gasulla, Javier; Picco, Sebastián Julio; Carriquiriborde, Pedro; Dulout, Fernando Noel; Ronco, Alicia Estela; De Luca, Julio César
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Genotoxic effects of Cd(+2), Cr(+6), and Cu(+2) on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr(+6) and Cu(+2), and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd(+2) by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd(+2) and Cr(+6) and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ.
Consejo Nacional de Investigaciones Científicas y Técnicas
Centro de Investigaciones del Medioambiente
Instituto de Genética Veterinaria
Materia
Ciencias Naturales
Heavy metals
Genotoxicity
Pejerrey
Río de la Plata Basin
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/131677

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network_name_str SEDICI (UNLP)
spelling Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)Gasulla, JavierPicco, Sebastián JulioCarriquiriborde, PedroDulout, Fernando NoelRonco, Alicia EstelaDe Luca, Julio CésarCiencias NaturalesHeavy metalsGenotoxicityPejerreyRío de la Plata BasinGenotoxic effects of Cd(+2), Cr(+6), and Cu(+2) on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr(+6) and Cu(+2), and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd(+2) by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd(+2) and Cr(+6) and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ.Consejo Nacional de Investigaciones Científicas y TécnicasCentro de Investigaciones del MedioambienteInstituto de Genética Veterinaria2016-03-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf591-595http://sedici.unlp.edu.ar/handle/10915/131677enginfo:eu-repo/semantics/altIdentifier/issn/1432-0800info:eu-repo/semantics/altIdentifier/issn/0007-4861info:eu-repo/semantics/altIdentifier/doi/10.1007/s00128-016-1774-yinfo:eu-repo/semantics/altIdentifier/pmid/27003804info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-03T11:03:58Zoai:sedici.unlp.edu.ar:10915/131677Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-03 11:03:58.53SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)
title Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)
spellingShingle Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)
Gasulla, Javier
Ciencias Naturales
Heavy metals
Genotoxicity
Pejerrey
Río de la Plata Basin
title_short Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)
title_full Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)
title_fullStr Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)
title_full_unstemmed Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)
title_sort Genotoxic Effects Induced by Cd<SUP>+2</SUP>, Cr<SUP>+6</SUP>, Cu<SUP>+2</SUP> in the Gill and Liver of <i>Odontesthes bonariensis</i> (Piscies, Atherinopsidae)
dc.creator.none.fl_str_mv Gasulla, Javier
Picco, Sebastián Julio
Carriquiriborde, Pedro
Dulout, Fernando Noel
Ronco, Alicia Estela
De Luca, Julio César
author Gasulla, Javier
author_facet Gasulla, Javier
Picco, Sebastián Julio
Carriquiriborde, Pedro
Dulout, Fernando Noel
Ronco, Alicia Estela
De Luca, Julio César
author_role author
author2 Picco, Sebastián Julio
Carriquiriborde, Pedro
Dulout, Fernando Noel
Ronco, Alicia Estela
De Luca, Julio César
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Ciencias Naturales
Heavy metals
Genotoxicity
Pejerrey
Río de la Plata Basin
topic Ciencias Naturales
Heavy metals
Genotoxicity
Pejerrey
Río de la Plata Basin
dc.description.none.fl_txt_mv Genotoxic effects of Cd(+2), Cr(+6), and Cu(+2) on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr(+6) and Cu(+2), and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd(+2) by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd(+2) and Cr(+6) and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ.
Consejo Nacional de Investigaciones Científicas y Técnicas
Centro de Investigaciones del Medioambiente
Instituto de Genética Veterinaria
description Genotoxic effects of Cd(+2), Cr(+6), and Cu(+2) on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr(+6) and Cu(+2), and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd(+2) by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd(+2) and Cr(+6) and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ.
publishDate 2016
dc.date.none.fl_str_mv 2016-03-22
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/131677
url http://sedici.unlp.edu.ar/handle/10915/131677
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/1432-0800
info:eu-repo/semantics/altIdentifier/issn/0007-4861
info:eu-repo/semantics/altIdentifier/doi/10.1007/s00128-016-1774-y
info:eu-repo/semantics/altIdentifier/pmid/27003804
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
591-595
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
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repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
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