Sleep-wake differences in heart rate variability during a 105-day simulated mission to mars

Autores
Vigo, Daniel Eduardo; Ogrinz, Barbara; Wan, Li; Bersenev, Evgeny; Tuerlinckx, Francis; Van Den Bergh, Omer; Aubert, André E.
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Introduction: In prolonged spacefl ights the effect of long-term confinement on the autonomic regulation of the heart is difficult to separate from the effect of prolonged exposure to microgravity or other spacerelated stressors. Our objective was to investigate whether the sleepwake variations in the autonomic control of the heart are specifically altered by long-term confinement during the 105-d pilot study of the Earth-based Mars500 project. Methods: Before (pre), during (T1: 30, T2: 70, and T3: 100 d), and after (post) conflnement, 24-h EKG records were obtained from the six crewmembers that participated in the mission. Sleep and wake periods were determined by fltting a square wave to the data. Autonomic activity was evaluated through time and frequency domain indexes of heart rate variability (HRV) analysis during wake and sleep periods. Results: During conflnement, wake HRV showed decreased mean heart rate and increased amplitude at all frequency levels, particularly in the very low (pre: 13.3 ± 0.2; T1: 13.9 ± 0.3; T2: 13.9 ± 0.2; T3: 13.9 ± 0.2; post: 13.2 ± 0.2) and high (pre: 7.6 ± 0.4; T1: 8.3 ± 0.5; T2: 8.2 ± 0.4; T3: 8.1 ± 0.4; post: 7.6 ± 0.3) frequency components (values expressed as mean 6 SE of wavelet power coefflcients). Sleep HRV remained constant, while sleep-wake high frequency HRV differences diminished. Discussion: The observed autonomic changes during conflnement refl ect an increase in parasympathetic activity during wake periods. Several factors could account for this observation, including reduced daylight exposure related to the conflnement situation.
Fil: Vigo, Daniel Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia
Fil: Ogrinz, Barbara. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina
Fil: Wan, Li. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina
Fil: Bersenev, Evgeny. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina
Fil: Tuerlinckx, Francis. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina
Fil: Van Den Bergh, Omer. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina
Fil: Aubert, André E.. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina
Materia
AUTONOMIC NERVOUS SYSTEM
CONFLNEMENT
MARS500
SPACE PHYSIOLOGY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/195335
Acceder
id CONICETDig_ee2be758e493a1d6109d813142a29e08
oai_identifier_str oai:ri.conicet.gov.ar:11336/195335
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Sleep-wake differences in heart rate variability during a 105-day simulated mission to marsVigo, Daniel EduardoOgrinz, BarbaraWan, LiBersenev, EvgenyTuerlinckx, FrancisVan Den Bergh, OmerAubert, André E.AUTONOMIC NERVOUS SYSTEMCONFLNEMENTMARS500SPACE PHYSIOLOGYhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Introduction: In prolonged spacefl ights the effect of long-term confinement on the autonomic regulation of the heart is difficult to separate from the effect of prolonged exposure to microgravity or other spacerelated stressors. Our objective was to investigate whether the sleepwake variations in the autonomic control of the heart are specifically altered by long-term confinement during the 105-d pilot study of the Earth-based Mars500 project. Methods: Before (pre), during (T1: 30, T2: 70, and T3: 100 d), and after (post) conflnement, 24-h EKG records were obtained from the six crewmembers that participated in the mission. Sleep and wake periods were determined by fltting a square wave to the data. Autonomic activity was evaluated through time and frequency domain indexes of heart rate variability (HRV) analysis during wake and sleep periods. Results: During conflnement, wake HRV showed decreased mean heart rate and increased amplitude at all frequency levels, particularly in the very low (pre: 13.3 ± 0.2; T1: 13.9 ± 0.3; T2: 13.9 ± 0.2; T3: 13.9 ± 0.2; post: 13.2 ± 0.2) and high (pre: 7.6 ± 0.4; T1: 8.3 ± 0.5; T2: 8.2 ± 0.4; T3: 8.1 ± 0.4; post: 7.6 ± 0.3) frequency components (values expressed as mean 6 SE of wavelet power coefflcients). Sleep HRV remained constant, while sleep-wake high frequency HRV differences diminished. Discussion: The observed autonomic changes during conflnement refl ect an increase in parasympathetic activity during wake periods. Several factors could account for this observation, including reduced daylight exposure related to the conflnement situation.Fil: Vigo, Daniel Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; RusiaFil: Ogrinz, Barbara. