Open-access electronic diary for motor fluctuation and dyskinesia evaluation in aprkinson disease: comparison with paper diary

Autores
Terroba Chambi, Cinthia; Bruno, Verónica; Medina Escobar, Alex; Nanni, Federico; Cerquetti, Daniel; Rossi, Malco Damián; Merello, Marcelo
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Fil: Terroba Chambi, Cinthia. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Terroba Chambi, Cinthia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Terroba Chambi, Cinthia. Fleni. Departamento de Neurociencias; Argentina
Fil: Bruno, Veronica. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Bruno, Veronica. Fleni. Departamento de Neurociencias; Argentina
Fil: Bruno, Veronica. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Medina Escobar, Alex. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Medina Escobar, Alex. Fleni. Departamento de Neurociencias; Argentina
Fil: Nanni, Federico. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Nanni, Federico. Fleni. Departamento de Neurociencias; Argentina
Fil: Cerquetti, Daniel. Fleni. Departamento de Neurociencias; Argentina
Fil: Cerquetti, Daniel. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Rossi, Malco Damián. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Rossi, Malco Damián. Fleni. Departamento de Neurociencias; Argentina
Fil: Merello, Marcelo. Fleni. Departamento de Neurociencias; Argentina
Fil: Merello, Marcelo. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Merello, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Abstract: Objective - To determine the utility of an electronic diary for registering motor fluctuations and dyskinesia in Parkinson disease (PD). Methods - Free, open-access touch screen software suitable for Android 4.4 or higher, with medication alarms, adjustable intervals, and medication dose settings was developed to evaluate ON-OFF periods and dyskinesia. Prospective evaluation included a first phase conducted to make adjustments concerning motor limitations when using the tablet, as well as for proper motor complication identification, and a second phase of 3 days of use at home with a prior diary training session comparing a modified paper version of Core Assessment Program for Surgical Interventional Therapies in PD and the electronic diary. Results - All patients correctly identified ON-OFF periods and dyskinesia. Rater/patient matching ON-OFF fluctuations ranged between 94% and 100% for evaluations of different motor states. Dyskinesia matching percentage was 100% for patients with dyskinesia interfering with activities of daily living and 88% for those who reported no-interference. No significant differences between paper and electronic diaries were identified when reporting ON-OFF motor states or in the number of errors when filling the diaries. Conclusions - This electronic motor diary proved to be reliable for ON-OFF state and dyskinesia identification and classification. However, no advantage to paper diary has been observed in terms of number of erroneous entries. Based on these results, to improve home motor fluctuations, detection efforts should be directed toward the development of automatic wearable devices rather than digital versions of current available ON-OFF diaries.
Fuente
Clinical Neuropharmacology. 2018, 41
Materia
ENFERMEDAD DE PARKINSON
VIDA COTIDIANA
ENVEJECIMIENTO
DISCINESIA
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
Repositorio Institucional (UCA)
Institución
Pontificia Universidad Católica Argentina
OAI Identificador
oai:ucacris:123456789/15115
Acceder
id RIUCA_68136746222ec9f203a8e382575372c3
oai_identifier_str oai:ucacris:123456789/15115
network_acronym_str RIUCA
repository_id_str 2585
network_name_str Repositorio Institucional (UCA)
spelling Open-access electronic diary for motor fluctuation and dyskinesia evaluation in aprkinson disease: comparison with paper diaryTerroba Chambi, CinthiaBruno, VerónicaMedina Escobar, AlexNanni, FedericoCerquetti, DanielRossi, Malco DamiánMerello, MarceloENFERMEDAD DE PARKINSONVIDA COTIDIANAENVEJECIMIENTODISCINESIAFil: Terroba Chambi, Cinthia. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; ArgentinaFil: Terroba Chambi, Cinthia. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Terroba Chambi, Cinthia. Fleni. Departamento de Neurociencias; ArgentinaFil: Bruno, Veronica. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; ArgentinaFil: Bruno, Veronica. Fleni. Departamento de Neurociencias; ArgentinaFil: Bruno, Veronica. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Medina Escobar, Alex. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; ArgentinaFil: Medina Escobar, Alex. Fleni. Departamento de Neurociencias; ArgentinaFil: Nanni, Federico. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; ArgentinaFil: Nanni, Federico. Fleni. Departamento de Neurociencias; ArgentinaFil: Cerquetti, Daniel. Fleni. Departamento de Neurociencias; ArgentinaFil: Cerquetti, Daniel. