Toward personalization of asthma treatment according to trigger factors

Autores
Docena, Guillermo Horacio
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Asthma is a severe and chronic disabling disease affecting more than 300 million people worldwide. Although in the past few drugs for the treatment of asthma were available, new treatment options are currently emerging, which appear to be highly effective in certain subgroups of patients. Accordingly, there is a need for biomarkers that allow selection of patients for refined and personalized treatment strategies. Recently, serological chip tests based on microarrayed allergen molecules and peptides derived from the most common rhinovirus strains have been developed, which may discriminate 2 of the most common forms of asthma, that is, allergen- and virus-triggered asthma. In this perspective, we argue that classification of patients with asthma according to these common trigger factors may open new possibilities for personalized management of asthma.
La lista completa de autores que integran el documento puede consultarse en el archivo.
Facultad de Ciencias Exactas
Materia
Ciencias Médicas
Bioquímica
Asthma
Allergy
Wheeze
Rhinovirus
Allergen
Microarray
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-nd/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/142824
Acceder
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repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Toward personalization of asthma treatment according to trigger factorsDocena, Guillermo HoracioCiencias MédicasBioquímicaAsthmaAllergyWheezeRhinovirusAllergenMicroarrayAsthma is a severe and chronic disabling disease affecting more than 300 million people worldwide. Although in the past few drugs for the treatment of asthma were available, new treatment options are currently emerging, which appear to be highly effective in certain subgroups of patients. Accordingly, there is a need for biomarkers that allow selection of patients for refined and personalized treatment strategies. Recently, serological chip tests based on microarrayed allergen molecules and peptides derived from the most common rhinovirus strains have been developed, which may discriminate 2 of the most common forms of asthma, that is, allergen- and virus-triggered asthma. In this perspective, we argue that classification of patients with asthma according to these common trigger factors may open new possibilities for personalized management of asthma.La lista completa de autores que integran el documento puede consultarse en el archivo.Facultad de Ciencias Exactas2020-02-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf1529-1534http://sedici.unlp.edu.ar/handle/10915/142824enginfo:eu-repo/semantics/altIdentifier/issn/1097-6825info:eu-repo/semantics/altIdentifier/issn/0091-6749info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jaci.2020.02.001info:eu-repo/semantics/altIdentifier/pmid/32081759info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/4.0/Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-10-15T11:24:24Zoai:sedici.unlp.edu.ar:10915/142824Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-10-15 11:24:25.129SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Toward personalization of asthma treatment according to trigger factors
title Toward personalization of asthma treatment according to trigger factors
spellingShingle Toward personalization of asthma treatment according to trigger factors
Docena, Guillermo Horacio
Ciencias Médicas
Bioquímica
Asthma
Allergy
Wheeze
Rhinovirus
Allergen
Microarray
title_short Toward personalization of asthma treatment according to trigger factors
title_full Toward personalization of asthma treatment according to trigger factors
title_fullStr Toward personalization of asthma treatment according to trigger factors
title_full_unstemmed Toward personalization of asthma treatment according to trigger factors
title_sort Toward personalization of asthma treatment according to trigger factors
dc.creator.none.fl_str_mv Docena, Guillermo Horacio
author Docena, Guillermo Horacio
author_facet Docena, Guillermo Horacio
author_role author
dc.subject.none.fl_str_mv Ciencias Médicas
Bioquímica
Asthma
Allergy
Wheeze
Rhinovirus
Allergen
Microarray
topic Ciencias Médicas
Bioquímica
Asthma
Allergy
Wheeze
Rhinovirus
Allergen
Microarray
dc.description.none.fl_txt_mv Asthma is a severe and chronic disabling disease affecting more than 300 million people worldwide. Although in the past few drugs for the treatment of asthma were available, new treatment options are currently emerging, which appear to be highly effective in certain subgroups of patients. Accordingly, there is a need for biomarkers that allow selection of patients for refined and personalized treatment strategies. Recently, serological chip tests based on microarrayed allergen molecules and peptides derived from the most common rhinovirus strains have been developed, which may discriminate 2 of the most common forms of asthma, that is, allergen- and virus-triggered asthma. In this perspective, we argue that classification of patients with asthma according to these common trigger factors may open new possibilities for personalized management of asthma.
La lista completa de autores que integran el documento puede consultarse en el archivo.
Facultad de Ciencias Exactas
description Asthma is a severe and chronic disabling disease affecting more than 300 million people worldwide. Although in the past few drugs for the treatment of asthma were available, new treatment options are currently emerging, which appear to be highly effective in certain subgroups of patients. Accordingly, there is a need for biomarkers that allow selection of patients for refined and personalized treatment strategies. Recently, serological chip tests based on microarrayed allergen molecules and peptides derived from the most common rhinovirus strains have been developed, which may discriminate 2 of the most common forms of asthma, that is, allergen- and virus-triggered asthma. In this perspective, we argue that classification of patients with asthma according to these common trigger factors may open new possibilities for personalized management of asthma.
publishDate 2020
dc.date.none.fl_str_mv 2020-02-18
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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http://purl.org/coar/resource_type/c_6501
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dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/142824
url http://sedici.unlp.edu.ar/handle/10915/142824
dc.language.none.fl_str_mv eng
language eng
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info:eu-repo/semantics/altIdentifier/issn/0091-6749
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jaci.2020.02.001
info:eu-repo/semantics/altIdentifier/pmid/32081759
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
dc.format.none.fl_str_mv application/pdf
1529-1534
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repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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