Interactions between West Nile Virus and the microbiota of Culex pipiens vectors: a literature review

Autores
Garrigós, Marta; Garrido, Mario; Panisse, Guillermo; Veiga, Jesús; Martínez-de la Puente, Josué
Año de publicación
2023
Idioma
inglés
Tipo de recurso
reseña artículo
Estado
versión publicada
Descripción
The flavivirus West Nile virus (WNV) naturally circulates between mosquitoes and birds, potentially affecting humans and horses. Different species of mosquitoes play a role as vectors of WNV, with those of the Culex pipiens complex being particularly crucial for its circulation. Different biotic and abiotic factors determine the capacity of mosquitoes for pathogen transmission, with the mosquito gut microbiota being recognized as an important one. Here, we review the published studies on the interactions between the microbiota of the Culex pipiens complex and WNV infections in mosquitoes. Most articles published so far studied the interactions between bacteria of the genus Wolbachia and WNV infections, obtaining variable results regarding the directionality of this relationship. In contrast, only a few studies investigate the role of the whole microbiome or other bacterial taxa in WNV infections. These studies suggest that bacteria of the genera Serratia and Enterobacter may enhance WNV development. Thus, due to the relevance of WNV in human and animal health and the important role of mosquitoes of the Cx. pipiens complex in its transmission, more research is needed to unravel the role of mosquito microbiota and those factors affecting this microbiota on pathogen epidemiology. In this respect, we finally propose future lines of research lines on this topic.
Centro de Estudios Parasitológicos y de Vectores
Materia
Biología
flavivirus
insect vectors
mosquito-borne pathogens
mosquito microbiota
vector competence
Wolbachia
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/160004
Acceder
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oai_identifier_str oai:sedici.unlp.edu.ar:10915/160004
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Interactions between West Nile Virus and the microbiota of Culex pipiens vectors: a literature reviewGarrigós, MartaGarrido, MarioPanisse, GuillermoVeiga, JesúsMartínez-de la Puente, JosuéBiologíaflavivirusinsect vectorsmosquito-borne pathogensmosquito microbiotavector competenceWolbachiaThe flavivirus West Nile virus (WNV) naturally circulates between mosquitoes and birds, potentially affecting humans and horses. Different species of mosquitoes play a role as vectors of WNV, with those of the Culex pipiens complex being particularly crucial for its circulation. Different biotic and abiotic factors determine the capacity of mosquitoes for pathogen transmission, with the mosquito gut microbiota being recognized as an important one. Here, we review the published studies on the interactions between the microbiota of the Culex pipiens complex and WNV infections in mosquitoes. Most articles published so far studied the interactions between bacteria of the genus Wolbachia and WNV infections, obtaining variable results regarding the directionality of this relationship. In contrast, only a few studies investigate the role of the whole microbiome or other bacterial taxa in WNV infections. These studies suggest that bacteria of the genera Serratia and Enterobacter may enhance WNV development. Thus, due to the relevance of WNV in human and animal health and the important role of mosquitoes of the Cx. pipiens complex in its transmission, more research is needed to unravel the role of mosquito microbiota and those factors affecting this microbiota on pathogen epidemiology. In this respect, we finally propose future lines of research lines on this topic.Centro de Estudios Parasitológicos y de Vectores2023info:eu-repo/semantics/reviewinfo:eu-repo/semantics/publishedVersionRevisionhttp://purl.org/coar/resource_type/c_dcae04bcinfo:ar-repo/semantics/resenaArticuloapplication/pdfhttp://sedici.unlp.edu.ar/handle/10915/160004enginfo:eu-repo/semantics/altIdentifier/issn/2076-0817info:eu-repo/semantics/altIdentifier/doi/10.3390/pathogens12111287info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-03T11:13:50Zoai:sedici.unlp.edu.ar:10915/160004Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-03 11:13:50.941SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Interactions between West Nile Virus and the microbiota of Culex pipiens vectors: a literature review
title Interactions between West Nile Virus and the microbiota of Culex pipiens vectors: a literature review
spellingShingle Interactions between West Nile Virus and the microbiota of Culex pipiens vectors: a literature review
Garrigós, Marta
Biología
flavivirus