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; ArgentinaFil: Rossi, Malco Damián. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; ArgentinaFil: Rossi, Malco Damián. Fleni. Departamento de Neurociencias; ArgentinaFil: Merello, Marcelo. Fleni. Departamento de Neurociencias; ArgentinaFil: Merello, Marcelo. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; ArgentinaFil: Merello, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaAbstract: Objective - To determine the utility of an electronic diary for registering motor fluctuations and dyskinesia in Parkinson disease (PD). Methods - Free, open-access touch screen software suitable for Android 4.4 or higher, with medication alarms, adjustable intervals, and medication dose settings was developed to evaluate ON-OFF periods and dyskinesia. Prospective evaluation included a first phase conducted to make adjustments concerning motor limitations when using the tablet, as well as for proper motor complication identification, and a second phase of 3 days of use at home with a prior diary training session comparing a modified paper version of Core Assessment Program for Surgical Interventional Therapies in PD and the electronic diary. Results - All patients correctly identified ON-OFF periods and dyskinesia. Rater/patient matching ON-OFF fluctuations ranged between 94% and 100% for evaluations of different motor states. Dyskinesia matching percentage was 100% for patients with dyskinesia interfering with activities of daily living and 88% for those who reported no-interference. No significant differences between paper and electronic diaries were identified when reporting ON-OFF motor states or in the number of errors when filling the diaries. Conclusions - This electronic motor diary proved to be reliable for ON-OFF state and dyskinesia identification and classification. However, no advantage to paper diary has been observed in terms of number of erroneous entries. Based on these results, to improve home motor fluctuations, detection efforts should be directed toward the development of automatic wearable devices rather than digital versions of current available ON-OFF diaries.Wolters Kluwer2018info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://repositorio.uca.edu.ar/handle/123456789/151150362-56641537-162X (online)10.1097/WNF.000000000000026429303799Terroba Chambi, C.J. et al. Open-access electronic diary for motor fluctuation and dyskinesia evaluation in aprkinson disease: comparison with paper diary [en línea]. Clinical Neuropharmacology. 2018, 41(1) doi:10.1097/WNF.0000000000000264 Disponible en: https://repositorio.uca.edu.ar/handle/123456789/15115Clinical Neuropharmacology. 2018, 41reponame:Repositorio Institucional (UCA)instname:Pontificia Universidad Católica Argentinaenginfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/4.0/2025-07-03T10:58:51Zoai:ucacris:123456789/15115instacron:UCAInstitucionalhttps://repositorio.uca.edu.ar/Universidad privadaNo correspondehttps://repositorio.uca.edu.ar/oaiclaudia_fernandez@uca.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:25852025-07-03 10:58:52.097Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentinafalse
dc.title.none.fl_str_mv Open-access electronic diary for motor fluctuation and dyskinesia evaluation in aprkinson disease: comparison with paper diary
title Open-access electronic diary for motor fluctuation and dyskinesia evaluation in aprkinson disease: comparison with paper diary
spellingShingle Open-access electronic diary for motor fluctuation and dyskinesia evaluation in aprkinson disease: comparison with paper diary
Terroba Chambi, Cinthia
ENFERMEDAD DE PARKINSON
VIDA COTIDIANA
ENVEJECIMIENTO
DISCINESIA
title_short Open-access electronic diary for motor fluctuation and dyskinesia evaluation in aprkinson disease: comparison with paper diary
title_full Open-access electronic diary for motor fluctuation and dyskinesia evaluation in aprkinson disease: comparison with paper diary
title_fullStr Open-access electronic diary for motor fluctuation and dyskinesia evaluation in aprkinson disease: comparison with paper diary
title_full_unstemmed Open-access electronic diary for motor fluctuation and dyskinesia evaluation in aprkinson disease: comparison with paper diary
title_sort Open-access electronic diary for motor fluctuation and dyskinesia evaluation in aprkinson disease: comparison with paper diary
dc.creator.none.fl_str_mv Terroba Chambi, Cinthia
Bruno, Verónica
Medina Escobar, Alex
Nanni, Federico
Cerquetti, Daniel
Rossi, Malco Damián
Merello, Marcelo
author Terroba Chambi, Cinthia
author_facet Terroba Chambi, Cinthia
Bruno, Verónica
Medina Escobar, Alex
Nanni, Federico
Cerquetti, Daniel
Rossi, Malco Damián
Merello, Marcelo
author_role author
author2 Bruno, Verónica
Medina Escobar, Alex
Nanni, Federico
Cerquetti, Daniel
Rossi, Malco Damián
Merello, Marcelo
