Diagnosis and management of pain in Parkinson’s disease: a new approach

Autores
Mylius, Veit; Carsten Möller, Jens; Bohlhalter, Stephan; Ciampi de Andrade, Daniel; Pérez Lloret, Santiago
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Fil: Mylius, Veit. Center for Neurorehabilitation. Department of Neurology; Suiza
Fil: Mylius, Veit. Philipps University. Department of Neurology; Alemania
Fil: Mylius, Veit. Kantonsspital St. Gallen. Department of Neurology; Suiza
Fil: Carsten Möller, Jens. Philipps University. Department of Neurology; Alemania
Fil: Carsten Möller, Jens. Parkinson Center. Center for Neurological Rehabilitation; Suiza
Fil: Bohlhalter, Stephan. Luzerner Kantonsspital. Neurocenter; Suiza
Fil:Bohlhalter, Stephan. University of Zurich. Dept. of Neurology; Suiza
Fil: Ciampi de Andrade, Daniel. Universidade de Sao Paulo. Faculdade de Medicina. Departamento de Neurologia. Centro de Dor; Brasil
Fil: Ciampi de Andrade, Daniel. Instituto do Cancer de Sao Paulo Octavio Frias de Oliveira; Brasil
Fil: Ciampi de Andrade, Daniel. Universidade de Sao Paulo. Hospital das Clinicas; Brasil
Fil: Pérez Lloret, Santiago. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Pérez Lloret, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Pérez Lloret, Santiago. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Fisiología; Argentina
Abstract: Pain is a frequent and disabling non-motor feature of Parkinson’s disease (PD). The recently proposed PD Pain Classification System (PD-PCS) allows to determine an association of pain with PD before allocating to the main pain mechanism (i.e. nociceptive, neuropathic, and nociplastic). In this article, previous studies on treatments for pain in PD are summarized according to the pain mechanisms. A mechanistic approach to treatment is discussed. We suggest that the first step should be optimizing dopaminergic therapy before other therapy is started. When these treatments remain unsuccessful, further causes of pain must be considered. The role of drugs, invasive treatments, and physiotherapeutic interventions are discussed with a focus on older PD patients considering polypharmacy, altered pharmacokinetics, and comorbidities.
Fuente
Drugs & Aging. 2021, 38. doi:10.1007/s40266-021-00867-1
Materia
ENFERMEDAD DE PARKINSON
DIAGNOSTICO
DOLOR
TRATAMIENTO MEDICO
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
Repositorio Institucional (UCA)
Institución
Pontificia Universidad Católica Argentina
OAI Identificador
oai:ucacris:123456789/12862
Acceder
id RIUCA_a29d1e7ab8d6007285cfb9d014fe829c
oai_identifier_str oai:ucacris:123456789/12862
network_acronym_str RIUCA
repository_id_str 2585
network_name_str Repositorio Institucional (UCA)
spelling Diagnosis and management of pain in Parkinson’s disease: a new approachMylius, VeitCarsten Möller, JensBohlhalter, StephanCiampi de Andrade, DanielPérez Lloret, SantiagoENFERMEDAD DE PARKINSONDIAGNOSTICODOLORTRATAMIENTO MEDICOFil: Mylius, Veit. Center for Neurorehabilitation. Department of Neurology; SuizaFil: Mylius, Veit. Philipps University. Department of Neurology; AlemaniaFil: Mylius, Veit. Kantonsspital St. Gallen. Department of Neurology; SuizaFil: Carsten Möller, Jens. Philipps University. Department of Neurology; AlemaniaFil: Carsten Möller, Jens. Parkinson Center. Center for Neurological Rehabilitation; SuizaFil: Bohlhalter, Stephan. Luzerner Kantonsspital. Neurocenter; SuizaFil:Bohlhalter, Stephan. University of Zurich. Dept. of Neurology; SuizaFil: Ciampi de Andrade, Daniel. Universidade de Sao Paulo. Faculdade de Medicina. Departamento de Neurologia. Centro de Dor; BrasilFil: Ciampi de Andrade, Daniel. Instituto do Cancer de Sao Paulo Octavio Frias de Oliveira; BrasilFil: Ciampi de Andrade, Daniel. Universidade de Sao Paulo. Hospital das Clinicas; BrasilFil: Pérez Lloret, Santiago. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; ArgentinaFil: Pérez Lloret, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Pérez Lloret, Santiago. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Fisiología; ArgentinaAbstract: Pain is a frequent and disabling non-motor feature of Parkinson’s disease (PD). The recently proposed PD Pain Classification System (PD-PCS) allows to determine an association of pain with PD before allocating to the main pain mechanism (i.e. nociceptive, neuropathic, and nociplastic). In this article, previous studies on treatments for pain in PD are summarized according to the pain mechanisms. A mechanistic approach to treatment is discussed. We suggest that the first step should be optimizing dopaminergic therapy before other therapy is started. When these treatments remain unsuccessful, further causes of pain must be considered. The role of drugs, invasive treatments, and physiotherapeutic interventions are discussed with a focus on older PD patients considering polypharmacy, altered pharmacokinetics, and comorbidities.Springer2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://repositorio.uca.edu.ar/handle/123456789/12862170-229X (impreso)1179-1969 (online)10.1007/s40266-021-00867-134224103Mylius, V., et al. Diagnosis and management of pain in Parkinson’s disease: a new approach [en línea]. Drugs & Aging. 2021, 38. doi:10.1007/s40266-021-00867-1. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/12862Drugs & Aging. 2021, 38. doi:10.1007/s40266-021-00867-1reponame:Repositorio Institucional (UCA)instname:Pontificia Universidad Católica Argentinaenginfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/4.0/2025-07-03T10:58:13Zoai:ucacris:123456789/12862instacron:UCAInstitucionalhttps://repositorio.uca.edu.ar/Universidad privadaNo correspondehttps://repositorio.uca.edu.ar/oaiclaudia_fernandez@uca.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:25852025-07-03 10:58:13.919Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentinafalse
