Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae)

Autores
Gasulla, Javier; Carriquiriborde, Pedro; Picco, Sebastian Julio; Ronco, Alicia Estela; de Luca, Julio Cesar
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión aceptada
Descripción
Genotoxic effects of Cd?2, Cr?6, and Cu?2 on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr?6 and Cu?2, and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd?2 by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd?2 and Cr?6 and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ.
Inst. de Microbiología y Zoología Agrícola IMyZA
Fil: Gasulla, Javier. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Microbiología y Zoología Agrícola; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular; Argentina
Fil: Picco, Sebastian Julio. Consejo Nacional de Invest.cientif.y Tecnicas. Centro Cientifico Tecnol.conicet - la Plata. Instituto de Genetica Veterinaria Ing Fernando Noel Dulout; Universidad Nacional de la Plata. Facultad de Cs.veterinarias. Departamento de Cs.basicas. Laboratorio de Nutricion Mineral y Fisiologia Reproductiva; Argentina
Fil: Carriquiriborde, Pedro. Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Departamento de Química. Centro de Investigaciones del Medio Ambiente; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Cientifico Tecnológico La Plata; Argentina
Fil: Ronco, Alicia Estela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmosfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmosfera; Argentina
Fil: de Luca, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Instituto de Genética Veterinaria "Ingeniero Fernando Noel Dulout"; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina
Fuente
Bulletin of environmental contamination and toxicology 96 (5) : 591–595. (May 2016)
Materia
Genotoxicity
Fishes
Genotoxicidad
Odontesthes bonariensis
Peces
Nivel de accesibilidad
acceso restringido
Condiciones de uso
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/1041
Acceder
id INTADig_a6ea15b0ea9ed5c5e86d2837f2de0fef
oai_identifier_str oai:localhost:20.500.12123/1041
network_acronym_str INTADig
repository_id_str l
network_name_str INTA Digital (INTA)
spelling Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae)Gasulla, JavierCarriquiriborde, PedroPicco, Sebastian JulioRonco, Alicia Estelade Luca, Julio CesarGenotoxicityFishesGenotoxicidadOdontesthes bonariensisPecesGenotoxic effects of Cd?2, Cr?6, and Cu?2 on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr?6 and Cu?2, and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd?2 by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd?2 and Cr?6 and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ.Inst. de Microbiología y Zoología Agrícola IMyZAFil: Gasulla, Javier. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Microbiología y Zoología Agrícola; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular; ArgentinaFil: Picco, Sebastian Julio. Consejo Nacional de Invest.cientif.y Tecnicas. Centro Cientifico Tecnol.conicet - la Plata. Instituto de Genetica Veterinaria Ing Fernando Noel Dulout; Universidad Nacional de la Plata. Facultad de Cs.veterinarias. Departamento de Cs.basicas. Laboratorio de Nutricion Mineral y Fisiologia Reproductiva; ArgentinaFil: Carriquiriborde, Pedro. Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Departamento de Química. Centro de Investigaciones del Medio Ambiente; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Cientifico Tecnológico La Plata; ArgentinaFil: Ronco, Alicia Estela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmosfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmosfera; ArgentinaFil: de Luca, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Instituto de Genética Veterinaria "Ingeniero Fernando Noel Dulout"; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina2017-08-25T12:51:27Z2017-08-25T12:51:27Z2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/1041https://link.springer.com/article/10.1007%2Fs00128-016-1774-y0007-4861 (Print)1432-0800 (Online)https://doi.org/10.1007/s00128-016-1774-yBulletin of environmental contamination and toxicology 96 (5) : 591–595. (May 2016)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/restrictedAccess2025-09-04T09:46:58Zoai:localhost:20.500.12123/1041instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-04 09:46:58.491INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae)
title Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae)
spellingShingle Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae)
Gasulla, Javier
Genotoxicity
Fishes
Genotoxicidad
Odontesthes bonariensis
Peces
title_short Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae)
title_full Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae)
title_fullStr Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae)
title_full_unstemmed Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae)
title_sort Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae)
dc.creator.none.fl_str_mv Gasulla, Javier
Carriquiriborde, Pedro
Picco, Sebastian Julio
Ronco, Alicia Estela
de Luca, Julio Cesar
author Gasulla, Javier
author_facet Gasulla, Javier
Carriquiriborde, Pedro
Picco, Sebastian Julio
Ronco, Alicia Estela
de Luca, Julio Cesar
author_role author
author2 Carriquiriborde, Pedro
Picco, Sebastian Julio
Ronco, Alicia Estela
de Luca, Julio Cesar
author2_role author
author
author
author
dc.subject.none.fl_str_mv Genotoxicity
Fishes
Genotoxicidad
Odontesthes bonariensis
Peces
topic Genotoxicity
Fishes
Genotoxicidad
Odontesthes bonariensis
Peces
dc.description.none.fl_txt_mv Genotoxic effects of Cd?2, Cr?6, and Cu?2 on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr?6 and Cu?2, and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd?2 by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd?2 and Cr?6 and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ.
Inst. de Microbiología y Zoología Agrícola IMyZA
Fil: Gasulla, Javier. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Microbiología y Zoología Agrícola; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular; Argentina
Fil: Picco, Sebastian Julio. Consejo Nacional de Invest.cientif.y Tecnicas. Centro Cientifico Tecnol.conicet - la Plata. Instituto de Genetica Veterinaria Ing Fernando Noel Dulout; Universidad Nacional de la Plata. Facultad de Cs.veterinarias. Departamento de Cs.basicas. Laboratorio de Nutricion Mineral y Fisiologia Reproductiva; Argentina
Fil: Carriquiriborde, Pedro. Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Departamento de Química. Centro de Investigaciones del Medio Ambiente; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Cientifico Tecnológico La Plata; Argentina
Fil: Ronco, Alicia Estela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmosfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmosfera; Argentina
Fil: de Luca, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Instituto de Genética Veterinaria "Ingeniero Fernando Noel Dulout"; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina
description Genotoxic effects of Cd?2, Cr?6, and Cu?2 on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr?6 and Cu?2, and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd?2 by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd?2 and Cr?6 and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ.
publishDate 2016
dc.date.none.fl_str_mv 2016
2017-08-25T12:51:27Z
2017-08-25T12:51:27Z
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/1041
https://link.springer.com/article/10.1007%2Fs00128-016-1774-y
0007-4861 (Print)
1432-0800 (Online)
https://doi.org/10.1007/s00128-016-1774-y
url http://hdl.handle.net/20.500.12123/1041
https://link.springer.com/article/10.1007%2Fs00128-016-1774-y
https://doi.org/10.1007/s00128-016-1774-y
identifier_str_mv 0007-4861 (Print)
1432-0800 (Online)
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
eu_rights_str_mv restrictedAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Bulletin of environmental contamination and toxicology 96 (5) : 591–595. (May 2016)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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score 12.623145

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