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv ENFERMEDAD DE PARKINSON
VIDA COTIDIANA
ENVEJECIMIENTO
DISCINESIA
topic ENFERMEDAD DE PARKINSON
VIDA COTIDIANA
ENVEJECIMIENTO
DISCINESIA
dc.description.none.fl_txt_mv Fil: Terroba Chambi, Cinthia. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Terroba Chambi, Cinthia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Terroba Chambi, Cinthia. Fleni. Departamento de Neurociencias; Argentina
Fil: Bruno, Veronica. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Bruno, Veronica. Fleni. Departamento de Neurociencias; Argentina
Fil: Bruno, Veronica. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Medina Escobar, Alex. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Medina Escobar, Alex. Fleni. Departamento de Neurociencias; Argentina
Fil: Nanni, Federico. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Nanni, Federico. Fleni. Departamento de Neurociencias; Argentina
Fil: Cerquetti, Daniel. Fleni. Departamento de Neurociencias; Argentina
Fil: Cerquetti, Daniel. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Rossi, Malco Damián. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Rossi, Malco Damián. Fleni. Departamento de Neurociencias; Argentina
Fil: Merello, Marcelo. Fleni. Departamento de Neurociencias; Argentina
Fil: Merello, Marcelo. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Merello, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Abstract: Objective - To determine the utility of an electronic diary for registering motor fluctuations and dyskinesia in Parkinson disease (PD). Methods - Free, open-access touch screen software suitable for Android 4.4 or higher, with medication alarms, adjustable intervals, and medication dose settings was developed to evaluate ON-OFF periods and dyskinesia. Prospective evaluation included a first phase conducted to make adjustments concerning motor limitations when using the tablet, as well as for proper motor complication identification, and a second phase of 3 days of use at home with a prior diary training session comparing a modified paper version of Core Assessment Program for Surgical Interventional Therapies in PD and the electronic diary. Results - All patients correctly identified ON-OFF periods and dyskinesia. Rater/patient matching ON-OFF fluctuations ranged between 94% and 100% for evaluations of different motor states. Dyskinesia matching percentage was 100% for patients with dyskinesia interfering with activities of daily living and 88% for those who reported no-interference. No significant differences between paper and electronic diaries were identified when reporting ON-OFF motor states or in the number of errors when filling the diaries. Conclusions - This electronic motor diary proved to be reliable for ON-OFF state and dyskinesia identification and classification. However, no advantage to paper diary has been observed in terms of number of erroneous entries. Based on these results, to improve home motor fluctuations, detection efforts should be directed toward the development of automatic wearable devices rather than digital versions of current available ON-OFF diaries.
description Fil: Terroba Chambi, Cinthia. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
publishDate 2018
dc.date.none.fl_str_mv 2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://repositorio.uca.edu.ar/handle/123456789/15115
0362-5664
1537-162X (online)
10.1097/WNF.0000000000000264
29303799
Terroba Chambi, C.J. et al. Open-access electronic diary for motor fluctuation and dyskinesia evaluation in aprkinson disease: comparison with paper diary [en línea]. Clinical Neuropharmacology. 2018, 41(1) doi:10.1097/WNF.0000000000000264 Disponible en: https://repositorio.uca.edu.ar/handle/123456789/15115
url https://repositorio.uca.edu.ar/handle/123456789/15115
identifier_str_mv 0362-5664
1537-162X (online)
10.1097/WNF.0000000000000264
29303799
Terroba Chambi, C.J. et al. Open-access electronic diary for motor fluctuation and dyskinesia evaluation in aprkinson disease: comparison with paper diary [en línea]. Clinical Neuropharmacology. 2018, 41(1) doi:10.1097/WNF.0000000000000264 Disponible en: https://repositorio.uca.edu.ar/handle/123456789/15115
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0/
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wolters Kluwer
publisher.none.fl_str_mv Wolters Kluwer
dc.source.none.fl_str_mv Clinical Neuropharmacology. 2018, 41
reponame:Repositorio Institucional (UCA)
instname:Pontificia Universidad Católica Argentina
reponame_str Repositorio Institucional (UCA)
collection Repositorio Institucional (UCA)
instname_str Pontificia Universidad Católica Argentina
repository.name.fl_str_mv Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentina
repository.mail.fl_str_mv claudia_fernandez@uca.edu.ar
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score 13.070432

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