Response to Letter to the Editor “On the targets of fluoxetine”

Autores
Di Rosso, María Emilia; Palumbo, María Laura; Genaro, Ana María
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Fil: Di Rosso, María Emilia. Pontificia Universidad Católica Argentina. Instituto de Investigaciones Biomédicas; Argentina
Fil: Di Rosso, María Emilia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Palumbo, María Laura. Universidad Nacional del Noroestede la Provincia de Buenos Aires. Centro de Investigaciones y Transferencia del Noroeste de la Provincia de Buenos Aires; Argentina
Fil: Palumbo, María Laura. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Genaro, Ana María. Pontificia Universidad Católica Argentina. Instituto de Investigaciones Biomédicas; Argentina
Fil: Genaro, Ana María. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Genaro, Ana María. Universidad de Buenos Aires; Argentina
We read the Letter to the Editor entitled “On the targets of Flu-oxetine” by James M. Brimson and Stephen T. Safrany referred to our review entitled “Immunomodulatory effects of fluoxetine: Anew potential pharmacological action for a classic antidepressantdrug?”.The authors consider that many of the effects described forfluoxetine could be due to the activation of sigma-1 receptorsuggesting that this receptor could be the “Novel receptor” on lym-phocytes proposed in our review. While sigma receptors activationis mainly known for their effect on the nervous system, the presence of this receptor on non-neuronal tissues, including immunesystem has been described.
Fuente
Pharmacological Research. 113, 2016.
Materia
FARMACOLOGIA
ANTIDEPRESIVOS
FLUOXETINA
RECEPTORES DE SEROTONINA
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
Repositorio Institucional (UCA)
Institución
Pontificia Universidad Católica Argentina
OAI Identificador
oai:ucacris:123456789/19332
Acceder
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oai_identifier_str oai:ucacris:123456789/19332
network_acronym_str RIUCA
repository_id_str 2585
network_name_str Repositorio Institucional (UCA)
spelling Response to Letter to the Editor “On the targets of fluoxetine”Di Rosso, María EmiliaPalumbo, María LauraGenaro, Ana MaríaFARMACOLOGIAANTIDEPRESIVOSFLUOXETINARECEPTORES DE SEROTONINAFil: Di Rosso, María Emilia. Pontificia Universidad Católica Argentina. Instituto de Investigaciones Biomédicas; ArgentinaFil: Di Rosso, María Emilia. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Palumbo, María Laura. Universidad Nacional del Noroestede la Provincia de Buenos Aires. Centro de Investigaciones y Transferencia del Noroeste de la Provincia de Buenos Aires; ArgentinaFil: Palumbo, María Laura. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Genaro, Ana María. Pontificia Universidad Católica Argentina. Instituto de Investigaciones Biomédicas; ArgentinaFil: Genaro, Ana María. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Genaro, Ana María. Universidad de Buenos Aires; ArgentinaWe read the Letter to the Editor entitled “On the targets of Flu-oxetine” by James M. Brimson and Stephen T. Safrany referred to our review entitled “Immunomodulatory effects of fluoxetine: Anew potential pharmacological action for a classic antidepressantdrug?”.The authors consider that many of the effects described forfluoxetine could be due to the activation of sigma-1 receptorsuggesting that this receptor could be the “Novel receptor” on lym-phocytes proposed in our review. While sigma receptors activationis mainly known for their effect on the nervous system, the presence of this receptor on non-neuronal tissues, including immunesystem has been described.Elsevier2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://repositorio.uca.edu.ar/handle/123456789/1933210.1016/j.phrs.2016.06.003Pharmacological Research. 113, 2016.reponame:Repositorio Institucional (UCA)instname:Pontificia Universidad Católica Argentinaenginfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/4.0/2025-07-03T11:00:06Zoai:ucacris:123456789/19332instacron:UCAInstitucionalhttps://repositorio.uca.edu.ar/Universidad privadaNo correspondehttps://repositorio.uca.edu.ar/oaiclaudia_fernandez@uca.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:25852025-07-03 11:00:07.251Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentinafalse
dc.title.none.fl_str_mv Response to Letter to the Editor “On the targets of fluoxetine”
title Response to Letter to the Editor “On the targets of fluoxetine”
spellingShingle Response to Letter to the Editor “On the targets of fluoxetine”
Di Rosso, María Emilia
FARMACOLOGIA
ANTIDEPRESIVOS
FLUOXETINA
RECEPTORES DE SEROTONINA
title_short Response to Letter to the Editor “On the targets of fluoxetine”
title_full Response to Letter to the Editor “On the targets of fluoxetine”
title_fullStr Response to Letter to the Editor “On the targets of fluoxetine”
title_full_unstemmed Response to Letter to the Editor “On the targets of fluoxetine”
title_sort Response to Letter to the Editor “On the targets of fluoxetine”
dc.creator.none.fl_str_mv Di Rosso, María Emilia
Palumbo, María Laura
Genaro, Ana María
author Di Rosso, María Emilia
author_facet Di Rosso, María Emilia
Palumbo, María Laura
Genaro, Ana María
author_role author
author2 Palumbo, María Laura
Genaro, Ana María
author2_role author
author
dc.subject.none.fl_str_mv FARMACOLOGIA
ANTIDEPRESIVOS
FLUOXETINA
RECEPTORES DE SEROTONINA
topic FARMACOLOGIA
ANTIDEPRESIVOS
FLUOXETINA
RECEPTORES DE SEROTONINA
dc.description.none.fl_txt_mv Fil: Di Rosso, María Emilia. Pontificia Universidad Católica Argentina. Instituto de Investigaciones Biomédicas; Argentina
Fil: Di Rosso, María Emilia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Palumbo, María Laura. Universidad Nacional del Noroestede la Provincia de Buenos Aires. Centro de Investigaciones y Transferencia del Noroeste de la Provincia de Buenos Aires; Argentina
Fil: Palumbo, María Laura. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Genaro, Ana María. Pontificia Universidad Católica Argentina. Instituto de Investigaciones Biomédicas; Argentina
Fil: Genaro, Ana María. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Genaro, Ana María. Universidad de Buenos Aires; Argentina
We read the Letter to the Editor entitled “On the targets of Flu-oxetine” by James M. Brimson and Stephen T. Safrany referred to our review entitled “Immunomodulatory effects of fluoxetine: Anew potential pharmacological action for a classic antidepressantdrug?”.The authors consider that many of the effects described forfluoxetine could be due to the activation of sigma-1 receptorsuggesting that this receptor could be the “Novel receptor” on lym-phocytes proposed in our review. While sigma receptors activationis mainly known for their effect on the nervous system, the presence of this receptor on non-neuronal tissues, including immunesystem has been described.
description Fil: Di Rosso, María Emilia. Pontificia Universidad Católica Argentina. Instituto de Investigaciones Biomédicas; Argentina
publishDate 2016
dc.date.none.fl_str_mv 2016
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://repositorio.uca.edu.ar/handle/123456789/19332
10.1016/j.phrs.2016.06.003
url https://repositorio.uca.edu.ar/handle/123456789/19332
identifier_str_mv 10.1016/j.phrs.2016.06.003
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0/
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv Pharmacological Research. 113, 2016.
reponame:Repositorio Institucional (UCA)
instname:Pontificia Universidad Católica Argentina
reponame_str Repositorio Institucional (UCA)
collection Repositorio Institucional (UCA)
instname_str Pontificia Universidad Católica Argentina
repository.name.fl_str_mv Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentina
repository.mail.fl_str_mv claudia_fernandez@uca.edu.ar
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score 13.070432

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