Cardiovascular autonomic adaptation to long-term confinement during a 105-day simulated Mars mission

• Autores: Wan, Li; Ogrinz, Barbara; Vigo, Daniel Eduardo; Bersenev, Evgeny; Tuerlinckx, Francis; Van den Bergh, Omer; Aubert, André E.
• Año de publicación: 2011
• Idioma: inglés
• Tipo de recurso: artículo
• Fuente: Aviation, space, and environmental medicine. 2011, 82 (6)
• Materia: SISTEMA NERVIOSO AUTONOMO; PRESION SANGUINEA; CONFINAMIENTO CONTROLADO; SISTEMA CARDIOVASCULAR
• Institución: Pontificia Universidad Católica Argentina

Fil: Wan, Li. Universidad de Leuven. Departamento de Fisiología; Bélgica
Fil: Ogrinz, Barbara. Universidad de Leuven. Departamento de Fisiología; Bélgica
Fil: Vigo, Daniel E. Universidad Católica Argentina. Facultad de Ciencias Médicas. Departamento de Docencia e Investigación; Argentina
Fil: Vigo, Daniel E. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Bersenev, Evgeny. Institute of Biomedical Problems of Russian Academia of Science. State Science Center of Russian Federation; Rusia
Fil: Tuerlinckx, Francis. Universidad de Leuven. Departamento de Psicología; Bélgica
Fil: Van den Bergh, Omer. Universidad de Leuven. Departamento de Psicología; Bélgica
Fil: Aubert, André E. University of Leuven. Laboratory of Experimental Cardiology and Interdisciplinary Centre for Space Studies; Bélgica
Abstract: Long-term confinement and microgravity may entail alteration in the regulation of the cardiovascular system. A 105-d pilot study of a Mars mission simulation was conducted to test the cardiovascular response to slow-paced breathing and mental stress. Methods: Finger blood pressure and beat-to-beat heart rate were monitored in six male volunteers taking part in a 105-d Mars mission simulation. Data were collected before, during (Days 35-38, 70-72, and 100), and after confinement. Recordings were performed in the sitting position during 5-min spontaneous breathing, 3-min 12 cycle/min breathing, 3-min 6 cycle/min breathing, and 5-min mental task performance. Results: We found significant U-shaped changes across the confinement period in systolic arterial pressure (SAP), diastolic arterial pressure (DAP), and mean arterial pressure (MAP). In the fi rst month of confinement, mental task performance significantly lowered SAP by 34.23 mmHg and MAP by 19.89 mmHg compared to spontaneous breathing, whereas these changes were reversed during other periods. Furthermore, no differences in arterial pressure and heart rate were found between spontaneous, 12 cycle/min, and 6 cycle/min breathing. Conclusions: Our fi ndings are in line with and extend previous fi ndings on the alteration of blood pressure regulation due to longterm confinement.