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; ArgentinaFil: Wan, Li. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; ArgentinaFil: Bersenev, Evgeny. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; ArgentinaFil: Tuerlinckx, Francis. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; ArgentinaFil: Van Den Bergh, Omer. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; ArgentinaFil: Aubert, André E.. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; ArgentinaAerospace Medical Association2012-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/195335Vigo, Daniel Eduardo; Ogrinz, Barbara; Wan, Li; Bersenev, Evgeny; Tuerlinckx, Francis; et al.; Sleep-wake differences in heart rate variability during a 105-day simulated mission to mars; Aerospace Medical Association; Aviation, Space, and Environmental Medicine; 83; 2; 3-2012; 125-1300095-6562CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.ingentaconnect.com/content/asma/asem/2012/00000083/00000002/art00007info:eu-repo/semantics/altIdentifier/doi/10.3357/ASEM.3120.2012info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:00:31Zoai:ri.conicet.gov.ar:11336/195335instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:00:31.961CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Sleep-wake differences in heart rate variability during a 105-day simulated mission to mars
title Sleep-wake differences in heart rate variability during a 105-day simulated mission to mars
spellingShingle Sleep-wake differences in heart rate variability during a 105-day simulated mission to mars
Vigo, Daniel Eduardo
AUTONOMIC NERVOUS SYSTEM
CONFLNEMENT
MARS500
SPACE PHYSIOLOGY
title_short Sleep-wake differences in heart rate variability during a 105-day simulated mission to mars
title_full Sleep-wake differences in heart rate variability during a 105-day simulated mission to mars
title_fullStr Sleep-wake differences in heart rate variability during a 105-day simulated mission to mars
title_full_unstemmed Sleep-wake differences in heart rate variability during a 105-day simulated mission to mars
title_sort Sleep-wake differences in heart rate variability during a 105-day simulated mission to mars
dc.creator.none.fl_str_mv Vigo, Daniel Eduardo
Ogrinz, Barbara
Wan, Li
Bersenev, Evgeny
Tuerlinckx, Francis
Van Den Bergh, Omer
Aubert, André E.
author Vigo, Daniel Eduardo
author_facet Vigo, Daniel Eduardo
Ogrinz, Barbara
Wan, Li
Bersenev, Evgeny
Tuerlinckx, Francis
Van Den Bergh, Omer
Aubert, André E.
author_role author
author2 Ogrinz, Barbara
Wan, Li
Bersenev, Evgeny
Tuerlinckx, Francis
Van Den Bergh, Omer
Aubert, André E.
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv AUTONOMIC NERVOUS SYSTEM
CONFLNEMENT
MARS500
SPACE PHYSIOLOGY
topic AUTONOMIC NERVOUS SYSTEM
CONFLNEMENT
MARS500
SPACE PHYSIOLOGY
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Introduction: In prolonged spacefl ights the effect of long-term confinement on the autonomic regulation of the heart is difficult to separate from the effect of prolonged exposure to microgravity or other spacerelated stressors. Our objective was to investigate whether the sleepwake variations in the autonomic control of the heart are specifically altered by long-term confinement during the 105-d pilot study of the Earth-based Mars500 project. Methods: Before (pre), during (T1: 30, T2: 70, and T3: 100 d), and after (post) conflnement, 24-h EKG records were obtained from the six crewmembers that participated in the mission. Sleep and wake periods were determined by fltting a square wave to the data. Autonomic activity was evaluated through time and frequency domain indexes of heart rate variability (HRV) analysis during wake and sleep periods. Results: During conflnement, wake HRV showed decreased mean heart rate and increased amplitude at all frequency levels, particularly in the very low (pre: 13.3 ± 0.2; T1: 13.9 ± 0.3; T2: 13.9 ± 0.2; T3: 13.9 ± 0.2; post: 13.2 ± 0.2) and high (pre: 7.6 ± 0.4; T1: 8.3 ± 0.5; T2: 8.2 ± 0.4; T3: 8.1 ± 0.4; post: 7.6 ± 0.3) frequency components (values expressed as mean 6 SE of wavelet power coefflcients). Sleep HRV remained constant, while sleep-wake high frequency HRV differences diminished. Discussion: The observed autonomic changes during conflnement refl ect an increase in parasympathetic activity during wake periods. Several factors could account for this observation, including reduced daylight exposure related to the conflnement situation.