dc.title.none.fl_str_mv Diagnosis and management of pain in Parkinson’s disease: a new approach
title Diagnosis and management of pain in Parkinson’s disease: a new approach
spellingShingle Diagnosis and management of pain in Parkinson’s disease: a new approach
Mylius, Veit
ENFERMEDAD DE PARKINSON
DIAGNOSTICO
DOLOR
TRATAMIENTO MEDICO
title_short Diagnosis and management of pain in Parkinson’s disease: a new approach
title_full Diagnosis and management of pain in Parkinson’s disease: a new approach
title_fullStr Diagnosis and management of pain in Parkinson’s disease: a new approach
title_full_unstemmed Diagnosis and management of pain in Parkinson’s disease: a new approach
title_sort Diagnosis and management of pain in Parkinson’s disease: a new approach
dc.creator.none.fl_str_mv Mylius, Veit
Carsten Möller, Jens
Bohlhalter, Stephan
Ciampi de Andrade, Daniel
Pérez Lloret, Santiago
author Mylius, Veit
author_facet Mylius, Veit
Carsten Möller, Jens
Bohlhalter, Stephan
Ciampi de Andrade, Daniel
Pérez Lloret, Santiago
author_role author
author2 Carsten Möller, Jens
Bohlhalter, Stephan
Ciampi de Andrade, Daniel
Pérez Lloret, Santiago
author2_role author
author
author
author
dc.subject.none.fl_str_mv ENFERMEDAD DE PARKINSON
DIAGNOSTICO
DOLOR
TRATAMIENTO MEDICO
topic ENFERMEDAD DE PARKINSON
DIAGNOSTICO
DOLOR
TRATAMIENTO MEDICO
dc.description.none.fl_txt_mv Fil: Mylius, Veit. Center for Neurorehabilitation. Department of Neurology; Suiza
Fil: Mylius, Veit. Philipps University. Department of Neurology; Alemania
Fil: Mylius, Veit. Kantonsspital St. Gallen. Department of Neurology; Suiza
Fil: Carsten Möller, Jens. Philipps University. Department of Neurology; Alemania
Fil: Carsten Möller, Jens. Parkinson Center. Center for Neurological Rehabilitation; Suiza
Fil: Bohlhalter, Stephan. Luzerner Kantonsspital. Neurocenter; Suiza
Fil:Bohlhalter, Stephan. University of Zurich. Dept. of Neurology; Suiza
Fil: Ciampi de Andrade, Daniel. Universidade de Sao Paulo. Faculdade de Medicina. Departamento de Neurologia. Centro de Dor; Brasil
Fil: Ciampi de Andrade, Daniel. Instituto do Cancer de Sao Paulo Octavio Frias de Oliveira; Brasil
Fil: Ciampi de Andrade, Daniel. Universidade de Sao Paulo. Hospital das Clinicas; Brasil
Fil: Pérez Lloret, Santiago. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Pérez Lloret, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Pérez Lloret, Santiago. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Fisiología; Argentina
Abstract: Pain is a frequent and disabling non-motor feature of Parkinson’s disease (PD). The recently proposed PD Pain Classification System (PD-PCS) allows to determine an association of pain with PD before allocating to the main pain mechanism (i.e. nociceptive, neuropathic, and nociplastic). In this article, previous studies on treatments for pain in PD are summarized according to the pain mechanisms. A mechanistic approach to treatment is discussed. We suggest that the first step should be optimizing dopaminergic therapy before other therapy is started. When these treatments remain unsuccessful, further causes of pain must be considered. The role of drugs, invasive treatments, and physiotherapeutic interventions are discussed with a focus on older PD patients considering polypharmacy, altered pharmacokinetics, and comorbidities.
description Fil: Mylius, Veit. Center for Neurorehabilitation. Department of Neurology; Suiza
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://repositorio.uca.edu.ar/handle/123456789/12862
170-229X (impreso)
1179-1969 (online)
10.1007/s40266-021-00867-1
34224103
Mylius, V., et al. Diagnosis and management of pain in Parkinson’s disease: a new approach [en línea]. Drugs & Aging. 2021, 38. doi:10.1007/s40266-021-00867-1. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/12862
url https://repositorio.uca.edu.ar/handle/123456789/12862
identifier_str_mv 170-229X (impreso)
1179-1969 (online)
10.1007/s40266-021-00867-1
34224103
Mylius, V., et al. Diagnosis and management of pain in Parkinson’s disease: a new approach [en línea]. Drugs & Aging. 2021, 38. doi:10.1007/s40266-021-00867-1. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/12862
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0/
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv Drugs & Aging. 2021, 38. doi:10.1007/s40266-021-00867-1
reponame:Repositorio Institucional (UCA)
instname:Pontificia Universidad Católica Argentina
reponame_str Repositorio Institucional (UCA)
collection Repositorio Institucional (UCA)
instname_str Pontificia Universidad Católica Argentina
repository.name.fl_str_mv Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentina
repository.mail.fl_str_mv claudia_fernandez@uca.edu.ar
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score 13.070432

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