insect vectors
mosquito-borne pathogens
mosquito microbiota
vector competence
Wolbachia
title_short Interactions between West Nile Virus and the microbiota of Culex pipiens vectors: a literature review
title_full Interactions between West Nile Virus and the microbiota of Culex pipiens vectors: a literature review
title_fullStr Interactions between West Nile Virus and the microbiota of Culex pipiens vectors: a literature review
title_full_unstemmed Interactions between West Nile Virus and the microbiota of Culex pipiens vectors: a literature review
title_sort Interactions between West Nile Virus and the microbiota of Culex pipiens vectors: a literature review
dc.creator.none.fl_str_mv Garrigós, Marta
Garrido, Mario
Panisse, Guillermo
Veiga, Jesús
Martínez-de la Puente, Josué
author Garrigós, Marta
author_facet Garrigós, Marta
Garrido, Mario
Panisse, Guillermo
Veiga, Jesús
Martínez-de la Puente, Josué
author_role author
author2 Garrido, Mario
Panisse, Guillermo
Veiga, Jesús
Martínez-de la Puente, Josué
author2_role author
author
author
author
dc.subject.none.fl_str_mv Biología
flavivirus
insect vectors
mosquito-borne pathogens
mosquito microbiota
vector competence
Wolbachia
topic Biología
flavivirus
insect vectors
mosquito-borne pathogens
mosquito microbiota
vector competence
Wolbachia
dc.description.none.fl_txt_mv The flavivirus West Nile virus (WNV) naturally circulates between mosquitoes and birds, potentially affecting humans and horses. Different species of mosquitoes play a role as vectors of WNV, with those of the Culex pipiens complex being particularly crucial for its circulation. Different biotic and abiotic factors determine the capacity of mosquitoes for pathogen transmission, with the mosquito gut microbiota being recognized as an important one. Here, we review the published studies on the interactions between the microbiota of the Culex pipiens complex and WNV infections in mosquitoes. Most articles published so far studied the interactions between bacteria of the genus Wolbachia and WNV infections, obtaining variable results regarding the directionality of this relationship. In contrast, only a few studies investigate the role of the whole microbiome or other bacterial taxa in WNV infections. These studies suggest that bacteria of the genera Serratia and Enterobacter may enhance WNV development. Thus, due to the relevance of WNV in human and animal health and the important role of mosquitoes of the Cx. pipiens complex in its transmission, more research is needed to unravel the role of mosquito microbiota and those factors affecting this microbiota on pathogen epidemiology. In this respect, we finally propose future lines of research lines on this topic.
Centro de Estudios Parasitológicos y de Vectores
description The flavivirus West Nile virus (WNV) naturally circulates between mosquitoes and birds, potentially affecting humans and horses. Different species of mosquitoes play a role as vectors of WNV, with those of the Culex pipiens complex being particularly crucial for its circulation. Different biotic and abiotic factors determine the capacity of mosquitoes for pathogen transmission, with the mosquito gut microbiota being recognized as an important one. Here, we review the published studies on the interactions between the microbiota of the Culex pipiens complex and WNV infections in mosquitoes. Most articles published so far studied the interactions between bacteria of the genus Wolbachia and WNV infections, obtaining variable results regarding the directionality of this relationship. In contrast, only a few studies investigate the role of the whole microbiome or other bacterial taxa in WNV infections. These studies suggest that bacteria of the genera Serratia and Enterobacter may enhance WNV development. Thus, due to the relevance of WNV in human and animal health and the important role of mosquitoes of the Cx. pipiens complex in its transmission, more research is needed to unravel the role of mosquito microbiota and those factors affecting this microbiota on pathogen epidemiology. In this respect, we finally propose future lines of research lines on this topic.
publishDate 2023
dc.date.none.fl_str_mv 2023
dc.type.none.fl_str_mv info:eu-repo/semantics/review
info:eu-repo/semantics/publishedVersion
Revision
http://purl.org/coar/resource_type/c_dcae04bc
info:ar-repo/semantics/resenaArticulo
format review
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/160004
url http://sedici.unlp.edu.ar/handle/10915/160004
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/2076-0817
info:eu-repo/semantics/altIdentifier/doi/10.3390/pathogens12111287
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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