Fil: Vigo, Daniel Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia
Fil: Ogrinz, Barbara. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina
Fil: Wan, Li. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina
Fil: Bersenev, Evgeny. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina
Fil: Tuerlinckx, Francis. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina
Fil: Van Den Bergh, Omer. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina
Fil: Aubert, André E.. Katholikie Universiteit Leuven; Bélgica. Russian Academy Of Sciences. Institute For Biomedical Problems; Rusia. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina
description Introduction: In prolonged spacefl ights the effect of long-term confinement on the autonomic regulation of the heart is difficult to separate from the effect of prolonged exposure to microgravity or other spacerelated stressors. Our objective was to investigate whether the sleepwake variations in the autonomic control of the heart are specifically altered by long-term confinement during the 105-d pilot study of the Earth-based Mars500 project. Methods: Before (pre), during (T1: 30, T2: 70, and T3: 100 d), and after (post) conflnement, 24-h EKG records were obtained from the six crewmembers that participated in the mission. Sleep and wake periods were determined by fltting a square wave to the data. Autonomic activity was evaluated through time and frequency domain indexes of heart rate variability (HRV) analysis during wake and sleep periods. Results: During conflnement, wake HRV showed decreased mean heart rate and increased amplitude at all frequency levels, particularly in the very low (pre: 13.3 ± 0.2; T1: 13.9 ± 0.3; T2: 13.9 ± 0.2; T3: 13.9 ± 0.2; post: 13.2 ± 0.2) and high (pre: 7.6 ± 0.4; T1: 8.3 ± 0.5; T2: 8.2 ± 0.4; T3: 8.1 ± 0.4; post: 7.6 ± 0.3) frequency components (values expressed as mean 6 SE of wavelet power coefflcients). Sleep HRV remained constant, while sleep-wake high frequency HRV differences diminished. Discussion: The observed autonomic changes during conflnement refl ect an increase in parasympathetic activity during wake periods. Several factors could account for this observation, including reduced daylight exposure related to the conflnement situation.
publishDate 2012
dc.date.none.fl_str_mv 2012-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/195335
Vigo, Daniel Eduardo; Ogrinz, Barbara; Wan, Li; Bersenev, Evgeny; Tuerlinckx, Francis; et al.; Sleep-wake differences in heart rate variability during a 105-day simulated mission to mars; Aerospace Medical Association; Aviation, Space, and Environmental Medicine; 83; 2; 3-2012; 125-130
0095-6562
CONICET Digital
CONICET
url http://hdl.handle.net/11336/195335
identifier_str_mv Vigo, Daniel Eduardo; Ogrinz, Barbara; Wan, Li; Bersenev, Evgeny; Tuerlinckx, Francis; et al.; Sleep-wake differences in heart rate variability during a 105-day simulated mission to mars; Aerospace Medical Association; Aviation, Space, and Environmental Medicine; 83; 2; 3-2012; 125-130
0095-6562
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.ingentaconnect.com/content/asma/asem/2012/00000083/00000002/art00007
info:eu-repo/semantics/altIdentifier/doi/10.3357/ASEM.3120.2012
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Aerospace Medical Association
publisher.none.fl_str_mv Aerospace Medical Association
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269643378524160
score 13.13397

Publicaciones similares